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Volumn 149, Issue 2, 2015, Pages 456-467.e15

Interleukin 6 increases production of cytokines by colonic innate lymphoid cells in mice and patients with chronic intestinal inflammation

Author keywords

CD; Immune Regulation; Innate Immunity; UC

Indexed keywords

BACTERIAL DNA; CD4 ANTIGEN; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 22; INTERLEUKIN 23; INTERLEUKIN 6; INTERLEUKIN 6 ANTIBODY; THY 1 ANTIGEN; TRANSCRIPTION FACTOR T BET; CD3 ANTIGEN; IL17A PROTEIN, HUMAN; INTERLEUKIN DERIVATIVE; INTERLEUKIN-22; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR;

EID: 84936890053     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2015.04.017     Document Type: Article
Times cited : (78)

References (43)
  • 1
    • 70949107842 scopus 로고    scopus 로고
    • Inflammatory bowel disease
    • C. Abraham, and J.H. Cho Inflammatory bowel disease N Engl J Med 361 2009 2066 2078
    • (2009) N Engl J Med , vol.361 , pp. 2066-2078
    • Abraham, C.1    Cho, J.H.2
  • 2
    • 83755219473 scopus 로고    scopus 로고
    • Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review
    • quiz e30 e42
    • N.A. Molodecky, I.S. Soon, D.M. Rabi, and et al. Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review Gastroenterology 142 2012 46 54 e42 quiz e30
    • (2012) Gastroenterology , vol.142 , pp. 46-54
    • Molodecky, N.A.1    Soon, I.S.2    Rabi, D.M.3
  • 3
    • 84868336049 scopus 로고    scopus 로고
    • Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
    • L. Jostins, S. Ripke, R.K. Weersma, and et al. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease Nature 491 2012 119 124
    • (2012) Nature , vol.491 , pp. 119-124
    • Jostins, L.1    Ripke, S.2    Weersma, R.K.3
  • 4
    • 57449118239 scopus 로고    scopus 로고
    • Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense
    • N. Satoh-Takayama, C.A. Vosshenrich, S. Lesjean-Pottier, and et al. Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense Immunity 29 2008 958 970
    • (2008) Immunity , vol.29 , pp. 958-970
    • Satoh-Takayama, N.1    Vosshenrich, C.A.2    Lesjean-Pottier, S.3
  • 5
    • 78751706261 scopus 로고    scopus 로고
    • CD4(+) lymphoid tissue-inducer cells promote innate immunity in the gut
    • G.F. Sonnenberg, L.A. Monticelli, M.M. Elloso, and et al. CD4(+) lymphoid tissue-inducer cells promote innate immunity in the gut Immunity 34 2011 122 134
    • (2011) Immunity , vol.34 , pp. 122-134
    • Sonnenberg, G.F.1    Monticelli, L.A.2    Elloso, M.M.3
  • 6
    • 77951878587 scopus 로고    scopus 로고
    • Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology
    • S. Buonocore, P.P. Ahern, H.H. Uhlig, and et al. Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology Nature 464 2010 1371 1375
    • (2010) Nature , vol.464 , pp. 1371-1375
    • Buonocore, S.1    Ahern, P.P.2    Uhlig, H.H.3
  • 7
    • 84867856710 scopus 로고    scopus 로고
    • The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells
    • N. Powell, A.W. Walker, E. Stolarczyk, and et al. The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells Immunity 37 2012 674 684
    • (2012) Immunity , vol.37 , pp. 674-684
    • Powell, N.1    Walker, A.W.2    Stolarczyk, E.3
  • 8
    • 60549102720 scopus 로고    scopus 로고
    • Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22
    • H. Takatori, Y. Kanno, W.T. Watford, and et al. Lymphoid tissue inducer-like cells are an innate source of IL-17 and IL-22 J Exp Med 206 2009 35 41
    • (2009) J Exp Med , vol.206 , pp. 35-41
    • Takatori, H.1    Kanno, Y.2    Watford, W.T.3
  • 9
    • 84872977452 scopus 로고    scopus 로고
    • Innate lymphoid cells - A proposal for uniform nomenclature
    • H. Spits, D. Artis, M. Colonna, and et al. Innate lymphoid cells - A proposal for uniform nomenclature Nat Rev Immunol 13 2013 145 149
