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Volumn 195, Issue 2, 2015, Pages 726-735

Critical roles of chemoresistant effector and regulatory T cells in antitumor immunity after lymphodepleting chemotherapy

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; CYCLOPHOSPHAMIDE; ETOPOSIDE; FLUDARABINE; GEMCITABINE; PACLITAXEL; 3 METHYLCHOLANTHRENE; CYTOTOXIN; DEOXYCYTIDINE; VIDARABINE;

EID: 84936796881     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1401468     Document Type: Article
Times cited : (25)

References (57)
  • 1
    • 0020047427 scopus 로고
    • Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells
    • North, R. J. 1982. Cyclophosphamide-facilitated adoptive immunotherapy of an established tumor depends on elimination of tumor-induced suppressor T cells. J. Exp. Med. 155: 1063-1074.
    • (1982) J. Exp. Med. , vol.155 , pp. 1063-1074
    • North, R.J.1
  • 2
    • 0021247642 scopus 로고
    • Gamma-irradiation facilitates the expression of adoptive immunity against established tumors by eliminating suppressor T cells
    • North, R. J. 1984. Gamma-irradiation facilitates the expression of adoptive immunity against established tumors by eliminating suppressor T cells. Cancer Immunol. Immunother. 16: 175-181.
    • (1984) Cancer Immunol. Immunother. , vol.16 , pp. 175-181
    • North, R.J.1
  • 3
    • 84858758766 scopus 로고    scopus 로고
    • Adoptive immunotherapy for cancer: Harnessing the T cell response
    • Restifo, N. P., M. E. Dudley, and S. A. Rosenberg. 2012. Adoptive immunotherapy for cancer: harnessing the T cell response. Nat. Rev. Immunol. 12: 269-281.
    • (2012) Nat. Rev. Immunol. , vol.12 , pp. 269-281
    • Restifo, N.P.1    Dudley, M.E.2    Rosenberg, S.A.3
  • 4
    • 80053567512 scopus 로고    scopus 로고
    • Cell transfer immunotherapy for metastatic solid cancer-what clinicians need to know
    • Rosenberg, S. A. 2011. Cell transfer immunotherapy for metastatic solid cancer-what clinicians need to know. Nat. Rev. Clin. Oncol. 8: 577-585.
    • (2011) Nat. Rev. Clin. Oncol. , vol.8 , pp. 577-585
    • Rosenberg, S.A.1
  • 6
    • 0034698931 scopus 로고    scopus 로고
    • Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation
    • Goldrath, A. W., L. Y. Bogatzki, and M. J. Bevan. 2000. Naive T cells transiently acquire a memory-like phenotype during homeostasis-driven proliferation. J. Exp. Med. 192: 557-564.
    • (2000) J. Exp. Med. , vol.192 , pp. 557-564
    • Goldrath, A.W.1    Bogatzki, L.Y.2    Bevan, M.J.3
  • 7
    • 1942453326 scopus 로고    scopus 로고
    • Homeostatic expansion of T cells during immune insufficiency generates autoimmunity
    • King, C., A. Ilic, K. Koelsch, and N. Sarvetnick. 2004. Homeostatic expansion of T cells during immune insufficiency generates autoimmunity. Cell 117: 265-277.
    • (2004) Cell , vol.117 , pp. 265-277
    • King, C.1    Ilic, A.2    Koelsch, K.3    Sarvetnick, N.4
  • 8
    • 0041975925 scopus 로고    scopus 로고
    • Anti-tumor T cell response and protective immunity in mice that received sublethal irradiation and immune reconstitution
    • Ma, J., W. J. Urba, L. Si, Y. Wang, B. A. Fox, and H. M. Hu. 2003. Anti-tumor T cell response and protective immunity in mice that received sublethal irradiation and immune reconstitution. Eur. J. Immunol. 33: 2123-2132.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 2123-2132
    • Ma, J.1    Urba, W.J.2    Si, L.3    Wang, Y.4    Fox, B.A.5    Hu, H.M.6
  • 9
    • 0025784078 scopus 로고
    • Specific adoptive immunotherapy mediated by tumor-draining lymph node cells sequentially activated with anti-CD3 and IL-2
    • Yoshizawa, H., A. E. Chang, and S. Shu. 1991. Specific adoptive immunotherapy mediated by tumor-draining lymph node cells sequentially activated with anti-CD3 and IL-2. J. Immunol. 147: 729-737.
