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Volumn 20, Issue 7, 2015, Pages 874-883

Crowdsourcing in pharma: a strategic framework

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CLINICAL PHARMACY; COMMERCIAL PHENOMENA; COMMUNITY CARE; CONCEPTUAL FRAMEWORK; CROWDSOURCING; DRUG INDUSTRY; HEALTH CARE DELIVERY; HEALTH CARE ORGANIZATION; HEALTH SERVICE; HUMAN; INTERNET; MASS COMMUNICATION; PHARMACEUTICAL CARE; PUBLIC-PRIVATE PARTNERSHIP; STRATEGIC PLANNING; COMPETITIVE BEHAVIOR; COOPERATION; DRUG DEVELOPMENT; INTERDISCIPLINARY COMMUNICATION; ORGANIZATION; ORGANIZATION AND MANAGEMENT; PROBLEM SOLVING; PUBLIC RELATIONS;

EID: 84936846249     PISSN: 13596446     EISSN: 18785832     Source Type: Journal    
DOI: 10.1016/j.drudis.2015.01.011     Document Type: Review
Times cited : (25)

References (72)
  • 1
    • 84857743319 scopus 로고    scopus 로고
    • Diagnosing the decline in pharmaceutical R&D efficiency
    • J.W. Scannell Diagnosing the decline in pharmaceutical R&D efficiency Nat. Rev. Drug Discov. 11 2012 191 200
    • (2012) Nat. Rev. Drug Discov. , vol.11 , pp. 191-200
    • Scannell, J.W.1
  • 2
    • 84889024686 scopus 로고    scopus 로고
    • Models for open innovation in the pharmaceutical industry
    • A. Schuhmacher Models for open innovation in the pharmaceutical industry Drug Discov. Today 18 2013 1133 1137
    • (2013) Drug Discov. Today , vol.18 , pp. 1133-1137
    • Schuhmacher, A.1
  • 3
    • 77149134011 scopus 로고    scopus 로고
    • Deconstructing the drug development process: the new face of innovation
    • K.I. Kaitin Deconstructing the drug development process: the new face of innovation Clin. Pharmacol. Ther. 87 2010 356 361
    • (2010) Clin. Pharmacol. Ther. , vol.87 , pp. 356-361
    • Kaitin, K.I.1
  • 4
    • 84884675983 scopus 로고    scopus 로고
    • Estimation of the size of drug-like chemical space based on GDB-17 data
    • P.G. Polishchuk Estimation of the size of drug-like chemical space based on GDB-17 data J. Comput. Aided Mol. Des. 27 2013 675 679
    • (2013) J. Comput. Aided Mol. Des. , vol.27 , pp. 675-679
    • Polishchuk, P.G.1
  • 5
    • 82255175640 scopus 로고    scopus 로고
    • What makes a good drug target?
    • I. Gashaw What makes a good drug target? Drug Discov. Today 16 2011 1037 1043
    • (2011) Drug Discov. Today , vol.16 , pp. 1037-1043
    • Gashaw, I.1
  • 6
    • 44649098434 scopus 로고    scopus 로고
    • The network structure of exploration and exploitation
    • D. Lazer, and A. Friedman The network structure of exploration and exploitation Admin. Sci. Quart. 52 2007 667 694
    • (2007) Admin. Sci. Quart. , vol.52 , pp. 667-694
    • Lazer, D.1    Friedman, A.2
  • 7
    • 84936848726 scopus 로고    scopus 로고
    • We don't know it all: crowd computing to develop and refine predictive in silico models
    • West Dover, VT
    • J. Bentzien We don't know it all: crowd computing to develop and refine predictive in silico models The Gordon Research Conference on Computer-Aided Drug Design West Dover, VT 2013
    • (2013) The Gordon Research Conference on Computer-Aided Drug Design
    • Bentzien, J.1
  • 8
    • 21244441202 scopus 로고    scopus 로고
    • Pharma since 1870: a rising drug industry
    • A. Daemmrich, and M.E. Bowden Pharma since 1870: a rising drug industry Chem. Eng. News 83 2005 28 42
    • (2005) Chem. Eng. News , vol.83 , pp. 28-42
    • Daemmrich, A.1    Bowden, M.E.2
  • 11
    • 84876920284 scopus 로고    scopus 로고
    • Crowd computing: using competitive dynamics to develop and refine highly predictive models
    • J. Bentzien Crowd computing: using competitive dynamics to develop and refine highly predictive models Drug Discov. Today 18 2013 472 478
    • (2013) Drug Discov. Today , vol.18 , pp. 472-478
    • Bentzien, J.1
  • 12
    • 84876250018 scopus 로고    scopus 로고
    • Crowd-sourced soil data for Europe