    • (2013) Nat Rev Immunol , vol.13 , pp. 145-149
    • Spits, H.1    Artis, D.2    Colonna, M.3
  • 10
    • 34848889673 scopus 로고    scopus 로고
    • Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system
    • W.S. Garrett, G.M. Lord, S. Punit, and et al. Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system Cell 131 2007 33 45
    • (2007) Cell , vol.131 , pp. 33-45
    • Garrett, W.S.1    Lord, G.M.2    Punit, S.3
  • 11
    • 69249232549 scopus 로고    scopus 로고
    • Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells
    • W.S. Garrett, S. Punit, C.A. Gallini, and et al. Colitis-associated colorectal cancer driven by T-bet deficiency in dendritic cells Cancer Cell 16 2009 208 219
    • (2009) Cancer Cell , vol.16 , pp. 208-219
    • Garrett, W.S.1    Punit, S.2    Gallini, C.A.3
  • 12
    • 79958277385 scopus 로고    scopus 로고
    • IL-23-responsive innate lymphoid cells are increased in inflammatory bowel disease
    • A. Geremia, C.V. Arancibia-Carcamo, M.P. Fleming, and et al. IL-23-responsive innate lymphoid cells are increased in inflammatory bowel disease J Exp Med 208 2011 1127 1133
    • (2011) J Exp Med , vol.208 , pp. 1127-1133
    • Geremia, A.1    Arancibia-Carcamo, C.V.2    Fleming, M.P.3
  • 13
    • 85027945857 scopus 로고    scopus 로고
    • Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues
    • J.H. Bernink, C.P. Peters, M. Munneke, and et al. Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues Nat Immunol 14 2013 221 229
    • (2013) Nat Immunol , vol.14 , pp. 221-229
    • Bernink, J.H.1    Peters, C.P.2    Munneke, M.3
  • 14
    • 84876780238 scopus 로고    scopus 로고
    • Intraepithelial type 1 innate lymphoid cells are a unique subset of IL-12- and IL-15-responsive IFN-gamma-producing cells
    • A. Fuchs, W. Vermi, J.S. Lee, and et al. Intraepithelial type 1 innate lymphoid cells are a unique subset of IL-12- and IL-15-responsive IFN-gamma-producing cells Immunity 38 2013 769 781
    • (2013) Immunity , vol.38 , pp. 769-781
    • Fuchs, A.1    Vermi, W.2    Lee, J.S.3
  • 15
    • 84929663292 scopus 로고    scopus 로고
    • The unusual suspects - Innate lymphoid cells: Novel therapeutic targets in IBD
    • R. Goldberg, N. Prescott, G.M. Lord, and et al. The unusual suspects - innate lymphoid cells: novel therapeutic targets in IBD Nat Rev Gastroenterol Hepatol 12 2015 271 283
    • (2015) Nat Rev Gastroenterol Hepatol , vol.12 , pp. 271-283
    • Goldberg, R.1    Prescott, N.2    Lord, G.M.3
  • 16
    • 84866362664 scopus 로고    scopus 로고
    • IL-1beta mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4(+) Th17 cells
    • M. Coccia, O.J. Harrison, C. Schiering, and et al. IL-1beta mediates chronic intestinal inflammation by promoting the accumulation of IL-17A secreting innate lymphoid cells and CD4(+) Th17 cells J Exp Med 209 2012 1595 1609
    • (2012) J Exp Med , vol.209 , pp. 1595-1609
    • Coccia, M.1    Harrison, O.J.2    Schiering, C.3
  • 17
    • 84903442371 scopus 로고    scopus 로고
    • Nod/Ripk2 signaling in dendritic cells activates IL-17A-secreting innate lymphoid cells and drives colitis in T-bet-/-.Rag2-/- (TRUC) mice
    • J. Ermann, T. Staton, J.N. Glickman, and et al. Nod/Ripk2 signaling in dendritic cells activates IL-17A-secreting innate lymphoid cells and drives colitis in T-bet-/-.Rag2-/- (TRUC) mice Proc Natl Acad Sci U S A 111 2014 E2559 E2566
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. E2559-E2566
    • Ermann, J.1    Staton, T.2    Glickman, J.N.3
  • 18
    • 72549107316 scopus 로고    scopus 로고
    • Differential regulation of interleukin 17 and interferon gamma production in inflammatory bowel disease
