-
1
-
-
70849099495
-
The extracellular matrix: not just pretty fibrils
-
Hynes, R.O. (2009) The extracellular matrix: not just pretty fibrils. Science, 326, 1216-1219.
-
(2009)
Science
, vol.326
, pp. 1216-1219
-
-
Hynes, R.O.1
-
2
-
-
84855525455
-
LTBPs, more than just an escort service
-
Todorovic, V. and Rifkin, D.B. (2012) LTBPs, more than just an escort service. J. Cell. Biochem., 113, 410-418.
-
(2012)
J. Cell. Biochem
, vol.113
, pp. 410-418
-
-
Todorovic, V.1
Rifkin, D.B.2
-
3
-
-
0036713792
-
Disruption of the gene encoding the latent transforming growth factor-beta binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer
-
Sterner-Kock, A., Thorey, I.S., Koli, K., Wempe, F., Otte, J., Bangsow, T., Kuhlmeier, K., Kirchner, T., Jin, S., Keski-Oja, J. et al. (2002) Disruption of the gene encoding the latent transforming growth factor-beta binding protein 4 (LTBP-4) causes abnormal lung development, cardiomyopathy, and colorectal cancer. Genes Dev., 16, 2264-2273.
-
(2002)
Genes Dev
, vol.16
, pp. 2264-2273
-
-
Sterner-Kock, A.1
Thorey, I.S.2
Koli, K.3
Wempe, F.4
Otte, J.5
Bangsow, T.6
Kuhlmeier, K.7
Kirchner, T.8
Jin, S.9
Keski-Oja, J.10
-
4
-
-
71849092773
-
Mutations in LTBP4 cause a syndrome of impaired pulmonary, gastrointestinal, genitourinary, musculoskeletal, and dermal development
-
Urban, Z., Hucthagowder, V., Schurmann, N., Todorovic, V., Zilberberg, L., Choi, J., Sens, C., Brown, C.W., Clark, R.D., Holland, K.E. et al. (2009) Mutations in LTBP4 cause a syndrome of impaired pulmonary, gastrointestinal, genitourinary, musculoskeletal, and dermal development. Am. J. Hum. Genet., 85, 593-605.
-
(2009)
Am. J. Hum. Genet
, vol.85
, pp. 593-605
-
-
Urban, Z.1
Hucthagowder, V.2
Schurmann, N.3
Todorovic, V.4
Zilberberg, L.5
Choi, J.6
Sens, C.7
Brown, C.W.8
Clark, R.D.9
Holland, K.E.10
-
5
-
-
84871618476
-
Comprehensive clinical and molecular analysis of 12 families with type 1 recessive cutis laxa
-
Callewaert, B., Su, C.T., Van Damme, T., Vlummens, P., Malfait, F., Vanakker, O., Schulz, B., Mac Neal, M., Davis, E. C., Lee, J.G. et al. (2013) Comprehensive clinical and molecular analysis of 12 families with type 1 recessive cutis laxa. Hum. Mutat., 34, 111-121.
-
(2013)
Hum. Mutat
, vol.34
, pp. 111-121
-
-
Callewaert, B.1
Su, C.T.2
Van Damme, T.3
Vlummens, P.4
Malfait, F.5
Vanakker, O.6
Schulz, B.7
Mac Neal, M.8
Davis, E.C.9
Lee, J.G.10
-
6
-
-
60849117528
-
Dual functions for LTBP in lung development: LTBP-4 independently modulates elastogenesis and TGF-beta activity
-
Dabovic, B., Chen, Y., Choi, J., Vassallo, M., Dietz, H.C., Ramirez, F., von Melchner, H., Davis, E.C. and Rifkin, D.B. (2009) Dual functions for LTBP in lung development: LTBP-4 independently modulates elastogenesis and TGF-beta activity. J. Cell. Physiol., 219, 14-22.
