Synthesis of 2-deoxy-2,2-difluoro-α-maltosyl fluoride and its X-ray structure in complex with Streptomyces coelicolor GlgEI-V279S

Organic and Biomolecular Chemistry

Volumn 13, Issue 27, 2015, Pages 7542-7550

  Thanna, Sandeep ^a   Lindenberger, Jared J ^a   Gaitonde, Vishwanath V ^a   Ronning, Donald R ^a   Sucheck, Steven J ^a  

^a UNIVERSITY OF TOLEDO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; BIOCHEMISTRY; FLUORINE COMPOUNDS; SYNTHESIS (CHEMICAL); TUBES (COMPONENTS);

CATALYTIC RESIDUE; COVALENT BOND FORMATION; GLYCOSIDE HYDROLASES; HYDROGEN BOND ACCEPTORS; INHIBITOR DESIGN; LOWER RESOLUTION; MYCOBACTERIUM TUBERCULOSIS; STREPTOMYCES COELICOLOR;

HYDROGEN BONDS;

MYCOBACTERIUM TUBERCULOSIS; STREPTOMYCES COELICOLOR;

2-DEOXY-2,2-DIFLUORO-ALPHA-MALTOSYL FLUORIDE; ENZYME INHIBITOR; GLYCOSIDASE; MALTOSE;

ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; BIOASSAY; BIOCATALYSIS; CHEMISTRY; DRUG EFFECTS; ENZYME SPECIFICITY; ENZYMOLOGY; MOLECULAR MODEL; STREPTOMYCES COELICOLOR; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

BIOCATALYSIS; BIOLOGICAL ASSAY; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; GLYCOSIDE HYDROLASES; MALTOSE; MODELS, MOLECULAR; STREPTOMYCES COELICOLOR; SUBSTRATE SPECIFICITY;

EID: 84936853275     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/c5ob00867k     Document Type: Article

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