Recent progress on small vessel disease with cognitive impairment

International Journal of Clinical and Experimental Medicine

Volumn 8, Issue 5, 2015, Pages 7701-7709

  Gong, Li ^a   Liu, Xue Yuan ^a   Fang, Min ^a  

^a TONGJI UNIVERSITY   (China)

Author keywords

Biomarkers; Cognitive impairment; Molecular mechanism; Treatments; Vascular dementia

Indexed keywords

APOLIPOPROTEIN E; C REACTIVE PROTEIN; INTERLEUKIN 6; MICRORNA; NEOPTERIN; NIMODIPINE; NOTCH3 RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BLOOD BRAIN BARRIER; BRAIN HEMORRHAGE; BRAIN INFARCTION; CEREBROVASCULAR DISEASE; CLINICAL FEATURE; COGNITIVE DEFECT; COMORBIDITY; COMPUTER ASSISTED TOMOGRAPHY; DIFFUSION WEIGHTED IMAGING; DISEASE ASSOCIATION; HUMAN; MULTIINFARCT DEMENTIA; NERVOUS SYSTEM INFLAMMATION; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; WHITE MATTER LESION;

EID: 84937019579     PISSN: None     EISSN: 19405901     Source Type: Journal    
DOI: None     Document Type: Article

References (41)