    • W. Shelley Crowd-sourced soil data for Europe Nature 496 2013 300
    • (2013) Nature , vol.496 , pp. 300
    • Shelley, W.1
  • 13
    • 45949105508 scopus 로고    scopus 로고
    • Crowdsourcing as a model for problem solving
    • D.C. Brabham Crowdsourcing as a model for problem solving Convergence 14 2008 75 90
    • (2008) Convergence , vol.14 , pp. 75-90
    • Brabham, D.C.1
  • 15
    • 84936848727 scopus 로고    scopus 로고
    • http://www.nasa.gov/content/coeci/iss-longeron-challenge-completed/#.VBMYNWRdURQ
    • The ISS Longeron Challenge. Available at: http://www.topcoder.com/iss/longeron/; http://www.nasa.gov/content/coeci/iss-longeron-challenge-completed/#.VBMYNWRdURQ
    • The ISS Longeron Challenge
  • 16
    • 84936848728 scopus 로고    scopus 로고
    • https://community.topcoder.com/longcontest/?module=ViewProblemStatement&rd=16051&pm=13156
    • The Asteroid Tracker Challenge Available at: http://www.nasa.gov/content/nasa-ntl-asteroid-tracker-challenge/#.VBMY8mRdURQ; https://community.topcoder.com/longcontest/?module=ViewProblemStatement&rd=16051&pm=13156
    • The Asteroid Tracker Challenge
  • 17
    • 84961902328 scopus 로고    scopus 로고
    • http://www.topcoder.com/epa/
  • 18
    • 84961874879 scopus 로고    scopus 로고
    • http://www.topcoder.com/epa/toxcast/
  • 19
    • 84961904242 scopus 로고    scopus 로고
    • http://www.topcoder.com/epa/challenge-details/
  • 20
    • 84961900595 scopus 로고    scopus 로고
    • https://www.gequest.com/c/flight
  • 21
    • 84961902330 scopus 로고    scopus 로고
    • http://community.topcoder.com/longcontest/?module=ViewProblemStatement&rd=15637&pm=12525
  • 22
    • 84961872325 scopus 로고    scopus 로고
    • https://www.cog-genomics.org/plink2/credits
  • 23
    • 84873598227 scopus 로고    scopus 로고
    • Prize based contests can provide solutions to computational biology problems
    • K. Lakhani Prize based contests can provide solutions to computational biology problems Nat. Biotechnol. 31 2013 108 111
    • (2013) Nat. Biotechnol. , vol.31 , pp. 108-111
    • Lakhani, K.1
  • 24
    • 84903700854 scopus 로고    scopus 로고
    • Scientists see advances in deep-learning programs
    • J. Markoff Scientists see advances in deep-learning programs New York Times 2012 http://www.nytimes.com/2012/11/24/science/scientists-see-advances-in-deep-learning-a-part-of-artificial-intelligence.html?-r=1&
    • (2012) New York Times
    • Markoff, J.1
  • 25
    • 84961871567 scopus 로고    scopus 로고
    • https://www.crowdanalytix.com/contests/modeling - predict-exacerbation-in-patients-with-respiratory-diseases
  • 30
    • 84897774182 scopus 로고    scopus 로고
    • How Kaggle is changing how we work
    • T. Goetz How Kaggle is changing how we work Atlantic 2013 http://www.theatlantic.com/technology/archive/2013/04/how-kaggle-is-changing-how-we-work/274908/
    • (2013) Atlantic
    • Goetz, T.1
  • 31
    • 77955491294 scopus 로고    scopus 로고
    • Predicting protein structures with a multiplayer online game
    • S. Cooper Predicting protein structures with a multiplayer online game Nature 466 2010 756 760
    • (2010) Nature , vol.466 , pp. 756-760
    • Cooper, S.1
  • 32
    • 82755186510 scopus 로고    scopus 로고
    • Algorithm discovery by protein folding game players
    • F. Khatib Algorithm discovery by protein folding game players Proc. Natl. Acad. Sci. U. S. A. 108 2011 18949 18953
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 18949-18953
    • Khatib, F.1
  • 33
    • 84902438183 scopus 로고    scopus 로고
    • CrowdPhase: crowdsourcing the phase problem
    • J. Jorda CrowdPhase: crowdsourcing the phase problem Acta Cryst. D 70 2014 1538 1548
    • (2014) Acta Cryst. D , vol.70 , pp. 1538-1548
    • Jorda, J.1
  • 34
    • 9244255265 scopus 로고    scopus 로고
    • Groups of diverse problem solvers can outperform groups of high-ability problem solvers
