-
1
-
-
54549094903
-
Somatic mutations affect key pathways in lung adenocarcinoma
-
Ding L, Getz G, Wheeler DA, et al: Somatic mutations affect key pathways in lung adenocarcinoma. Nature 455:1069-1075, 2008
-
(2008)
Nature
, vol.455
, pp. 1069-1075
-
-
Ding, L.1
Getz, G.2
Wheeler, D.A.3
-
2
-
-
84866410479
-
Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing
-
Imielinski M, Berger AH, Hammerman PS, et al: Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing. Cell 150:1107-1120, 2012
-
(2012)
Cell
, vol.150
, pp. 1107-1120
-
-
Imielinski, M.1
Berger, A.H.2
Hammerman, P.S.3
-
3
-
-
84866894408
-
Comprehensive genomic characterization of squamous cell lung cancers
-
Cancer Genome Atlas Research Network
-
Cancer Genome Atlas Research Network: Comprehensive genomic characterization of squamous cell lung cancers. Nature 489:519-525, 2012
-
(2012)
Nature
, vol.489
, pp. 519-525
-
-
-
4
-
-
84866434919
-
Genomic landscape of non-small cell lung cancer in smokers and never-smokers
-
Govindan R, Ding L, Griffith M, et al: Genomic landscape of non-small cell lung cancer in smokers and never-smokers. Cell 150:1121-1134, 2012
-
(2012)
Cell
, vol.150
, pp. 1121-1134
-
-
Govindan, R.1
Ding, L.2
Griffith, M.3
-
5
-
-
84868309107
-
The transcriptional landscape and mutational profile of lung adenocarcinoma
-
Seo JS, Ju YS, Lee WC, et al: The transcriptional landscape and mutational profile of lung adenocarcinoma. Genome Res 22:2109-2119, 2012
-
(2012)
Genome Res
, vol.22
, pp. 2109-2119
-
-
Seo, J.S.1
Ju, Y.S.2
Lee, W.C.3
-
6
-
-
84905029258
-
Comprehensive molecular profiling of lung adenocarcinoma
-
Cancer Genome Atlas Research Network
-
Cancer Genome Atlas Research Network: Comprehensive molecular profiling of lung adenocarcinoma. Nature 511:543-550, 2014
-
(2014)
Nature
, vol.511
, pp. 543-550
-
-
-
7
-
-
19844375720
-
Epidermal growth factor receptor mutations in non-small-cell lung cancer: Implications for treatment and tumor biology
-
Jänne PA, Engelman JA, Johnson BE: Epidermal growth factor receptor mutations in non-small-cell lung cancer: Implications for treatment and tumor biology. J Clin Oncol 23:3227-3234, 2005
-
(2005)
J Clin Oncol
, vol.23
, pp. 3227-3234
-
-
Jänne, P.A.1
Engelman, J.A.2
Johnson, B.E.3
-
8
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R, et al: Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med 350:2129-2139, 2004
-
(2004)
N Engl J Med
, vol.350
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
9
-
-
20444498630
-
Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer
-
Cappuzzo F, Hirsch FR, Rossi E, et al: Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer. J Natl Cancer Inst 97:643-655, 2005
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 643-655
-
-
Cappuzzo, F.1
Hirsch, F.R.2
Rossi, E.3
-
10
-
-
69949186250
-
Screening for epidermal growth factor receptor mutations in lung cancer
-
Rosell R, Moran T, Queralt C, et al: Screening for epidermal growth factor receptor mutations in lung cancer. N Engl J Med 361:958-967, 2009
-
(2009)
N Engl J Med
, vol.361
, pp. 958-967
-
-
Rosell, R.1
Moran, T.2
Queralt, C.3
-
11
-
-
84893353535
-
A prospective, molecular epidemiology study of EGFR mutations in Asian patients with advanced non-small-cell lung cancer of adenocarcinoma histology (PIONEER)
-
Shi Y, Au JS, Thongprasert S, et al: A prospective, molecular epidemiology study of EGFR mutations in Asian patients with advanced non-small-cell lung cancer of adenocarcinoma histology (PIONEER). J Thorac Oncol 9:154-162, 2014
-
(2014)
J Thorac Oncol
, vol.9
, pp. 154-162
-
-
Shi, Y.1
Au, J.S.2
Thongprasert, S.3
-
12
-
-
84881664448
-
Frequency of EGFR and KRAS mutations in patients with non small cell lung cancer by racial background: Do disparities exist?
