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Volumn 74, Issue 5, 2014, Pages 1541-1553

MicroRNA-148a is a prognostic oncomiR that targets MIG6 and BIM to regulate EGFR and apoptosis in glioblastoma

Author keywords

[No Author keywords available]

Indexed keywords

BIM PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; MICRORNA; MICRORNA 148A; MITOGEN INDUCIBLE GENE 6 PROTEIN; RAB7 PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

EID: 84896500851     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-13-1449     Document Type: Article
Times cited : (109)

References (49)
  • 2
    • 58149471244 scopus 로고    scopus 로고
    • Epidemiology of brain tumors
    • Ohgaki H. Epidemiology of brain tumors. Methods Mol Biol 2009; 472:323-42.
    • (2009) Methods Mol Biol , vol.472 , pp. 323-342
    • Ohgaki, H.1
  • 3
    • 48249125791 scopus 로고    scopus 로고
    • Malignant gliomas in adults
    • Wen PY, Kesari S. Malignant gliomas in adults. N Engl J Med 2008; 359:492-507.
    • (2008) N Engl J Med , vol.359 , pp. 492-507
    • Wen, P.Y.1    Kesari, S.2
  • 6
    • 77956868654 scopus 로고    scopus 로고
    • Epidermal growth factor receptor in glioma: Signal transduction, neuropathology, imaging, and radioresistance
    • Hatanpaa KJ, Burma S, Zhao D, Habib AA. Epidermal growth factor receptor in glioma: signal transduction, neuropathology, imaging, and radioresistance. Neoplasia 2010;12:675-84.
    • (2010) Neoplasia , vol.12 , pp. 675-684
    • Hatanpaa, K.J.1    Burma, S.2    Zhao, D.3    Habib, A.A.4
  • 8
    • 27744439793 scopus 로고    scopus 로고
    • Glioblastoma multiforme and the epidermal growth factor receptor
    • Friedman HS, Bigner DD. Glioblastoma multiforme and the epidermal growth factor receptor. N Engl J Med 2005;353:1997-9.
    • (2005) N Engl J Med , vol.353 , pp. 1997-1999
    • Friedman, H.S.1    Bigner, D.D.2
  • 10
    • 62649175431 scopus 로고    scopus 로고
    • Mechanisms of erbb receptor negative regulation and relevance in cancer
    • Fry WH, Kotelawala L, Sweeney C, Carraway KL III. Mechanisms of ErbB receptor negative regulation and relevance in cancer. Exp Cell Res 2009;315:697-706.
    • (2009) Exp Cell Res , vol.315 , pp. 697-706
    • Fry, W.H.1    Kotelawala, L.2    Sweeney, C.3    Carraway III, K.L.4
  • 12
    • 36749011864 scopus 로고    scopus 로고
    • Inhibition of the egf receptor by binding of mig6 to an activating kinase domain interface
    • Zhang X, Pickin KA, Bose R, Jura N, Cole PA, Kuriyan J. Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface. Nature 2007;450:741-4.
    • (2007) Nature , vol.450 , pp. 741-744
    • Zhang, X.1    Pickin, K.A.2    Bose, R.3    Jura, N.4    Cole, P.A.5    Kuriyan, J.6
  • 13
    • 0033796072 scopus 로고    scopus 로고
    • Inhibition of erbb-2 mitogenic and transforming activity by ralt, a mitogen-induced signal transducer which binds to the erbb-2 kinase domain
    • Fiorentino L, Pertica C, Fiorini M, Talora C, Crescenzi M, Castellani L, et al. Inhibition of ErbB-2 mitogenic and transforming activity by RALT, a mitogen-induced signal transducer which binds to the ErbB-2 kinase domain. Mol Cell Biol 2000;20:7735-50.
    • (2000) Mol Cell Biol , vol.20 , pp. 7735-7750
    • Fiorentino, L.1    Pertica, C.2    Fiorini, M.3    Talora, C.4    Crescenzi, M.5    Castellani, L.6
  • 14
    • 78649823233 scopus 로고    scopus 로고
    • Integrated genomic analyses identify errfi1 and tacc3 as glioblastoma-Targeted genes
    • Duncan CG, Killela PJ, Payne CA, Lampson B, Chen WC, Liu J, et al. Integrated genomic analyses identify ERRFI1 and TACC3 as glioblastoma-Targeted genes. Oncotarget 2010;1:265-77.
