Miscarriage risk for IVF pregnancies in poor responders to ovarian hyperstimulation

Reproductive BioMedicine Online

Volumn 20, Issue 2, 2010, Pages 191-200

  Haadsma, Maaike L ^a   Groen, Henk ^a   Mooij, Thea M ^b   Burger, Curt W ^c   Broekmans, Frank J M ^d   Lambalk, Cornelis B ^e   Van Leeuwen, Flora E ^b   Hoek, Annemiek ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c ERASMUS MEDICAL CENTER   (Netherlands)

^d UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^e VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

IVF; Miscarriage; Ovarian reserve; Poor response; Pregnancy loss

Indexed keywords

ADULT; ARTICLE; CONTROLLED STUDY; DEMOGRAPHY; DISEASE ASSOCIATION; EMBRYO TRANSFER; FEMALE; FEMALE INFERTILITY; FERTILIZATION IN VITRO; HUMAN; HUMAN CELL; LIVE BIRTH; MAJOR CLINICAL STUDY; MATERNAL AGE; OOCYTE RETRIEVAL; OUTCOME ASSESSMENT; OVARY HYPERSTIMULATION; PATIENT INFORMATION; PATIENT SELECTION; PREGNANCY; PREGNANCY OUTCOME; RETROSPECTIVE STUDY; RISK FACTOR; SPONTANEOUS ABORTION; TREATMENT RESPONSE;

EID: 77649219016     PISSN: 14726483     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rbmo.2009.11.005     Document Type: Article

References (63)

