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Volumn 30, Issue 7, 2015, Pages 1653-1664

Relationship between diminished ovarian reserve and mitochondrial biogenesis in cumulus cells

Author keywords

cumulus cells; diminished ovarian reserve; mitochondria

Indexed keywords

COMPLEMENTARY DNA; DNA DIRECTED DNA POLYMERASE GAMMA; MITOCHONDRIAL DNA; MITOCHONDRIAL PROTEIN; MITOFUSIN 2; OPTIC ATROPHY 1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; TRANSCRIPTION FACTOR ASSOCIATED WITH MITOCHONDRIA; UNCLASSIFIED DRUG;

EID: 84936817547     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/dev114     Document Type: Article
Times cited : (123)

References (78)
  • 4
    • 0036153291 scopus 로고    scopus 로고
    • Predictors of poor ovarian response in in vitro fertilization: A prospective study comparing basal markers of ovarian reserve
    • Bancsi LF, Broekmans FJ, Eijkemans MJ, de Jong FH, Habbema JD, teVelde ER. Predictors of poor ovarian response in in vitro fertilization: a prospective study comparing basal markers of ovarian reserve. Fertil Steril 2002; 77:328-336.
    • (2002) Fertil Steril , vol.77 , pp. 328-336
    • Bancsi, L.F.1    Broekmans, F.J.2    Eijkemans, M.J.3    De Jong, F.H.4    Habbema, J.D.5    Tevelde, E.R.6
  • 6
    • 72749100912 scopus 로고    scopus 로고
    • The use of mitochondrial nutrients to improve the outcome of infertility treatment in older patients
    • Bentov Y, Esfandiari N, Burstein E, Casper RF. The use of mitochondrial nutrients to improve the outcome of infertility treatment in older patients. Fertil Steril 2010;93:272-275.
    • (2010) Fertil Steril , vol.93 , pp. 272-275
    • Bentov, Y.1    Esfandiari, N.2    Burstein, E.3    Casper, R.F.4
  • 7
    • 68549132328 scopus 로고    scopus 로고
    • Ovarian aging: Mechanisms and clinical consequences
    • Broekmans FJ, Soules MR, Fauser BC. Ovarian aging: mechanisms and clinical consequences. Endocr Rev 2009;30:465-493.
    • (2009) Endocr Rev , vol.30 , pp. 465-493
    • Broekmans, F.J.1    Soules, M.R.2    Fauser, B.C.3
  • 8
    • 0025124226 scopus 로고
    • Interactions between somatic cells and germ cells throughout mammalian oogenesis
    • Buccione R, Schroeder AC, Eppig JJ. Interactions between somatic cells and germ cells throughout mammalian oogenesis. Biol Reprod 1990;43: 543-547.
    • (1990) Biol Reprod , vol.43 , pp. 543-547
    • Buccione, R.1    Schroeder, A.C.2    Eppig, J.J.3
  • 9
    • 77951737783 scopus 로고    scopus 로고
    • Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations
    • Chen H, Vermulst M, Wang YE, Chomyn A, Prolla TA, McCaffery JM, Chan DC. Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations. Cell 2010;141: 280-289.
    • (2010) Cell , vol.141 , pp. 280-289
    • Chen, H.1    Vermulst, M.2    Wang, Y.E.3    Chomyn, A.4    Prolla, T.A.5    McCaffery, J.M.6    Chan, D.C.7
  • 10
    • 0036280303 scopus 로고    scopus 로고
    • DNA microarray analysis of the expression profiles of luteinized granulosa cells as a function of ovarian reserve
    • Chin KV, Seifer DB, Feng B, Lin Y, Shih WC. DNA microarray analysis of the expression profiles of luteinized granulosa cells as a function of ovarian reserve. Fertil Steril 2002;77:1214-1218.
    • (2002) Fertil Steril , vol.77 , pp. 1214-1218
    • Chin, K.V.1    Seifer, D.B.2    Feng, B.3    Lin, Y.4    Shih, W.C.5
  • 12
    • 36348972882 scopus 로고    scopus 로고
    • Association between human oocyte developmental competence and expression levels of some cumulus genes
    • Cillo F, Brevini TA, Antonini S, Paffoni A, Ragni G, Gandolfi F. Association between human oocyte developmental competence and expression levels of some cumulus genes. Reproduction 2007;134:645-650.
