A self-lysis pathway that enhances the virulence of a pathogenic bacterium

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 27, 2015, Pages 8433-8438

  McFarland, Kirsty A ^a   Dolben, Emily L ^b   LeRoux, Michele ^c,d   Kambara, Tracy K ^a   Ramsey, Kathryn M ^a   Kirkpatrick, Robin L ^c   Mougous, Joseph D ^c   Hogan, Deborah A ^b   Dove, Simon L ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Cell lysis; Essential regulator; Lung colonization; Programmed cell death; Pseudomonas aeruginosa

Indexed keywords

ALPR PROTEIN; CIPROFLOXACIN; LEXA PROTEIN; PROTEIN; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; TRANSCRIPTION FACTOR;

APOPTOSIS; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL VIRULENCE; CELL ACTIVATION; CELL FUNCTION; CELL GROWTH; CELL SURVIVAL; CYTOLYSIS; DNA CLEAVAGE; DNA DAMAGE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HOST CELL; IMMUNE RESPONSE; IMMUNE SYSTEM; LUNG INFECTION; LYSIS; NONHUMAN; PATHOGENESIS; POPULATION; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SIGNAL TRANSDUCTION; AMINO ACID SEQUENCE; ANIMAL; BACTERIOLYSIS; C57BL MOUSE; FLUORESCENCE MICROSCOPY; GENE EXPRESSION REGULATION; GENETICS; MALE; METABOLISM; MICROBIAL VIABILITY; MICROBIOLOGY; MOLECULAR GENETICS; MUTATION; OPERON; PATHOGENICITY; PSEUDOMONAS INFECTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; TIME LAPSE IMAGING; VIRULENCE; WESTERN BLOTTING;

BACTERIA (MICROORGANISMS); MAMMALIA; PSEUDOMONAS AERUGINOSA;

AMINO ACID SEQUENCE; ANIMALS; BACTERIAL PROTEINS; BACTERIOLYSIS; BLOTTING, WESTERN; GENE EXPRESSION REGULATION, BACTERIAL; MALE; MICE, INBRED C57BL; MICROBIAL VIABILITY; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; MUTATION; OPERON; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; TIME-LAPSE IMAGING; TRANSCRIPTION FACTORS; VIRULENCE;

EID: 84936803316     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1506299112     Document Type: Article

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