-
Bauml J, Mick R, Zhang Y, et al: Frequency of EGFR and KRAS mutations in patients with non small cell lung cancer by racial background: Do disparities exist? Lung Cancer 81:347-353, 2013
-
(2013)
Lung Cancer
, vol.81
, pp. 347-353
-
-
Bauml, J.1
Mick, R.2
Zhang, Y.3
-
13
-
-
84884413518
-
Smoking status and self-reported race affect the frequency of clinically relevant oncogenic alterations in non-small-cell lung cancers at a United States-based academic medical practice
-
Yamaguchi N, Vanderlaan PA, Folch E, et al: Smoking status and self-reported race affect the frequency of clinically relevant oncogenic alterations in non-small-cell lung cancers at a United States-based academic medical practice. Lung Cancer 82:31-37, 2013
-
(2013)
Lung Cancer
, vol.82
, pp. 31-37
-
-
Yamaguchi, N.1
Vanderlaan, P.A.2
Folch, E.3
-
14
-
-
84920278292
-
-
US Census Bureau
-
US Census Bureau: The Black Population: 2010. http://www.census.gov/prod/cen2010/briefs/c2010br-06.pdf
-
(2010)
The Black Population
-
-
-
15
-
-
1942472485
-
Cancer disparities by race/ethnicity and socioeconomic status
-
Ward E, Jemal A, Cokkinides V, et al: Cancer disparities by race/ethnicity and socioeconomic status. CA Cancer J Clin 54:78-93, 2004
-
(2004)
CA Cancer J Clin
, vol.54
, pp. 78-93
-
-
Ward, E.1
Jemal, A.2
Cokkinides, V.3
-
16
-
-
84877257060
-
Cancer statistics for African Americans, 2013
-
DeSantis C, Naishadham D, Jemal A: Cancer statistics for African Americans, 2013. CA Cancer J Clin 63:151-166, 2013
-
(2013)
CA Cancer J Clin
, vol.63
, pp. 151-166
-
-
DeSantis, C.1
Naishadham, D.2
Jemal, A.3
-
17
-
-
84904855517
-
Erlotinib in African Americans with advanced non-small cell lung cancer: A prospective randomized study with genetic and pharmacokinetic analyses
-
Phelps MA, Stinchcombe TE, Blachly JS, et al: Erlotinib in African Americans with advanced non-small cell lung cancer: A prospective randomized study with genetic and pharmacokinetic analyses. Clin Pharmacol Ther 96:182-191, 2014
-
(2014)
Clin Pharmacol Ther
, vol.96
, pp. 182-191
-
-
Phelps, M.A.1
Stinchcombe, T.E.2
Blachly, J.S.3
-
18
-
-
76249114566
-
Characterizing the admixed African ancestry of African Americans
-
Zakharia F, Basu A, Absher D, et al: Characterizing the admixed African ancestry of African Americans. Genome Biol 10:R141, 2009
-
(2009)
Genome Biol
, vol.10
, pp. R141
-
-
Zakharia, F.1
Basu, A.2
Absher, D.3
-
19
-
-
33744459262
-
Racial admixture and its impact on BMI and blood pressure in African and Mexican Americans
-
Tang H, Jorgenson E, Gadde M, et al: Racial admixture and its impact on BMI and blood pressure in African and Mexican Americans. Hum Genet 119:624-633, 2006
-
(2006)
Hum Genet
, vol.119
, pp. 624-633
-
-
Tang, H.1
Jorgenson, E.2
Gadde, M.3
-
20
-
-
53349095856
-
Comparing genetic ancestry and self-described race in African Americans born in the United States and in Africa
-
Yaeger R, Avila-Bront A, Abdul K, et al: Comparing genetic ancestry and self-described race in African Americans born in the United States and in Africa. Cancer Epidemiol Biomarkers Prev 17:1329-1338, 2008
-
(2008)
Cancer Epidemiol Biomarkers Prev
, vol.17
, pp. 1329-1338
-
-
Yaeger, R.1
Avila-Bront, A.2
Abdul, K.3
-
21
-
-
33745591590
-
The genetic structure of human populations studied through short insertion-deletion polymorphisms
-
Bastos-Rodrigues L, Pimenta JR, Pena SD: The genetic structure of human populations studied through short insertion-deletion polymorphisms. Ann Hum Genet 70:658-665, 2006
-
(2006)
Ann Hum Genet
, vol.70
, pp. 658-665
-
-
Bastos-Rodrigues, L.1
Pimenta, J.R.2
Pena, S.D.3
-
23
-
-
75549087826
-
COSMIC (the Catalogue of Somatic Mutations in Cancer): A resource to investigate acquired mutations in human cancer
-
Forbes SA, Tang G, Bindal N, et al: COSMIC (the Catalogue of Somatic Mutations in Cancer): A resource to investigate acquired mutations in human cancer. Nucleic Acids Res 38:D652-D657, 2010
-
(2010)
Nucleic Acids Res
, vol.38
, pp. D652-D657
-
-
Forbes, S.A.1
Tang, G.2
Bindal, N.3
-
24
-
-
0034118493
-
Inference of population structure using multilocus genotype data
-