    • L. Rovedatti, T. Kudo, P. Biancheri, and et al. Differential regulation of interleukin 17 and interferon gamma production in inflammatory bowel disease Gut 58 2009 1629 1636
    • (2009) Gut , vol.58 , pp. 1629-1636
    • Rovedatti, L.1    Kudo, T.2    Biancheri, P.3
  • 19
    • 9144231336 scopus 로고    scopus 로고
    • Interleukin-6-dependent gene expression profiles in multiple myeloma INA-6 cells reveal a Bcl-2 family-independent survival pathway closely associated with Stat3 activation
    • K. Brocke-Heidrich, A.K. Kretzschmar, G. Pfeifer, and et al. Interleukin-6-dependent gene expression profiles in multiple myeloma INA-6 cells reveal a Bcl-2 family-independent survival pathway closely associated with Stat3 activation Blood 103 2004 242 251
    • (2004) Blood , vol.103 , pp. 242-251
    • Brocke-Heidrich, K.1    Kretzschmar, A.K.2    Pfeifer, G.3
  • 20
    • 84876806691 scopus 로고    scopus 로고
    • Dynamic regulatory network controlling TH17 cell differentiation
    • N. Yosef, A.K. Shalek, J.T. Gaublomme, and et al. Dynamic regulatory network controlling TH17 cell differentiation Nature 496 2013 461 468
    • (2013) Nature , vol.496 , pp. 461-468
    • Yosef, N.1    Shalek, A.K.2    Gaublomme, J.T.3
  • 21
    • 45549097533 scopus 로고    scopus 로고
    • IL-6-dependent mucosal protection prevents establishment of a microbial niche for attaching/effacing lesion-forming enteric bacterial pathogens
    • S.M. Dann, M.E. Spehlmann, D.C. Hammond, and et al. IL-6-dependent mucosal protection prevents establishment of a microbial niche for attaching/effacing lesion-forming enteric bacterial pathogens J Immunol 180 2008 6816 6826
    • (2008) J Immunol , vol.180 , pp. 6816-6826
    • Dann, S.M.1    Spehlmann, M.E.2    Hammond, D.C.3
  • 22
    • 84873729246 scopus 로고    scopus 로고
    • A T-bet gradient controls the fate and function of CCR6-RORgammat+ innate lymphoid cells
    • C.S. Klose, E.A. Kiss, V. Schwierzeck, and et al. A T-bet gradient controls the fate and function of CCR6-RORgammat+ innate lymphoid cells Nature 494 2013 261 265
    • (2013) Nature , vol.494 , pp. 261-265
    • Klose, C.S.1    Kiss, E.A.2    Schwierzeck, V.3
  • 23
    • 0027451455 scopus 로고
    • Enhanced secretion of tumour necrosis factor-alpha, IL-6, and IL-1 beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease
    • H.C. Reinecker, M. Steffen, T. Witthoeft, and et al. Enhanced secretion of tumour necrosis factor-alpha, IL-6, and IL-1 beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease Clin Exp Immunol 94 1993 174 181
    • (1993) Clin Exp Immunol , vol.94 , pp. 174-181
    • Reinecker, H.C.1    Steffen, M.2    Witthoeft, T.3
  • 24
    • 0025599882 scopus 로고
    • Significant increase of interleukin 6 production in blood mononuclear leukocytes obtained from patients with active inflammatory bowel disease
    • Y. Suzuki, H. Saito, J. Kasanuki, and et al. Significant increase of interleukin 6 production in blood mononuclear leukocytes obtained from patients with active inflammatory bowel disease Life Sci 47 1990 2193 2197
    • (1990) Life Sci , vol.47 , pp. 2193-2197
    • Suzuki, Y.1    Saito, H.2    Kasanuki, J.3
  • 25
    • 0027313034 scopus 로고
    • Relationship of functional and antigenic interleukin 6 to disease activity in inflammatory bowel disease
    • J.S. Hyams, J.E. Fitzgerald, W.R. Treem, and et al. Relationship of functional and antigenic interleukin 6 to disease activity in inflammatory bowel disease Gastroenterology 104 1993 1285 1292
    • (1993) Gastroenterology , vol.104 , pp. 1285-1292
    • Hyams, J.S.1    Fitzgerald, J.E.2    Treem, W.R.3
  • 26
    • 76149132672 scopus 로고    scopus 로고
    • Early-onset Crohn disease is associated with male sex and a polymorphism in the IL-6 promoter
    • K. Sagiv-Friedgut, A. Karban, B. Weiss, and et al. Early-onset Crohn disease is associated with male sex and a polymorphism in the IL-6 promoter J Pediatr Gastroenterol Nutr 50 2010 22 26