    • (2007) Reproduction , vol.134 , pp. 645-650
    • Cillo, F.1    Brevini, T.A.2    Antonini, S.3    Paffoni, A.4    Ragni, G.5    Gandolfi, F.6
  • 13
    • 84880144874 scopus 로고    scopus 로고
    • The activity and copy number of mitochondrial DNA in ovine oocytes throughout oogenesis in vivo and during oocyte maturation in vitro
    • Cotterill M, Harris SE, Collado Fernandez E, Lu J, Huntriss JD, Campbell BK, Picton HM. The activity and copy number of mitochondrial DNA in ovine oocytes throughout oogenesis in vivo and during oocyte maturation in vitro. Mol Hum Reprod 2013;19:444-450.
    • (2013) Mol Hum Reprod , vol.19 , pp. 444-450
    • Cotterill, M.1    Harris, S.E.2    Collado Fernandez, E.3    Lu, J.4    Huntriss, J.D.5    Campbell, B.K.6    Picton, H.M.7
  • 15
    • 33846096853 scopus 로고    scopus 로고
    • The role of mitochondrial function in the oocyte and embryo
    • Dumollard R, Duchen M, Carroll J. The role of mitochondrial function in the oocyte and embryo. Curr Top Dev Biol 2007;77:21-49.
    • (2007) Curr Top Dev Biol , vol.77 , pp. 21-49
    • Dumollard, R.1    Duchen, M.2    Carroll, J.3
  • 16
    • 79960622851 scopus 로고    scopus 로고
    • The association of reproductive senescence with mitochondrial quantity, function, and DNA integrity in human oocytes at different stages of maturation
    • Duran HE, Simsek-Duran F, Oehninger SC, Jones HW Jr, Castora FJ. The association of reproductive senescence with mitochondrial quantity, function, and DNA integrity in human oocytes at different stages of maturation. Fertil Steril 2011;96:384-388.
    • (2011) Fertil Steril , vol.96 , pp. 384-388
    • Duran, H.E.1    Simsek-Duran, F.2    Oehninger, S.C.3    Jones, H.W.4    Castora, F.J.5
  • 17
    • 0031753890 scopus 로고    scopus 로고
    • Genetics of oocyte ageing
    • Eichenlaub-Ritter U. Genetics of oocyte ageing. Maturitas 1998;30: 143-169.
    • (1998) Maturitas , vol.30 , pp. 143-169
    • Eichenlaub-Ritter, U.1
  • 19
    • 84876308017 scopus 로고    scopus 로고
    • Caspase 9 is constitutively activated in mouse oocytes and plays a key role in oocyte elimination during meiotic prophase progression
    • Ene AC, Park S, EdelmannW, Taketo T. Caspase 9 is constitutively activated in mouse oocytes and plays a key role in oocyte elimination during meiotic prophase progression. Dev Biol 2013;377:213-223.
    • (2013) Dev Biol , vol.377 , pp. 213-223
    • Ene, A.C.1    Park, S.2    Edelmann, W.3    Taketo, T.4
  • 20
    • 0037022596 scopus 로고    scopus 로고
    • The mammalian oocyte orchestrates the rate of ovarian follicular development
    • Eppig JJ, Wigglesworth K, Pendola FL. The mammalian oocyte orchestrates the rate of ovarian follicular development. Proc Natl Acad Sci U S A 2002; 99:2890-2894.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 2890-2894
    • Eppig, J.J.1    Wigglesworth, K.2    Pendola, F.L.3
  • 22
    • 84864408997 scopus 로고    scopus 로고
    • Genomic assessment of human cumulus cell marker genes as predictors of oocyte developmental competence: Impact of various experimental factors
    • Feuerstein P, Puard V, Chevalier C, Teusan R, Cadoret V, Guerif F, Houlgatte R, Royere D. Genomic assessment of human cumulus cell marker genes as predictors of oocyte developmental competence: impact of various experimental factors. PLoS One 2012;7:e40449.
    • (2012) PLoS One , vol.7 , pp. e40449
    • Feuerstein, P.1    Puard, V.2    Chevalier, C.3    Teusan, R.4    Cadoret, V.5    Guerif, F.6    Houlgatte, R.7    Royere, D.8
  • 25
    • 40049087997 scopus 로고    scopus 로고
    • Oocyte-secreted factors: Regulators of cumulus cell function and oocyte quality
    • Gilchrist RB, Lane M, Thompson JG. Oocyte-secreted factors: regulators of cumulus cell function and oocyte quality. Hum Reprod Update 2008; 14:159-177.