Pritchard JK, Stephens M, Donnelly P: Inference of population structure using multilocus genotype data. Genetics 155:945-959, 2000
-
(2000)
Genetics
, vol.155
, pp. 945-959
-
-
Pritchard, J.K.1
Stephens, M.2
Donnelly, P.3
-
25
-
-
84880449591
-
Lessons learned from lung cancer genomics: The emerging concept of individualized diagnostics and treatment
-
Buettner R, Wolf J, Thomas RK: Lessons learned from lung cancer genomics: The emerging concept of individualized diagnostics and treatment. J Clin Oncol 31:1858-1865, 2013
-
(2013)
J Clin Oncol
, vol.31
, pp. 1858-1865
-
-
Buettner, R.1
Wolf, J.2
Thomas, R.K.3
-
26
-
-
79951475133
-
A decade's perspective on DNA sequencing technology
-
Mardis ER: A decade's perspective on DNA sequencing technology. Nature 470:198-203, 2011
-
(2011)
Nature
, vol.470
, pp. 198-203
-
-
Mardis, E.R.1
-
27
-
-
84863393678
-
Cancer genomics: Technology, discovery, and translation
-
Tran B, Dancey JE, Kamel-Reid S, et al: Cancer genomics: Technology, discovery, and translation. J Clin Oncol 30:647-660, 2012
-
(2012)
J Clin Oncol
, vol.30
, pp. 647-660
-
-
Tran, B.1
Dancey, J.E.2
Kamel-Reid, S.3
-
28
-
-
77954566882
-
Rapid targeted mutational analysis of human tumours: A clinical platform to guide personalized cancer medicine
-
Dias-Santagata D, Akhavanfard S, David SS, et al: Rapid targeted mutational analysis of human tumours: A clinical platform to guide personalized cancer medicine. EMBO Mol Med 2:146-158, 2010
-
(2010)
EMBO Mol Med
, vol.2
, pp. 146-158
-
-
Dias-Santagata, D.1
Akhavanfard, S.2
David, S.S.3
-
29
-
-
70849116358
-
Profiling critical cancer gene mutations in clinical tumor samples
-
MacConaill LE, Campbell CD, Kehoe SM, et al: Profiling critical cancer gene mutations in clinical tumor samples. PLoS One 4:e7887, 2009
-
(2009)
PLoS One
, vol.4
-
-
MacConaill, L.E.1
Campbell, C.D.2
Kehoe, S.M.3
-
30
-
-
79951761631
-
Frequency and type of epidermal growth factor receptor mutations in African Americans with non-small cell lung cancer
-
Cote ML, Haddad R, Edwards DJ, et al: Frequency and type of epidermal growth factor receptor mutations in African Americans with non-small cell lung cancer. J Thorac Oncol 6:627-630, 2011
-
(2011)
J Thorac Oncol
, vol.6
, pp. 627-630
-
-
Cote, M.L.1
Haddad, R.2
Edwards, D.J.3
-
31
-
-
73949154122
-
Genetic abnormalities of the EGFR pathway in African American patients with non-small-cell lung cancer
-
Leidner RS, Fu P, Clifford B, et al: Genetic abnormalities of the EGFR pathway in African American patients with non-small-cell lung cancer. J Clin Oncol 27:5620-5626, 2009
-
(2009)
J Clin Oncol
, vol.27
, pp. 5620-5626
-
-
Leidner, R.S.1
Fu, P.2
Clifford, B.3
-
32
-
-
20144387591
-
Mutations in the tyrosine kinase domain of the epidermal growth factor receptor in non-small cell lung cancer
-
Yang SH, Mechanic LE, Yang P, et al: Mutations in the tyrosine kinase domain of the epidermal growth factor receptor in non-small cell lung cancer. Clin Cancer Res 11:2106-2110, 2005
-
(2005)
Clin Cancer Res
, vol.11
, pp. 2106-2110
-
-
Yang, S.H.1
Mechanic, L.E.2
Yang, P.3
-
33
-
-
70349443680
-
Ethnic differences and functional analysis of MET mutations in lung cancer
-
Krishnaswamy S, Kanteti R, Duke-Cohan JS, et al: Ethnic differences and functional analysis of MET mutations in lung cancer. Clin Cancer Res 15:5714-5723, 2009
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5714-5723
-
-
Krishnaswamy, S.1
Kanteti, R.2
Duke-Cohan, J.S.3
-
34
-
-
78651087933
-
Frequency of EGFR and KRAS mutations in lung adenocarcinomas in African Americans
-
Reinersman JM, Johnson ML, Riely GJ, et al: Frequency of EGFR and KRAS mutations in lung adenocarcinomas in African Americans. J Thorac Oncol 6:28-31, 2011
-
(2011)
J Thorac Oncol
, vol.6
, pp. 28-31
-
-
Reinersman, J.M.1
Johnson, M.L.2
Riely, G.J.3
-
36
-
-
78650451788
-
Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer
-
Weiss J, Sos ML, Seidel D, et al: Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer. Sci Transl Med 2:62ra93, 2010
-
(2010)
Sci Transl Med
, vol.2
, pp. 62ra93
-
-
Weiss, J.1
Sos, M.L.2
Seidel, D.3
-
37
-
-
84872868948
-
ARID1A mutations in cancer: Another epigenetic tumor suppressor?
