메뉴 건너뛰기




Volumn 86, Issue 8, 2012, Pages 4631-4643

Genetic evidence of a long-range RNA-RNA Interaction between the genomic 5' untranslated region and the nonstructural protein 1 coding region in murine and bovine coronaviruses

Author keywords

[No Author keywords available]

Indexed keywords

NONSTRUCTURAL PROTEIN 1; VIRUS RNA;

EID: 84861413619     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.06265-11     Document Type: Article
Times cited : (26)

References (56)
  • 2
    • 42449139748 scopus 로고    scopus 로고
    • Coronavirus infection modulates the unfolded protein response and mediates sustained translational repression
    • Bechill J, Chen Z, Brewer JW, Baker SC. 2008. Coronavirus infection modulates the unfolded protein response and mediates sustained translational repression. J. Virol. 82:4492-4501.
    • (2008) J. Virol. , vol.82 , pp. 4492-4501
    • Bechill, J.1    Chen, Z.2    Brewer, J.W.3    Baker, S.C.4
  • 4
    • 0031441843 scopus 로고    scopus 로고
    • Recombination and coronavirus defective interfering RNAs
    • Brian DA, Spaan WJM. 1997. Recombination and coronavirus defective interfering RNAs. Semin. Virol. 8:101-111.
    • (1997) Semin. Virol. , vol.8 , pp. 101-111
    • Brian, D.A.1    Spaan, W.J.M.2
  • 5
    • 24944485104 scopus 로고    scopus 로고
    • Mutagenesis of the murine hepatitis virus nsp1-coding region identifies residues important for protein processing, viral RNA synthesis, and viral replication
    • Brockway SM, Denison MR. 2005. Mutagenesis of the murine hepatitis virus nsp1-coding region identifies residues important for protein processing, viral RNA synthesis, and viral replication. Virology 340: 209-223.
    • (2005) Virology , vol.340 , pp. 209-223
    • Brockway, S.M.1    Denison, M.R.2
  • 6
    • 6344221938 scopus 로고    scopus 로고
    • Intracellular localization and protein interactions of the gene 1 protein p28 during mouse hepatitis virus replication
    • Brockway SM, Lu XT, Peters TR, Dermody TS, Denison MR. 2004. Intracellular localization and protein interactions of the gene 1 protein p28 during mouse hepatitis virus replication. J. Virol. 78:11551-11562.
    • (2004) J. Virol. , vol.78 , pp. 11551-11562
    • Brockway, S.M.1    Lu, X.T.2    Peters, T.R.3    Dermody, T.S.4    Denison, M.R.5
  • 7
    • 34447280359 scopus 로고    scopus 로고
    • An RNA stem-loop within the bovine coronavirus nsp1 coding region is a cis-acting element in defective interfering RNA replication
    • Brown CG, Nixon KS, Senanayake SD, Brian DA. 2007. An RNA stem-loop within the bovine coronavirus nsp1 coding region is a cis-acting element in defective interfering RNA replication. J. Virol. 81:7716-7724.
    • (2007) J. Virol. , vol.81 , pp. 7716-7724
    • Brown, C.G.1    Nixon, K.S.2    Senanayake, S.D.3    Brian, D.A.4
  • 8
    • 0029872237 scopus 로고    scopus 로고
    • cis requirement for N-specific protein sequence in bovine coronavirus defective interfering RNA replication
    • Chang RY, Brian DA. 1996. cis requirement for N-specific protein sequence in bovine coronavirus defective interfering RNA replication. J. Virol. 70:2201-2207.
    • (1996) J. Virol. , vol.70 , pp. 2201-2207
    • Chang, R.Y.1    Brian, D.A.2
  • 9
    • 0027997834 scopus 로고
    • A cis-acting function for the coronavirus leader in defective interfering RNA replication
    • Chang RY, Hofmann MA, Sethna PB, Brian DA. 1994. A cis-acting function for the coronavirus leader in defective interfering RNA replication. J. Virol. 68:8223-8231.
    • (1994) J. Virol. , vol.68 , pp. 8223-8231
    • Chang, R.Y.1    Hofmann, M.A.2    Sethna, P.B.3    Brian, D.A.4
  • 10
    • 77950955247 scopus 로고    scopus 로고
    • Group-specific structural features of the 5'-proximal sequences of coronavirus genomic RNAs
    • Chen SC, Olsthoorn RC. 2010. Group-specific structural features of the 5'-proximal sequences of coronavirus genomic RNAs. Virology 401:29-41.
