Elimination of BMP7 from the developing limb mesenchyme leads to articular cartilage degeneration and synovial inflammation with increased age

FEBS Letters

Volumn 589, Issue 11, 2015, Pages 1240-1248

  Abula, Kahaer ^a   Muneta, Takeshi ^a   Miyatake, Kazumasa ^a   Yamada, Jun ^a   Matsukura, Yu ^a   Inoue, Makiko ^a   Sekiya, Ichiro ^a   Graf, Daniel ^b   Economides, Aris N ^c   Rosen, Vicki ^d   Tsuji, Kunikazu ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b UNIVERSITY OF ALBERTA   (Canada)

^c REGENERON PHARMACEUTICALS INC   (United States)

^d HARVARD SCHOOL OF DENTAL MEDICINE   (United States)

Author keywords

Activin A; Articular cartilage; Bone morphogenetic protein 7; Osteoarthritis; Proteoglycan; Synovitis

Indexed keywords

ACTIVIN; ACTIVIN A; AGGRECAN; BMP7 PROTEIN, HUMAN; BMP7 PROTEIN, MOUSE; OSTEOGENIC PROTEIN 1;

ADULT; ANIMAL; ARTICULAR CARTILAGE; BIOSYNTHESIS; EMBRYOLOGY; GENE EXPRESSION REGULATION; GENETICS; HINDLIMB; HUMAN; KNOCKOUT MOUSE; MESODERM; METABOLISM; MOUSE; OSTEOARTHRITIS; PATHOLOGY; SYNOVITIS;

ACTIVINS; ADULT; AGGRECANS; ANIMALS; BONE MORPHOGENETIC PROTEIN 7; CARTILAGE, ARTICULAR; GENE EXPRESSION REGULATION; HINDLIMB; HUMANS; MESODERM; MICE; MICE, KNOCKOUT; OSTEOARTHRITIS; SYNOVITIS;

EID: 84936774529     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2015.04.004     Document Type: Article

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