Simultaneous exposure to multiple heavy metals and glyphosate may contribute to Sri Lankan agricultural nephropathy

BMC Nephrology

Volumn 16, Issue 1, 2015, Pages

  Jayasumana, Channa ^a   Gunatilake, Sarath ^b   Siribaddana, Sisira ^a  

^a UNIVERSITY OF COLOMBO   (Sri Lanka)

^b CALIFORNIA STATE UNIVERSITY   (United States)

Author keywords

Chronic kidney disease; Heavy metals; Pesticides; Sri Lanka; Synergistic effect

Indexed keywords

ALUMINUM; ANTIMONY; ARSENIC; BARIUM; CADMIUM; CHROMIUM; COBALT; COPPER; CREATININE; GLYPHOSATE; HEAVY METAL; IRON; LEAD; MANGANESE; MOLYBDENUM; NICKEL; SELENIUM; STRONTIUM; TIN; TITANIUM; VANADIUM; ZINC; GLYCINE; HERBICIDE;

ADULT; ARTICLE; CHRONIC KIDNEY DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; ENDEMIC DISEASE; FEMALE; HUMAN; MALE; MIDDLE AGED; NEPHROTOXICITY; PATHOGENESIS; SRI LANKA; SRI LANKAN AGRICULTURAL NEPHROPATHY; URINALYSIS; AGRICULTURAL WORKERS' DISEASES; ANALOGS AND DERIVATIVES; CASE CONTROL STUDY; NEPHRITIS, INTERSTITIAL; OCCUPATIONAL EXPOSURE; RENAL INSUFFICIENCY, CHRONIC; STATISTICS AND NUMERICAL DATA; URINE;

ADULT; AGRICULTURAL WORKERS' DISEASES; CASE-CONTROL STUDIES; ENDEMIC DISEASES; FEMALE; GLYCINE; HERBICIDES; HUMANS; MALE; METALS, HEAVY; MIDDLE AGED; NEPHRITIS, INTERSTITIAL; OCCUPATIONAL EXPOSURE; RENAL INSUFFICIENCY, CHRONIC; SRI LANKA;

EID: 84936935162     PISSN: None     EISSN: 14712369     Source Type: Journal    
DOI: 10.1186/s12882-015-0109-2     Document Type: Article

References (47)