1. [1] Pantoni L. Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges. Lancet Neurol 2010; 9: 689-701.
2. [2] Wardlaw JM, Smith C and Dichgans M. Mechanisms of sporadic cerebral small vessel disease: insights from neuroimaging. Lancet Neurol 2013; 12: 483-497.
3. [3] Patel B and Markus HS. Magnetic resonance imaging in cerebral small vessel disease and its use as a surrogate disease marker. Int J Stroke 2011; 6: 47-59.
4. [4] Fisher CM. The arterial lesions underlying lacunes. Acta Neuropathol 1969; 12: 1-15.
5. [5] Jackson CA, Hutchison A, Dennis MS, Wardlaw JM, Lindgren A, Norrving B, Anderson CS, Hankey GJ, Jamrozik K and Appelros P. Differing risk factor profiles of ischemic stroke subtypes evidence for a distinct lacunar arteriopathy? Stroke 2010; 41: 624-629.
6. [6] Vermeer SE, Longstreth WT Jr and Koudstaal PJ. Silent brain infarcts: a systematic review. Lancet Neurol 2007; 6: 611-619.
7. [7] Vermeer SE, Prins ND, den Heijer T, Hofman A, Koudstaal PJ and Breteler MM. Silent brain infarcts and the risk of dementia and cognitive decline. N Engl J Med 2003; 348: 1215-1222.
8. [8] Benisty S, Gouw AA, Porcher R, Madureira S, Hernandez K, Poggesi A, van der Flier WM, Van Straaten EC, Verdelho A and Ferro J. Location of lacunar infarcts correlates with cognition in a sample of non-disabled subjects with age-related white-matter changes: the LADIS study. J Neurol Neurosurg Psychiatry 2009; 80: 478-483.
9. [9] Wardlaw JM, Smith EE, Biessels GJ, Cordonnier C, Fazekas F, Frayne R, Lindley RI, O’Brien JT, Barkhof F and Benavente OR. Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration. Lancet Neurol 2013; 12: 822-838.
10. [10] Maillard P, Fletcher E, Harvey D, Carmichael O, Reed B, Mungas D and DeCarli C. White matter hyperintensity penumbra. Stroke 2011; 42: 1917-1922.
11. [11] Van Swieten JC, Staal S, Kappelle LJ, Derix MM and Van Gijn J. Are white matter lesions directly associated with cognitive impairment in patients with lacunar infarcts? J Neurol 1996; 243: 196-200.
12. [12] Pantoni L, Poggesi A and Inzitari D. The relation between white-matter lesions and cognition. Curr Opin Neurol 2007; 20: 390-397.
13. [13] Debette S and Markus HS. The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis. BMJ 2010; 341: c3666.
14. [14] Greenberg SM, Vernooij MW, Cordonnier C, Viswanathan A, Al-Shahi Salman R, Warach S, Launer LJ, Van Buchem MA and Breteler M. Cerebral microbleeds: a guide to detection and interpretation. Lancet Neurol 2009; 8: 165-174.
15. [15] Viswanathan A, Godin O, Jouvent E, O’Sullivan M, Gschwendtner A, Peters N, Duering M, Guichard JP, Holtmannspötter M and Dufouil C. Impact of MRI markers in subcortical vascular dementia: a multi-modal analysis in CADASIL. Neurobiol Aging 2010; 31: 1629-1636.
16. [16] Hilal S, Saini M, Tan CS, Catindig JA, Koay WI, Niessen WJ, Vrooman HA, Wong TY, Chen C and Ikram MK. Cerebral microbleeds and cognition: the epidemiology of dementia in singapore study. Alzheimer Dis Assoc Disord 2014; 28: 106-112.
17. [17] Shams S, Martola J, Granberg T, Li X, Shams M, Fereshtehnejad SM, Cavallin L, Aspelin P, Kristoffersen-Wiberg M and Wahlund LO. Cerebral Microbleeds: Different Prevalence, Topography, and Risk Factors Depending on Dementia Diagnosis-The Karolinska Imaging Dementia Study. AJNR Am J Neuroradiol 2015; 36: 661-6.
18. [18] Werring DJ, Gregoire SM and Cipolotti L. Cerebral microbleeds and vascular cognitive impairment. J Neurol Sci 2010; 299: 131-135.
19. [19] Hennerici MG. What are the mechanisms for post-stroke dementia? Lancet Neurol 2009; 8: 973-975.
20. [20] Pettersen JA, Sathiyamoorthy G, Gao FQ, Szilagyi G, Nadkarni NK, St George-Hyslop P, Rogaeva E and Black SE. Microbleed topography, leukoaraiosis, and cognition in probable Alzheimer disease from the Sunnybrook dementia study. Arch Neurol 2008; 65: 790-795.
21. [21] Iadecola C, Park L and Capone C. Threats to the mind aging, amyloid, and hypertension. Stroke 2009; 40: S40-S44.
22. [22] Charidimou A and Werring DJ. Cerebral microbleeds and cognition in cerebrovascular disease: an update. J Neurol Sci 2012; 322: 50-55.
23. [23] Baune BT, Roesler A, Knecht S and Berger K. Single and combined effects of cerebral white matter lesions and lacunar infarctions on cognitive function in an elderly population. J Gerontol A Biol Sci Med Sci 2009; 64: 118-24.
24. [24] Jokinen H, Kalska H, Ylikoski R, Madureira S, Verdelho A, Gouw A, Scheltens P, Barkhof F, Visser MC and Fazekas F. MRI-defined subcortical ischemic vascular disease: baseline clinical and neuropsychological findings. Cere-brovasc Dis 2009; 27: 336-344.
25. [25] Huijts M, Duits A, Van Oostenbrugge RJ, Kroon AA, De Leeuw PW and Staals J. Accumulation of MRI markers of cerebral small vessel disease is associated with decreased cognitive function. A study in first-ever lacunar stroke and hypertensive patients. Front Aging Neurosci 2013; 5: 72.
26. [26] Charlton RA, Schiavone F, Barrick TR, Morris RG and Markus HS. Diffusion tensor imaging detects age related white matter change over a 2 year follow-up which is associated with working memory decline. J Neurol Neurosurg Psychiatry 2010; 81: 13-19.
27. [27] Nitkunan A, Barrick TR, Charlton RA, Clark CA and Markus HS. Multimodal MRI in cerebral small vessel disease its relationship with cognition and sensitivity to change over time. Stroke 2008; 39: 1999-2005.
28. [28] Lawrence AJ, Patel B, Morris RG, MacKinnon AD, Rich PM, Barrick TR and Markus HS. Mechanisms of cognitive impairment in cerebral small vessel disease: multimodal MRI results from the St George’s Cognition and Neuroimaging in Stroke (SCANS) study. PLoS One 2013; 8: e61014.
29. [29] Lin CJ, Tu PC, Chern CM, Hsiao FJ, Chang FC, Cheng HL, Tang CW, Lee YC, Chen WT and Lee IH. Connectivity features for identifying cognitive impairment in presymptomatic carotid stenosis. PLoS One 2014; 9: e85441.
30. [30] Yang Y and Rosenberg GA. Blood-brain barrier breakdown in acute and chronic cerebrovascular disease. Stroke 2011; 42: 3323-3328.
31. [31] Wardlaw JM, Doubal FN, Valdes-Hernandez M, Wang X, Chappell FM, Shuler K, Armitage PA, Carpenter TC and Dennis MS. Blood-brain barrier permeability and long-term clinical and imaging outcomes in cerebral small vessel disease. Stroke 2013; 44: 525-527.
32. [32] Rosenberg GA. Neurological diseases in relation to the blood-brain barrier. J Cereb Blood Flow Metab 2012; 32: 1139-1151.
33. [33] Wiseman S, Marlborough F, Doubal F, Webb DJ and Wardlaw J. Blood markers of coagulation, fibrinolysis, endothelial dysfunction and inflammation in lacunar stroke versus non-lacunar stroke and non-stroke: systematic review and meta-analysis. Cerebrovasc Dis 2013; 37: 64-75.
34. [34] Aribisala BS, Wiseman S, Morris Z, Valdés-Hernández MC, Royle NA, Maniega SM, Gow AJ, Corley J, Bastin ME and Starr J. Circulating inflammatory markers are associated with magnetic resonance imaging-visible perivascular spaces but not directly with white matter hyperintensities. Stroke 2014; 45: 605-607.
35. [35] Rouhl RP, Damoiseaux JG, Lodder J, Theunissen RO, Knottnerus IL, Staals J, Henskens LH, Kroon AA, de Leeuw PW and Tervaert JW. Vascular inflammation in cerebral small vessel disease. Neurobiol Aging 2012; 33: 1800-1806.
36. [36] Friedman RC, Farh KK, Burge CB and Bartel DP. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res 2009; 19: 92-105.
37. [37] Fineberg SK, Kosik KS and Davidson BL. MicroRNAs potentiate neural development. Neuron 2009; 64: 303-309.
38. [38] Yan H, Fang M and Liu XY. Role of microRNAs in stroke and poststroke depression. Sci World J 2013; 2013: 459692.
39. [39] Hunter MP, Ismail N, Zhang X, Aguda BD, Lee EJ, Yu L, Xiao T, Schafer J, Lee ML and Schmittgen TD. Detection of microRNA expression in human peripheral blood microvesicles. PLoS One 2008; 3: e3694.
40. [40] Benavente OR, White CL, Pearce L, Pergola P, Roldan A, Benavente MF, Coffey C, McClure LA, Szychowski JM and Conwit R. The secondary prevention of small subcortical strokes (SPS3) study. Int J Stroke 2011; 6: 164-175.
41. [41] Dichgans M and Zietemann V. Prevention of vascular cognitive impairment. Stroke 2012; 43: 3137-3146.