    • (2010) Oncotarget , vol.1 , pp. 265-277
    • Duncan, C.G.1    Killela, P.J.2    Payne, C.A.3    Lampson, B.4    Chen, W.C.5    Liu, J.6
  • 15
    • 0842281645 scopus 로고    scopus 로고
    • Cell death: Critical control points
    • Danial NN, Korsmeyer SJ. Cell death: critical control points. Cell 2004;116:205-19.
    • (2004) Cell , vol.116 , pp. 205-219
    • Danial, N.N.1    Korsmeyer, S.J.2
  • 16
    • 0037428798 scopus 로고    scopus 로고
    • Temozolomide induces apoptosis and senescence in glioma cells cultured as multicellular spheroids
    • Gunther W, Pawlak E, Damasceno R, Arnold H, Terzis AJ. Temozolomide induces apoptosis and senescence in glioma cells cultured as multicellular spheroids. Br J Cancer 2003;88:463-9.
    • (2003) Br J Cancer , vol.88 , pp. 463-469
    • Gunther, W.1    Pawlak, E.2    Damasceno, R.3    Arnold, H.4    Terzis, A.J.5
  • 17
    • 33745935557 scopus 로고    scopus 로고
    • Regulated targeting of bax and bak to intracellular membranes during apoptosis
    • Heath-Engel HM, Shore GC. Regulated targeting of Bax and Bak to intracellular membranes during apoptosis. Cell Death Differ 2006;13:1277-80.
    • (2006) Cell Death Differ , vol.13 , pp. 1277-1280
    • Heath-Engel, H.M.1    Shore, G.C.2
  • 18
    • 35648949422 scopus 로고    scopus 로고
    • Bim mediates egfr tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic egfr mutations
    • Costa DB, Halmos B, Kumar A, Schumer ST, Huberman MS, Boggon TJ, et al. BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations. PLoS Med 2007;4:1669-79.
    • (2007) PLoS Med , vol.4 , pp. 1669-1679
    • Costa, D.B.1    Halmos, B.2    Kumar, A.3    Schumer, S.T.4    Huberman, M.S.5    Boggon, T.J.6
  • 19
    • 37549001026 scopus 로고    scopus 로고
    • Proapoptotic bh3-only bcl-2 family protein bim connects death signaling from epidermal growth factor receptor inhibition to the mitochondrion
    • Deng J, Shimamura T, Perera S, Carlson NE, Cai D, Shapiro GI, et al. Proapoptotic BH3-only BCL-2 family protein BIM connects death signaling from epidermal growth factor receptor inhibition to the mitochondrion. Cancer Res 2007;67:11867-75.
    • (2007) Cancer Res , vol.67 , pp. 11867-11875
    • Deng, J.1    Shimamura, T.2    Perera, S.3    Carlson, N.E.4    Cai, D.5    Shapiro, G.I.6
  • 20
  • 21
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are micro-rna targets
    • Lewis BP, Burge CB, Bartel DP. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are micro-RNA targets. Cell 2005;120:15-20.
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 22
    • 12144290519 scopus 로고    scopus 로고
    • Human micrornagenes are frequently located at fragile sites and genomic regions involved in cancers
    • Calin GA, Sevignani C, Dumitru CD, Hyslop T, Noch E, Yendamuri S, et al.Human microRNAgenes are frequently located at fragile sites and genomic regions involved in cancers. Proc Natl Acad Sci U S A 2004; 101:2999-3004.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 2999-3004
    • Calin, G.A.1    Sevignani, C.2    Dumitru, C.D.3    Hyslop, T.4    Noch, E.5    Yendamuri, S.6
  • 23
    • 84860344943 scopus 로고    scopus 로고
    • The role of micrornas in glioma initiation and progression
    • Zhang Y, Dutta A, Abounader R. The role of microRNAs in glioma initiation and progression. Front Biosci 2012;17:700-12.
