Arsenic causes aortic dysfunction and systemic hypertension in rats: Augmentation of angiotensin II signaling

Chemico-Biological Interactions

Volumn 237, Issue , 2015, Pages 104-114

  Waghe, Prashantkumar ^a   Sarath, Thengumpallil Sasindran ^a   Gupta, Priyanka ^a   Kandasamy, Kannan ^a   Choudhury, Soumen ^a   Kutty, Harikumar Sankaran ^a   Mishra, Santosh Kumar ^a   Sarkar, Souvendra Nath ^a  

^a INDIAN VETERINARY RESEARCH INSTITUTE   (India)

Author keywords

Angiotensin II; Arsenic; Hypertension; MAP kinase signaling; Reactive oxygen species; Vascular dysfunction

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II; ARSENIC; ARSENITE SODIUM; DIPEPTIDYL CARBOXYPEPTIDASE; DRINKING WATER; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN KINASE C; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; VASCULOTROPIN; SUPEROXIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AORTA DISEASE; ARTICLE; BLOOD PRESSURE MEASUREMENT; BLOOD SAMPLING; BLOOD VESSEL REACTIVITY; CONCENTRATION RESPONSE; CONTRACTION ASSAY; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXPOSURE; GENE EXPRESSION; HYPERTENSION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; OXIDATION REDUCTION STATE; PROTEIN BLOOD LEVEL; RAT; SIGNAL TRANSDUCTION; SMOOTH MUSCLE CONTRACTILITY; SYSTOLIC BLOOD PRESSURE; THORACIC AORTA; VASCULAR DISEASE; WESTERN BLOTTING; ANIMAL; AORTA; BLOOD; BLOOD PRESSURE; CHEMICALLY INDUCED; DRUG EFFECTS; METABOLISM; PATHOPHYSIOLOGY; UPREGULATION; WISTAR RAT;

RATTUS;

ANGIOTENSIN II; ANIMALS; AORTA; ARSENIC; BLOOD PRESSURE; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HYPERTENSION; MALE; NADPH OXIDASE; PEPTIDYL-DIPEPTIDASE A; RATS; RATS, WISTAR; RECEPTOR, ANGIOTENSIN, TYPE 1; SIGNAL TRANSDUCTION; SUPEROXIDES; UP-REGULATION;

EID: 84935873389     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2015.06.014     Document Type: Article

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