Identification of the docking site for CD3 on the T cell receptor β chain by solution NMR

Journal of Biological Chemistry

Volumn 290, Issue 32, 2015, Pages 19796-19805

  He, Yanan ^a,b   Rangarajan, Sneha ^a,b   Kerzic, Melissa ^a   Luo, Ming ^a,c   Chen, Yihong ^a   Wang, Qian ^a   Yin, Yiyuan ^a   Workman, Creg J ^d   Vignali, Kate M ^d   Vignali, Dario A A ^d   Mariuzza, Roy A ^a,b   Orban, John ^a,b  

^a UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^b University of Maryland   (United States)

^c UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; CELL SIGNALING; CELLS; CHAINS; CYTOLOGY; DIMERS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PEPTIDES;

CELL-BASED ASSAYS; EXTRACELLULAR DOMAINS; GLYCOSYLATION SITES; SPATIAL ORGANIZATION; SPECIFIC INTERACTION; T CELL RECEPTOR; T-CELL RECEPTORS; WEAK INTERACTIONS;

T-CELLS;

CD3 ANTIGEN; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR BETA CHAIN; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN SUBUNIT; RECOMBINANT PROTEIN;

ALPHA HELIX; ARTICLE; BINDING AFFINITY; CELL ASSAY; COMPLEX FORMATION; CONTROLLED STUDY; HUMAN; HYDROPHILICITY; LYMPHOCYTE MEMBRANE; MOLECULAR DOCKING; MOLECULAR INTERACTION; MOLECULAR RECOGNITION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN GLYCOSYLATION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; T LYMPHOCYTE; AMINO ACID SEQUENCE; CHEMISTRY; ESCHERICHIA COLI; GENE EXPRESSION; GENETICS; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; MUTATION; PROTEIN FOLDING; PROTEIN MULTIMERIZATION; PROTEIN SECONDARY STRUCTURE; PROTEIN SUBUNIT; PROTEIN TERTIARY STRUCTURE;

AMINO ACID SEQUENCE; ANTIGENS, CD3; ESCHERICHIA COLI; GENE EXPRESSION; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR DOCKING SIMULATION; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN FOLDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; RECEPTOR-CD3 COMPLEX, ANTIGEN, T-CELL; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECOMBINANT PROTEINS; T-LYMPHOCYTES;

EID: 84936786874     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.663799     Document Type: Article

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