The matricellular protein CCN1 controls retinal angiogenesis by targeting VEGF, Src homology 2 domain phosphatase-1 and Notch signaling

Development (Cambridge)

Volumn 142, Issue 13, 2015, Pages 2364-2374

  Chintala, Hemabindu ^a   Krupska, Izabela ^a   Yan, Lulu ^a   Lau, Lester ^b   Grant, Maria ^c   Chaqour, Brahim ^a,d  

^a STATE UNIVERSITY OF NEW YORK   (United States)

^b UNIVERSITY OF ILLINOIS   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d SUNY DOWNSTATE MEDICAL CENTER   (United States)

Author keywords

CCN1; Knockout mouse; Matricellular; Retinal angiogenesis; VEGF

Indexed keywords

CELL PROTEIN; CYSTEINE RICH PROTEIN 61; MITOGEN ACTIVATED PROTEIN KINASE; NOTCH RECEPTOR; PROTEIN TYROSINE PHOSPHATASE SHP 1; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 2; DLL4 PROTEIN, MOUSE; MEMBRANE PROTEIN; PTPN6 PROTEIN, MOUSE; SIGNAL PEPTIDE; VASCULOTROPIN A;

ALLELE; ANGIOGENESIS; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL ADHESION; CELL DENSITY; CELL FUNCTION; CELL GROWTH; CELL LOSS; CELL MIGRATION; CELL PROLIFERATION; CELL STIMULATION; CELL STRUCTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE DELETION; GENE INACTIVATION; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; IN SITU HYBRIDIZATION; LIMIT OF QUANTITATION; MOUSE; NONHUMAN; PERICYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; QUANTITATIVE ANALYSIS; REPORTER GENE; RETINA; RETINAL ANGIOGENESIS; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAIN; UPREGULATION; WESTERN BLOTTING; ANIMAL; ANTIBODY SPECIFICITY; C57BL MOUSE; CELL COUNT; CELL MOTION; CELL SHAPE; CYTOLOGY; DEFICIENCY; GENE SILENCING; GENETICS; METABOLISM; RETINA BLOOD VESSEL;

MUS;

ANIMALS; CELL COUNT; CELL MOVEMENT; CELL PROLIFERATION; CELL SHAPE; CYSTEINE-RICH PROTEIN 61; ENDOTHELIAL CELLS; GENE SILENCING; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; MICE, INBRED C57BL; NEOVASCULARIZATION, PHYSIOLOGIC; ORGAN SPECIFICITY; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 6; RECEPTORS, NOTCH; RETINAL VESSELS; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; SRC HOMOLOGY DOMAINS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR-2;

EID: 84936101172     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.121913     Document Type: Article

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