    • (1991) J. Immunol. , vol.147 , pp. 729-737
    • Yoshizawa, H.1    Chang, A.E.2    Shu, S.3
  • 10
    • 34249677872 scopus 로고    scopus 로고
    • Adoptive transfer of tumor-primed, in vitro-activated, CD4+ T effector cells (TEs) combined with CD8+ TEs provides intratumoral TE proliferation and synergistic antitumor response
    • Wang, L. X., S. Shu, M. L. Disis, and G. E. Plautz. 2007. Adoptive transfer of tumor-primed, in vitro-activated, CD4+ T effector cells (TEs) combined with CD8+ TEs provides intratumoral TE proliferation and synergistic antitumor response. Blood 109: 4865-4876.
    • (2007) Blood , vol.109 , pp. 4865-4876
    • Wang, L.X.1    Shu, S.2    Disis, M.L.3    Plautz, G.E.4
  • 12
    • 0021888316 scopus 로고
    • Adoptive immunotherapy of newly induced murine sarcomas
    • Shu, S. Y., and S. A. Rosenberg. 1985. Adoptive immunotherapy of newly induced murine sarcomas. Cancer Res. 45: 1657-1662.
    • (1985) Cancer Res. , vol.45 , pp. 1657-1662
    • Shu, S.Y.1    Rosenberg, S.A.2
  • 13
    • 26844577145 scopus 로고    scopus 로고
    • Both regulatory T cells and antitumor effector T cells are primed in the same draining lymph nodes during tumor progression
    • Hiura, T., H. Kagamu, S. Miura, A. Ishida, H. Tanaka, J. Tanaka, F. Gejyo, and H. Yoshizawa. 2005. Both regulatory T cells and antitumor effector T cells are primed in the same draining lymph nodes during tumor progression. J. Immunol. 175: 5058-5066.
    • (2005) J. Immunol. , vol.175 , pp. 5058-5066
    • Hiura, T.1    Kagamu, H.2    Miura, S.3    Ishida, A.4    Tanaka, H.5    Tanaka, J.6    Gejyo, F.7    Yoshizawa, H.8
  • 14
    • 0025793427 scopus 로고
    • Activation by anti-CD3 of tumor-draining lymph node cells for specific adoptive immunotherapy
    • Yoshizawa, H., K. Sakai, A. E. Chang, and S. Y. Shu. 1991. Activation by anti-CD3 of tumor-draining lymph node cells for specific adoptive immunotherapy. Cell. Immunol. 134: 473-479.
    • (1991) Cell. Immunol. , vol.134 , pp. 473-479
    • Yoshizawa, H.1    Sakai, K.2    Chang, A.E.3    Shu, S.Y.4
  • 15
    • 51549091043 scopus 로고    scopus 로고
    • Tumor-induced CD11b+Gr-1+ myeloid cells suppress T cell sensitization in tumor-draining lymph nodes
    • Watanabe, S., K. Deguchi, R. Zheng, H. Tamai, L. X. Wang, P. A. Cohen, and S. Shu. 2008. Tumor-induced CD11b+Gr-1+ myeloid cells suppress T cell sensitization in tumor-draining lymph nodes. J. Immunol. 181: 3291-3300.
    • (2008) J. Immunol. , vol.181 , pp. 3291-3300
    • Watanabe, S.1    Deguchi, K.2    Zheng, R.3    Tamai, H.4    Wang, L.X.5    Cohen, P.A.6    Shu, S.7
  • 19
    • 36048929066 scopus 로고    scopus 로고
    • Significance of regional draining lymph nodes in the development of tumor immunity: Implications for cancer immunotherapy
    • Zheng, R., J. Kjaergaard, W. T. Lee, P. A. Cohen, and S. Shu. 2007. Significance of regional draining lymph nodes in the development of tumor immunity: implications for cancer immunotherapy. Cancer Treat. Res. 135: 223-237.
    • (2007) Cancer Treat. Res. , vol.135 , pp. 223-237
    • Zheng, R.1    Kjaergaard, J.2    Lee, W.T.3    Cohen, P.A.4    Shu, S.5
  • 20
    • 0032034214 scopus 로고    scopus 로고
    • Purification of L-selectin(low) cells promotes the generation of highly potent CD4 antitumor effector T lymphocytes
    • Kagamu, H., and S. Shu. 1998. Purification of L-selectin(low) cells promotes the generation of highly potent CD4 antitumor effector T lymphocytes. J. Immunol. 160: 3444-3452.
