메뉴 건너뛰기




Volumn 15, Issue 1, 2015, Pages

Prospective, randomized, double-blind trial to investigate the efficacy and safety of corneal cross-linking to halt the progression of keratoconus

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; CROSS LINKING REAGENT; PHOTOSENSITIZING AGENT; RIBOFLAVIN;

EID: 84937243022     PISSN: None     EISSN: 14712415     Source Type: Journal    
DOI: 10.1186/s12886-015-0070-7     Document Type: Article
Times cited : (49)

References (42)
  • 1
    • 0021343891 scopus 로고
    • Keratoconus and related noninflammatory corneal thinning disorders
    • 1:STN:280:DyaL2c7kslCksA%3D%3D 6230745
    • Krachmer JH, Feder RS, Belin MW. Keratoconus and related noninflammatory corneal thinning disorders. Surv Ophthalmol. 1984;28:293-322.
    • (1984) Surv Ophthalmol , vol.28 , pp. 293-322
    • Krachmer, J.H.1    Feder, R.S.2    Belin, M.W.3
  • 3
    • 84861097225 scopus 로고    scopus 로고
    • What causes keratoconus?
    • 22406940
    • Sugar J, Macsai MS. What causes keratoconus? Cornea. 2012;31:716-9.
    • (2012) Cornea , vol.31 , pp. 716-719
    • Sugar, J.1    Macsai, M.S.2
  • 4
    • 0021792234 scopus 로고
    • The ocular features of Down's syndrome
    • 1:STN:280:DyaL2M3kvVOntw%3D%3D 3160242
    • Shapiro MB, France TD. The ocular features of Down's syndrome. Am J Ophthalmol. 1985;99:659-63.
    • (1985) Am J Ophthalmol , vol.99 , pp. 659-663
    • Shapiro, M.B.1    France, T.D.2
  • 5
    • 0033902602 scopus 로고    scopus 로고
    • Atopy and keratoconus: A multivariate analysis
    • 1:STN:280:DC%2BD3cvhslClsQ%3D%3D 1723585 10906086
    • Bawazeer A, Hodge W, Lorimer B. Atopy and keratoconus: a multivariate analysis. Br J Ophthalmol. 2000;84:834-6.
    • (2000) Br J Ophthalmol , vol.84 , pp. 834-836
    • Bawazeer, A.1    Hodge, W.2    Lorimer, B.3
  • 6
    • 0031914254 scopus 로고    scopus 로고
    • Keratoconus
    • 1:STN:280:DyaK1c7lsVehtg%3D%3D 9493273
    • Rabinowitz YS. Keratoconus. Surv Ophthalmol. 1998;42:297-319.
    • (1998) Surv Ophthalmol , vol.42 , pp. 297-319
    • Rabinowitz, Y.S.1
  • 7
    • 80054724179 scopus 로고    scopus 로고
    • Keratoconus: Clinical aspects, diagnosis, therapeutic possibilities
    • 21913164 quiz 941-2
    • Bühren J, Bischoff G, Kohnen T. Keratoconus: clinical aspects, diagnosis, therapeutic possibilities. Klin Monbl Augenheilkd. 2011;228:923-40. quiz 941-2.
    • (2011) Klin Monbl Augenheilkd , vol.228 , pp. 923-940
    • Bühren, J.1    Bischoff, G.2    Kohnen, T.3
  • 9
    • 0031941909 scopus 로고    scopus 로고
    • Induction of cross-links in corneal tissue
    • 1:CAS:528:DyaK1cXmsV2kuw%3D%3D 9533835
    • Spoerl E, Huhle M, Seiler T. Induction of cross-links in corneal tissue. Exp Eye Res. 1998;66:97-103.
    • (1998) Exp Eye Res , vol.66 , pp. 97-103
    • Spoerl, E.1    Huhle, M.2    Seiler, T.3
  • 10
    • 1542513294 scopus 로고    scopus 로고
    • Thermomechanical behavior of collagen-cross-linked porcine cornea
    • 1:CAS:528:DC%2BD2cXhvVWms7Y%3D 15004504
    • Spoerl E, Wollensak G, Dittert D-D, Seiler T. Thermomechanical behavior of collagen-cross-linked porcine cornea. Ophthalmologica. 2004;218:136-40.
