Epigenetic silencing of miR-708 enhances NF-κB signaling in chronic lymphocytic leukemia

International Journal of Cancer

Volumn 137, Issue 6, 2015, Pages 1352-1361

  Baer, Constance ^a   Oakes, Christopher C ^a   Ruppert, Amy S ^b   Claus, Rainer ^a,c   Kim Wanner, Soo Zin ^a   Mertens, Daniel ^a,d   Zenz, Thorsten ^a,e   Stilgenbauer, Stephan ^d   Byrd, John C ^b   Plass, Christoph ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b THE OHIO STATE UNIVERSITY WEXNER MEDICAL CENTER   (United States)

^c UNIVERSITY OF FREIBURG   (Germany)

^d UNIVERSITY OF ULM   (Germany)

^e UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

DNA methylation; epigenetics; IKK ; microRNA; miR 708; NF B

Indexed keywords

I KAPPA B ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MICRORNA; MICRORNA 708; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; I KAPPA B KINASE; MIRN708 MICRORNA, HUMAN;

3' UNTRANSLATED REGION; ARTICLE; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DNA METHYLATION; ENHANCER REGION; ENZYME REGULATION; EPIGENETICS; GENE SILENCING; GENE TARGETING; HUMAN; HUMAN CELL; LUCIFERASE ASSAY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; CELL LINE; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; HEK293 CELL LINE; PHOSPHORYLATION; PHYSIOLOGY; PROMOTER REGION;

3' UNTRANSLATED REGIONS; CELL LINE; DNA METHYLATION; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HEK293 CELLS; HUMANS; I-KAPPA B KINASE; LEUKEMIA, LYMPHOCYTIC, CHRONIC, B-CELL; MICRORNAS; NF-KAPPA B; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; SIGNAL TRANSDUCTION;

EID: 84936845675     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.29491     Document Type: Article

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