NK-, NKT- and CD8-Derived IFNγ Drives Myeloid Cell Activation and Erythrophagocytosis, Resulting in Trypanosomosis-Associated Acute Anemia

PLoS Pathogens

Volumn 11, Issue 6, 2015, Pages

  Cnops, Jennifer ^a,b   De Trez, Carl ^a,b   Stijlemans, Benoit ^a,b   Keirsse, Jiri ^a,b   Kauffmann, Florence ^a,b   Barkhuizen, Mark ^c,d   Keeton, Roanne ^d   Boon, Louis ^e   Brombacher, Frank ^c,d   Magez, Stefan ^a,b,d  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^c INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

^d UNIVERSITY OF CAPE TOWN   (South Africa)

^e BIOCEROS   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 15; TUMOR NECROSIS FACTOR ALPHA;

ADOPTIVE TRANSFER; ANEMIA; ANIMAL CELL; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CD8+ T LYMPHOCYTE; CELL ACTIVATION; CELL LABELING; CONTROLLED STUDY; CYTOKINE PRODUCTION; ERYTHROCYTE COUNT; ERYTHROPHAGOCYTOSIS; FEMALE; FLOW CYTOMETRY; MOUSE; NAGANA; NATURAL KILLER CELL; NATURAL KILLER T CELL; NONHUMAN; PARASITEMIA; SIGNAL TRANSDUCTION; T CELL DEPLETION; TRYPANOSOMA; TRYPANOSOMIASIS; AFRICAN TRYPANOSOMIASIS; ANIMAL; C57BL MOUSE; CELL SEPARATION; COMPLICATION; DISEASE MODEL; ERYTHROCYTE; IMMUNOLOGY; KNOCKOUT MOUSE; PATHOLOGY; PHAGOCYTOSIS;

ANIMALIA; MURINAE; MUS;

ADOPTIVE TRANSFER; ANEMIA; ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL SEPARATION; DISEASE MODELS, ANIMAL; ERYTHROCYTES; FEMALE; FLOW CYTOMETRY; INTERFERON-GAMMA; KILLER CELLS, NATURAL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYELOID CELLS; NATURAL KILLER T-CELLS; PHAGOCYTOSIS; TRYPANOSOMIASIS, AFRICAN;

EID: 84936745321     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004964     Document Type: Article

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