    • (2004) Ophthalmologica , vol.218 , pp. 136-140
    • Spoerl, E.1    Wollensak, G.2    Dittert, D.-D.3    Seiler, T.4
  • 11
    • 1542667180 scopus 로고    scopus 로고
    • Collagen fiber diameter in the rabbit cornea after collagen crosslinking by riboflavin/UVA
    • 15220736
    • Wollensak G, Wilsch M, Spoerl E, Seiler T. Collagen fiber diameter in the rabbit cornea after collagen crosslinking by riboflavin/UVA. Cornea. 2004;23:503-7.
    • (2004) Cornea , vol.23 , pp. 503-507
    • Wollensak, G.1    Wilsch, M.2    Spoerl, E.3    Seiler, T.4
  • 12
    • 79961160040 scopus 로고    scopus 로고
    • Riboflavin/UVA collagen cross-linking-induced changes in normal and keratoconus corneal stroma
    • 1:CAS:528:DC%2BC3MXhtFajt7vP 3151245 21850225
    • Hayes S, Boote C, Kamma-Lorger CS, Rajan MS, Harris J, Dooley E, et al. Riboflavin/UVA collagen cross-linking-induced changes in normal and keratoconus corneal stroma. PLoS One. 2011;6:e22405.
    • (2011) PLoS One , vol.6 , pp. 22405
    • Hayes, S.1    Boote, C.2    Kamma-Lorger, C.S.3    Rajan, M.S.4    Harris, J.5    Dooley, E.6
  • 13
    • 1542667179 scopus 로고    scopus 로고
    • Increased resistance of crosslinked cornea against enzymatic digestion
    • 1:CAS:528:DC%2BD2cXhtVGjs77K 15370365
    • Spoerl E, Wollensak G, Seiler T. Increased resistance of crosslinked cornea against enzymatic digestion. Curr Eye Res. 2004;29:35-40.
    • (2004) Curr Eye Res , vol.29 , pp. 35-40
    • Spoerl, E.1    Wollensak, G.2    Seiler, T.3
  • 14
    • 79957903293 scopus 로고    scopus 로고
    • Effect of various compositions of riboflavin eye drops on the intraoperative corneal thickness during UVA-cross-linking in keratoconus eyes
    • 1:STN:280:DC%2BC3Mjhs1Kisw%3D%3D 21656433
    • Vetter JM, Tubic-Grozdanis M, Faust M, Lorenz K, Gericke A, Stoffelns BM. Effect of various compositions of riboflavin eye drops on the intraoperative corneal thickness during UVA-cross-linking in keratoconus eyes. Klin Monbl Augenheilkd. 2011;228:509-14.
    • (2011) Klin Monbl Augenheilkd , vol.228 , pp. 509-514
    • Vetter, J.M.1    Tubic-Grozdanis, M.2    Faust, M.3    Lorenz, K.4    Gericke, A.5    Stoffelns, B.M.6
  • 15
    • 84872936114 scopus 로고    scopus 로고
    • Morphological and immunohistochemical changes after corneal cross-linking
    • 22580432
    • Messmer EM, Meyer P, Herwig MC, Loeffler KU, Schirra F, Seitz B, et al. Morphological and immunohistochemical changes after corneal cross-linking. Cornea. 2013;32:111-7.
    • (2013) Cornea , vol.32 , pp. 111-117
    • Messmer, E.M.1    Meyer, P.2    Herwig, M.C.3    Loeffler, K.U.4    Schirra, F.5    Seitz, B.6
  • 16
    • 0037405409 scopus 로고    scopus 로고
    • Riboflavin/ultraviolet-A-Induced collagen crosslinking for the treatment of keratoconus
    • 1:CAS:528:DC%2BD3sXjt1Knsbk%3D 12719068
    • Wollensak G, Spoerl E, Seiler T. Riboflavin/ultraviolet-a-induced collagen crosslinking for the treatment of keratoconus. Am J Ophthalmol. 2003;135:620-7.
    • (2003) Am J Ophthalmol , vol.135 , pp. 620-627
    • Wollensak, G.1    Spoerl, E.2    Seiler, T.3
  • 17
    • 79957925140 scopus 로고    scopus 로고
    • Corneal riboflavin/UV-A collagen cross-linking (CXL) in keratoconus: Two-year results
    • 1:STN:280:DC%2BC3Mjhs1KisQ%3D%3D 21656435
    • Kampik D, Koch M, Kampik K, Geerling G. Corneal riboflavin/UV-A collagen cross-linking (CXL) in keratoconus: two-year results. Klin Monbl Augenheilkd. 2011;228:525-30.