    • (2012) Front Biosci , vol.17 , pp. 700-712
    • Zhang, Y.1    Dutta, A.2    Abounader, R.3
  • 24
    • 70350221952 scopus 로고    scopus 로고
    • Microrna-34a inhibits glioblastoma growth by targeting multiple oncogenes
    • Li Y, Guessous F, Zhang Y, Dipierro C, Kefas B, Johnson E, et al. MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes. Cancer Res 2009;69:7569-76.
    • (2009) Cancer Res , vol.69 , pp. 7569-7576
    • Li, Y.1    Guessous, F.2    Zhang, Y.3    Dipierro, C.4    Kefas, B.5    Johnson, E.6
  • 26
    • 84872544617 scopus 로고    scopus 로고
    • Targeting of tgfbeta signature and its essential component ctgf by mir-18 correlates with improved survival in glioblastoma
    • Fox JL, Dews M, Minn AJ, Thomas-Tikhonenko A. Targeting of TGFbeta signature and its essential component CTGF by miR-18 correlates with improved survival in glioblastoma. RNA 2013;19: 177-90.
    • (2013) RNA , vol.19 , pp. 177-190
    • Fox, J.L.1    Dews, M.2    Minn, A.J.3    Thomas-Tikhonenko, A.4
  • 27
    • 72849108572 scopus 로고    scopus 로고
    • The neuronal microrna mir-326 acts in a feedback loop with notch and has therapeutic potential against brain tumors
    • Kefas B, Comeau L, Floyd DH, Seleverstov O, Godlewski J, Schmittgen T, et al. The neuronal microRNA miR-326 acts in a feedback loop with notch and has therapeutic potential against brain tumors. J Neurosci 2009;29:15161-8.
    • (2009) J Neurosci , vol.29 , pp. 15161-15168
    • Kefas, B.1    Comeau, L.2    Floyd, D.H.3    Seleverstov, O.4    Godlewski, J.5    Schmittgen, T.6
  • 30
    • 77649259296 scopus 로고    scopus 로고
    • Microrna-451 regulates lkb1/ampk signaling and allows adaptation to metabolic stress in glioma cells
    • Godlewski J, Nowicki MO, Bronisz A, Nuovo G, Palatini J, De Lay M, et al. MicroRNA-451 regulates LKB1/AMPK signaling and allows adaptation to metabolic stress in glioma cells. Mol Cell 2010;37: 620-32.
    • (2010) Mol Cell , vol.37 , pp. 620-632
    • Godlewski, J.1    Nowicki, M.O.2    Bronisz, A.3    Nuovo, G.4    Palatini, J.5    De Lay, M.6
  • 32
    • 33646358694 scopus 로고    scopus 로고
    • Tumor stem cells derived from glioblastomas cultured in bfgf and egf more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
    • Lee J, Kotliarova S, Kotliarov Y, Li A, Su Q, Donin NM, et al. Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines. Cancer Cell 2006;9:391-403.
    • (2006) Cancer Cell , vol.9 , pp. 391-403
    • Lee, J.1    Kotliarova, S.2    Kotliarov, Y.3    Li, A.4    Su, Q.5    Donin, N.M.6
  • 33
    • 84896512162 scopus 로고    scopus 로고
    • R-project.org [Internet]. Vienna, Austria: Institute for Statistics and Mathematics of WU (Wirtschaftsuniversiẗat Wien). [updated 2013 Sep 25; cited 2013 May 14] Available from
    • R-project.org [Internet]. Vienna, Austria: Institute for Statistics and Mathematics of WU (Wirtschaftsuniversiẗat Wien). [updated 2013 Sep 25; cited 2013 May 14]. Available from: http://www.r-project.org/.
  • 34
    • 33644872577 scopus 로고    scopus 로고
    • Limma: Linear models for microarray data
    • In:Gentleman R, Carey V, Huber W, Irizarry R, Dudoit S, editors, New York Springer
    • Smyth G. Limma: Linear models for microarray data. In:Gentleman R, Carey V, Huber W, Irizarry R, Dudoit S, editors. Bioinformatics and Computational Biology Solutions using R and Bioconductor. New York: Springer; 2005. p. 397-420.