    • (2010) , vol.401 , pp. 29-41
    • Chen, S.C.1    Olsthoorn, R.C.2
  • 11
    • 0030023675 scopus 로고    scopus 로고
    • Molecular anatomy of mouse hepatitis virus persistence: coevolution of increased host cell resistance and virus virulence
    • Chen W, Baric RS. 1996. Molecular anatomy of mouse hepatitis virus persistence: coevolution of increased host cell resistance and virus virulence. J. Virol. 70:3947-3960.
    • (1996) J. Virol. , vol.70 , pp. 3947-3960
    • Chen, W.1    Baric, R.S.2
  • 12
    • 0031575512 scopus 로고    scopus 로고
    • Host-derived intracellular immunization against mouse hepatitis virus infection
    • Chen W, Madden VJ, Bagnell CR, Jr., Baric RS. 1997. Host-derived intracellular immunization against mouse hepatitis virus infection. Virology 228:318-332.
    • (1997) Virology , vol.228 , pp. 318-332
    • Chen, W.1    Madden, V.J.2    Bagnell Jr., C.R.3    Baric, R.S.4
  • 13
    • 62549159638 scopus 로고    scopus 로고
    • Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase
    • Chen Y, et al. 2009. Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase. Proc. Natl. Acad. Sci. U. S. A. 106:3484-3489.
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 318-3489
    • Chen, Y.1
  • 14
    • 47749138964 scopus 로고    scopus 로고
    • Coronavirus nonstructural protein 16 is a cap-0 binding enzyme possessing (nucleoside-2'O)-methyltransferase activity
    • Decroly E, et al. 2008. Coronavirus nonstructural protein 16 is a cap-0 binding enzyme possessing (nucleoside-2'O)-methyltransferase activity. J. Virol. 82:8071-8084.
    • (2008) J. Virol. , vol.82 , pp. 8071-8084
    • Decroly, E.1
  • 15
    • 84872261552 scopus 로고    scopus 로고
    • Proposal to divide the family Coronaviridae into subfamilies, Coronavirinae and Torovirinae, and rationalize the classification of species
    • de Groot RJ, Ziebuhr J, Poon LL, Woo PC, et al. 2008. Proposal to divide the family Coronaviridae into subfamilies, Coronavirinae and Torovirinae, and rationalize the classification of species. http://talk.ictvonline.org/files/ictv_official_taxonomy_updates_since_the_8th_report/m/vertebrate-2008 /1230.aspx.
    • (2008)
    • de Groot, R.J.1    Ziebuhr, J.2    Poon, L.L.3    Woo, P.C.4
  • 16
    • 0023153610 scopus 로고
    • Identification of putative polymerase gene product in cells infected with murine coronavirus A59
    • Denison M, Perlman S. 1987. Identification of putative polymerase gene product in cells infected with murine coronavirus A59. Virology 157:565-568.
    • (1987) Virology , vol.157 , pp. 565-568
    • Denison, M.1    Perlman, S.2
  • 17
    • 2442650226 scopus 로고    scopus 로고
    • Cleavage between replicase proteins p28 and p65 of mouse hepatitis virus is not required for virus replication
    • Denison MR, et al. 2004. Cleavage between replicase proteins p28 and p65 of mouse hepatitis virus is not required for virus replication. J. Virol. 78:5957-5965.
    • (2004) J. Virol. , vol.78 , pp. 5957-5965
    • Denison, M.R.1
  • 18
    • 0038758951 scopus 로고    scopus 로고
    • Transmissible gastroenteritis coronavirus packaging signal is located at the 5' end of the virus genome
    • Escors D, Izeta A, Capiscol C, Enjuanes L. 2003. Transmissible gastroenteritis coronavirus packaging signal is located at the 5' end of the virus genome. J. Virol. 77:7890-7902.