1. Abdalla, H., Thum, M.Y., 2004. An elevated basal FSH reflects a quantitative rather than qualitative decline of the ovarian reserve. Hum. Reprod. 19, 893-898.
2. Baird, D.T., Collins, J., Egozcue, J., et al., 2005. Fertility and ageing. Hum. Reprod. Update 11, 261-276.
3. Bancsi, L.F., Broekmans, F.J., Looman, C.W., et al., 2004. Impact of repeated antral follicle counts on the prediction of poor ovarian response in women undergoing in vitro fertilization. Fertil. Steril. 81, 35-41.
4. Block, E., 1952. Quantitative morphological investigations of the follicular system in women; variations at different ages. Acta Anat. 14, 108-123.
5. Boue, A., Boue, J., Gropp, A., 1985. Cytogenetics of pregnancy wastage. Adv. Hum. Genet. 14, 1-57.
6. Brigham, S.A., Conlon, C., Farquharson, R.G., 1999. A longitudinal study of pregnancy outcome following idiopathic recurrent miscarriage. Hum. Reprod. 14, 2868-2871.
7. Broekmans, F.J., Kwee, J., Hendriks, D.J., 2006. A systematic review of tests predicting ovarian reserve and IVF outcome. Hum. Reprod. Update 12, 685-718.
8. de Boer, E.J., den Tonkelaar, I., Te Velde, E.R., et al., 2003. Increased risk of early menopausal transition and natural menopause after poor response at first IVF treatment. Hum. Reprod. 18, 1544-1552.
9. de Koning, C.H., Benjamins, T., Harms, P., 2006. The distribution of FSH receptor isoforms is related to basal FSH levels in subfertile women with normal menstrual cycles. Hum. Reprod. 21, 443-446.
10. de Koning, C.H., Popp-Snijders, C., Martens, F., et al., 2000. Falsely elevated follicle-stimulating hormone levels in women with regular menstrual cycles due to interference in immunoradiometric assay. J. Assist. Reprod. Genet. 17, 457-459.
11. de Sutter, P., Dhont, M., 2003. Poor response after hormonal stimulation for in vitro fertilization is not related to ovarian aging. Fertil. Steril. 79, 1294-1298.
12. Dursun, P., Gultekin, M., Yuce, K., et al., 2005. What is the underlying aneuploidy associated cause of with increasing maternal age? Is it associated with elevated levels of gonadotropins? Med. Hypotheses 66, 143-147.
13. Eichenlaub-Ritter, U., 1998. Genetics of oocyte ageing. Maturitas 30, 143-169.
14. Elter, K., Kavak, Z.N., Gokaslan, H., et al., 2005. Antral follicle assessment after down-regulation may be a useful tool for predicting pregnancy loss in in vitro fertilization pregnancies. Gynecol. Endocrinol. 21, 33-37.
15. Gaulden, M. E., 1992. Maternal age effect: the enigma of Down syndrome and other trisomic conditions. Mutat. Res. 296, 69-88.
16. Gosden, R.G., Faddy, M.J., 1994. Ovarian aging, follicular depletion, and steroidogenesis. Exp. Gerontol. 29, 265-274.
17. Gougeon, A., 1996. Regulation of ovarian follicular development in primates: facts and hypotheses. Endocr. Rev. 17, 121-155.
18. Gougeon, A., Ecochard, R., Thalabard, J.C., 1994. Age-related changes of the population of human ovarian follicles: increase in the disappearance rate of non-growing and early-growing follicles in aging women. Biol. Reprod. 50, 653-663.
19. Haadsma, M.L., Groen, H., Fidler, V., et al., 2008. The predictive value of ovarian reserve tests for spontaneous pregnancy in subfertile ovulatory women. Hum. Reprod. 23, 1800-1807.
20. Haadsma, M.L., Groen, H., Fidler, V., et al., 2009. The predictive value of ovarian reserve tests for miscarriage in a population of subfertile ovulatory women. Hum. Reprod. 24, 546-552.
21. Hanoch, J., Lavy, Y., Holzer, H., et al., 1998. Young low responders protected from untoward effects of reduced ovarian response. Fertil. Steril. 69, 1001-1004.
22. Hansen, K.R., Knowlton, N.S., Thyer, A.C., et al., 2008. A new model of reproductive aging: the decline in ovarian non-growing follicle number from birth to menopause. Hum. Reprod. 23, 699-708.
23. Hassold, T., Hunt, P., 2001. To err (meiotically) is human: the genesis of human aneuploidy. Nat. Rev. Genet. 2, 280-291.
24. Hassold, T., Abruzzo, M., Adkins, K., et al., 1996. Human aneuploidy: incidence, origin, and etiology. Environ. Mol. Mutagen. 28, 167-175.
25. Havryliuk, Y., Dragisic, K.G., Rosenwaks, Z., 2006. Baseline serum FSH levels in poor prognostic IVF patients: do abnormal levels predict fetal aneuploidy? Fertil. Steril. 86, S21.
26. Henderson, S.A., Edwards, R.G., et al., 1968. Chiasma frequency and maternal age in mammals. Nature 218, 22-28.
27. Hendriks, D.J., Te Velde, E.R., Looman, C.W., et al., 2008. Expected poor ovarian response in predicting cumulative pregnancy rates: a powerful tool. Reprod. Biomed. Online 17, 727-736.
28. Hunt, P.A., Hassold, T.J., 2008. Human female meiosis: what makes a good egg go bad? Trends Genet. 24, 86-93.
29. Klinkert, E.R., Broekmans, F.J., Looman, C.W., et al., 2004. A poor response in the first in vitro fertilization cycle is not necessarily related to a poor prognosis in subsequent cycles. Fertil. Steril. 81, 1247-1253.
30. Klip, H., van Leeuwen, F.E., Schats, R., et al., 2003. Risk of benign gynecological diseases and hormonal disorders according to responsiveness to ovarian stimulation in IVF: a follow-up study of 8714 women. Hum. Reprod. 18, 1951-1958.
31. Kumbak, B., Ulug, U., Erzik, B., et al., 2009. Early clinical pregnancy loss rate in poor responder patients does not change compared to age-matched normoresponders. Fertil. Steril. 91, 106-109.
32. Lambalk, C.B., de Koning, C.H., 1998. Interpretation of elevated FSH in the regular menstrual cycle. Maturitas 30, 215-220.