    • (2008) Hum Reprod Update , vol.14 , pp. 159-177
    • Gilchrist, R.B.1    Lane, M.2    Thompson, J.G.3
  • 28
    • 44449091434 scopus 로고    scopus 로고
    • Identification of differentially expressed markers in human follicular cells associated with competent oocytes
    • Hamel M, Dufort I, Robert C, Gravel C, Leveille MC, Leader A, Sirard MA. Identification of differentially expressed markers in human follicular cells associated with competent oocytes. Hum Reprod 2008;23: 1118-1127.
    • (2008) Hum Reprod , vol.23 , pp. 1118-1127
    • Hamel, M.1    Dufort, I.2    Robert, C.3    Gravel, C.4    Leveille, M.C.5    Leader, A.6    Sirard, M.A.7
  • 29
    • 0006815297 scopus 로고    scopus 로고
    • Targeted overexpression of Bcl-2 in ovaries of transgenic mice leads to decreased follicle apoptosis, enhanced folliculogenesis, and increased germ cell tumorigenesis
    • Hsu SY, Lai RJ, Finegold M, Hsueh AJ. Targeted overexpression of Bcl-2 in ovaries of transgenic mice leads to decreased follicle apoptosis, enhanced folliculogenesis, and increased germ cell tumorigenesis. Endocrinology 1996;137:4837-4843.
    • (1996) Endocrinology , vol.137 , pp. 4837-4843
    • Hsu, S.Y.1    Lai, R.J.2    Finegold, M.3    Hsueh, A.J.4
  • 30
    • 84923229423 scopus 로고    scopus 로고
    • Endometriosis may be associated with mitochondrial dysfunction in cumulus cells from subjects undergoing in vitro fertilization-intracytoplasmic sperm injection, as reflected by decreased adenosine triphosphate production
    • Hsu AL, Townsend PM, Oehninger S, Castora FJ. Endometriosis may be associated with mitochondrial dysfunction in cumulus cells from subjects undergoing in vitro fertilization-intracytoplasmic sperm injection, as reflected by decreased adenosine triphosphate production. Fertil Steril 2015;103:347-352 e1.
    • (2015) Fertil Steril , vol.103 , pp. 347-352e1
    • Hsu, A.L.1    Townsend, P.M.2    Oehninger, S.3    Castora, F.J.4
  • 31
    • 21244480038 scopus 로고    scopus 로고
    • Apoptosis in the ovary: Molecular mechanisms
    • Hussein MR. Apoptosis in the ovary: molecular mechanisms. Hum Reprod Update 2005;11:162-177.
    • (2005) Hum Reprod Update , vol.11 , pp. 162-177
    • Hussein, M.R.1
  • 32
    • 79957566613 scopus 로고    scopus 로고
    • Effect of maternal age on mitochondrial DNA copy number, ATP content and IVF outcome of bovine oocytes
    • Iwata H, Goto H, Tanaka H, Sakaguchi Y, Kimura K, Kuwayama T, Monji Y. Effect of maternal age on mitochondrial DNA copy number, ATP content and IVF outcome of bovine oocytes. Reprod Fertil Dev 2011;23:424-432.
    • (2011) Reprod Fertil Dev , vol.23 , pp. 424-432
    • Iwata, H.1    Goto, H.2    Tanaka, H.3    Sakaguchi, Y.4    Kimura, K.5    Kuwayama, T.6    Monji, Y.7
  • 33
    • 33847663890 scopus 로고    scopus 로고
    • Characterization of mitochondrial replication and transcription control during rat early development in vivo and in vitro
    • Kameyama Y, Filion F, Yoo JG, Smith LC. Characterization of mitochondrial replication and transcription control during rat early development in vivo and in vitro. Reproduction 2007;133:423-432.
    • (2007) Reproduction , vol.133 , pp. 423-432
    • Kameyama, Y.1    Filion, F.2    Yoo, J.G.3    Smith, L.C.4
  • 34
    • 84922106699 scopus 로고    scopus 로고
    • Simultaneous assessment of aneuploidy, polymorphisms, and mitochondrial DNA content in human polar bodies and embryos with the use of a novel microarray platform
    • Konstantinidis M, Alfarawati S, Hurd D, Paolucci M, Shovelton J, Fragouli E, Wells D. Simultaneous assessment of aneuploidy, polymorphisms, and mitochondrial DNA content in human polar bodies and embryos with the use of a novel microarray platform. Fertil Steril 2014;102: 1385-1392.