    • (1998) J. Immunol. , vol.160 , pp. 3444-3452
    • Kagamu, H.1    Shu, S.2
  • 21
    • 0026574052 scopus 로고
    • Cellular interactions in effector cell generation and tumor regression mediated by anti-CD3/interleukin 2-activated tumor-draining lymph node cells
    • Yoshizawa, H., A. E. Chang, and S. Y. Shu. 1992. Cellular interactions in effector cell generation and tumor regression mediated by anti-CD3/interleukin 2-activated tumor-draining lymph node cells. Cancer Res. 52: 1129-1136.
    • (1992) Cancer Res. , vol.52 , pp. 1129-1136
    • Yoshizawa, H.1    Chang, A.E.2    Shu, S.Y.3
  • 22
    • 33745258657 scopus 로고    scopus 로고
    • Tumor-driven evolution of im-munosuppressive networks during malignant progression
    • Kim, R., M. Emi, K. Tanabe, and K. Arihiro. 2006. Tumor-driven evolution of im-munosuppressive networks during malignant progression. Cancer Res. 66: 5527-5536.
    • (2006) Cancer Res. , vol.66 , pp. 5527-5536
    • Kim, R.1    Emi, M.2    Tanabe, K.3    Arihiro, K.4
  • 23
    • 33947259319 scopus 로고    scopus 로고
    • Immunosup-pressive strategies that are mediated by tumor cells
    • Rabinovich, G. A., D. Gabrilovich, and E. M. Sotomayor. 2007. Immunosup-pressive strategies that are mediated by tumor cells. Annu. Rev. Immunol. 25: 267-296.
    • (2007) Annu. Rev. Immunol. , vol.25 , pp. 267-296
    • Rabinovich, G.A.1    Gabrilovich, D.2    Sotomayor, E.M.3
  • 24
    • 4544309074 scopus 로고    scopus 로고
    • TCR zeta-chain downregulation: Curtailing an excessive inflammatory immune response
    • Baniyash, M. 2004. TCR zeta-chain downregulation: curtailing an excessive inflammatory immune response. Nat. Rev. Immunol. 4: 675-687.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 675-687
    • Baniyash, M.1
  • 25
    • 36549014534 scopus 로고    scopus 로고
    • T cell immune reconsti-tution following lymphodepletion
    • Williams, K. M., F. T. Hakim, and R. E. Gress. 2007. T cell immune reconsti-tution following lymphodepletion. Semin. Immunol. 19: 318-330.
    • (2007) Semin. Immunol. , vol.19 , pp. 318-330
    • Williams, K.M.1    Hakim, F.T.2    Gress, R.E.3
  • 27
    • 84874108466 scopus 로고    scopus 로고
    • Chemoimmunotherapy: Reengineering tumor immunity
    • Chen, G., and L. A. Emens. 2013. Chemoimmunotherapy: reengineering tumor immunity. Cancer Immunol. Immunother. 62: 203-216.
    • (2013) Cancer Immunol. Immunother. , vol.62 , pp. 203-216
    • Chen, G.1    Emens, L.A.2
  • 29
    • 12744253307 scopus 로고    scopus 로고
    • Sinks, suppressors and antigen presenters: How lymphodepletion enhances T cell-mediated tumor immunotherapy
    • Klebanoff, C. A., H. T. Khong, P. A. Antony, D. C. Palmer, and N. P. Restifo. 2005. Sinks, suppressors and antigen presenters: how lymphodepletion enhances T cell-mediated tumor immunotherapy. Trends Immunol. 26: 111-117.
    • (2005) Trends Immunol. , vol.26 , pp. 111-117
    • Klebanoff, C.A.1    Khong, H.T.2    Antony, P.A.3    Palmer, D.C.4    Restifo, N.P.5
  • 30
    • 65249126905 scopus 로고    scopus 로고
    • Adoptive immunotherapy of cancer using CD4(+) T cells
    • Muranski, P., and N. P. Restifo. 2009. Adoptive immunotherapy of cancer using CD4(+) T cells. Curr. Opin. Immunol. 21: 200-208.