33. Lambers, M.J., Mager, E., Goutbeek, J., et al., 2007. Factors determining early pregnancy loss in singleton and multiple implantations. Hum. Reprod. 22, 275-279.
34. Lawson, R., El-Toukhy, T., Kassab, A., et al., 2003. Poor response to ovulation induction is a stronger predictor of early menopause than elevated basal FSH: a life table analysis. Hum. Reprod. 18, 527-533.
35. Lekamge, D.N., Barry, M., Kolo, M., et al., 2007. Anti-Mullerian hormone as a predictor of IVF outcome. Reprod. Biomed. Online 14, 602-610.
36. Levi, A.J., Raynault, M.F., Bergh, P.A., et al., 2001. Reproductive outcome in patients with diminished ovarian reserve. Fertil. Steril. 76, 666-669.
37. Lintsen, A.M., Pasker-de Jong, P.C., de Boer, E.J., et al., 2005. Effects of subfertility cause, smoking and body weight on the success rate of IVF. Hum. Reprod. 20, 1867-1875.
38. Luna, M., Grunfeld, L., Mukherjee, T., et al., 2007. Moderately elevated levels of basal follicle-stimulating hormone in young patients predict low ovarian response, but should not be used to disqualify patients from attempting in vitro fertilization. Fertil. Steril. 87, 782-787.
39. Maheshwari, A., Fowler, P., Bhattacharya, S., 2006. Assessment of ovarian reserve-should we perform tests of ovarian reserve routinely? Hum. Reprod. 21, 2729-2735.
40. Massie, J.A., Burney, R.O., Milki, A.A., et al., 2008. Basal follicle-stimulating hormone as a predictor of fetal aneuploidy. Fertil. Steril. 90, 2351-2355.
41. McTavish, K.J., Jimenez, M., Walters, K.A., et al., 2007. Rising follicle-stimulating hormone levels with age accelerate female reproductive failure. Endocrinology 148, 4432-4439.
42. Moreno, C., Ruiz, A., Simon, C., et al., 1998. Intracytoplasmic sperm injection as a routine indication in low responder patients. Hum. Reprod. 13, 2126-2129.
43. Nasseri, A., Mukherjee, T., Grifo, J.A., et al., 1999. Elevated day 3 serum follicle stimulating hormone and/or estradiol may predict fetal aneuploidy. Fertil. Steril. 71, 715-718.
44. Nikolaou, D., Templeton, A., 2004. Early ovarian ageing. Eur. J. Obstet. Gynecol. Reprod. Biol. 113, 126-133.
45. Nybo Andersen, A.M., Wohlfahrt, J., Christens, P., et al., 2000. Maternal age and fetal loss: population based register linkage study. BMJ 320, 1708-1712.
46. Quenby, S., Vince, G., Farquharson, R., et al., 2002. Recurrent miscarriage: a defect in nature's quality control? Hum. Reprod. 17, 1959-1963.
47. Rothman, K.J., Greenland, S., 1998. Introduction to stratified analysis. In: Modern Epidemiology. Lippincott-Raven, Philadelphia, pp. 256-258.
48. Sabatini, L., Zosmer, A., Hennessy, E.M., et al., 2008. Relevance of basal serum FSH to IVF outcome varies with patient age. Reprod. Biomed. Online 17, 10-19.
49. Saldeen, P., Kallen, K., Sundstrom, P., 2007. The probability of successful IVF outcome after poor ovarian response. Acta Obstet. Gynecol. Scand. 86, 457-461.
50. Shanbhag S, Aucott L, Bhattacharya S et al. 2007 Interventions for 'poor responders' to controlled ovarian hyperstimulation (COH) in in-vitro fertilisation (IVF). Cochrane Database of Systematic Reviews, CD004379.
51. Tarin, J.J., 1995. Aetiology of age-associated aneuploidy: a mechanism based on the 'free radical theory of ageing'. Hum. Reprod. 10, 1563-1565.
52. Tarlatzis, B.C., Zepiridis, L., Grimbizis, G., et al., 2003. Clinical management of low ovarian response to stimulation for IVF: a systematic review. Hum. Reprod. Update 9, 61-76.
53. Te Velde, E.R., Pearson, P.L., 2002. The variability of female reproductive ageing. Hum. Reprod. Update 8, 141-154.
54. Te Velde, E.R., Dorland, M., Broekmans, F.J., 1998. Age at menopause as a marker of reproductive ageing. Maturitas 30, 119-125.
55. Tummers, P., De Sutter, P., Dhont, M., 2003. Risk of spontaneous abortion in singleton and twin pregnancies after IVF/ICSI. Hum. Reprod. 18, 1720-1723.
56. van Blerkom, J., Antczak, M., Schrader, R., 1997. The developmental potential of the human oocyte is related to the dissolved oxygen content of follicular fluid: association with vascular endothelial growth factor levels and perifollicular blood flow characteristics. Hum. Reprod. 12, 1047-1055.
57. van der Steeg, J.W., Steures, P., Eijkemans, M.J., et al., 2007. Predictive value and clinical impact of Basal follicle-stimulating hormone in subfertile, ovulatory women. J. Clin. Endocrinol. Metab. 92, 2163-2168.
58. van Montfrans, J.M., van Hooff, M.H., Huirne, J.A., et al., 2004. Basal FSH concentrations as a marker of ovarian ageing are not related to pregnancy outcome in a general population of women over 30 years. Hum. Reprod. 19, 430-434.
59. van Rooij, I., Broekmans, F.J., Hunault, C.C., et al., 2006. Use of ovarian reserve tests for the prediction of ongoing pregnancy in couples with unexplained or mild male infertility. Reprod. Biomed. Online 12, 182-190.
60. Warburton, D., 1989. The effect of maternal age on the frequency of trisomy: change in meiosis or in utero selection? Prog. Cell Cycle Res. 311, 165-181.
61. Warburton, D., 2005. Biological aging and the etiology of aneuploidy. Cytogenet. Genome Res. 111, 266-272.
62. Winter, E., Wang, J., Davies, M.J., Norman, R., 2002. Early pregnancy loss following assisted reproductive technology treatment. Hum. Reprod. 17, 3220-3223.
63. Zhen, X.M., Qiao, J., Li, R., Wang, L.N., et al., 2008. The clinical analysis of poor ovarian response in in-vitro-fertilization embryo-transfer among Chinese couples. J. Assist. Reprod. Genet. 25, 17-22.