    • (2010) J Pediatr Gastroenterol Nutr , vol.50 , pp. 22-26
    • Sagiv-Friedgut, K.1    Karban, A.2    Weiss, B.3
  • 27
    • 10044264634 scopus 로고    scopus 로고
    • Pivotal roles of interleukin-6 in transmural inflammation in murine T cell transfer colitis
    • K. Kitamura, Y. Nakamoto, S. Kaneko, and et al. Pivotal roles of interleukin-6 in transmural inflammation in murine T cell transfer colitis J Leukoc Biol 76 2004 1111 1117
    • (2004) J Leukoc Biol , vol.76 , pp. 1111-1117
    • Kitamura, K.1    Nakamoto, Y.2    Kaneko, S.3
  • 28
    • 16644392805 scopus 로고    scopus 로고
    • Reduced intestinal inflammation induced by dextran sodium sulfate in interleukin-6-deficient mice
    • Y. Naito, T. Takagi, K. Uchiyama, and et al. Reduced intestinal inflammation induced by dextran sodium sulfate in interleukin-6-deficient mice Int J Mol Med 14 2004 191 196
    • (2004) Int J Mol Med , vol.14 , pp. 191-196
    • Naito, Y.1    Takagi, T.2    Uchiyama, K.3
  • 29
    • 33747774200 scopus 로고    scopus 로고
    • STAT3 activation via interleukin 6 trans-signalling contributes to ileitis in SAMP1/Yit mice
    • K. Mitsuyama, S. Matsumoto, S. Rose-John, and et al. STAT3 activation via interleukin 6 trans-signalling contributes to ileitis in SAMP1/Yit mice Gut 55 2006 1263 1269
    • (2006) Gut , vol.55 , pp. 1263-1269
    • Mitsuyama, K.1    Matsumoto, S.2    Rose-John, S.3
  • 30
    • 18344410191 scopus 로고    scopus 로고
    • Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in Crohn disease and experimental colitis in vivo
    • R. Atreya, J. Mudter, S. Finotto, and et al. Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in Crohn disease and experimental colitis in vivo Nat Med 6 2000 583 588
    • (2000) Nat Med , vol.6 , pp. 583-588
    • Atreya, R.1    Mudter, J.2    Finotto, S.3
  • 31
    • 84355162720 scopus 로고    scopus 로고
    • Priming microenvironments dictate cytokine requirements for T helper 17 cell lineage commitment
    • W. Hu, T.D. Troutman, R. Edukulla, and et al. Priming microenvironments dictate cytokine requirements for T helper 17 cell lineage commitment Immunity 35 2011 1010 1022
    • (2011) Immunity , vol.35 , pp. 1010-1022
    • Hu, W.1    Troutman, T.D.2    Edukulla, R.3
  • 32
    • 45749107055 scopus 로고    scopus 로고
    • Unique CD14 intestinal macrophages contribute to the pathogenesis of Crohn disease via IL-23/IFN-gamma axis
    • N. Kamada, T. Hisamatsu, S. Okamoto, and et al. Unique CD14 intestinal macrophages contribute to the pathogenesis of Crohn disease via IL-23/IFN-gamma axis J Clin Invest 118 2008 2269 2280
    • (2008) J Clin Invest , vol.118 , pp. 2269-2280
    • Kamada, N.1    Hisamatsu, T.2    Okamoto, S.3
  • 33
    • 30944466824 scopus 로고    scopus 로고
    • Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach
    • C. Manichanh, L. Rigottier-Gois, E. Bonnaud, and et al. Reduced diversity of faecal microbiota in Crohn's disease revealed by a metagenomic approach Gut 55 2006 205 211
    • (2006) Gut , vol.55 , pp. 205-211
    • Manichanh, C.1    Rigottier-Gois, L.2    Bonnaud, E.3
  • 34
    • 2342442430 scopus 로고    scopus 로고
    • Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease
    • S.J. Ott, M. Musfeldt, D.F. Wenderoth, and et al. Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease Gut 53 2004 685 693
    • (2004) Gut , vol.53 , pp. 685-693
    • Ott, S.J.1    Musfeldt, M.2    Wenderoth, D.F.3
  • 35
    • 40749114497 scopus 로고    scopus 로고
    • Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): A double-blind, placebo-controlled, randomised trial
    • J.S. Smolen, A. Beaulieu, A. Rubbert-Roth, and et al. Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial Lancet 371 2008 987 997