    • (2005) Bioinformatics and Computational Biology Solutions using R and Bioconductor , pp. 397-420
    • Smyth, G.1
  • 35
    • 27144524893 scopus 로고    scopus 로고
    • The scatter factor/hepatocyte growth factor: C-met pathway in human embryonal central nervous system tumor malignancy
    • Li Y, Lal B, Kwon S, Fan X, Saldanha U, Reznik TE, et al. The scatter factor/hepatocyte growth factor: c-met pathway in human embryonal central nervous system tumor malignancy. Cancer Res 2005;65: 9355-62.
    • (2005) Cancer Res , vol.65 , pp. 9355-9362
    • Li, Y.1    Lal, B.2    Kwon, S.3    Fan, X.4    Saldanha, U.5    Reznik, T.E.6
  • 36
    • 38549146069 scopus 로고    scopus 로고
    • Functional and molecular interactions between the hgf/c-met pathway and c-myc in large-cell medulloblastoma
    • Li Y, Guessous F, Johnson EB, Eberhart CG, Li XN, Shu Q, et al. Functional and molecular interactions between the HGF/c-Met pathway and c-Myc in large-cell medulloblastoma. Lab Invest 2008;88: 98-111.
    • (2008) Lab Invest , vol.88 , pp. 98-111
    • Li, Y.1    Guessous, F.2    Johnson, E.B.3    Eberhart, C.G.4    Li, X.N.5    Shu, Q.6
  • 37
    • 35948976100 scopus 로고    scopus 로고
    • Protein kinase c-Alpha-mediated regulation of low-density lipoprotein receptor related protein and urokinase increases astrocytoma invasion
    • Amos S, Mut M, diPierro CG, Carpenter JE, Xiao A, Kohutek ZA, et al. Protein kinase C-Alpha-mediated regulation of low-density lipoprotein receptor related protein and urokinase increases astrocytoma invasion. Cancer Res 2007;67:10241-51.
    • (2007) Cancer Res , vol.67 , pp. 10241-10251
    • Amos, S.1    Mut, M.2    Di Pierro, C.G.3    Carpenter, J.E.4    Xiao, A.5    Kohutek, Z.A.6
  • 38
    • 84881067866 scopus 로고    scopus 로고
    • A novel pten/mutant p53/c-myc/bcl-xl axis mediates context-dependent oncogenic effects of pten with implications for cancer prognosis and therapy
    • Huang X, Zhang Y, Tang Y, Butler N, Kim J, Guessous F, et al. A novel PTEN/mutant p53/c-Myc/Bcl-XL axis mediates context-dependent oncogenic effects of PTEN with implications for cancer prognosis and therapy. Neoplasia 2013;15:952-65.
    • (2013) Neoplasia , vol.15 , pp. 952-965
    • Huang, X.1    Zhang, Y.2    Tang, Y.3    Butler, N.4    Kim, J.5    Guessous, F.6
  • 41
    • 84867985496 scopus 로고    scopus 로고
    • Microrna-148a is silenced by hypermethylation and interacts with dna methyltransferase 1 in gastric cancer
    • Zhu A, Xia J, Zuo J, Jin S, Zhou H, Yao L, et al. MicroRNA-148a is silenced by hypermethylation and interacts with DNA methyltransferase 1 in gastric cancer. Med Oncol 2012;29:2701-9.
    • (2012) Med Oncol , vol.29 , pp. 2701-2709
    • Zhu, A.1    Xia, J.2    Zuo, J.3    Jin, S.4    Zhou, H.5    Yao, L.6
  • 42
    • 84055222088 scopus 로고    scopus 로고
    • Microrna-148a suppresses tumor cell invasion and metastasis by downregulating rock1 in gastric cancer
    • Zheng B, Liang L, Wang C, Huang S, Cao X, Zha R, et al. MicroRNA-148a suppresses tumor cell invasion and metastasis by downregulating ROCK1 in gastric cancer. Clin Cancer Res 2011;17:7574-83.