    • (2011) Klin Monbl Augenheilkd , vol.228 , pp. 525-530
    • Kampik, D.1    Koch, M.2    Kampik, K.3    Geerling, G.4
  • 18
    • 42949106495 scopus 로고    scopus 로고
    • Collagen crosslinking with riboflavin and ultraviolet-A light in keratoconus: Long-term results
    • 18471635
    • Raiskup-Wolf F, Hoyer A, Spoerl E, Pillunat LE. Collagen crosslinking with riboflavin and ultraviolet-A light in keratoconus: long-term results. J Cataract Refract Surg. 2008;34:796-801.
    • (2008) J Cataract Refract Surg , vol.34 , pp. 796-801
    • Raiskup-Wolf, F.1    Hoyer, A.2    Spoerl, E.3    Pillunat, L.E.4
  • 19
    • 84856590989 scopus 로고    scopus 로고
    • Corneal crosslinking for keratoconus in Iranian patients: Outcomes at 1 year following treatment
    • 2991457 21180440
    • Saffarian L, Khakshoor H, Zarei-Ghanavati M, Esmaily H. Corneal crosslinking for keratoconus in Iranian patients: Outcomes at 1 year following treatment. Middle East Afr J Ophthalmol. 2010;17:365-8.
    • (2010) Middle East Afr J Ophthalmol , vol.17 , pp. 365-368
    • Saffarian, L.1    Khakshoor, H.2    Zarei-Ghanavati, M.3    Esmaily, H.4
  • 20
    • 79960588489 scopus 로고    scopus 로고
    • Flattening of the cornea after collagen crosslinking for keratoconus
    • 21782091
    • Koller T, Pajic B, Vinciguerra P, Seiler T. Flattening of the cornea after collagen crosslinking for keratoconus. J Cataract Refract Surg. 2011;37:1488-92.
    • (2011) J Cataract Refract Surg , vol.37 , pp. 1488-1492
    • Koller, T.1    Pajic, B.2    Vinciguerra, P.3    Seiler, T.4
  • 21
    • 81855212616 scopus 로고    scopus 로고
    • Corneal collagen crosslinking in progressive keratoconus: Multicenter results from the French National Reference Center for Keratoconus
    • 22108109
    • Asri D, Touboul D, Fournié P, Malet F, Garra C, Gallois A, et al. Corneal collagen crosslinking in progressive keratoconus: multicenter results from the French National Reference Center for Keratoconus. J Cataract Refract Surg. 2011;37:2137-43.
    • (2011) J Cataract Refract Surg , vol.37 , pp. 2137-2143
    • Asri, D.1    Touboul, D.2    Fournié, P.3    Malet, F.4    Garra, C.5    Gallois, A.6
  • 23
    • 84881085732 scopus 로고    scopus 로고
    • Prospective longitudinal study of corneal collagen crosslinking in progressive keratoconus
    • 23145528
    • Viswanathan D, Males J. Prospective longitudinal study of corneal collagen crosslinking in progressive keratoconus. Clin Experiment Ophthalmol. 2013;41:531-6.
    • (2013) Clin Experiment Ophthalmol , vol.41 , pp. 531-536
    • Viswanathan, D.1    Males, J.2
  • 24
    • 51149111856 scopus 로고    scopus 로고
    • A randomized controlled trial of corneal collagen cross-linking in progressive keratoconus: Preliminary results
    • 18811118
    • Wittig-Silva C, Whiting M, Lamoureux E, Lindsay RG, Sullivan LJ, Snibson GR. A randomized controlled trial of corneal collagen cross-linking in progressive keratoconus: preliminary results. J Refract Surg. 2008;24:S720-5.
    • (2008) J Refract Surg , vol.24 , pp. 720-725
    • Wittig-Silva, C.1    Whiting, M.2    Lamoureux, E.3    Lindsay, R.G.4    Sullivan, L.J.5    Snibson, G.R.6
  • 25
    • 84897954232 scopus 로고    scopus 로고
    • A randomized, controlled trial of corneal collagen cross-linking in progressive keratoconus: Three-year results
    • 24393351
    • Wittig-Silva C, Chan E, Islam FMA, Wu T, Whiting M, Snibson GR. A randomized, controlled trial of corneal collagen cross-linking in progressive keratoconus: Three-year results. Ophthalmology. 2014;121:812-21.