1. Hogan CM. Heavy metal. The encyclopedia of earth. Available: http://www.eoearth.org/view/article/153463/. Accessed 30 March 2015.
2. Sharma B, Singh S, Siddiqi NJ. Biomedical implications of heavy metals induced imbalances in redox systems. Biomed Res Int. 2014;2014:640754. doi: 10.1155/2014/640754.
3. Kalia K, Flora SJS. Strategies for safe and effective therapeutic measures for chronic arsenic and lead poisoning. J Occup Health. 2005;47(1):1-21.
4. Bánfalvi G. Heavy Metals, Trace Elements and their Cellular Effects. In: Bánfalvi G, editor. Cellular Effects of Heavy Metals. Dordrecht: Springer; 2011. p. 3-28.
5. Pizzino G, Bitto A, Interdonato M, Galfo F, Irrera N, Mecchio A, et al. Oxidative stress and DNA repair and detoxification gene expression in adolescents exposed to heavy metals living in the Milazzo-Valle del Mela area (Sicily, Italy). Redox Biol. 2014;2:686-93.
6. Sabath E, Robles-Osorio ML. Renal health and the environment: heavy metal nephrotoxicity. Nefrologia. 2012;32:279-86.
7. Diamond GL, Zalups RK. Understanding Renal Toxicity of Heavy Metals. Toxicol Pathol. 1998;26:92-103.
8. Jayasumana MACS, Paranagama PA, Amarasinghe MD, Wijewardane KMRC, Dahanayake KS, Fonseka SI, et al. Possible link of Chronic arsenic toxicity with Chronic Kidney Disease of unknown etiology in Sri Lanka. J Nat Sci Res. 2013;64-73.
9. Nanayakkara S, Komiya T, Ratnatunga N, Senevirathna STMLD, Harada KH, Hitomi T, et al. Tubulointerstitial damage as the major pathological lesion in endemic chronic kidney disease among farmers in North Central Province of Sri Lanka. Environ Health Prev Med. 2012;17:213-21.
10. Athuraliya NT, Abeysekera TD, Amerasinghe PH, Kumarasiri R, Bandara P, Karunaratne U, et al. Uncertain etiologies of proteinuric-chronic kidney disease in rural Sri Lanka. Kidney Int. 2010;80:1212-21.
11. Wanigasuriya KP, Peiris-john RJ, Wickremasinghe R, Hittarage A. Chronic renal failure in North Central Province of Sri Lanka: an environmentally induced disease. Trans R Soc Trop Med Hygine. 2007;101:1013-7.
12. Herrera R, Orantes C, Almaguer M, Alfonso P, Bayarre HD, Leiva IM, et al. Clinical characteristics of chronic kidney disease of nontraditional causes in salvadoran farming communities. MEDICC Rev. 2014;16:39-48.
13. Jayasumana C, Gunatilake S, Senanayake P. Glyphosate, hard water and nephrotoxic metals: Are they the culprits behind the epidemic of chronic kidney disease of unknown etiology in Sri Lanka? Int J Environ Res Public Health. 2014;11:2125-47.
14. Wanigasuriya KP, Peiris-John RJ, Wickremasinghe R. Chronic kidney disease of unknown aetiology in Sri Lanka: is cadmium a likely cause? BMC Nephrol. 2011;12:32.
15. Jayatilake N, Mendis S, Maheepala P, Mehta FR. Chronic kidney disease of uncertain aetiology: prevalence and causative factors in a developing country. BMC Nephrol. 2013;14:180.
16. Nordberg GF. Historical Perspectives on Cadmium Toxicology. Toxicol Appl Pharmacol. 2009;238:192-200.
17. Mayo Clinic, Test Clinical and Interpretive. Available: http://www.mayomedicallaboratories.com/ test-catalog/Clinical + and + Interpretive/89889 Accessed 30 March 2015.
18. Cohen JW. Statistical Power Analysis for the Behavioral Sciences. 2nd ed. Hillsdale: Lawrence Erlbaum Associates; 1988.
19. Chandrajith R, Seneviratna S, Wickramaarachchi K, Attanayake T, Aturaliya TNC, Dissanayake CB. Natural radionuclides and trace elements in rice field soils in relation to fertilizer application: study of a chronic kidney disease area in Sri Lanka. Environ Earth Sci. 2009;60:193-201.
20. Jayasumana C, Fonseka S, Fernando A, Jayalath K, Amarasinghe M, Siribaddana S, et al. Phosphate fertilizer is a main source of arsenic in areas affected with chronic kidney disease of unknown etiology in Sri Lanka. Springer Plus. 2015;4:90.
21. Jayasumana C, Paranagama P, Fonseka S, Amarasinghe M, Gunatilake S, Siribaddana SH. Presence of Arsenic in Sri Lankan Rice. Int J Food Contamination. 2015;2:1.
22. Meharg AA, Norton G, Deacon C, Williams P, Adomako EE, Price A, et al. Variation in rice cadmium related to human exposure. Environ Sci Technol. 2013;47:5613-8.
23. Norton GJ, Williams PN, Adomako EE, Price AH, Zhu Y, Zhao F-J, et al. Lead in rice: Analysis of baseline lead levels in market and field collected rice grains. Sci Total Environ. 2014;485-486C:428-34.
