Allospecific CD4+ T cells retain effector function and are actively regulated by Treg cells in the context of transplantation tolerance

European Journal of Immunology

Volumn 45, Issue 7, 2015, Pages 2017-2027

  Chai, Jian Guo ^a,b   Ratnasothy, Kulachelvy ^a   Bucy, R Pat ^c   Noelle, Randolph J ^a,d   Lechler, Robert ^a   Lombardi, Giovanna ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c University of Alabama at Birmingham   (United States)

^d NORRIS COTTON CANCER CENTER   (United States)

Author keywords

CD4 T cells; CD40L blockade; Tolerance; Transplantation; Treg

Indexed keywords

ALLOANTIGEN; BREFELDIN A; CD40 LIGAND; CYTOKINE; INTERLEUKIN 2; IONOMYCIN; PHORBOL 13 ACETATE 12 MYRISTATE; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR FOXP3;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; GRAFT REJECTION; IMMUNE SYSTEM; IMMUNOLOGICAL TOLERANCE; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SKIN TRANSPLANTATION; T LYMPHOCYTE SUBPOPULATION; TRANSPLANTATION TOLERANCE; ALLOGRAFT; ANIMAL; GRAFT SURVIVAL; IMMUNOLOGY; KNOCKOUT MOUSE; TRANSGENIC MOUSE;

ADOPTIVE TRANSFER; ALLOGRAFTS; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; GRAFT SURVIVAL; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; T-LYMPHOCYTES, REGULATORY; TRANSPLANTATION TOLERANCE;

EID: 84935704676     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201545455     Document Type: Article

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