-
Wu JN, Roberts CW: ARID1A mutations in cancer: Another epigenetic tumor suppressor? Cancer Discov 3:35-43, 2013
-
(2013)
Cancer Discov
, vol.3
, pp. 35-43
-
-
Wu, J.N.1
Roberts, C.W.2
-
38
-
-
84896898658
-
Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers
-
Hoffman GR, Rahal R, Buxton F, et al: Functional epigenetics approach identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers. Proc Natl Acad Sci USA111:3128-3133, 2014
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 3128-3133
-
-
Hoffman, G.R.1
Rahal, R.2
Buxton, F.3
-
39
-
-
76049106059
-
Germline nonsense mutation and somatic inactivation of SMARCA4/BRG1 in a family with rhabdoid tumor predisposition syndrome
-
Schneppenheim R, Frühwald MC, Gesk S, et al: Germline nonsense mutation and somatic inactivation of SMARCA4/BRG1 in a family with rhabdoid tumor predisposition syndrome. Am J Hum Genet 86:279-284, 2010
-
(2010)
Am J Hum Genet
, vol.86
, pp. 279-284
-
-
Schneppenheim, R.1
Frühwald, M.C.2
Gesk, S.3
-
40
-
-
84899644463
-
Germline and somatic SMARCA4 mutations characterize small cell carcinoma of the ovary, hypercalcemic type
-
Witkowski L, Carrot-Zhang J, Albrecht S, et al: Germline and somatic SMARCA4 mutations characterize small cell carcinoma of the ovary, hypercalcemic type. Nat Genet 46:438-443, 2014
-
(2014)
Nat Genet
, vol.46
, pp. 438-443
-
-
Witkowski, L.1
Carrot-Zhang, J.2
Albrecht, S.3
-
41
-
-
84899635480
-
Recurrent SMARCA4 mutations in small cell carcinoma of the ovary
-
Jelinic P, Mueller JJ, Olvera N, et al: Recurrent SMARCA4 mutations in small cell carcinoma of the ovary. Nat Genet 46:424-426, 2014
-
(2014)
Nat Genet
, vol.46
, pp. 424-426
-
-
Jelinic, P.1
Mueller, J.J.2
Olvera, N.3
-
43
-
-
3042851775
-
Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer
-
Fukuoka J, Fujii T, Shih JH, et al: Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer. Clin Cancer Res 10:4314-4324, 2004
-
(2004)
Clin Cancer Res
, vol.10
, pp. 4314-4324
-
-
Fukuoka, J.1
Fujii, T.2
Shih, J.H.3
-
44
-
-
84907048311
-
A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1: Letter
-
Thompson KW, Marquez SB, Reisman D: A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1: Letter. Cancer Res 74:4946-4947, 2014
-
(2014)
Cancer Res
, vol.74
, pp. 4946-4947
-
-
Thompson, K.W.1
Marquez, S.B.2
Reisman, D.3
-
45
-
-
84883467670
-
A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1
-
Oike T, Ogiwara H, Tominaga Y, et al: A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1. Cancer Res 73:5508-5518, 2013
-
(2013)
Cancer Res
, vol.73
, pp. 5508-5518
-
-
Oike, T.1
Ogiwara, H.2
Tominaga, Y.3
-
46
-
-
84896126029
-
ARID1B is a specific vulnerability in ARID1A-mutant cancers
-
Helming KC, Wang X, Wilson BG, et al: ARID1B is a specific vulnerability in ARID1A-mutant cancers. Nat Med 20:251-254, 2014
-
(2014)
Nat Med
, vol.20
, pp. 251-254
-
-
Helming, K.C.1
Wang, X.2
Wilson, B.G.3
|