-
(2009)
J. Cell. Physiol
, vol.219
, pp. 14-22
-
-
Dabovic, B.1
Chen, Y.2
Choi, J.3
Vassallo, M.4
Dietz, H.C.5
Ramirez, F.6
von Melchner, H.7
Davis, E.C.8
Rifkin, D.B.9
-
7
-
-
79954625123
-
Noncanonical TGFbeta signaling contributes to aortic aneurysm progression in Marfan syndrome mice
-
Holm, T.M., Habashi, J.P., Doyle, J.J., Bedja, D., Chen, Y., van Erp, C., Lindsay, M.E., Kim, D., Schoenhoff, F., Cohn, R.D. et al. (2011) Noncanonical TGFbeta signaling contributes to aortic aneurysm progression in Marfan syndrome mice. Science, 332, 358-361.
-
(2011)
Science
, vol.332
, pp. 358-361
-
-
Holm, T.M.1
Habashi, J.P.2
Doyle, J.J.3
Bedja, D.4
Chen, Y.5
van Erp, C.6
Lindsay, M.E.7
Kim, D.8
Schoenhoff, F.9
Cohn, R.D.10
-
8
-
-
0037373277
-
Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome
-
Neptune, E.R., Frischmeyer, P.A., Arking, D.E., Myers, L., Bunton, T.E., Gayraud, B., Ramirez, F., Sakai, L.Y. and Dietz, H.C. (2003) Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome. Nat. Genet., 33, 407-411.
-
(2003)
Nat. Genet
, vol.33
, pp. 407-411
-
-
Neptune, E.R.1
Frischmeyer, P.A.2
Arking, D.E.3
Myers, L.4
Bunton, T.E.5
Gayraud, B.6
Ramirez, F.7
Sakai, L.Y.8
Dietz, H.C.9
-
9
-
-
20144367207
-
A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2
-
Loeys, B.L., Chen, J., Neptune, E.R., Judge, D.P., Podowski, M., Holm, T., Meyers, J., Leitch, C.C., Katsanis, N., Sharifi, N. et al. (2005) A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2. Nat. Genet., 37, 275-281.
-
(2005)
Nat. Genet
, vol.37
, pp. 275-281
-
-
Loeys, B.L.1
Chen, J.2
Neptune, E.R.3
Judge, D.P.4
Podowski, M.5
Holm, T.6
Meyers, J.7
Leitch, C.C.8
Katsanis, N.9
Sharifi, N.10
-
10
-
-
77957752791
-
Mechanisms of emphysema in autosomal dominant cutis laxa
-
Hu, Q., Shifren, A., Choi, J., Szabo, Z., Starcher, B.C., Knutsen, R.H., Shipley, J.M., Davis, E.C., Mecham, R.P. and Urban, Z. (2010) Mechanisms of emphysema in autosomal dominant cutis laxa. Matrix Biol., 29, 621-628.
-
(2010)
Matrix Biol
, vol.29
, pp. 621-628
-
-
Hu, Q.1
Shifren, A.2
Choi, J.3
Szabo, Z.4
Starcher, B.C.5
Knutsen, R.H.6
Shipley, J.M.7
Davis, E.C.8
Mecham, R.P.9
Urban, Z.10
-
11
-
-
79952774030
-
New insights into the pathogenesis of autosomal-dominant cutis laxa with report of five ELN mutations
-
Callewaert, B., Renard, M., Hucthagowder, V., Albrecht, B., Hausser, I., Blair, E., Dias, C., Albino, A., Wachi, H., Sato, F. et al. (2011) New insights into the pathogenesis of autosomal-dominant cutis laxa with report of five ELN mutations. Hum. Mutat., 32, 445-455.
-
(2011)
Hum. Mutat
, vol.32
, pp. 445-455
-
-
Callewaert, B.1
Renard, M.2
Hucthagowder, V.3
Albrecht, B.4
Hausser, I.5
Blair, E.6
Dias, C.7
Albino, A.8
Wachi, H.9
Sato, F.10
-
12
-
-
45949092534
-
Angiotensin II blockade and aorticroot dilation in Marfan's syndrome
-
Brooke, B.S., Habashi, J.P., Judge, D.P., Patel, N., Loeys, B. and Dietz, H.C. 3rd. (2008) Angiotensin II blockade and aorticroot dilation in Marfan's syndrome. N. Engl. J. Med., 358, 2787-2795.