    • (2009) Curr. Opin. Immunol. , vol.21 , pp. 200-208
    • Muranski, P.1    Restifo, N.P.2
  • 32
    • 80051870268 scopus 로고    scopus 로고
    • Tumor-reactive CD4+ T cells: Plasticity beyond helper and regulatory activities
    • Quezada, S. A., and K. S. Peggs. 2011. Tumor-reactive CD4+ T cells: plasticity beyond helper and regulatory activities. Immunotherapy 3: 915-917.
    • (2011) Immunotherapy , vol.3 , pp. 915-917
    • Quezada, S.A.1    Peggs, K.S.2
  • 34
    • 0031782910 scopus 로고    scopus 로고
    • The role of CD4+ T cell responses in antitumor immunity
    • Pardoll, D. M., and S. L. Topalian. 1998. The role of CD4+ T cell responses in antitumor immunity. Curr. Opin. Immunol. 10: 588-594.
    • (1998) Curr. Opin. Immunol. , vol.10 , pp. 588-594
    • Pardoll, D.M.1    Topalian, S.L.2
  • 42
    • 84874116665 scopus 로고    scopus 로고
    • Metronomic chemotherapy with low-dose cyclophosphamide plus gemcitabine can induce anti-tumor T cell immunity in vivo
    • Tongu, M., N. Harashima, H. Monma, T. Inao, T. Yamada, H. Kawauchi, and M. Harada. 2013. Metronomic chemotherapy with low-dose cyclophosphamide plus gemcitabine can induce anti-tumor T cell immunity in vivo. Cancer Immunol. Immunother. 62: 383-391.
    • (2013) Cancer Immunol. Immunother. , vol.62 , pp. 383-391
    • Tongu, M.1    Harashima, N.2    Monma, H.3    Inao, T.4    Yamada, T.5    Kawauchi, H.6    Harada, M.7
  • 43
    • 0019226314 scopus 로고
    • Induction of experimental allergic encephalomyelitis in genetically resistant strains of mice
    • Lando, Z., D. Teitelbaum, and R. Arnon. 1980. Induction of experimental allergic encephalomyelitis in genetically resistant strains of mice. Nature 287: 551-552.
    • (1980) Nature , vol.287 , pp. 551-552
    • Lando, Z.1    Teitelbaum, D.2    Arnon, R.3
  • 44
    • 23044445625 scopus 로고    scopus 로고
    • Cyclophosphamide decreases the number, percentage and the function of CD25+ CD4+ regulatory T cells, which suppress induction of contact hypersensitivity
    • Ikezawa, Y., M. Nakazawa, C. Tamura, K. Takahashi, M. Minami, and Z. Ikezawa. 2005. Cyclophosphamide decreases the number, percentage and the function of CD25+ CD4+ regulatory T cells, which suppress induction of contact hypersensitivity. J. Dermatol. Sci. 39: 105-112.
    • (2005) J. Dermatol. Sci. , vol.39 , pp. 105-112
    • Ikezawa, Y.1    Nakazawa, M.2    Tamura, C.3    Takahashi, K.4    Minami, M.5    Ikezawa, Z.6
  • 45
    • 33750833099 scopus 로고    scopus 로고
    • Cyclophosphamide-induced type-1 diabetes in the NOD mouse is associated with a reduction of CD4+CD25+Foxp3+ regulatory T cells
    • Brode, S., T. Raine, P. Zaccone, and A. Cooke. 2006. Cyclophosphamide-induced type-1 diabetes in the NOD mouse is associated with a reduction of CD4+CD25+Foxp3+ regulatory T cells. J. Immunol. 177: 6603-6612.
    • (2006) J. Immunol. , vol.177 , pp. 6603-6612
    • Brode, S.1    Raine, T.2    Zaccone, P.3    Cooke, A.4
  • 46
    • 33644749039 scopus 로고    scopus 로고
    • Cyclophos-phamide augments inflammation by reducing immunosuppression in a mouse model of allergic airway disease
    • Su, Y. C., M. S. Rolph, M. A. Cooley, and W. A. Sewell. 2006. Cyclophos-phamide augments inflammation by reducing immunosuppression in a mouse model of allergic airway disease. J. Allergy Clin. Immunol. 117: 635-641.
