-
1
-
-
0032600630
-
The antimicrobial effects of extracts of Azadirachta indica (Neem) and Salvadora persica (Arak) chewing sticks
-
Almas, K. (1999) The antimicrobial effects of extracts of Azadirachta indica (Neem) and Salvadora persica (Arak) chewing sticks. Indian. J. Dent. Res. 10, 3-6.
-
(1999)
Indian. J. Dent. Res.
, vol.10
, pp. 3-6
-
-
Almas, K.1
-
2
-
-
11444249412
-
Septic shock
-
Annane, D., Bellissant, E. and Cavaillon, J. M. (2005) Septic shock. Lancet. 365, 63-78.
-
(2005)
Lancet
, vol.365
, pp. 63-78
-
-
Annane, D.1
Bellissant, E.2
Cavaillon, J.M.3
-
3
-
-
0033838948
-
Immune depression in polymicrobial sepsis: The role of necrotic (injured) tissue and endotoxin
-
Ayala, A., Song, G. Y., Chung, C. S., Redmond, K. M. and Chaudry, I. H. (2000) Immune depression in polymicrobial sepsis: the role of necrotic (injured) tissue and endotoxin. Crit. Care Med. 28, 2949-2955.
-
(2000)
Crit. Care Med.
, vol.28
, pp. 2949-2955
-
-
Ayala, A.1
Song, G.Y.2
Chung, C.S.3
Redmond, K.M.4
Chaudry, I.H.5
-
4
-
-
0033140086
-
'In vitro' antiviral activity of neem (Azadirachta indica. A. Juss) leaf extract against group B coxsackieviruses
-
Badam, L., Joshi, S. P. and Bedekar, S. S. (1999) 'In vitro' antiviral activity of neem (Azadirachta indica. A. Juss) leaf extract against group B coxsackieviruses. J. Commun. Dis. 31, 79-90.
-
(1999)
J. Commun. Dis.
, vol.31
, pp. 79-90
-
-
Badam, L.1
Joshi, S.P.2
Bedekar, S.S.3
-
5
-
-
0035826096
-
Effi cacy and safety of recombinant human activated protein C for severe sepsis
-
Recombinant human protein C Worldwide Evaluation in Severe Sepsis (PROWESS) study group
-
Bernard, G. R., Vincent, J. L., Laterre, P. F., LaRosa, S. P., Dhainaut, J. F., Lopez-Rodriguez, A., Steingrub, J. S., Garber, G. E., Helterbrand, J. D., Ely, E. W. and Fisher, C. J. Jr; Recombinant human protein C Worldwide Evaluation in Severe Sepsis (PROWESS) study group (2001). Effi cacy and safety of recombinant human activated protein C for severe sepsis. N. Engl. J. Med. 344, 699-709.
-
(2001)
N. Engl. J. Med.
, vol.344
, pp. 699-709
-
-
Bernard, G.R.1
Vincent, J.L.2
Laterre, P.F.3
Larosa, S.P.4
Dhainaut, J.F.5
Lopez-Rodriguez, A.6
Steingrub, J.S.7
Garber, G.E.8
Helterbrand, J.D.9
Ely, E.W.10
Fisher Jr., C.J.11
-
6
-
-
18344384146
-
Tumor necrosis factor-alpha-induced caspase activation mediates endotoxin-related cardiac dysfunction
-
Carlson, D. L., Willis, M S., White, D. J., Horton, J. W. and Giroir, B. P. (2005) Tumor necrosis factor-alpha-induced caspase activation mediates endotoxin-related cardiac dysfunction. Crit. Care Med. 33, 1021-1028
-
(2005)
Crit. Care Med.
, vol.33
, pp. 1021-1028
-
-
Carlson, D.L.1
Willis M, S.2
White, D.J.3
Horton, J.W.4
Giroir, B.P.5
-
7
-
-
0032915853
-
Inhibition of TPA-induced protein kinase C and transcription activator protein-1 binding activities by theafl avin-3,3'-digallate from black tea in NIH3T3 cells
-
Chen, Y. C., Liang, Y. C., Lin-Shiau, S. Y., Ho, C. T. and Lin, J. K. (1999) Inhibition of TPA-induced protein kinase C and transcription activator protein-1 binding activities by theafl avin-3,3'-digallate from black tea in NIH3T3 cells. J. Agric. Food Chem. 47, 1416-1421.