-
(2008)
N. Engl. J. Med
, vol.358
, pp. 2787-2795
-
-
Brooke, B.S.1
Habashi, J.P.2
Judge, D.P.3
Patel, N.4
Loeys, B.5
Dietz, H.C.6
-
13
-
-
70450187617
-
The regulation of TGFbeta signal transduction
-
Moustakas, A. and Heldin, C.H. (2009) The regulation of TGFbeta signal transduction. Development, 136, 3699-3714.
-
(2009)
Development
, vol.136
, pp. 3699-3714
-
-
Moustakas, A.1
Heldin, C.H.2
-
14
-
-
84864568158
-
Coated pit-mediated endocytosis of the type I transforming growth factor-beta (TGF-beta) receptor depends on a dileucine family signal and is not required for signaling
-
Shapira, K.E., Gross, A., Ehrlich, M. and Henis, Y.I. (2012) Coated pit-mediated endocytosis of the type I transforming growth factor-beta (TGF-beta) receptor depends on a dileucine family signal and is not required for signaling. J. Biol. Chem., 287, 26876-26889.
-
(2012)
J. Biol. Chem
, vol.287
, pp. 26876-26889
-
-
Shapira, K.E.1
Gross, A.2
Ehrlich, M.3
Henis, Y.I.4
-
15
-
-
0042030808
-
Lysosomal and proteasomal degradation play distinct roles in the life cycle of Cx43 in gap junctional intercellular communication-deficient and-competent breast tumor cells
-
Qin, H., Shao, Q., Igdoura, S.A., Alaoui-Jamali, M.A. and Laird, D.W. (2003) Lysosomal and proteasomal degradation play distinct roles in the life cycle of Cx43 in gap junctional intercellular communication-deficient and-competent breast tumor cells. J. Biol. Chem., 278, 30005-30014.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 30005-30014
-
-
Qin, H.1
Shao, Q.2
Igdoura, S.A.3
Alaoui-Jamali, M.A.4
Laird, D.W.5
-
16
-
-
84874227659
-
Latent TGF-beta binding protein 4 promotes elastic fiber assembly by interacting with fibulin-5
-
Noda, K., Dabovic, B., Takagi, K., Inoue, T., Horiguchi, M., Hirai, M., Fujikawa, Y., Akama, T.O., Kusumoto, K., Zilberberg, L. et al. (2013) Latent TGF-beta binding protein 4 promotes elastic fiber assembly by interacting with fibulin-5. Proc. Natl. Acad. Sci. USA, 110, 2852-2857.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 2852-2857
-
-
Noda, K.1
Dabovic, B.2
Takagi, K.3
Inoue, T.4
Horiguchi, M.5
Hirai, M.6
Fujikawa, Y.7
Akama, T.O.8
Kusumoto, K.9
Zilberberg, L.10
-
17
-
-
0037598870
-
Distinct endocytic pathways regulate TGF-beta receptor signalling and turnover
-
Di Guglielmo, G.M., Le Roy, C., Goodfellow, A.F. andWrana, J.L. (2003) Distinct endocytic pathways regulate TGF-beta receptor signalling and turnover. Nat. Cell Biol., 5, 410-421.
-
(2003)
Nat. Cell Biol
, vol.5
, pp. 410-421
-
-
Di Guglielmo, G.M.1
Le Roy, C.2
Goodfellow, A.F.3
Wrana, J.L.4
-
18
-
-
77954480793
-
TGF beta (transforming growth factor beta) receptor type III directs clathrin-mediated endocytosis of TGF beta receptor types I and II
-
McLean, S. and Di Guglielmo, G.M. (2010) TGF beta (transforming growth factor beta) receptor type III directs clathrin-mediated endocytosis of TGF beta receptor types I and II. Biochem. J., 429, 137-145.
