Separation and purification of five alkaloids from Aconitum duclouxii by counter-current chromatography

Journal of Separation Science

Volumn 38, Issue 13, 2015, Pages 2320-2326

  Wang, Yarong ^a   Cai, Shining ^a   Chen, Yang ^a   Deng, Liang ^b   Zhou, Xumei ^a   Liu, Jia ^a   Xu, Xin ^a   Xia, Qiang ^a   Lin, Mao ^a   Zhang, Jili ^a   Huang, Weili ^a   Wang, Wenjun ^a   Xiang, Canhui ^a   Cui, Guozhen ^a   Du, Lianfeng ^a   He, Huan ^a   Qi, Baohui ^a  

^a ZUNYI MEDICAL UNIVERSITY   (China)

^b KUNMING MEDICAL UNIVERSITY   (China)

Author keywords

Aconitum duclouxii L; C19 diterpenoid alkaloids; Counter current chromatography

Indexed keywords

ALKALOIDS; HEXANE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPIDS; LIQUID CHROMATOGRAPHY; METABOLITES; NITROGEN COMPOUNDS; ORGANIC SOLVENTS; PURIFICATION; SEPARATION; VOLATILE FATTY ACIDS;

ACONITUM ALKALOIDS; ACONITUM DUCLOUXII L; COUNTERCURRENT CHROMATOGRAPHY; DITERPENOID; ETHYL ACETATE EXTRACTION; SEPARATION AND PURIFICATION; TWO-PHASE SOLVENT SYSTEM; ULTRA-HIGH PERFORMANCE LIQUID CHROMATOGRAPHIES;

CHROMATOGRAPHY;

ACETIC ACID ETHYL ESTER; ACONITINE; ALKALOID DERIVATIVE; AMMONIA; BENZOYLACONINE; DEOXYACONITINE; DITERPENOID; DUCLOUDINE A; HEXANE; METHANOL; N DEETHYLACONITINE; PLANT MEDICINAL PRODUCT; SOLVENT; UNCLASSIFIED DRUG; WATER; ALKALOID;

ACONITE; ACONITUM DUCLOUXII; ARTICLE; CHEMICAL ANALYSIS; CHEMICAL COMPOSITION; CHEMICAL STRUCTURE; COUNTER CURRENT CHROMATOGRAPHY; DRUG DETERMINATION; DRUG PURIFICATION; MEDICINAL PLANT; NONHUMAN; PHASE SEPARATION; PLANT ROOT; PRIORITY JOURNAL; PROCESS OPTIMIZATION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROCEDURES;

ACONITUM;

ACONITUM; ALKALOIDS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COUNTERCURRENT DISTRIBUTION; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84936847042     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.201500059     Document Type: Article

References (30)

1. Hazawa, M., Wada, K., Takahashi, K., Mori, T., Kawahara, N., Kashiwakura, I., Invest. New Drugs 2009, 27, 111-119.
2. Shu, H., Hayashida, M., Chiba, S., Sekiyama, H., Kitamura, T., Yamada, Y., Hanaoka, K., Arita, H., J. Ethnopharmacol. 2007, 113, 560-563.
3. Ameri, A., Prog. Neurobiol. 1998, 56, 211-223.
4. Wang, F. P., Chen, Q. H., Liu, X. Y., Diterpenoid alkaloids, Nat. Prod. Rep. 2010, 27, 529-570.
5. People's Government of Dali Bai Autonomous Prefecture, The Natural Resources of Chinese Medicinal Materials of Dali, Yunnan Ethnic Publishing House, Kunming 1991, p. 77.
6. Yin, T. P., Cai, L., Lei, G., Dong, J. W., Liu, Y. X., Ding, Z. T., Chin. J. Org. Chem. 2013, 33, 2528-2532.
7. Yin, T. P., Cai, L., Lei, G., He, J. M., Dong, J. W., Fang, H. X., Zhou, H., Ding, Z. T., J. Asian. Nat. Prod. Res. 2014, 16, 345-350.
8. Yin, T. P., Cai, L., Zhou, H., Zhu, X. F., Chen, Y., Ding, Z. T., Nat. Prod. Res. 2014, 28, 1649-1654.
9. Wang, C. Y., Chen, J. B., Zhu, R. H., Acta. Pharm. Sin. 1984, 19, 445.
10. Dzhakhagirov, F. N., Sultankhodzhaev, M. N., Tashkhodzhaev, B., Silmov, B. T., Khim. Prir. Soedin. 1997, 33, 254-270.
11. Pelletier, S. W., The Alkaloids: Chemical and Biological Perspectives, Springer Verlag Press, New York, 1983, pp. 120-153.
12. Wang, F. P., Liang, X. T., The Alkaloids: Chemistry and Pharmacology, Academic Press, New York, 1992, pp. 151-247.
13. Panter, K. E., Manners, G. D., Stegelmeier, B. L., Gardner, D. R., Ralphs, M. H., Pfister, J. A., James, L. F., Biochem. Syst. Ecol. 2002, 30, 113-128.
14. Ito, Y., Weinstein, M., Aoki, I., Harada, R., Kimura, E., Nunogaki, K., Nature 1966, 212, 985-987.
15. Jubert, C., Baiiley, G., J. Chromatogr. A 2007, 1140, 95-100.
16. Cao, X. L., Ito, Y., J. Chromatogr. A 2003, 1021, 117-124.
17. Du, Q. Z., Li, L., Jerz, G., J. Chromatogr. A 2005, 1077, 98-101.
18. Sun, A. L., Sun, Q. H., Liu, R. M., J. Sep. Sci. 2007, 30, 1013-1018.
19. Xu, H. N., He, C. H., Sep. Purif. Technol. 2007, 56, 85-89.
20. Tang, Q., Yang, C., Ye, W., Liu, J., Zhao, S., Phytochem. Anal. 2008, 19, 155-159.
21. Wang, X., Shu, X., Wang, X., Yu, J., Jing, F., Molecules 2014, 19, 12619-12629.
22. Yang, F., Ito, Y., J. Chromatogr. A 2002, 943, 219-225.
23. Tang, Q., Yang, C., Ye, W., Liu, J., Zhao, S., J. Chromatogr. A 2007, 1144, 203-207.
24. Yang, F., Ito, Y., J. Chromatogr. A 2002, 923, 281-285.
25. Liu, Y., Chen, T., Chen, C., Zou, D., Li, Y., Chin. J. Chromatogr. 2014, 32, 543-546.
26. Tang, Q., Liu, J., Xue, J., Ye, W., Zhang, Z., Yang, C., J. Chromatogr. B. 2008, 872, 181-185.
27. Liu, D. H., Shu, X. K., Wang, X., Fang, L., Huang, L. Q., Xi, X. J., Zheng, Z. J., Quim Nova. 2013, 36, 1366-1369.
28. Ito, Y., J. Chromatogr. A 2005, 1065, 145-168.
29. Ye, H. Y., Chen, L. J., Li, Y. F., Peng, A. H., Fu, A. F., Song, H., Tang, M. H., Luo, H. D., Luo, Y. F., Xu, Y. B., Shi, J. Y., Wei, Y. Q., J. Chromatogr. A 2008, 1178, 101-107.
30. Friesen, J. B., Pauli, G. F., J. Liq. Chromatogr. Rel. Technol. 2005, 28, 2777-2806.