Long term effects of residential NOx exposure on total and cause-specific mortality and incidence of myocardial infarction in a Swedish cohort

Environmental Research

Volumn 142, Issue , 2015, Pages 197-206

  Stockfelt, Leo ^a   Andersson, Eva M ^a   Molnár, Peter ^a   Rosengren, Annika ^a   Wilhelmsen, Lars ^a   Sallsten, Gerd ^a   Barregard, Lars ^a  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Air pollution; Cardiovascular disease; Cohort studies; Mortality; Myocardial infarction

Indexed keywords

CHOLESTEROL; HYPERTENSIVE AGENT; NITROGEN OXIDE; AIR POLLUTANT;

AIR QUALITY; ATMOSPHERIC POLLUTION; CARDIOVASCULAR DISEASE; COHORT ANALYSIS; DISEASE INCIDENCE; LONG-TERM CHANGE; MORTALITY; NITROGEN OXIDES; POLLUTION EXPOSURE;

ADULT; AIR POLLUTION; AIR QUALITY; ARTICLE; ATMOSPHERIC DISPERSION; CARDIOVASCULAR MORTALITY; CAUSE OF DEATH; CEREBROVASCULAR DISEASE; CHOLESTEROL BLOOD LEVEL; COHORT ANALYSIS; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; EFFECT SIZE; ENVIRONMENTAL EXPOSURE; GENETIC DISORDER; HEALTH HAZARD; HEART INFARCTION; HEREDITY; HUMAN; HYPERTENSION; HYPOTENSION; INCIDENCE; ISCHEMIC HEART DISEASE; LONG TERM EXPOSURE; MAJOR CLINICAL STUDY; MALE; MENTAL STRESS; MIDDLE AGED; MORTALITY; OCCUPATIONAL HAZARD; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RESPIRATORY TRACT DISEASE; RISK FACTOR; SMOKING; SOCIAL STATUS; SWEDISH CITIZEN; SYSTOLIC BLOOD PRESSURE; WHITE COLLAR WORKER; AIR POLLUTANT; ANALYSIS; DEMOGRAPHY; MYOCARDIAL INFARCTION; SWEDEN;

GOTEBORG; SWEDEN; VASTRA GOTALAND;

AIR POLLUTANTS; CAUSE OF DEATH; COHORT STUDIES; ENVIRONMENTAL EXPOSURE; HUMANS; INCIDENCE; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; NITROGEN OXIDES; RESIDENCE CHARACTERISTICS; SWEDEN;

EID: 84936866249     PISSN: 00139351     EISSN: 10960953     Source Type: Journal    
DOI: 10.1016/j.envres.2015.06.045     Document Type: Article

References (52)