-
(2010)
Biochem. J
, vol.429
, pp. 137-145
-
-
McLean, S.1
Di Guglielmo, G.M.2
-
19
-
-
0035918274
-
Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation
-
Ebisawa, T., Fukuchi, M., Murakami, G., Chiba, T., Tanaka, K., Imamura, T. and Miyazono, K. (2001) Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation. J. Biol. Chem., 276, 12477-12480.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 12477-12480
-
-
Ebisawa, T.1
Fukuchi, M.2
Murakami, G.3
Chiba, T.4
Tanaka, K.5
Imamura, T.6
Miyazono, K.7
-
20
-
-
0034517389
-
Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation
-
Kavsak, P., Rasmussen, R.K., Causing, C.G., Bonni, S., Zhu, H., Thomsen, G.H. andWrana, J.L. (2000) Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation. Mol. Cell., 6, 1365-1375.
-
(2000)
Mol. Cell
, vol.6
, pp. 1365-1375
-
-
Kavsak, P.1
Rasmussen, R.K.2
Causing, C.G.3
Bonni, S.4
Zhu, H.5
Thomsen, G.H.6
Wrana, J.L.7
-
21
-
-
79951850100
-
SNX25 regulates TGF-beta signaling by enhancing the receptor degradation
-
Hao, X., Wang, Y., Ren, F., Zhu, S., Ren, Y., Jia, B., Li, Y.P., Shi, Y. and Chang, Z. (2011) SNX25 regulates TGF-beta signaling by enhancing the receptor degradation. Cell. Signal., 23, 935-946.
-
(2011)
Cell. Signal
, vol.23
, pp. 935-946
-
-
Hao, X.1
Wang, Y.2
Ren, F.3
Zhu, S.4
Ren, Y.5
Jia, B.6
Li, Y.P.7
Shi, Y.8
Chang, Z.9
-
22
-
-
47349123215
-
Fibronectin and heparin binding domains of latent TGF-beta binding protein (LTBP)-4 mediate matrix targeting and cell adhesion
-
Kantola, A.K., Keski-Oja, J. and Koli, K. (2008) Fibronectin and heparin binding domains of latent TGF-beta binding protein (LTBP)-4 mediate matrix targeting and cell adhesion. Exp. Cell Res., 314, 2488-2500.
-
(2008)
Exp. Cell Res
, vol.314
, pp. 2488-2500
-
-
Kantola, A.K.1
Keski-Oja, J.2
Koli, K.3
-
23
-
-
84886286233
-
Syndecan-2 exerts antifibrotic effects by promoting caveolin-1-mediated transforming growth factor-beta receptor I internalization and inhibiting transforming growth factorbeta1 signaling
-
Shi, Y., Gochuico, B.R., Yu, G., Tang, X., Osorio, J.C., Fernandez, I.E., Risquez, C.F., Patel, A.S., Shi, Y., Wathelet, M.G. et al. (2013) Syndecan-2 exerts antifibrotic effects by promoting caveolin-1-mediated transforming growth factor-beta receptor I internalization and inhibiting transforming growth factorbeta1 signaling. Am. J. Respir. Crit. Care. Med., 188, 831-841.
-
(2013)
Am. J. Respir. Crit. Care. Med
, vol.188
, pp. 831-841
-
-
Shi, Y.1
Gochuico, B.R.2
Yu, G.3
Tang, X.4
Osorio, J.C.5
Fernandez, I.E.6
Risquez, C.F.7
Patel, A.S.8
Shi, Y.9
Wathelet, M.G.10
-
24
-
-
79956330132
-
Lessons on the pathogenesis of aneurysm from heritable conditions
-
Lindsay, M.E. and Dietz, H.C. (2011) Lessons on the pathogenesis of aneurysm from heritable conditions. Nature, 473, 308-316.