    • L. Hong, and S.E. Page Groups of diverse problem solvers can outperform groups of high-ability problem solvers Proc. Natl. Acad. Sci. U. S. A. 101 2004 16385 16389
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 16385-16389
    • Hong, L.1    Page, S.E.2
  • 35
    • 84893093239 scopus 로고    scopus 로고
    • Online video game plugs players into remote-controlled biochemistry lab
    • J. Bohannon Online video game plugs players into remote-controlled biochemistry lab Science 343 2014 475
    • (2014) Science , vol.343 , pp. 475
    • Bohannon, J.1
  • 36
    • 84893831061 scopus 로고    scopus 로고
    • RNA design rules from a massive open laboratory
    • J. Lee RNA design rules from a massive open laboratory Proc. Natl. Acad. Sci. U. S. A. 111 2014 2122 2127
    • (2014) Proc. Natl. Acad. Sci. U. S. A. , vol.111 , pp. 2122-2127
    • Lee, J.1
  • 37
    • 57349146373 scopus 로고    scopus 로고
    • Lessons from the Netflix prize challenge, ACM SIGKDD
    • R.M. Bell, and Y. Koren Lessons from the Netflix prize challenge, ACM SIGKDD Explorations Newsletter 9 2007 75 79
    • (2007) Explorations Newsletter , vol.9 , pp. 75-79
    • Bell, R.M.1    Koren, Y.2
  • 38
    • 79953669701 scopus 로고    scopus 로고
    • Reflecting on the DARPA Red Balloon Challenge
    • J.C. Tang Reflecting on the DARPA Red Balloon Challenge Commun. ACM 54 2011 78 85
    • (2011) Commun. ACM , vol.54 , pp. 78-85
    • Tang, J.C.1
  • 39
    • 84873828589 scopus 로고    scopus 로고
    • The dynamics of standardization: three perspectives on standards in organization studies
    • N. Brunsson The dynamics of standardization: three perspectives on standards in organization studies Organization Studies 33 2012 613 632
    • (2012) Organization Studies , vol.33 , pp. 613-632
    • Brunsson, N.1
  • 40
    • 1542556689 scopus 로고
    • University-industry relationships in the life sciences: implications for students and post-doctoral fellows
    • M.E. Gluck University-industry relationships in the life sciences: implications for students and post-doctoral fellows Res. Policy 16 1987 327 336
    • (1987) Res. Policy , vol.16 , pp. 327-336
    • Gluck, M.E.1
  • 41
    • 79955595854 scopus 로고    scopus 로고
    • Reflections on the innovative medicines initiative
    • M. Goldman Reflections on the innovative medicines initiative Nat. Rev. Drug Discov. 10 2011 321 322
    • (2011) Nat. Rev. Drug Discov. , vol.10 , pp. 321-322
    • Goldman, M.1
  • 42
    • 84922917237 scopus 로고    scopus 로고
    • The Joint European Compound Library: boosting precompetitive research
    • J. Besnard The Joint European Compound Library: boosting precompetitive research Drug Discov. Today 2014 10.1016/j.drudis.2014.08.014
    • (2014) Drug Discov. Today
    • Besnard, J.1
  • 43
    • 84865246976 scopus 로고    scopus 로고
    • Taking open innovation to the molecular level - strengths and limitations
    • B. Zdrazil Taking open innovation to the molecular level - strengths and limitations Mol. Inf. 31 2012 528 535
    • (2012) Mol. Inf. , vol.31 , pp. 528-535
    • Zdrazil, B.1
  • 44
    • 78650847770 scopus 로고    scopus 로고
    • Selective inhibition of BET bromodomains
    • P. Filippakopoulos Selective inhibition of BET bromodomains Nature 468 2010 1067 1073
    • (2010) Nature , vol.468 , pp. 1067-1073
    • Filippakopoulos, P.1
  • 45
    • 84890472772 scopus 로고    scopus 로고
    • Public-private partnerships to revitalize psychiatric drug discovery
    • L.S. Brady, and W.Z. Potter Public-private partnerships to revitalize psychiatric drug discovery Expert Opin. Drug Discov. 9 2014 1 8
    • (2014) Expert Opin. Drug Discov. , vol.9 , pp. 1-8
    • Brady, L.S.1    Potter, W.Z.2
  • 46
    • 84922916700 scopus 로고    scopus 로고
    • The Pistoia alliance controlled substance compliance service project: from start to finish