1. Beelen R., Raaschou-Nielsen O., Stafoggia M., Andersen Z.J., Weinmayr G., Hoffmann B., et al. Effects of long-term exposure to air pollution on natural-cause mortality: an analysis of 22 European cohorts within the multicentre ESCAPE project. Lancet 2014, 383:785-795.
2. Beelen R., Voogt M., Duyzer J., Zandveld P., Hoek G. Comparison of the performances of land use regression modelling and dispersion modelling in estimating small-scale variations in long-term air pollution concentrations in a Dutch urban area. Atmos. Environ. 2010, 44:4614-4621.
3. Berg J., Bjorck L., Lappas G., O'Flaherty M., Capewell S., Rosengren A. Continuing decrease in coronary heart disease mortality in Sweden. BMC Cardiovasc. Disord. 2014, 14:9.
4. Berrington de Gonzalez A., Hartge P., Cerhan J.R., Flint A.J., Hannan L., MacInnis R.J., et al. Body-mass index and mortality among 1.46 million white adults. N. Engl. J. Med. 2010, 363:2211-2219.
5. Bjorck L., Capewell S., O'Flaherty M., Lappas G., Bennett K., Rosengren A. Decline in coronary mortality in Sweden between 1986 and 2002: comparing contributions from primary and secondary prevention. PLoS One 2015, 10:e0124769.
6. Brook R.D., Rajagopalan S., Pope C.A., Brook J.R., Bhatnagar A., Diez-Roux A.V., et al. Particulate matter air pollution and cardiovascular disease: an update to the scientific statement from the American Heart Association. Circulation 2010, 121:2331-2378.
7. Carey I.M., Atkinson R.W., Kent A.J., van Staa T., Cook D.G., Anderson H.R. Mortality associations with long-term exposure to outdoor air pollution in a national English cohort. Am. J. Respir. Crit. Care Med. 2013, 187:1226-1233.
8. Cesaroni G., Badaloni C., Gariazzo C., Stafoggia M., Sozzi R., Davoli M., Forastiere F. Long-term exposure to urban air pollution and mortality in a cohort of more than a million adults in Rome. Environ. Health Perspect. 2013, 121:324-331.
9. Cesaroni G., Forastiere F., Stafoggia M., Andersen Z.J., Badaloni C., Beelen R., et al. Long term exposure to ambient air pollution and incidence of acute coronary events: prospective cohort study and meta-analysis in 11 European cohorts from the ESCAPE Project. Br. Med. J. 2014, 348:f7412.
10. Chen L.H., Knutsen S.F., Shavlik D., Beeson W.L., Petersen F., Ghamsary M., et al. The association between fatal coronary heart disease and ambient particulate air pollution: are females at greater risk?. Environ. Health Perspect. 2005, 113:1723-1729.
11. Dockery D.W., Pope C.A., Xu X., Spengler J.D., Ware J.H., Fay M.E., et al. An association between air pollution and mortality in six U.S. cities. N. Engl. J. Med. 1993, 329:1753-1759.
12. Donaldson K., Mills N., MacNee W., Robinson S., Newby D. Role of inflammation in cardiopulmonary health effects of PM. Toxicol. Appl. Pharmacol. 2005, 207:483-488.
13. Elliott P., Shaddick G., Wakefield J.C., Cd Hoogh, Briggs D.J. Long-term associations of outdoor air pollution with mortality in Great Britain. Thorax 2007, 62:1088-1094.
14. Faustini A., Rapp R., Forastiere F. Nitrogen dioxide and mortality: review and meta-analysis of long-term studies. Eur. Respir. J. 2014.
15. Filleul L., Rondeau V., Vandentorren S., Le Moual N., Cantagrel A., Annesi-Maesano I., et al. Twenty five year mortality and air pollution: results from the French PAARC survey. Occup. Environ. Med. 2005, 62:453-460.
16. Forsberg B., Hansson H.C., Johansson C., Areskoug H., Persson K., Jarvholm B. Comparative health impact assessment of local and regional particulate air pollutants in Scandinavia. AMBIO 2005, 34:11-19.
17. Gan W.Q., Koehoorn M., Davies H.W., Demers P.A., Tamburic L., Brauer M. Long-term exposure to traffic-related air pollution and the risk of coronary heart disease hospitalization and mortality. Environ. Health Perspect. 2011, 119:501-507.
18. Hoek G., Brunekreef B., Goldbohm S., Fischer P., van den Brandt P.A. Association between mortality and indicators of traffic-related air pollution in the Netherlands: a cohort study. Lancet 2002, 360:1203-1209.
19. Hoek G., Krishnan R., Beelen R., Peters A., Ostro B., Brunekreef B., et al. Long-term air pollution exposure and cardio- respiratory mortality: a review. Environ. Health 2013, 12:43.
20. Janhall S., Hallquist M. A novel method for determination of size resolved, submicrometer particle traffic emission factors. Environ. Sci. Technol. 2005, 39:7609-7615.
21. Johansson C., Burman L., Forsberg B. The effects of congestions tax on air quality and health. Atmos. Environ. 2009, 43:4843-4854.
22. Johansson C., Norman M., Gidhagen L. Spatial and temporal variations of PM10 and particle number concentrations in urban air. Environ. Monit. Assess. 2007, 127:477-487.
23. Kan H., London S.J., Chen G., Zhang Y., Song G., Zhao N., et al. Season, sex, age, and education as modifiers of the effects of outdoor air pollution on daily mortality in Shanghai, China: the Public Health and Air Pollution in Asia (PAPA) Study. Environ. Health Perspect. 2008, 116:1183-1188.
24. Kwasny F., Madl P., Hofmann W. Correlation of air quality data to Ultrafine Particles (UFP) concentration and size distribution in ambient air. Atmosphere 2010, 1:3-14.
25. Lepeule J., Laden F., Dockery D., Schwartz J. Chronic exposure to fine particles and mortality: an extended follow-up of the Harvard Six Cities study from 1974 to 2009. Environ Health Perspect. 2012.