-
(2011)
Nature
, vol.473
, pp. 308-316
-
-
Lindsay, M.E.1
Dietz, H.C.2
-
25
-
-
75949103899
-
Integrin-TGF-beta crosstalk in fibrosis, cancer and wound healing
-
Margadant, C. and Sonnenberg, A. (2010) Integrin-TGF-beta crosstalk in fibrosis, cancer and wound healing. EMBO Rep., 11, 97-105.
-
(2010)
EMBO Rep
, vol.11
, pp. 97-105
-
-
Margadant, C.1
Sonnenberg, A.2
-
26
-
-
41649106542
-
Matrix elasticity, cytoskeletal tension, and TGF-beta: the insoluble and soluble meet
-
Wells, R.G. and Discher, D.E. (2008) Matrix elasticity, cytoskeletal tension, and TGF-beta: the insoluble and soluble meet. Sci. Signal., 1, pe13.
-
(2008)
Sci. Signal
, vol.1
-
-
Wells, R.G.1
Discher, D.E.2
-
27
-
-
85017832389
-
Latent transforming growth factor beta binding protein 4 enhances renal fibrosis in obstructive uropathy
-
Su, C.T., Huang, J.W., Chiang, C.K., Dabovic, B. and Urban, Z. (2014) Latent transforming growth factor beta binding protein 4 enhances renal fibrosis in obstructive uropathy. J. Am. Soc. Nephrol., 25, 732A.
-
(2014)
J. Am. Soc. Nephrol
, vol.25
, pp. 732A
-
-
Su, C.T.1
Huang, J.W.2
Chiang, C.K.3
Dabovic, B.4
Urban, Z.5
-
28
-
-
72849135317
-
Latent TGF-beta-binding protein 4 modifies muscular dystrophy in mice
-
Heydemann, A., Ceco, E., Lim, J.E., Hadhazy, M., Ryder, P., Moran, J.L., Beier, D.R., Palmer, A.A. and McNally, E.M. (2009) Latent TGF-beta-binding protein 4 modifies muscular dystrophy in mice. J. Clin. Invest., 119, 3703-3712.
-
(2009)
J. Clin. Invest
, vol.119
, pp. 3703-3712
-
-
Heydemann, A.1
Ceco, E.2
Lim, J.E.3
Hadhazy, M.4
Ryder, P.5
Moran, J.L.6
Beier, D.R.7
Palmer, A.A.8
McNally, E.M.9
-
29
-
-
84878390222
-
LTBP4 genotype predicts age of ambulatory loss in Duchenne muscular dystrophy
-
Flanigan, K.M., Ceco, E., Lamar, K.M., Kaminoh, Y., Dunn, D. M., Mendell, J.R., King, W.M., Pestronk, A., Florence, J.M., Mathews, K.D. et al. (2013) LTBP4 genotype predicts age of ambulatory loss in Duchenne muscular dystrophy. Ann. Neurol., 73, 481-488.
-
(2013)
Ann. Neurol
, vol.73
, pp. 481-488
-
-
Flanigan, K.M.1
Ceco, E.2
Lamar, K.M.3
Kaminoh, Y.4
Dunn, D.M.5
Mendell, J.R.6
King, W.M.7
Pestronk, A.8
Florence, J.M.9
Mathews, K.D.10
-
30
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
-
Livak, K.J. and Schmittgen, T.D. (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods, 25, 402-408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
31
-
-
0028328817
-
An assay for transforming growth factorbeta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct
-
Abe, M., Harpel, J.G., Metz, C.N., Nunes, I., Loskutoff, D.J. and Rifkin, D.B. (1994) An assay for transforming growth factorbeta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct. Anal. Biochem., 216, 276-284.
-
(1994)
Anal. Biochem
, vol.216
, pp. 276-284
-
-
Abe, M.1
Harpel, J.G.2
Metz, C.N.3
Nunes, I.4
Loskutoff, D.J.5
Rifkin, D.B.6
|