    • (2003) J. Virol. , vol.77 , pp. 7890-7902
    • Escors, D.1    Izeta, A.2    Capiscol, C.3    Enjuanes, L.4
  • 20
    • 33846503830 scopus 로고    scopus 로고
    • A hypervariable region within the 3' cis-acting element of the murine coronavirus genome is nonessential for RNA synthesis but affects pathogenesis
    • Goebel SJ, Miller TB, Bennett CJ, Bernard KA, Masters PS. 2007. A hypervariable region within the 3' cis-acting element of the murine coronavirus genome is nonessential for RNA synthesis but affects pathogenesis. J. Virol. 81:1274-1287.
    • (2007) J. Virol. , vol.81 , pp. 1274-1287
    • Goebel, S.J.1    Miller, T.B.2    Bennett, C.J.3    Bernard, K.A.4    Masters, P.S.5
  • 22
    • 79956143000 scopus 로고    scopus 로고
    • An optimal cis-replication stem-loop IV in the 5' untranslated region of the mouse coronavirus genome extends 16 nucleotides into open reading frame 1
    • Guan BJ, Wu HY, Brian DA. 2011. An optimal cis-replication stem-loop IV in the 5' untranslated region of the mouse coronavirus genome extends 16 nucleotides into open reading frame 1. J. Virol. 85:5593-5605.
    • (2011) J. Virol. , vol.85 , pp. 5593-5605
    • Guan, B.J.1    Wu, H.Y.2    Brian, D.A.3
  • 23
    • 66149109923 scopus 로고    scopus 로고
    • Bovine coronavirus nonstructural protein 1 (p28) is an RNA binding protein that binds terminal genomic cis-replication elements
    • Gustin KM, Guan BJ, Dziduszko A, Brian DA. 2009. Bovine coronavirus nonstructural protein 1 (p28) is an RNA binding protein that binds terminal genomic cis-replication elements. J. Virol. 83:6087-6097.
    • (2009) J. Virol. , vol.83 , pp. 6087-6097
    • Gustin, K.M.1    Guan, B.J.2    Dziduszko, A.3    Brian, D.A.4
  • 25
    • 0025150550 scopus 로고
    • Bovine coronavirus mRNA replication continues throughout persistent infection in cell culture
    • Hofmann MA, Sethna PB, Brian DA. 1990. Bovine coronavirus mRNA replication continues throughout persistent infection in cell culture. J. Virol. 64:4108-4114.
    • (1990) J. Virol. , vol.64 , pp. 4108-4114
    • Hofmann, M.A.1    Sethna, P.B.2    Brian, D.A.3
  • 26
    • 17144424622 scopus 로고    scopus 로고
    • Translational control in stress and apoptosis
    • Holcik M, Sonenberg N. 2005. Translational control in stress and apoptosis. Nat. Rev. Mol. Cell Biol. 6:318-327.
    • (2005) Nat. Rev. Mol. Cell Biol. , vol.6 , pp. 318-327
    • Holcik, M.1    Sonenberg, N.2
  • 27
    • 70350768988 scopus 로고    scopus 로고
    • A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 protein
    • Kamitani W, Huang C, Narayanan K, Lokugamage KG, Makino S. 2009. A two-pronged strategy to suppress host protein synthesis by SARS coronavirus Nsp1 protein. Nat. Struct. Mol. Biol. 16:1134-1140.
    • (2009) Nat. Struct. Mol. Biol. , vol.16 , pp. 1134-1140
    • Kamitani, W.1    Huang, C.2    Narayanan, K.3    Lokugamage, K.G.4    Makino, S.5
  • 28
    • 33748046163 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome coronavirus nsp1 protein suppresses host gene expression by promoting host mRNA degradation
    • Kamitani W, et al. 2006. Severe acute respiratory syndrome coronavirus nsp1 protein suppresses host gene expression by promoting host mRNA degradation. Proc. Natl. Acad. Sci. U. S. A. 103:12885-12890.
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 12885-12890
    • Kamitani, W.1
  • 29
    • 33750322376 scopus 로고    scopus 로고
    • Putative cis-acting stem-loops in the 5' untranslated region of the severe acute respiratory syndrome coronavirus can substitute for their mouse hepatitis virus counterparts
    • Kang H, Feng M, Schroeder ME, Giedroc DP, Leibowitz JL. 2006. Putative cis-acting stem-loops in the 5' untranslated region of the severe acute respiratory syndrome coronavirus can substitute for their mouse hepatitis virus counterparts. J. Virol. 80:10600-10614.