    • (2008) Lancet , vol.371 , pp. 987-997
    • Smolen, J.S.1    Beaulieu, A.2    Rubbert-Roth, A.3
  • 36
    • 40749152243 scopus 로고    scopus 로고
    • Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: A randomised, double-blind, placebo-controlled, withdrawal phase III trial
    • S. Yokota, T. Imagawa, M. Mori, and et al. Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled, withdrawal phase III trial Lancet 371 2008 998 1006
    • (2008) Lancet , vol.371 , pp. 998-1006
    • Yokota, S.1    Imagawa, T.2    Mori, M.3
  • 37
    • 75749113331 scopus 로고    scopus 로고
    • Tocilizumab in systemic lupus erythematosus: Data on safety, preliminary efficacy, and impact on circulating plasma cells from an open-label phase i dosage-escalation study
    • G.G. Illei, Y. Shirota, C.H. Yarboro, and et al. Tocilizumab in systemic lupus erythematosus: data on safety, preliminary efficacy, and impact on circulating plasma cells from an open-label phase I dosage-escalation study Arthritis Rheum 62 2010 542 552
    • (2010) Arthritis Rheum , vol.62 , pp. 542-552
    • Illei, G.G.1    Shirota, Y.2    Yarboro, C.H.3
  • 38
    • 11144358366 scopus 로고    scopus 로고
    • A pilot randomized trial of a human anti-interleukin-6 receptor monoclonal antibody in active Crohn's disease
    • discussion 947
    • H. Ito, M. Takazoe, Y. Fukuda, and et al. A pilot randomized trial of a human anti-interleukin-6 receptor monoclonal antibody in active Crohn's disease Gastroenterology 126 2004 989 996 discussion 947
    • (2004) Gastroenterology , vol.126 , pp. 989-996
    • Ito, H.1    Takazoe, M.2    Fukuda, Y.3
  • 39
    • 84886947164 scopus 로고    scopus 로고
    • The challenges of stratifying patients for trials in inflammatory bowel disease
    • P. Biancheri, N. Powell, G. Monteleone, and et al. The challenges of stratifying patients for trials in inflammatory bowel disease Trends Immunol 34 2013 564 571
    • (2013) Trends Immunol , vol.34 , pp. 564-571
    • Biancheri, P.1    Powell, N.2    Monteleone, G.3
  • 40
    • 84884251320 scopus 로고    scopus 로고
    • Development of a dual-index sequencing strategy and curation pipeline for analyzing amplicon sequence data on the MiSeq Illumina sequencing platform
    • J.J. Kozich, S.L. Westcott, N.T. Baxter, and et al. Development of a dual-index sequencing strategy and curation pipeline for analyzing amplicon sequence data on the MiSeq Illumina sequencing platform Appl Environ Microbiol 79 2013 5112 5120
    • (2013) Appl Environ Microbiol , vol.79 , pp. 5112-5120
    • Kozich, J.J.1    Westcott, S.L.2    Baxter, N.T.3
  • 41
    • 79251565226 scopus 로고    scopus 로고
    • Removing noise from pyrosequenced amplicons
    • C. Quince, A. Lanzen, R.J. Davenport, and et al. Removing noise from pyrosequenced amplicons BMC Bioinform 12 2011 38
    • (2011) BMC Bioinform , vol.12 , pp. 38
    • Quince, C.1    Lanzen, A.2    Davenport, R.J.3
  • 42
    • 66249145772 scopus 로고    scopus 로고
    • Statistical methods for detecting differentially abundant features in clinical metagenomic samples
    • J.R. White, N. Nagarajan, and M. Pop Statistical methods for detecting differentially abundant features in clinical metagenomic samples PLoS Comp Biol 5 2009 e1000352
    • (2009) PLoS Comp Biol , vol.5 , pp. e1000352
    • White, J.R.1    Nagarajan, N.2    Pop, M.3
  • 43
    • 79960004119 scopus 로고    scopus 로고
    • Interactive tree of life v2: Online annotation and display of phylogenetic trees made easy
    • I. Letunic, and P. Bork Interactive tree of life v2: online annotation and display of phylogenetic trees made easy Nucleic Acids Res 39 2011 W475 W478
    • (2011) Nucleic Acids Res , vol.39 , pp. W475-W478
    • Letunic, I.1    Bork, P.2


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