-
(1999)
J. Agric. Food Chem.
, vol.47
, pp. 1416-1421
-
-
Chen, Y.C.1
Liang, Y.C.2
Lin-Shiau, S.Y.3
Ho, C.T.4
Lin, J.K.5
-
8
-
-
79955666815
-
Small molecules in treatment of sepsis
-
Hu, Y., Xie, G. H., Chen, Q. X. and Fang, X. M. (2011) Small molecules in treatment of sepsis. Curr. Drug Targets. 12, 256-262.
-
(2011)
Curr. Drug Targets
, vol.12
, pp. 256-262
-
-
Hu, Y.1
Xie, G.H.2
Chen, Q.X.3
Fang, X.M.4
-
9
-
-
33645097021
-
A novel cyclohexene derivative, ethyl (6R)-6-[N-(2-Chloro-4-fl uorophenyl)sulfamoyl] cyclohex-1-ene-1-carboxylate (TAK-242), selectively inhibits tolllike receptor 4-mediated cytokine production through suppression of intracellular signaling
-
Ii, M., Matsunaga, N., Hazeki, K., Nakamura, K., Takashima, K., Seya, T., Hazeki, O., Kitazaki, T. and Iizawa, Y. (2006) A novel cyclohexene derivative, ethyl (6R)-6-[N-(2-Chloro-4-fl uorophenyl)sulfamoyl] cyclohex-1-ene-1-carboxylate (TAK-242), selectively inhibits tolllike receptor 4-mediated cytokine production through suppression of intracellular signaling. Mol. Pharmacol. 69, 88-95.
-
(2006)
Mol. Pharmacol.
, vol.69
, pp. 88-95
-
-
Ii, M.1
Matsunaga, N.2
Hazeki, K.3
Nakamura, K.4
Takashima, K.5
Seya, T.6
Hazeki, O.7
Kitazaki, T.8
Iizawa, Y.9
-
10
-
-
41149138938
-
Benzoxathiole derivative blocks lipopolysaccharide-induced nuclear factor-kappaB activation and nuclear factor-kappaB-regulated gene transcription through inactivating inhibitory kappaB kinase beta
-
Kim, B. H., Roh, E., Lee, H. Y., Lee, I. J., Ahn, B., Jung, S. H., Leem H., Hanm S. B. and Kimm Y. (2008) Benzoxathiole derivative blocks lipopolysaccharide-induced nuclear factor-kappaB activation and nuclear factor-kappaB-regulated gene transcription through inactivating inhibitory kappaB kinase beta. Mol. Pharmacol. 73, 1309-1318.
-
(2008)
Mol. Pharmacol.
, vol.73
, pp. 1309-1318
-
-
Kim, B.H.1
Roh, E.2
Lee, H.Y.3
Lee, I.J.4
Ahn, B.5
Jung, S.H.6
Leem, H.7
Hanm, S.B.8
Kimm, Y.9
-
11
-
-
33846462057
-
Regulation of lipopolysaccharide-induced inducible nitric-oxide synthase expression through the nuclear factor-kappaB pathway and interferon-beta/tyrosine kinase 2/Janus tyrosine kinase 2-signal transducer and activator of transcription-1 signaling cascades by 2-naphthylethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (THI 53), a new synthetic isoquinoline alkaloid
-
Kim, H. J., Tsoyi, K., Heo, J. M., Kang, Y. J., Park, M. K., Lee, Y. S., Lee, J. H., Seo, H. G., Yun-Choi, H. S. and Chang, K. C. (2007) Regulation of lipopolysaccharide-induced inducible nitric-oxide synthase expression through the nuclear factor-kappaB pathway and interferon-beta/tyrosine kinase 2/Janus tyrosine kinase 2-signal transducer and activator of transcription-1 signaling cascades by 2-naphthylethyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (THI 53), a new synthetic isoquinoline alkaloid. J. Pharmacol. Exp. Ther. 320, 782-789.
-
(2007)
J. Pharmacol. Exp. Ther.
, vol.320
, pp. 782-789
-
-
Kim, H.J.1
Tsoyi, K.2
Heo, J.M.3
Kang, Y.J.4
Park, M.K.5
Lee, Y.S.6
Lee, J.H.7
Seo, H.G.8
Yun-Choi, H.S.9
Chang, K.C.10
-
12
-
-
0028999596
-
Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase
-
MacMicking, J. D., Nathan, C., Hom, G., Chartrain, N., Fletcher, D. S., Trumbauer, M., Stevens, K., Xie, Q. W., Sokol, K., Hutchinson, N., et al. (1995) Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthase. Cell. 81, 641-650.