    • (2006) J. Virol. , vol.80 , pp. 10600-10614
    • Kang, H.1    Feng, M.2    Schroeder, M.E.3    Giedroc, D.P.4    Leibowitz, J.L.5
  • 30
    • 79551554217 scopus 로고    scopus 로고
    • Cellular IRES-mediated translation: the war of ITAFs in pathophysiological states
    • Komar AA, Hatzoglou M. 2011. Cellular IRES-mediated translation: the war of ITAFs in pathophysiological states. Cell Cycle 10:229-240.
    • (2011) Cell Cycle , vol.10 , pp. 229-240
    • Komar, A.A.1    Hatzoglou, M.2
  • 31
    • 0019503319 scopus 로고
    • Comparative analysis of RNA genomes of mouse hepatitis viruses
    • Lai MM, Stohlman SA. 1981. Comparative analysis of RNA genomes of mouse hepatitis viruses. J. Virol. 38:661-670.
    • (1981) J. Virol. , vol.38 , pp. 661-670
    • Lai, M.M.1    Stohlman, S.A.2
  • 32
    • 33845775710 scopus 로고    scopus 로고
    • Role for nonstructural protein 1 of severe acute respiratory syndrome coronavirus in chemokine dysregulation
    • Law AH, Lee DC, Cheung BK, Yim HC, Lau AS. 2007. Role for nonstructural protein 1 of severe acute respiratory syndrome coronavirus in chemokine dysregulation. J. Virol. 81:416-422.
    • (2007) J. Virol. , vol.81 , pp. 416-422
    • Law, A.H.1    Lee, D.C.2    Cheung, B.K.3    Yim, H.C.4    Lau, A.S.5
  • 33
    • 40649124715 scopus 로고    scopus 로고
    • Structural lability in stem-loop 1 drives a 5' UTR-3' UTR interaction in coronavirus replication
    • Li L, et al. 2008. Structural lability in stem-loop 1 drives a 5' UTR-3' UTR interaction in coronavirus replication. J. Mol. Biol. 377:790-803.
    • (2008) J. Mol. Biol. , vol.377 , pp. 790-803
    • Li, L.1
  • 34
    • 0031753727 scopus 로고    scopus 로고
    • Regulation of mRNA 1 expression by the 5'-untranslated region (5'-UTR) of the coronavirus infectious bronchitis virus (IBV)
    • Liu DX, Xu HY, Lim KP. 1998. Regulation of mRNA 1 expression by the 5'-untranslated region (5'-UTR) of the coronavirus infectious bronchitis virus (IBV). Adv. Exp. Med. Biol. 440:303-311.
    • (1998) Adv. Exp. Med. Biol. , vol.440 , pp. 303-311
    • Liu, D.X.1    Xu, H.Y.2    Lim, K.P.3
  • 35
    • 70450189452 scopus 로고    scopus 로고
    • Mouse hepatitis virus stem-loop 2 adopts a uYNMG(U)a-like tetraloop structure that is highly functionally tolerant of base substitutions
    • Liu P, et al. 2009. Mouse hepatitis virus stem-loop 2 adopts a uYNMG(U)a-like tetraloop structure that is highly functionally tolerant of base substitutions. J. Virol. 83:12084-12093.
    • (2009) J. Virol. , vol.83 , pp. 12084-12093
    • Liu, P.1
  • 37
    • 0024543970 scopus 로고
    • Evolution of the 5'-end of genomic RNA of murine coronaviruses during passages in vitro
    • Makino S, Lai MM. 1989. Evolution of the 5'-end of genomic RNA of murine coronaviruses during passages in vitro. Virology 169:227-232.
    • (1989) Virology , vol.169 , pp. 227-232
    • Makino, S.1    Lai, M.M.2
  • 38
    • 0033591465 scopus 로고    scopus 로고
    • Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure
    • Mathews DH, Sabina J, Zuker M, Turner DH. 1999. Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure. J. Mol. Biol. 288:911-940.
    • (1999) J. Mol. Biol. , vol.288 , pp. 911-940
    • Mathews, D.H.1    Sabina, J.2    Zuker, M.3    Turner, D.H.4
  • 39
    • 42449102158 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome coronavirus nsp1 suppresses host gene expression, including that of type I interferon, in infected cells
    • Narayanan K, et al. 2008. Severe acute respiratory syndrome coronavirus nsp1 suppresses host gene expression, including that of type I interferon, in infected cells. J. Virol. 82:4471-4479.