    • D. Taylor The Pistoia alliance controlled substance compliance service project: from start to finish Drug Discov. Today 2014 10.1016/j.drudis.2014.09.021
    • (2014) Drug Discov. Today
    • Taylor, D.1
  • 47
    • 84857237851 scopus 로고    scopus 로고
    • The Innovative Medicines Initiative: a European response to the innovation challenge
    • M. Goldman The Innovative Medicines Initiative: a European response to the innovation challenge Clin. Pharmacol. Ther. 91 2012 418 425
    • (2012) Clin. Pharmacol. Ther. , vol.91 , pp. 418-425
    • Goldman, M.1
  • 48
    • 84896926686 scopus 로고    scopus 로고
    • The Innovative Medicines Initiative: a case study for new ways of working in drug R&D
    • H. Laverty, and M. Goldman The Innovative Medicines Initiative: a case study for new ways of working in drug R&D Future Med. Chem. 6 2014 489 491
    • (2014) Future Med. Chem. , vol.6 , pp. 489-491
    • Laverty, H.1    Goldman, M.2
  • 49
    • 84875166951 scopus 로고    scopus 로고
    • European Lead Factory opens for business
    • A. Mullard European Lead Factory opens for business Nat. Rev. Drug Discov. 12 2013 173 175
    • (2013) Nat. Rev. Drug Discov. , vol.12 , pp. 173-175
    • Mullard, A.1
  • 50
    • 84893334165 scopus 로고    scopus 로고
    • Precompetitive activity to address the biological data needs of drug discovery
    • B. Sidders Precompetitive activity to address the biological data needs of drug discovery Nat. Rev. Drug Discov. 13 2014 83 84
    • (2014) Nat. Rev. Drug Discov. , vol.13 , pp. 83-84
    • Sidders, B.1
  • 52
    • 84877343618 scopus 로고    scopus 로고
    • Academic-industry partnerships 2012
    • B. Hugget Academic-industry partnerships 2012 Nat. Biotechnol. 31 2013 383
    • (2013) Nat. Biotechnol. , vol.31 , pp. 383
    • Hugget, B.1
  • 53
    • 79957898111 scopus 로고    scopus 로고
    • US academic drug discovery
    • S. Frye US academic drug discovery Nat. Rev. Drug Discov. 10 2011 409 410
    • (2011) Nat. Rev. Drug Discov. , vol.10 , pp. 409-410
    • Frye, S.1
  • 54
    • 84963978327 scopus 로고    scopus 로고
    • Outcubation - where incubation meets outsourcing
    • U.A. Betz, and C.A. Tidona Outcubation - where incubation meets outsourcing Nat. Biotechnol. 33 2015 20 21
    • (2015) Nat. Biotechnol. , vol.33 , pp. 20-21
    • Betz, U.A.1    Tidona, C.A.2
  • 55
    • 79952267810 scopus 로고    scopus 로고
    • Traditional drug-discovery model ripe for reform
    • D. Cressey Traditional drug-discovery model ripe for reform Nature 471 2011 17 18
    • (2011) Nature , vol.471 , pp. 17-18
    • Cressey, D.1
  • 56
    • 84891841343 scopus 로고    scopus 로고
    • Open source drug discovery - a limited tutorial
    • R.M. Robertson Open source drug discovery - a limited tutorial Parasitology 141 2014 148 157
    • (2014) Parasitology , vol.141 , pp. 148-157
    • Robertson, R.M.1
  • 57
    • 80052698379 scopus 로고    scopus 로고
    • Open source drug discovery - a new paradigm of collaborative research in tuberculosis drug development
    • A. Bhardwaj Open source drug discovery - a new paradigm of collaborative research in tuberculosis drug development Tuberculosis 91 2011 479 486
    • (2011) Tuberculosis , vol.91 , pp. 479-486
    • Bhardwaj, A.1
  • 58
    • 80052396428 scopus 로고    scopus 로고
    • Drugs for neglected diseases initiative model of drug development for neglected diseases: current status and future challenges
    • J.R. Ioset, and S. Chang Drugs for neglected diseases initiative model of drug development for neglected diseases: current status and future challenges Future Med. Chem. 3 2011 1361 1371
    • (2011) Future Med. Chem. , vol.3 , pp. 1361-1371
    • Ioset, J.R.1    Chang, S.2
  • 59
    • 77951427922 scopus 로고    scopus 로고
    • Can open-source drug R&D repower pharmaceutical innovation?