26. Miller K.A., Siscovick D.S., Sheppard L., Shepherd K., Sullivan J.H., Anderson G.L., et al. Long-term exposure to air pollution and incidence of cardiovascular events in women. N. Engl. J. Med. 2007, 356:447-458.
27. Mills N.L., Tornqvist H., Robinson S.D., Gonzalez M., Darnley K., MacNee W., et al. Diesel exhaust inhalation causes vascular dysfunction and impaired endogenous fibrinolysis. Circulation 2005, 112:3930-3936.
28. Mills N.L., Törnqvist H., Gonzalez M.C., Vink E., Robinson S.D., Söderberg S., et al. Ischemic and thrombotic effects of dilute diesel-exhaust inhalation in men with coronary heart disease. N. Engl. J. Med. 2007, 357:1075-1082.
29. Molnár P., Johannesson S., Boman J., Barregard L., Sallsten G. Personal exposures and indoor, residential outdoor, and urban background levels of fine particle trace elements in the general population. J. Environ. Monit. 2006, 8(5):543-551.
30. x exposure in a 35-year cohort study. Changes of exposure, and comparison with back extrapolation for historical exposure assessment. Atmos. Environ. 2015, 115:62-69.
31. Nafstad P., Haheim L.L., Wisloff T., Gram F., Oftedal B., Holme I., et al. Urban air pollution and mortality in a cohort of Norwegian men. Environ. Health Perspect. 2004, 112:610-615.
32. Pope C.A. Mortality effects of longer term exposures to fine particulate air pollution: review of recent epidemiological evidence. Inhal. Toxicol 2007, 19(Suppl 1):S33-S38.
33. Pope C.A., Burnett R.T., Thun M.J., Calle E.E., Krewski D, Ito K., et al. Lung cancer, cardiopulmonary mortality, and long-term exposure to fine particulate air pollution. J. Am Med. Assoc. 2002, 287:1132-1141.
34. Pope C.A., Thun M.J., Namboodiri M.M., Dockery D.W., Evans J.S., Speizer F.E., et al. Particulate air pollution as a predictor of mortality in a prospective study of U.S. adults. Am. J. Respir. Crit. Care Med. 1995, 151:669-674.
35. Puett R.C., Hart J.E., Suh H., Mittleman M., Laden F. Particulate matter exposures, mortality, and cardiovascular disease in the health professionals follow-up study. Environ. Health Perspect. 2011, 119:1130-1135.
36. Puett R.C., Hart J.E., Yanosky J.D., Paciorek C., Schwartz J., Suh H., et al. Chronic fine and coarse particulate exposure, mortality, and coronary heart disease in the Nurses' Health Study. Environ. Health Perspect. 2009, 117:1697-1701.
37. Puett R.C., Schwartz J., Hart J.E., Yanosky J.D., Speizer F.E., Suh H., et al. Chronic particulate exposure, mortality, and coronary heart disease in the nurses' health study. Am. J. Epidemiol. 2008, 168:1161-1168.
38. R Development Core Team, 2015. The R Foundation for Statistical Computing, Vienna, Austria. Available: (Accessed 24.03.2015). http://www.r-project.org.
39. Raaschou-Nielsen O., Andersen Z., Jensen S., Ketzel M., Sorensen M., Hansen J., et al. Traffic air pollution and mortality from cardiovascular disease and all causes: a Danish cohort study. Environ. Health 2012, 11:60.
40. Rosengren A., Fredén M., Hansson P.O., Wilhelmsen L., Wedel H., Eriksson H. Psychosocial factors and venous thromboembolism: a long-term follow-up study of Swedish men. J. Thrombosis Haemostasis 2008, 6:558-564.
41. Rosengren A., Wedel H., Wilhelmsen L. Coronary Heart Disease And Mortality In Middle Aged Men From Different Occupational Classes In Sweden. BMJ: British Med. J. 1988, 1497-1500.
42. Rosenlund M., Bellander T., Nordquist T., Alfredsson L. Traffic-generated air pollution and myocardial infarction. Epidemiology 2009, 20:265-271.
43. Rosenlund M., Berglind N., Pershagen G., Hallqvist J., Jonson T., Bellander T. Long-term exposure to urban air pollution and myocardial infarction. Epidemiology 2006, 17:383-390.
44. Rosenlund M., Picciotto S., Forastiere F., Stafoggia M., Perucci C.A. Traffic-related air pollution in relation to incidence and prognosis of coronary heart disease. Epidemiology 2008, 19:121-128.
45. Sánchez Jiménez A., Heal M.R., Beverland I.J. Correlations of particle number concentrations and metals with nitrogen oxides and other traffic-related air pollutants in Glasgow and London. Atmos. Environ. 2012, 54:667-678.
46. Schwartz J., Coull B., Laden F., Ryan L. The effect of dose and timing of dose on the association between airborne particles and survival. Environ. Health Perspect. 2008, 116:64-69.
47. WHO WHO Air Quality Guidelines Global Update 2005 2006, World Health Organization, Regional Office for Europe, Bonn, Germany, Copenhagen, Denmark.
48. WHO, 2013. Review of Evidence on Health Aspects of Air Pollution-REVIHAAP Project. Copenhagen, Denmark.
49. Wilhelmsen L., Berglund G., Elmfeldt D., Tibblin G., Wedel H., Pennert K., et al. The multifactor primary prevention trial in Göteborg, Sweden. Eur. Heart J. 1986, 7:279-288.
50. Wilhelmsen L., Lappas G., Rosengren A. Risk of coronary events by baseline factors during 28 years follow-up and three periods in a random population sample of men. J. Intern. Med. 2004, 256:298-307.
51. Wilhelmsen L., Tibblin G., Werkö L. A primary preventive study in Gothenburg, Sweden. Prev. Med. 1972, 1:153-160.
52. Wilhelmsen L., Welin L., Svärdsudd K., Wedel H., Eriksson H., Hansson P.O., et al. Secular changes in cardiovascular risk factors and attack rate of myocardial infarction among men aged 50 in Gothenburg, Sweden. Accurate prediction using risk models. J. Intern. Medicine 2008, 263:636-643.