    • (2014) Fertil Steril , vol.102 , pp. 1385-1392
    • Konstantinidis, M.1    Alfarawati, S.2    Hurd, D.3    Paolucci, M.4    Shovelton, J.5    Fragouli, E.6    Wells, D.7
  • 35
    • 84899458647 scopus 로고    scopus 로고
    • The association of mitochondrial potential and copy number with pig oocyte maturation and developmental potential
    • Lee SK, Zhao MH, Kwon JW, Li YH, Lin ZL, Jin YX, Kim NH, Cui XS. The association of mitochondrial potential and copy number with pig oocyte maturation and developmental potential. J Reprod Dev 2014;60:128-135.
    • (2014) J Reprod Dev , vol.60 , pp. 128-135
    • Lee, S.K.1    Zhao, M.H.2    Kwon, J.W.3    Li, Y.H.4    Lin, Z.L.5    Jin, Y.X.6    Kim, N.H.7    Cui, X.S.8
  • 39
    • 84864345842 scopus 로고    scopus 로고
    • Regulation of mitochondrial DNA accumulation during oocyte growth and meiotic maturation in the mouse
    • Mahrous E, Yang Q, Clarke HJ. Regulation of mitochondrial DNA accumulation during oocyte growth and meiotic maturation in the mouse. Reproduction 2012;144:177-185.
    • (2012) Reproduction , vol.144 , pp. 177-185
    • Mahrous, E.1    Yang, Q.2    Clarke, H.J.3
  • 43
  • 44
    • 0037424239 scopus 로고    scopus 로고
    • Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis
    • Olichon A, Baricault L, Gas N, Guillou E, Valette A, Belenguer P, Lenaers G. Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis. J Biol Chem 2003;278:7743-7746.
    • (2003) J Biol Chem , vol.278 , pp. 7743-7746
    • Olichon, A.1    Baricault, L.2    Gas, N.3    Guillou, E.4    Valette, A.5    Belenguer, P.6    Lenaers, G.7
  • 45
    • 84902662187 scopus 로고    scopus 로고
    • Mitochondrial SIRT3 and its target glutamate dehydrogenase are altered in follicular cells of women with reduced ovarian reserve or advanced maternal age
    • Pacella-Ince L, Zander-Fox DL, Lan M. Mitochondrial SIRT3 and its target glutamate dehydrogenase are altered in follicular cells of women with reduced ovarian reserve or advanced maternal age. Hum Reprod 2014; 29:1490-1499.
    • (2014) Hum Reprod , vol.29 , pp. 1490-1499
    • Pacella-Ince, L.1    Zander-Fox, D.L.2    Lan, M.3
  • 47
    • 0023518420 scopus 로고
    • Amounts of mitochondrial DNA and abundance of some mitochondrial gene transcripts in early mouse embryos
    • Piko L, Taylor KD. Amounts of mitochondrial DNA and abundance of some mitochondrial gene transcripts in early mouse embryos. Dev Biol 1987; 123:364-374.
    • (1987) Dev Biol , vol.123 , pp. 364-374
    • Piko, L.1    Taylor, K.D.2
  • 48
    • 0032549811 scopus 로고    scopus 로고
    • A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
    • Puigserver P, Wu Z, Park CW, Graves R, Wright M, Spiegelman BM. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 1998;92:829-839.
    • (1998) Cell , vol.92 , pp. 829-839
    • Puigserver, P.1    Wu, Z.2    Park, C.W.3    Graves, R.4    Wright, M.5    Spiegelman, B.M.6
  • 49
    • 0029118052 scopus 로고
    • Ablation of bcl-2 gene expression decreases the numbers of oocytes and primordial follicles established in the post-natal female mouse gonad
    • Ratts VS, Flaws JA, Kolp R, Sorenson CM, Tilly JL. Ablation of bcl-2 gene expression decreases the numbers of oocytes and primordial follicles established in the post-natal female mouse gonad. Endocrinology 1995; 136:3665-3668.