-
(1995)
Cell
, vol.81
, pp. 641-650
-
-
Macmicking, J.D.1
Nathan, C.2
Hom, G.3
Chartrain, N.4
Fletcher, D.S.5
Trumbauer, M.6
Stevens, K.7
Xie, Q.W.8
Sokol, K.9
Hutchinson, N.10
-
13
-
-
0030839255
-
Pathobiology of lipopolysaccharide
-
Mayeux, P. R. (1997) Pathobiology of lipopolysaccharide. J. Toxicol. Environ. Health. 51, 415-435.
-
(1997)
J. Toxicol. Environ. Health
, vol.51
, pp. 415-435
-
-
Mayeux, P.R.1
-
14
-
-
0025041309
-
Structureactivity relationships of polymethoxyfl avones and other fl avonoids as inhibitors of non-enzymic lipid peroxidation
-
Mora, A., Payá, M., Ríos, J. L. and Alcaraz, M. J. (1990) Structureactivity relationships of polymethoxyfl avones and other fl avonoids as inhibitors of non-enzymic lipid peroxidation. Biochem. Pharmacol. 40, 793-797.
-
(1990)
Biochem. Pharmacol.
, vol.40
, pp. 793-797
-
-
Mora, A.1
Payá, M.2
Ríos, J.L.3
Alcaraz, M.J.4
-
15
-
-
13944275512
-
Identifi cation from a positional scanning peptoid library of in vivo active compounds that neutralize bacterial endotoxins
-
Mora, P., Masip, I., Cortés, N., Marquina, R., Merino, R., Merino, J., Carbonell, T., Mingarro, I., Messeguer, A. and Pérez-Payá, E. (2005) Identifi cation from a positional scanning peptoid library of in vivo active compounds that neutralize bacterial endotoxins. J. Med. Chem. 48, 1265-1268.
-
(2005)
J. Med. Chem.
, vol.48
, pp. 1265-1268
-
-
Mora, P.1
Masip, I.2
Cortés, N.3
Marquina, R.4
Merino, R.5
Merino, J.6
Carbonell, T.7
Mingarro, I.8
Messeguer, A.9
Pérez-Payá, E.10
-
16
-
-
34447260517
-
Protection from endotoxic shock by EVK-203, a novel alkylpolyamine sequestrant of lipopolysaccharide
-
Nguyen, T. B., Adisechan, A. K., Suresh Kumar, E. V., Balakrishna, R., Kimbrell, M. R., Miller, K. A., Datta, A. and David, S. A. (2007) Protection from endotoxic shock by EVK-203, a novel alkylpolyamine sequestrant of lipopolysaccharide. Bioorg. Med. Chem. 15, 5694-5709.
-
(2007)
Bioorg. Med. Chem.
, vol.15
, pp. 5694-5709
-
-
Nguyen, T.B.1
Adisechan, A.K.2
Suresh Kumar, E.V.3
Balakrishna, R.4
Kimbrell, M.R.5
Miller, K.A.6
Datta, A.7
David, S.A.8
-
17
-
-
0019378734
-
Anti-infl ammatory and antipyretic activities of Azadirachta indica
-
Okpanyi, S. N. and Ezeukwu, G. C. (1981) Anti-infl ammatory and antipyretic activities of Azadirachta indica. Planta. Med. 41, 34-39.
-
(1981)
Planta. Med.
, vol.41
, pp. 34-39
-
-
Okpanyi, S.N.1
Ezeukwu, G.C.2
-
18
-
-
0032415375
-
Isolation of antioxidant principle from Azadirachta seed kernels: Determination of its role on plant lipoxygenases
-
Rao, A. D., Devi, K. N. and Thyagaraju, K. (1998) Isolation of antioxidant principle from Azadirachta seed kernels: determination of its role on plant lipoxygenases. J. Enzyme. Inhib. 14, 85-96.
-
(1998)
J. Enzyme. Inhib.
, vol.14
, pp. 85-96
-
-
Rao, A.D.1
Devi, K.N.2
Thyagaraju, K.3
-
19
-
-
50149111428
-
Targeting QseC signaling and virulence for antibiotic development
-
Rasko, D. A., Moreira, C. G., Li de, R., Reading, N. C., Ritchie, J. M., Waldor, M. K., Williams, N., Taussig, R., Wei, S., Roth, M., Hughes, D. T., Huntley, J. F., Fina, M. W., Falck, J. R. and Sperandio, V. (2008) Targeting QseC signaling and virulence for antibiotic development. Science. 321, 1078-1080.