    • (2008) J. Virol. , vol.82 , pp. 4471-4479
    • Narayanan, K.1
  • 40
    • 34547883878 scopus 로고    scopus 로고
    • Mouse hepatitis coronavirus replication induces host translational shutoff and mRNAdecay, with concomitant formation of stress granules and processing bodies
    • Raaben M, Groot Koerkamp MJ, Rottier PJ, de Haan CA. 2007. Mouse hepatitis coronavirus replication induces host translational shutoff and mRNAdecay, with concomitant formation of stress granules and processing bodies. Cell Microbiol. 9:2218-2229.
    • (2007) Cell Microbiol , vol.9 , pp. 2218-2229
    • Raaben, M.1    Groot Koerkamp, M.J.2    Rottier, P.J.3    de Haan, C.A.4
  • 41
    • 0037942817 scopus 로고    scopus 로고
    • Stem-loop III in the 5' untranslated region is a cis-acting element in bovine coronavirus defective interfering RNA replication
    • Raman S, Bouma P, Williams GD, Brian DA. 2003. Stem-loop III in the 5' untranslated region is a cis-acting element in bovine coronavirus defective interfering RNA replication. J. Virol. 77:6720-6730.
    • (2003) J. Virol. , vol.77 , pp. 6720-6730
    • Raman, S.1    Bouma, P.2    Williams, G.D.3    Brian, D.A.4
  • 42
    • 25144448646 scopus 로고    scopus 로고
    • Stem-loop IV in the 5' untranslated region is a cis-acting element in bovine coronavirus defective interfering RNA replication
    • Raman S, Brian DA. 2005. Stem-loop IV in the 5' untranslated region is a cis-acting element in bovine coronavirus defective interfering RNA replication. J. Virol. 79:12434-12446.
    • (2005) J. Virol. , vol.79 , pp. 12434-12446
    • Raman, S.1    Brian, D.A.2
  • 43
    • 33845750075 scopus 로고    scopus 로고
    • A contemporary view of coronavirus transcription
    • Sawicki SG, Sawicki DL, Siddell SG. 2007. A contemporary view of coronavirus transcription. J. Virol. 81:20-29.
    • (2007) J. Virol. , vol.81 , pp. 20-29
    • Sawicki, S.G.1    Sawicki, D.L.2    Siddell, S.G.3
  • 44
    • 78649375395 scopus 로고    scopus 로고
    • Translational regulation of gene expression during conditions of cell stress
    • Spriggs KA, Bushell M, Willis AE. 2010. Translational regulation of gene expression during conditions of cell stress. Mol. Cell 40:228-237.
    • (2010) Mol. Cell , vol.40 , pp. 228-237
    • Spriggs, K.A.1    Bushell, M.2    Willis, A.E.3
  • 45
    • 0028022039 scopus 로고
    • Coronavirus translational regulation: leader affects mRNA efficiency
    • Tahara SM, et al. 1994. Coronavirus translational regulation: leader affects mRNA efficiency. Virology 202:621-630.
    • (1994) Virology , vol.202 , pp. 621-630
    • Tahara, S.M.1
  • 46
    • 77954668466 scopus 로고    scopus 로고
    • An RNA element at the 5'-end of the poliovirus genome functions as a general promoter for RNA synthesis
    • Vogt DA, Andino R. 2010. An RNA element at the 5'-end of the poliovirus genome functions as a general promoter for RNA synthesis. PLoS Pathog. 6:e1000936.
    • (2010) PLoS Pathog , vol.6
    • Vogt, D.A.1    Andino, R.2
  • 47
    • 35448939321 scopus 로고    scopus 로고
    • Severe acute respiratory syndrome coronavirus evades antiviral signaling: role of nsp1 and rational design of an attenuated strain
    • Wathelet MG, Orr M, Frieman MB, Baric RS. 2007. Severe acute respiratory syndrome coronavirus evades antiviral signaling: role of nsp1 and rational design of an attenuated strain. J. Virol. 81:11620-11633.
