Dietary obacunone supplementation stimulates muscle hypertrophy, and suppresses hyperglycemia and obesity through the TGR5 and PPARγ pathway

Biochemical and Biophysical Research Communications

Volumn 463, Issue 4, 2015, Pages 846-852

  Horiba, Taro ^a   Katsukawa, Masahiro ^a   Mita, Moeko ^b   Sato, Ryuichiro ^b  

^a KIKKOMAN CORPORATION   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Hyperglycemia; Hypertrophy; Obacunone; Obesity; PPAR ; TGR5

Indexed keywords

G PROTEIN COUPLED BILE ACID RECEPTOR; G PROTEIN COUPLED RECEPTOR; GLUCAGON LIKE PEPTIDE 1; GLUCOSE; HEMOGLOBIN A1C; OBACUNONE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; UNCLASSIFIED DRUG; BENZOXEPIN DERIVATIVE; GPBAR1 PROTEIN, HUMAN; LIMONOID;

3T3 CELL LINE; ADIPOCYTE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIABETIC ACTIVITY; ARTICLE; BODY WEIGHT; CLINICAL FEATURE; COMPARATIVE STUDY; CONTROLLED STUDY; DIET SUPPLEMENTATION; FAT CONTENT; GASTROCNEMIUS MUSCLE; GLUCOSE BLOOD LEVEL; HEK293 CELL LINE; HEMOGLOBIN BLOOD LEVEL; HUMAN; HUMAN CELL; HYPERGLYCEMIA; LIPID STORAGE; LUCIFERASE ASSAY; MALE; METABOLIC REGULATION; MOUSE; MUSCLE HYPERTROPHY; NONHUMAN; OBESITY; PRIORITY JOURNAL; QUADRICEPS FEMORIS MUSCLE; THIN LAYER CHROMATOGRAPHY; TRANSCRIPTION INITIATION; WHITE ADIPOSE TISSUE; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; HYPERTROPHY; METABOLIC SYNDROME X; METABOLISM; SKELETAL MUSCLE;

CITRUS; MUS;

ANIMALS; BENZOXEPINS; DIETARY SUPPLEMENTS; HEK293 CELLS; HUMANS; HYPERGLYCEMIA; HYPERTROPHY; LIMONINS; METABOLIC SYNDROME X; MICE; MUSCLE, SKELETAL; OBESITY; PPAR GAMMA; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84936985103     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.06.022     Document Type: Article

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