-
(2008)
Science
, vol.321
, pp. 1078-1080
-
-
Rasko, D.A.1
Moreira, C.G.2
Li de, R.3
Reading, N.C.4
Ritchie, J.M.5
Waldor, M.K.6
Williams, N.7
Taussig, R.8
Wei, S.9
Roth, M.10
Hughes, D.T.11
Huntley, J.F.12
Fina, M.W.13
Falck, J.R.14
Sperandio, V.15
-
20
-
-
0037141773
-
In vitro and in vivo inhibitory activities of rutin, wogonin, and quercetin on lipopolysaccharide-induced nitric oxide and prostaglandin E(2) production
-
Shen, S. C., Lee, W. R., Lin, H. Y., Huang, H. C., Ko, C. H., Yang, L. L. and Chen, Y. C. (2002) In vitro and in vivo inhibitory activities of rutin, wogonin, and quercetin on lipopolysaccharide-induced nitric oxide and prostaglandin E(2) production. Eur. J. Pharmacol. 446, 187-194.
-
(2002)
Eur. J. Pharmacol.
, vol.446
, pp. 187-194
-
-
Shen, S.C.1
Lee, W.R.2
Lin, H.Y.3
Huang, H.C.4
Ko, C.H.5
Yang, L.L.6
Chen, Y.C.7
-
21
-
-
34547615202
-
Bound to shock: Protection from lethal endotoxemic shock by a novel, nontoxic, alkylpolyamine lipopolysaccharide sequestrant
-
Sil, D., Shrestha, A., Kimbrell, M. R., Nguyen, T. B., Adisechan, A. K., Balakrishna, R., Abbo, B. G., Malladi, S., Miller, K. A., Short, S., Cromer, J. R., Arora, S., Datta, A. and David, S. A. (2007) Bound to shock: protection from lethal endotoxemic shock by a novel, nontoxic, alkylpolyamine lipopolysaccharide sequestrant. Antimicrob. Agents. Chemother. 51, 2811-2819.
-
(2007)
Antimicrob. Agents. Chemother.
, vol.51
, pp. 2811-2819
-
-
Sil, D.1
Shrestha, A.2
Kimbrell, M.R.3
Nguyen, T.B.4
Adisechan, A.K.5
Balakrishna, R.6
Abbo, B.G.7
Malladi, S.8
Miller, K.A.9
Short, S.10
Cromer, J.R.11
Arora, S.12
Datta, A.13
David, S.A.14
-
22
-
-
48649102396
-
Prophylaxis of lipopolysaccharideinduced shock by alpha-galactosylceramide
-
Sireci, G., La Manna, M. P., Di Liberto, D., Lo Dico, M., Taniguchi, M., Dieli, F. and Salerno, A. (2008) Prophylaxis of lipopolysaccharideinduced shock by alpha-galactosylceramide. J. Leukoc. Biol. 84, 550-560.
-
(2008)
J. Leukoc. Biol.
, vol.84
, pp. 550-560
-
-
Sireci, G.1
la Manna, M.P.2
di Liberto, D.3
lo Dico, M.4
Taniguchi, M.5
Dieli, F.6
Salerno, A.7
-
23
-
-
0034884419
-
Flavonoids protect mice from two types of lethal shock induced by endotoxin
-
Takahashi, K., Morikawa, A., Kato, Y., Sugiyama, T., Koide, N., Mu, M. M., Yoshida, T. and Yokochi, T. (2001) Flavonoids protect mice from two types of lethal shock induced by endotoxin. FEMS. Immunol. Med. Microbiol. 31, 29-33, 2001.
-
(2001)
FEMS. Immunol. Med. Microbiol.
, vol.31
, Issue.2001
, pp. 29-33
-
-
Takahashi, K.1
Morikawa, A.2
Kato, Y.3
Sugiyama, T.4
Koide, N.5
Mu, M.M.6
Yoshida, T.7
Yokochi, T.8
-
24
-
-
0030843135
-
Nitric oxide and septic shock
-
Thiemermann, C. (1997) Nitric oxide and septic shock. Gen. Pharmacol. 29, 159-166.
-
(1997)
Gen. Pharmacol.
, vol.29
, pp. 159-166
-
-
Thiemermann, C.1
-
25
-
-
0032928083
-
Nitric oxide in septic shock
-
Titheradge, M. A. (1999) Nitric oxide in septic shock. Biochim. Biophys. Acta. 1411, 437-455.
-
(1999)
Biochim. Biophys. Acta.
, vol.1411
, pp. 437-455
-
-
Titheradge, M.A.1
-
26
-
-
74049106566
-
Activated protein C for sepsis
-
Toussaint, S., and Gerlach, H. (2009) Activated protein C for sepsis. N. Engl. J. Med. 361, 2646-2652.