    • (2007) J. Virol. , vol.81 , pp. 11620-11633
    • Wathelet, M.G.1    Orr, M.2    Frieman, M.B.3    Baric, R.S.4
  • 48
    • 77955462625 scopus 로고    scopus 로고
    • Subgenomic messenger RNA amplification in coronaviruses
    • Wu HY, Brian DA. 2010. Subgenomic messenger RNA amplification in coronaviruses. Proc. Natl. Acad. Sci. U. S. A. 107:12257-12262.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 12257-12262
    • Wu, H.Y.1    Brian, D.A.2
  • 49
    • 33144476463 scopus 로고    scopus 로고
    • Bovine coronavirus 5'-proximal genomic acceptor hotspot for discontinuous transcription is 65 nucleotides wide
    • Wu HY, Ozdarendeli A, Brian DA. 2006. Bovine coronavirus 5'-proximal genomic acceptor hotspot for discontinuous transcription is 65 nucleotides wide. J. Virol. 80:2183-2193.
    • (2006) J. Virol. , vol.80 , pp. 2183-2193
    • Wu, H.Y.1    Ozdarendeli, A.2    Brian, D.A.3
  • 50
    • 80052282203 scopus 로고    scopus 로고
    • Mouse hepatitis virus stem-loop 4 functions as a spacer element required to drive subgenomic RNA synthesis
    • Yang D, Liu P, Giedroc DP, Leibowitz J. 2011. Mouse hepatitis virus stem-loop 4 functions as a spacer element required to drive subgenomic RNA synthesis. J. Virol. 85:9199-9209.
    • (2011) J. Virol. , vol.85 , pp. 9199-9209
    • Yang, D.1    Liu, P.2    Giedroc, D.P.3    Leibowitz, J.4
  • 51
    • 0025799395 scopus 로고
    • Heterogeneity of gene expression of the hemagglutinin-esterase (HE) protein of murine coronaviruses
    • Yokomori K, Banner LR, Lai MM. 1991. Heterogeneity of gene expression of the hemagglutinin-esterase (HE) protein of murine coronaviruses. Virology 183:647-657.
    • (1991) Virology , vol.183 , pp. 647-657
    • Yokomori, K.1    Banner, L.R.2    Lai, M.M.3
  • 52
    • 0036838992 scopus 로고    scopus 로고
    • Systematic assembly of a full-length infectious cDNA of mouse hepatitis virus strain A59
    • Yount B, Denison MR, Weiss SR, Baric RS. 2002. Systematic assembly of a full-length infectious cDNA of mouse hepatitis virus strain A59. J. Virol. 76:11065-11078.
    • (2002) J. Virol. , vol.76 , pp. 11065-11078
    • Yount, B.1    Denison, M.R.2    Weiss, S.R.3    Baric, R.S.4
  • 53
    • 0028086070 scopus 로고
    • Unusual heterogeneity of leader-mRNA fusion in a murine coronavirus: implications for the mechanism of RNA transcription and recombination
    • Zhang X, Lai MM. 1994. Unusual heterogeneity of leader-mRNA fusion in a murine coronavirus: implications for the mechanism of RNA transcription and recombination. J. Virol. 68:6626-6633.
    • (1994) J. Virol. , vol.68 , pp. 6626-6633
    • Zhang, X.1    Lai, M.M.2
  • 54
    • 0042121256 scopus 로고    scopus 로고
    • Mfold web server for nucleic acid folding and hybridization prediction
    • Zuker M. 2003. Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res. 31:3406-3415.
    • (2003) Nucleic Acids Res , vol.31 , pp. 3406-3415
    • Zuker, M.1
  • 55
    • 0347319103 scopus 로고    scopus 로고
    • Sequence motifs involved in the regulation of discontinuous coronavirus subgenomic RNA synthesis
    • Zuniga S, Sola I, Alonso S, Enjuanes L. 2004. Sequence motifs involved in the regulation of discontinuous coronavirus subgenomic RNA synthesis. J. Virol. 78:980-994.
    • (2004) J. Virol. , vol.78 , pp. 980-994
    • Zuniga, S.1    Sola, I.2    Alonso, S.3    Enjuanes, L.4
  • 56
    • 34548425017 scopus 로고    scopus 로고
    • Coronavirus non-structural protein 1 is a major pathogenicity factor: implications for the rational design of coronavirus vaccines
    • Zust R, et al. 2007. Coronavirus non-structural protein 1 is a major pathogenicity factor: implications for the rational design of coronavirus vaccines. PLoS Pathog. 3:e109.
    • (2007) PLoS Pathog , vol.3
    • Zust, R.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.