    • (1995) Endocrinology , vol.136 , pp. 3665-3668
    • Ratts, V.S.1    Flaws, J.A.2    Kolp, R.3    Sorenson, C.M.4    Tilly, J.L.5
  • 51
    • 32944459568 scopus 로고    scopus 로고
    • Mitochondrial content reflects oocyte variability and fertilization outcome
    • Santos TA, El Shourbagy S, St John JC. Mitochondrial content reflects oocyte variability and fertilization outcome. Fertil Steril 2006;85:584-591.
    • (2006) Fertil Steril , vol.85 , pp. 584-591
    • Santos, T.A.1    El Shourbagy, S.2    St John, J.C.3
  • 53
    • 0027326687 scopus 로고
    • A prospective evaluation of clomiphene citrate challenge test screening of the general infertility population
    • Scott RT, Leonardi MR, Hofmann GE, Illions EH, Neal GS, Navot D. A prospective evaluation of clomiphene citrate challenge test screening of the general infertility population. Obstet Gynecol 1993;82:539-544.
    • (1993) Obstet Gynecol , vol.82 , pp. 539-544
    • Scott, R.T.1    Leonardi, M.R.2    Hofmann, G.E.3    Illions, E.H.4    Neal, G.S.5    Navot, D.6
  • 54
    • 0036843859 scopus 로고    scopus 로고
    • Mitochondrial deletions in luteinized granulosa cells as a function of age in women undergoing in vitro fertilization
    • Seifer DB, DeJesus V, Hubbard K. Mitochondrial deletions in luteinized granulosa cells as a function of age in women undergoing in vitro fertilization. Fertil Steril 2002;78:1046-1048.
    • (2002) Fertil Steril , vol.78 , pp. 1046-1048
    • Seifer, D.B.1    Dejesus, V.2    Hubbard, K.3
  • 55
    • 34247531936 scopus 로고    scopus 로고
    • Fertilization, embryo development, and clinical outcome of immature oocytes from stimulated intracytoplasmic sperm injection cycles
    • Shu Y, Gebhardt J, Watt J, Lyon J, Dasig D, Behr B. Fertilization, embryo development, and clinical outcome of immature oocytes from stimulated intracytoplasmic sperm injection cycles. Fertil Steril 2007; 87:1022-1027.
    • (2007) Fertil Steril , vol.87 , pp. 1022-1027
    • Shu, Y.1    Gebhardt, J.2    Watt, J.3    Lyon, J.4    Dasig, D.5    Behr, B.6
  • 57
    • 84895560707 scopus 로고    scopus 로고
    • The control of mtDNA replication during differentiation and development
    • St John J. The control of mtDNA replication during differentiation and development. Biochim Biophys Acta 2013;1840:1345-1354.
    • (2013) Biochim Biophys Acta , vol.1840 , pp. 1345-1354
    • St John, J.1
  • 58
    • 77955593985 scopus 로고    scopus 로고
    • Mitochondrial DNA transmission, replication and inheritance: A journey from the gamete through the embryo and into offspring and embryonic stem cells
    • St John JC, Facucho-Oliveira J, Jiang Y, Kelly R, Salah R. Mitochondrial DNA transmission, replication and inheritance: a journey from the gamete through the embryo and into offspring and embryonic stem cells. Hum Reprod Update 2010;16:488-509.
    • (2010) Hum Reprod Update , vol.16 , pp. 488-509
    • St John, J.C.1    Facucho-Oliveira, J.2    Jiang, Y.3    Kelly, R.4    Salah, R.5
  • 59
    • 84943366781 scopus 로고    scopus 로고
    • MTDNA mutations variously impact mtDNA maintenance throughout the human embryofetal development
    • (Epub ahead of print)
    • Steffann J, Monnot S, Bonnefont JP. mtDNA mutations variously impact mtDNA maintenance throughout the human embryofetal development. Clin Genet 2014. doi:10. 1111/cge. 12557. (Epub ahead of print).
    • (2014) Clin Genet
    • Steffann, J.1    Monnot, S.2    Bonnefont, J.P.3
  • 60
    • 0034252008 scopus 로고    scopus 로고
    • Quantification of mtDNA in single oocytes, polar bodies and subcellular components by real-time rapid cycle fluorescence monitored PCR
    • Steuerwald N, Barritt JA, Adler R, Malter H, Schimmel T, Cohen J, Brenner CA. Quantification of mtDNA in single oocytes, polar bodies and subcellular components by real-time rapid cycle fluorescence monitored PCR. Zygote 2000;8:209-215.