    • (2011) Clin Cancer Res , vol.17 , pp. 7574-7583
    • Zheng, B.1    Liang, L.2    Wang, C.3    Huang, S.4    Cao, X.5    Zha, R.6
  • 43
    • 80053360154 scopus 로고    scopus 로고
    • Microrna-148a is down-regulated in human pancreatic ductal adenocarcinomas and regulates cell survival by targeting cdc25b
    • Liffers ST, Munding JB, Vogt M, Kuhlmann JD, Verdoodt B, Nambiar S, et al. MicroRNA-148a is down-regulated in human pancreatic ductal adenocarcinomas and regulates cell survival by targeting CDC25B. Lab Invest 2011;91:1472-9.
    • (2011) Lab Invest , vol.91 , pp. 1472-1479
    • Liffers, S.T.1    Munding, J.B.2    Vogt, M.3    Kuhlmann, J.D.4    Verdoodt, B.5    Nambiar, S.6
  • 45
    • 84857002194 scopus 로고    scopus 로고
    • Bim expression in treatment-naive cancers predicts responsiveness to kinase inhibitors
    • Faber AC, Corcoran RB, Ebi H, Sequist LV, Waltman BA, Chung E, et al. BIM expression in treatment-naive cancers predicts responsiveness to kinase inhibitors. Cancer Discov 2011;1:352-65.
    • (2011) Cancer Discov , vol.1 , pp. 352-365
    • Faber, A.C.1    Corcoran, R.B.2    Ebi, H.3    Sequist, L.V.4    Waltman, B.A.5    Chung, E.6
  • 46
    • 84873208217 scopus 로고    scopus 로고
    • The rescue of mir-148a expression in pancreatic cancer: An inappropriate therapeutic tool
    • Delpu Y, Lulka H, Sicard F, Saint-Laurent N, Lopez F, Hanoun N, et al. The rescue of miR-148a expression in pancreatic cancer: an inappropriate therapeutic tool. PLoS ONE 2013;8:e55513.
    • (2013) PLoS ONE , vol.8
    • Delpu, Y.1    Lulka, H.2    Sicard, F.3    Saint-Laurent, N.4    Lopez, F.5    Hanoun, N.6
  • 47
    • 80053987030 scopus 로고    scopus 로고
    • Mir-148a promotes apoptosis by targeting bcl-2 in colorectal cancer
    • Zhang H, Li Y, Huang Q, Ren X, Hu H, Sheng H, et al. MiR-148a promotes apoptosis by targeting Bcl-2 in colorectal cancer. Cell Death Differ 2011;18:1702-10.
    • (2011) Cell Death Differ , vol.18 , pp. 1702-1710
    • Zhang, H.1    Li, Y.2    Huang, Q.3    Ren, X.4    Hu, H.5    Sheng, H.6
  • 48
    • 84905388786 scopus 로고    scopus 로고
    • MicroRNA-148a suppresses the epithelial-mesenchymal transition and metastasis of hepatoma cells by targeting Met/Snail signaling
    • Sep 9. [Epub ahead of print].
    • Zhang JP, Zeng C, Xu L, Gong J, Fang JH, Zhuang SM. MicroRNA-148a suppresses the epithelial-mesenchymal transition and metastasis of hepatoma cells by targeting Met/Snail signaling. Oncogene 2013 Sep 9. [Epub ahead of print].
    • (2013) Oncogene
    • Zhang, J.P.1    Zeng, C.2    Xu, L.3    Gong, J.4    Fang, J.H.5    Zhuang, S.M.6
  • 49
    • 79953309923 scopus 로고    scopus 로고
    • A ten-microRNA expression signature predicts survival in glioblastoma
    • Srinivasan S, Patric IR, Somasundaram K. A ten-microRNA expression signature predicts survival in glioblastoma. PLoS ONE 2011;6:e17438.
    • (2011) PLoS ONE , vol.6
    • Srinivasan, S.1    Patric, I.R.2    Somasundaram, K.3


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