    • B. Munos Can open-source drug R&D repower pharmaceutical innovation? Clin. Pharmacol. Ther. 87 2010 534 536
    • (2010) Clin. Pharmacol. Ther. , vol.87 , pp. 534-536
    • Munos, B.1
  • 60
    • 84899065045 scopus 로고    scopus 로고
    • The successes and challenges of open-source biopharmaceutical innovation
    • M. Allarakhia The successes and challenges of open-source biopharmaceutical innovation Expert Opin. Drug Discov. 9 2014 459 465
    • (2014) Expert Opin. Drug Discov. , vol.9 , pp. 459-465
    • Allarakhia, M.1
  • 61
    • 84908544554 scopus 로고    scopus 로고
    • Use of crowdsourcing for cancer clinical trial development
    • A. Leiter Use of crowdsourcing for cancer clinical trial development J. Natl. Cancer Inst. 106 2014 1 3
    • (2014) J. Natl. Cancer Inst. , vol.106 , pp. 1-3
    • Leiter, A.1
  • 62
    • 84908374360 scopus 로고    scopus 로고
    • Opening up clinical study design to the long tail
    • T. Sablinski Opening up clinical study design to the long tail Sci. Trans. Med. 6 2014 256ed19
    • (2014) Sci. Trans. Med. , vol.6 , pp. 256ed19
    • Sablinski, T.1
  • 63
    • 84907569947 scopus 로고    scopus 로고
    • Development assistance for neglected tropical diseases: progress since 2009
    • B.H. Liese Development assistance for neglected tropical diseases: progress since 2009 Int. Health 6 2014 162 171
    • (2014) Int. Health , vol.6 , pp. 162-171
    • Liese, B.H.1
  • 64
    • 84910665766 scopus 로고    scopus 로고
    • Crowdfunding drug development: the state of play in oncology and rare diseases
    • N. Dragojlovic, and L.D. Lynd Crowdfunding drug development: the state of play in oncology and rare diseases Drug. Discov. Today 19 2014 1775 1780
    • (2014) Drug. Discov. Today , vol.19 , pp. 1775-1780
    • Dragojlovic, N.1    Lynd, L.D.2
  • 67
    • 44649101006 scopus 로고    scopus 로고
    • Do people mix at mixers? Structure, homophily, and the life of the party
    • P. Ingram, and M.W. Morris Do people mix at mixers? Structure, homophily, and the life of the party Admin. Sci. Quart. 52 2007 558 585
    • (2007) Admin. Sci. Quart. , vol.52 , pp. 558-585
    • Ingram, P.1    Morris, M.W.2
  • 68
    • 84877765675 scopus 로고    scopus 로고
    • Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer
    • A.A. Margolin Systematic analysis of challenge-driven improvements in molecular prognostic models for breast cancer Sci. Transl. Med. 5 2013 181re1
    • (2013) Sci. Transl. Med. , vol.5 , pp. 181re1
    • Margolin, A.A.1
  • 69
  • 70
    • 79953700266 scopus 로고    scopus 로고
    • Grants4Targets - an innovative approach to translate ideas from basic research into novel drugs
    • M. Lessl Grants4Targets - an innovative approach to translate ideas from basic research into novel drugs Drug Discov. Today 16 2011 288 292
    • (2011) Drug Discov. Today , vol.16 , pp. 288-292
    • Lessl, M.1
  • 71
    • 84925285697 scopus 로고    scopus 로고
    • Grants4Targets: an open innovation initiative to foster drug discovery collaborations
    • H. Dorsch Grants4Targets: an open innovation initiative to foster drug discovery collaborations Nat. Rev. Drug Discov. 14 2015 74 76
    • (2015) Nat. Rev. Drug Discov. , vol.14 , pp. 74-76
    • Dorsch, H.1
  • 72
    • 84894094150 scopus 로고    scopus 로고
    • Open innovation drug discovery (OIDD): a potential path to novel therapeutic chemical space
    • M. Alvim-Gaston Open innovation drug discovery (OIDD): a potential path to novel therapeutic chemical space Curr. Top. Med. Chem. 14 2014 294 303
    • (2014) Curr. Top. Med. Chem. , vol.14 , pp. 294-303
    • Alvim-Gaston, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.