    • (2014) Ophthalmology , vol.121 , pp. 812-821
    • Wittig-Silva, C.1    Chan, E.2    Islam, F.M.A.3    Wu, T.4    Whiting, M.5    Snibson, G.R.6
  • 26
    • 78650462763 scopus 로고    scopus 로고
    • Corneal collagen crosslinking for keratoconus and corneal ectasia: One-year results
    • 21183110
    • Hersh PS, Greenstein SA, Fry KL. Corneal collagen crosslinking for keratoconus and corneal ectasia: One-year results. J Cataract Refract Surg. 2011;37:149-60.
    • (2011) J Cataract Refract Surg , vol.37 , pp. 149-160
    • Hersh, P.S.1    Greenstein, S.A.2    Fry, K.L.3
  • 27
    • 79959542078 scopus 로고    scopus 로고
    • Corneal topography indices after corneal collagen crosslinking for keratoconus and corneal ectasia: One-year results
    • 21700105
    • Greenstein SA, Fry KL, Hersh PS. Corneal topography indices after corneal collagen crosslinking for keratoconus and corneal ectasia: one-year results. J Cataract Refract Surg. 2011;37:1282-90.
    • (2011) J Cataract Refract Surg , vol.37 , pp. 1282-1290
    • Greenstein, S.A.1    Fry, K.L.2    Hersh, P.S.3
  • 28
    • 80054886097 scopus 로고    scopus 로고
    • A randomised, prospective study to investigate the efficacy of riboflavin/ultraviolet A (370 nm) corneal collagen cross-linkage to halt the progression of keratoconus
    • 21349938
    • O'Brart DPS, Chan E, Samaras K, Patel P, Shah SP. A randomised, prospective study to investigate the efficacy of riboflavin/ultraviolet A (370 nm) corneal collagen cross-linkage to halt the progression of keratoconus. Br J Ophthalmol. 2011;95:1519-24.
    • (2011) Br J Ophthalmol , vol.95 , pp. 1519-1524
    • O'Brart, D.P.S.1    Chan, E.2    Samaras, K.3    Patel, P.4    Shah, S.P.5
  • 29
    • 84947032861 scopus 로고    scopus 로고
    • Collagen cross-linking in keratoconus in Asian eyes: Visual, refractive and confocal microscopy outcomes in a prospective randomized controlled trial
    • Feb, [Epub ahead of print]
    • Sharma N, Suri K, Sehra SV, Titiyal JS, Sinha R, Tandon R, Vajpayee RB. Collagen cross-linking in keratoconus in Asian eyes: visual, refractive and confocal microscopy outcomes in a prospective randomized controlled trial. Int Ophthalmol. Feb 2015 [Epub ahead of print].
    • (2015) Int Ophthalmol
    • Sharma, N.1    Suri, K.2    Sehra, S.V.3    Titiyal, J.S.4    Sinha, R.5    Tandon, R.6    Vajpayee, R.B.7
  • 31
    • 39149089323 scopus 로고    scopus 로고
    • Corneal melting after cross-linking and deep lamellar keratoplasty in a keratoconus patient
    • 1:STN:280:DC%2BD1c7nvFOisQ%3D%3D 18236379
    • Eberwein P, Auw-Hädrich C, Birnbaum F, Maier PC, Reinhard T. Corneal melting after cross-linking and deep lamellar keratoplasty in a keratoconus patient. Klin Monbl Augenheilkd. 2008;225:96-8.
    • (2008) Klin Monbl Augenheilkd , vol.225 , pp. 96-98
    • Eberwein, P.1    Auw-Hädrich, C.2    Birnbaum, F.3    Maier, P.C.4    Reinhard, T.5
  • 32
    • 78649521826 scopus 로고    scopus 로고
    • Natural history of corneal haze after collagen crosslinking for keratoconus and corneal ectasia: Scheimpflug and biomicroscopic analysis
    • 21111314
    • Greenstein SA, Fry KL, Bhatt J, Hersh PS. Natural history of corneal haze after collagen crosslinking for keratoconus and corneal ectasia: Scheimpflug and biomicroscopic analysis. J Cataract Refract Surg. 2010;36:2105-14.