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 2646-2652
-
-
Toussaint, S.1
Gerlach, H.2
-
27
-
-
0028244816
-
Tumor necrosis factor: A pleiotropic cytokine and therapeutic target
-
Tracey, K. J. and Cerami, A. (1994) Tumor necrosis factor: a pleiotropic cytokine and therapeutic target. Annu. Rev. Med. 45, 491-503.
-
(1994)
Annu. Rev. Med.
, vol.45
, pp. 491-503
-
-
Tracey, K.J.1
Cerami, A.2
-
28
-
-
0038447123
-
Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock
-
Van Amersfoort, ES., Van Berkel, T. J. and Kuiper, J. (2003) Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock. Clin. Microbiol. Rev. 16, 379-414.
-
(2003)
Clin. Microbiol. Rev.
, vol.16
, pp. 379-414
-
-
van Amersfoort, E.S.1
van Berkel, T.J.2
Kuiper, J.3
-
29
-
-
16244377733
-
The role of tumour necrosis factor in the kinetics of lipopolysaccharide-mediated neutrophil priming in whole blood
-
van Leeuwen, H. J., Van Der Tol, M., Van Strijp, J. A., Verhoef, J. and van Kessel, K. P. (2005) The role of tumour necrosis factor in the kinetics of lipopolysaccharide-mediated neutrophil priming in whole blood. Clin. Exp. Immunol. 140, 65-72.
-
(2005)
Clin. Exp. Immunol.
, vol.140
, pp. 65-72
-
-
van Leeuwen, H.J.1
van der Tol, M.2
van Strijp, J.A.3
Verhoef, J.4
van Kessel, K.P.5
-
30
-
-
0031733244
-
Effects of endotoxic shock in several functions of murine peritoneal macrophages
-
Víctor, V. M., Miñanom M., Guayerbasm N., Del Ríom M., Medinam S. and De la Fuente. M. (1998) Effects of endotoxic shock in several functions of murine peritoneal macrophages. Mol. Cell Biochem. 189, 25-31.
-
(1998)
Mol. Cell Biochem.
, vol.189
, pp. 25-31
-
-
Víctor, V.M.1
Miñanom, M.2
Guayerbasm, N.3
del Ríom, M.4
Medinam, S.5
De la Fuente., M.6
-
31
-
-
0029035476
-
Altered immune responses in mice lacking inducible nitric oxide synthase
-
Wei, X. Q., Charles, I. G., Smith, A., Ure, J., Feng, G. J., Huang, F. P., Xu, D., Muller, W., Moncada, S. and Liew, F. Y. (1995) Altered immune responses in mice lacking inducible nitric oxide synthase. Nature. 375, 408-411.
-
(1995)
Nature
, vol.375
, pp. 408-411
-
-
Wei, X.Q.1
Charles, I.G.2
Smith, A.3
Ure, J.4
Feng, G.J.5
Huang, F.P.6
Xu, D.7
Muller, W.8
Moncada, S.9
Liew, F.Y.10
-
32
-
-
0037532629
-
Effect of Azadirachta indica on paracetamolinduced hepatic damage in albino rats
-
Yanpallewar, S. U., Sen, S., Tapas, S., Kumar, M., Raju, S. S. and Acharya, S. B. (2003) Effect of Azadirachta indica on paracetamolinduced hepatic damage in albino rats. Phytomedicine. 10, 391-396.
-
(2003)
Phytomedicine
, vol.10
, pp. 391-396
-
-
Yanpallewar, S.U.1
Sen, S.2
Tapas, S.3
Kumar, M.4
Raju, S.S.5
Acharya, S.B.6
-
33
-
-
77955705446
-
Effects of enrofl oxacin, fl unixin meglumine and dexamethasone on disseminated intravascular coagulation, cytokine levels and adenosine deaminase activity in endotoxaemia in rats
-
Yazar, E., Bulbul, A., Avci, G. E., Er, A., Uney, K., Elmas, M. and Tras, B. (2010) Effects of enrofl oxacin, fl unixin meglumine and dexamethasone on disseminated intravascular coagulation, cytokine levels and adenosine deaminase activity in endotoxaemia in rats. Acta. Vet. Hung. 58, 357-367.
-
(2010)
Acta. Vet. Hung.
, vol.58
, pp. 357-367
-
-
Yazar, E.1
Bulbul, A.2
Avci, G.E.3
Er, A.4
Uney, K.5
Elmas, M.6
Tras, B.7
|