    • (2006) J. Allergy Clin. Immunol. , vol.117 , pp. 635-641
    • Su, Y.C.1    Rolph, M.S.2    Cooley, M.A.3    Sewell, W.A.4
  • 47
    • 41949141343 scopus 로고    scopus 로고
    • Immune-potentiating effects of the chemother-apeutic drug cyclophosphamide
    • Brode, S., and A. Cooke. 2008. Immune-potentiating effects of the chemother-apeutic drug cyclophosphamide. Crit. Rev. Immunol. 28: 109-126.
    • (2008) Crit. Rev. Immunol. , vol.28 , pp. 109-126
    • Brode, S.1    Cooke, A.2
  • 48
    • 77957729952 scopus 로고    scopus 로고
    • An immunohistochemical study on the distribution and frequency of T regulatory cells in pancreatic islets of NOD mice during various stages of spontaneous and cyclophosphamide-accelerated diabetes
    • Kaur, S., W. L. Tan, C. Soo, C. C. Cheung, J. Stewart, and S. Reddy. 2010. An immunohistochemical study on the distribution and frequency of T regulatory cells in pancreatic islets of NOD mice during various stages of spontaneous and cyclophosphamide-accelerated diabetes. Pancreas 39: 1024-1033.
    • (2010) Pancreas , vol.39 , pp. 1024-1033
    • Kaur, S.1    Tan, W.L.2    Soo, C.3    Cheung, C.C.4    Stewart, J.5    Reddy, S.6
  • 52
    • 84863924314 scopus 로고    scopus 로고
    • Regulatory T-cell modulation using cyclo-phosphamide in vaccine approaches: A current perspective
    • Le, D. T., and E. M. Jaffee. 2012. Regulatory T-cell modulation using cyclo-phosphamide in vaccine approaches: A current perspective. Cancer Res. 72: 3439-3444.
    • (2012) Cancer Res. , vol.72 , pp. 3439-3444
    • Le, D.T.1    Jaffee, E.M.2
  • 53
    • 77953730756 scopus 로고    scopus 로고
    • Selective depletion of CD4+CD25+Foxp3+ regulatory T cells by low-dose cyclophos-phamide is explained by reduced intracellular ATP levels
    • Zhao, J., Y. Cao, Z. Lei, Z. Yang, B. Zhang, and B. Huang. 2010. Selective depletion of CD4+CD25+Foxp3+ regulatory T cells by low-dose cyclophos-phamide is explained by reduced intracellular ATP levels. Cancer Res. 70: 4850-4858.
    • (2010) Cancer Res. , vol.70 , pp. 4850-4858
    • Zhao, J.1    Cao, Y.2    Lei, Z.3    Yang, Z.4    Zhang, B.5    Huang, B.6
  • 54
    • 0347626100 scopus 로고    scopus 로고
    • Synergistic effect of metronomic dosing of cyclophosphamide combined with specific antitumor immunotherapy in a murine melanoma model
    • Hermans, I. F., T. W. Chong, M. J. Palmowski, A. L. Harris, and V. Cerundolo. 2003. Synergistic effect of metronomic dosing of cyclophosphamide combined with specific antitumor immunotherapy in a murine melanoma model. Cancer Res. 63: 8408-8413.
    • (2003) Cancer Res. , vol.63 , pp. 8408-8413
    • Hermans, I.F.1    Chong, T.W.2    Palmowski, M.J.3    Harris, A.L.4    Cerundolo, V.5
  • 57
    • 84860333968 scopus 로고    scopus 로고
    • CD20-specific adoptive immunotherapy for lymphoma using a chimeric antigen receptor with both CD28 and 4-1BB domains: Pilot clinical trial results
    • Till, B. G., M. C. Jensen, J. Wang, X. Qian, A. K. Gopal, D. G. Maloney, C. G. Lindgren, Y. Lin, J. M. Pagel, L. E. Budde, et al. 2012. CD20-specific adoptive immunotherapy for lymphoma using a chimeric antigen receptor with both CD28 and 4-1BB domains: pilot clinical trial results. Blood 119: 3940-3950.
    • (2012) Blood , vol.119 , pp. 3940-3950
    • Till, B.G.1    Jensen, M.C.2    Wang, J.3    Qian, X.4    Gopal, A.K.5    Maloney, D.G.6    Lindgren, C.G.7    Lin, Y.8    Pagel, J.M.9    Budde, L.E.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.