    • (2000) Zygote , vol.8 , pp. 209-215
    • Steuerwald, N.1    Barritt, J.A.2    Adler, R.3    Malter, H.4    Schimmel, T.5    Cohen, J.6    Brenner, C.A.7
  • 61
    • 77956095537 scopus 로고    scopus 로고
    • Mitochondria and cell death: Outer membrane permeabilization and beyond
    • Tait SW, Green DR. Mitochondria and cell death: outer membrane permeabilization and beyond. Nat Rev Mol Cell Biol 2010;11:621-632.
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 621-632
    • Tait, S.W.1    Green, D.R.2
  • 62
    • 0036232803 scopus 로고    scopus 로고
    • The variability of female reproductive ageing
    • te Velde ER, Pearson PL. The variability of female reproductive ageing. Hum Reprod Update 2002;8:141-154.
    • (2002) Hum Reprod Update , vol.8 , pp. 141-154
    • Te Velde, E.R.1    Pearson, P.L.2
  • 63
    • 21544471197 scopus 로고    scopus 로고
    • Molecular control of mitochondrial function in preimplantation mouse embryos
    • Thundathil J, Filion F, Smith LC. Molecular control of mitochondrial function in preimplantation mouse embryos. Mol Reprod Dev 2005;71:405-413.
    • (2005) Mol Reprod Dev , vol.71 , pp. 405-413
    • Thundathil, J.1    Filion, F.2    Smith, L.C.3
  • 66
    • 79961207245 scopus 로고    scopus 로고
    • Mitochondrial function in the human oocyte and embryo and their role in developmental competence
    • Van Blerkom J. Mitochondrial function in the human oocyte and embryo and their role in developmental competence. Mitochondrion 2011;11: 797-813.
    • (2011) Mitochondrion , vol.11 , pp. 797-813
    • Van Blerkom, J.1
  • 67
    • 0028918729 scopus 로고
    • ATP content of human oocytes and developmental potential and outcome after in-vitro fertilization and embryo transfer
    • Van Blerkom J, Davis PW, Lee J. ATP content of human oocytes and developmental potential and outcome after in-vitro fertilization and embryo transfer. Hum Reprod 1995;10:415-424.
    • (1995) Hum Reprod , vol.10 , pp. 415-424
    • Van Blerkom, J.1    Davis, P.W.2    Lee, J.3
  • 68
    • 0031728072 scopus 로고    scopus 로고
    • Mitochondrial transfer between oocytes: Potential applications of mitochondrial donation and the issue of heteroplasmy
    • Van Blerkom J, Sinclair J, Davis P. Mitochondrial transfer between oocytes: potential applications of mitochondrial donation and the issue of heteroplasmy. Hum Reprod 1998;13:2857-2868.
    • (1998) Hum Reprod , vol.13 , pp. 2857-2868
    • Van Blerkom, J.1    Sinclair, J.2    Davis, P.3
  • 70
  • 76
    • 84905487367 scopus 로고    scopus 로고
    • Clinical utilisation of a rapid low-pass whole genome sequencing technique for the diagnosis of aneuploidy in human embryos prior to implantation
    • Wells D, Kaur K, Grifo J, Glassner M, Taylor JC, Fragouli E, Munne S. Clinical utilisation of a rapid low-pass whole genome sequencing technique for the diagnosis of aneuploidy in human embryos prior to implantation. J Med Genet 2014;51:553-562.
    • (2014) J Med Genet , vol.51 , pp. 553-562
    • Wells, D.1    Kaur, K.2    Grifo, J.3    Glassner, M.4    Taylor, J.C.5    Fragouli, E.6    Munne, S.7
  • 78
    • 34447321569 scopus 로고    scopus 로고
    • Low mitochondrial DNA and ATP contents contribute to the absence of birefringent spindle imaged with PolScope in in vitro matured human oocytes
    • Zeng HT, Ren Z, Yeung WS, Shu YM, Xu YW, Zhuang GL, Liang XY. Low mitochondrial DNA and ATP contents contribute to the absence of birefringent spindle imaged with PolScope in in vitro matured human oocytes. Hum Reprod 2007;22:1681-1686.
    • (2007) Hum Reprod , vol.22 , pp. 1681-1686
    • Zeng, H.T.1    Ren, Z.2    Yeung, W.S.3    Shu, Y.M.4    Xu, Y.W.5    Zhuang, G.L.6    Liang, X.Y.7


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