    • (2010) J Cataract Refract Surg , vol.36 , pp. 2105-2114
    • Greenstein, S.A.1    Fry, K.L.2    Bhatt, J.3    Hersh, P.S.4
  • 33
    • 84871409263 scopus 로고    scopus 로고
    • Corneal endothelial loss after crosslinking with riboflavin and ultraviolet-A
    • 22868444
    • Lange C, Böhringer D, Reinhard T. Corneal endothelial loss after crosslinking with riboflavin and ultraviolet-A. Graefes Arch Clin Exp Ophthalmol. 2012;250:1689-91.
    • (2012) Graefes Arch Clin Exp Ophthalmol , vol.250 , pp. 1689-1691
    • Lange, C.1    Böhringer, D.2    Reinhard, T.3
  • 34
    • 52949147774 scopus 로고    scopus 로고
    • Haze or calcific band keratopathy after crosslinking treatment?
    • 1:STN:280:DC%2BD1cnit1aruw%3D%3D 18791720
    • Wollensak G, Hammer T, Herrmann CIA. Haze or calcific band keratopathy after crosslinking treatment? Ophthalmologe. 2008;105:864-5.
    • (2008) Ophthalmologe , vol.105 , pp. 864-865
    • Wollensak, G.1    Hammer, T.2    Herrmann, C.I.A.3
  • 35
    • 67650761046 scopus 로고    scopus 로고
    • Complication and failure rates after corneal crosslinking
    • 19631120
    • Koller T, Mrochen M, Seiler T. Complication and failure rates after corneal crosslinking. J Cataract Refract Surg. 2009;35:1358-62.
    • (2009) J Cataract Refract Surg , vol.35 , pp. 1358-1362
    • Koller, T.1    Mrochen, M.2    Seiler, T.3
  • 36
    • 84883454897 scopus 로고    scopus 로고
    • Riboflavin UVA cross-linking for keratoconus
    • 1:CAS:528:DC%2BC3sXhsVSns7%2FO 23760423
    • Maier P, Reinhard T. Riboflavin UVA cross-linking for keratoconus. Ophthalmologe. 2013;110:818-22.
    • (2013) Ophthalmologe , vol.110 , pp. 818-822
    • Maier, P.1    Reinhard, T.2
  • 37
    • 34548098139 scopus 로고    scopus 로고
    • Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study: Methods and findings to date
    • 1:STN:280:DC%2BD2snhvFejtA%3D%3D 3966142 17481941
    • Wagner H, Barr JT, Zadnik K. Collaborative Longitudinal Evaluation of Keratoconus (CLEK) Study: methods and findings to date. Cont Lens Anterior Eye. 2007;30:223-32.
    • (2007) Cont Lens Anterior Eye , vol.30 , pp. 223-232
    • Wagner, H.1    Barr, J.T.2    Zadnik, K.3
  • 39
    • 84923586596 scopus 로고    scopus 로고
    • Variability in Oculus Pentacam tomographer measurements in patients with keratoconus
    • 25625364
    • Vianna LMM, Muñoz B, Hwang FS, Gupta A, Jun AS. Variability in Oculus Pentacam tomographer measurements in patients with keratoconus. Cornea. 2015;34:285-9.
    • (2015) Cornea , vol.34 , pp. 285-289
    • Vianna, L.M.M.1    Muñoz, B.2    Hwang, F.S.3    Gupta, A.4    Jun, A.S.5
  • 40
    • 84920718866 scopus 로고    scopus 로고
    • Reduced precision of the Pentacam HR in eyes with mild to moderate keratoconus
    • 25444349
    • Hashemi K, Guber I, Bergin C, Majo F. Reduced precision of the Pentacam HR in eyes with mild to moderate keratoconus. Ophthalmology. 2015;122:211-2.
    • (2015) Ophthalmology , vol.122 , pp. 211-212
    • Hashemi, K.1    Guber, I.2    Bergin, C.3    Majo, F.4
  • 41
    • 84857639740 scopus 로고    scopus 로고
    • Reliability and repeatability of swept-source Fourier-domain optical coherence tomography and Scheimpflug imaging in keratoconus
    • 22261325
    • Szalai E, Berta A, Hassan Z, Módis L. Reliability and repeatability of swept-source Fourier-domain optical coherence tomography and Scheimpflug imaging in keratoconus. J Cataract Refract Surg. 2012;38:485-94.
    • (2012) J Cataract Refract Surg , vol.38 , pp. 485-494
    • Szalai, E.1    Berta, A.2    Hassan, Z.3    Módis, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.