Surface display of an anti-DEC-205 single chain Fv fragment in Lactobacillus plantarum increases internalization and plasmid transfer to dendritic cells in vitro and in vivo

Microbial Cell Factories

Volumn 14, Issue 1, 2015, Pages

  Christophe, Michon ^a   Kuczkowska, Katarzyna ^b   Langella, Philippe ^a   Eijsink, Vincent G H ^b   Mathiesen, Geir ^b   Chatel, Jean Marc ^a  

^a UMR1319 MICALIS   (France)

^b NORWEGIAN UNIVERSITY OF LIFE SCIENCES   (Norway)

Author keywords

Cellular targeting; DEC 205; Dendritic cell; Drug delivery; Lactic acid bacteria; Surface display

Indexed keywords

SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; IMMUNOGLOBULIN VARIABLE REGION;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; BACTERIAL CELL; BACTERIAL CELL WALL; BACTERIAL STRAIN; CELL MEMBRANE; CELL SURFACE DISPLAY; CONTROLLED STUDY; COVALENT BOND; DENDRITIC CELL; DNA FRAGMENTATION; DNA SEQUENCE; DRUG DELIVERY SYSTEM; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; IMMUNOCOMPETENT CELL; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; LACTIC ACID BACTERIUM; LACTOBACILLUS PLANTARUM; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN EXPRESSION; SEQUENCE ANALYSIS; WESTERN BLOTTING; ANIMAL; BAGG ALBINO MOUSE; CELL CULTURE; EVALUATION STUDY; GENE EXPRESSION; GENE TRANSFER; GENETICS; HUMAN; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGY; METABOLISM; PLASMID; TRANSPORT AT THE CELLULAR LEVEL;

BACTERIA (MICROORGANISMS); EUKARYOTA; LACTOBACILLUS PLANTARUM; MUS;

ANIMALS; BIOLOGICAL TRANSPORT; CELLS, CULTURED; DENDRITIC CELLS; FEMALE; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; HUMANS; IMMUNOGLOBULIN VARIABLE REGION; LACTOBACILLUS PLANTARUM; MICE; MICE, INBRED BALB C; PLASMIDS; SINGLE-CHAIN ANTIBODIES;

EID: 84936764340     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/s12934-015-0290-9     Document Type: Article

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