24. Jayasumana C, Paranagama P, Agampodi S, Wijewardane C, Gunatilake S, Siribaddana S. Drinking well water and occupational exposure to Herbicides is associated with chronic kidney disease, in Padavi-Sripura, Sri Lanka. Environ Health. 2015;14:6.
25. Aprea C, Sciarra G, Lunghini L, Centi L, Ceccarelli F. Evaluation of respiratory and cutaneous doses and urinary excretion of alkylphosphates by workers in greenhouses treated with omethoate, fenitrothion, and tolclofos-methyl. AIHAJ. 2001;62:87-95.
26. Zheng LY, Umans JG, Tellez-Plaza M, Yeh F, Francesconi KA. Urine arsenic and prevalent albuminuria: Evidence from a population-based study. Am J Kidney Dis. 2013;61:385-94.
27. Hsueh YM, Chung CJ, Shiue HS, Chen JB, Chiang SS, Yang MH, et al. Urinary Arsenic Species and CKD in a Taiwanese Population: A Case-Control Study. Am J Kidney Dis. 2009;54:859-70.
28. Shi H, Shi X, Liu KJ. Oxidative Mechanism of Arsenic Toxicity and Carcinogenesis. Mol Cell Biochem. 2004;255:67-78.
29. Vyskocil A, Viau C, Cízková M. Chronic Nephrotoxicity of Soluble Nickel in Rats. Hum Exp Toxicol. 1994;13:689-93.
30. Loghman-Adham M. Renal Effects of Environmental and Occupational Lead Exposure. Environ Health Perspect. 1997;105:928-38.
31. De La Torre A, Granero S, Mayayo E, Corbella J, Domingo JL. Effect of age on vanadium nephrotoxicity in rats. Toxicol Lett. 1999;105:75-82.
32. Sahu BD, Koneru M, Bijargi SR, Kota A, Sistla R. Chromium-Induced Nephrotoxicity and Ameliorative Effect of Carvedilol in Rats: Involvement of Oxidative Stress, Apoptosis and Inflammation. Chem Biol Interact. 2014;223C:69-79.
33. Madden EF, Fowler BA. Mechanisms of nephrotoxicity from metal combinations: a review. Drug Chem Toxicol. 2000;23:1-12.
34. Stohs SJ, Bagchi D. Oxidative mechanisms in the toxicity of metal ions. Free Radic Biol Med. 1995;18:321-36.
35. Jiraungkoorskul W, Upatham ES, Kruatrachue M, Sahaphong S, Vichasri-Grams S, Pokethitiyook P. Biochemical and histopathological effects of glyphosate herbicide on nile tilapia (Oreochromis niloticus). Environ Toxicol. 2003;18:260-7.
36. Ayoola SO. Histopathological effect of glyphosate on Juvenile African Catfish(Clariasgariepinus). Am Eurasian J Agric Environ Sci. 2008;4:362-7.
37. Séralini GE, Cellier D, De Vendomois JS. New analysis of a rat feeding study with a genetically modified maize reveals signs of hepatorenal toxicity. Arch Environ Contam Toxicol. 2007;52:596-602.
38. Tizhe EV, Ibrahim ND, Fatihu MY, Igbokwe IO, George BD. Serum biochemical assessment of hepatic and renal functions of rats during oral exposure to glyphosate with zinc. Comp Clin Path 2013, 22. doi: 10.1007/s00580-013-1740-6
39. Larsen K, Najle R, Lifschitz A, Virkel G. Effects of sub-lethal exposure of rats to the herbicide glyphosate in drinking water: Glutathione transferase enzyme activities, levels of reduced glutathione and lipid peroxidation in liver, kidneys and small intestine. Environ Toxicol Pharmacol. 2012;34:811-8.
40. Krüger M, Schrödl W, Neuhaus J, Shehata AA. Field Investigations of Glyphosate in Urine of Danish Dairy Cows. J Environ Anal Toxicol. 2013;3:1000186.
41. ®). Interdiscip Toxicol. 2013;5:133-40.
42. Matos RC, Vieira C, Morais S, Pereira M de L, Pedrosa J. Nephrotoxicity effects of the wood preservative chromium copper arsenate on mice: Histopathological and quantitative approaches. J Trace Elem Med Biol. 2009;23:224-30.
43. Astiz M, de Alaniz MJT, Marra CA. Antioxidant defense system in rats simultaneously intoxicated with agrochemicals. Environ Toxicol Pharmacol. 2009;28:465-73.
44. Abdulla M, Chmielnicka J. New Aspects on the Distribution and Metabolism of Essential Trace Elements after Dietary Exposure to Toxic Metals. Biol Trace Elem Res. 1990;23:25-53.
45. Florea AM, Büsselberg D. Occurrence, Use and Potential Toxic Effects of Metals and Metal Compounds. Biometals. 2006;19:419-27.
46. Siriwardhana EARIE, Perera PAJ, Sivakanesan R, Abeysekara T, Nugegoda DB. Dehydration and malaria in augmenting the risk of developing chronic kidney disease in Sri Lanka. Indian J Nephrol. 2014;24:1-6.
47. Roncal Jimenez CA, Ishimoto T, Lanaspa MA, Rivard CJ, Nakagawa T, Ejaz AA, et al. Fructokinase activity mediates dehydration-induced renal injury. Kidney Int. 2014;86:294-302.