Calcium plus vitamin D supplementation during the third trimester of pregnancy in adolescents accustomed to low calcium diets does not affect infant bone mass at early lactation in a randomized controlled trial

Journal of Nutrition

Volumn 145, Issue 7, 2015, Pages 1515-1523

  Diogenes, Maria Eduarda L ^a,b   Bezerra, Flávia F ^c   Rezende, Elaine P ^c   Donangelo, Carmen M ^a,d  

^a FEDERAL UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^b INSTITUTO NACIONAL DE CÂNCER   (Brazil)

^c STATE UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^d UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

Author keywords

Adolescent mothers; Calcium plus vitamin D supplementation; Fetal skeletal growth; Infant bone mass; Lactation; Pregnancy

Indexed keywords

25 HYDROXYVITAMIN D; CALCIUM; COLECALCIFEROL; PLACEBO; CALCIUM INTAKE; VITAMIN D;

ADOLESCENT; ADOLESCENT MOTHER; ADOLESCENT PREGNANCY; ADULT; ANTHROPOMETRY; ARTICLE; BIOMETRY; BODY WEIGHT; BONE AREA; BONE DENSITY; BONE MASS; BONE MINERAL; BRAZILIAN; CALCIUM INTAKE; COMPARATIVE STUDY; CONTROLLED STUDY; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FEMUR NECK; GESTATION PERIOD; HIP; HUMAN; INVESTIGATIVE PROCEDURES; LACTATION; LUMBAR SPINE; MEDICAL ASSESSMENT; MEDICAL RECORD; NEWBORN; NORMAL HUMAN; PUERPERIUM; RANDOMIZED CONTROLLED TRIAL; THIRD TRIMESTER PREGNANCY; VITAMIN SUPPLEMENTATION; ADMINISTRATION AND DOSAGE; BRAZIL; BREAST FEEDING; DIET SUPPLEMENTATION; DRUG EFFECTS; FETUS DEVELOPMENT; INFANT; LUMBAR VERTEBRA; METABOLISM; PHOTON ABSORPTIOMETRY; PREGNANCY; SINGLE BLIND PROCEDURE;

ABSORPTIOMETRY, PHOTON; ADOLESCENT; BONE DENSITY; BRAZIL; BREAST FEEDING; CALCIUM, DIETARY; DIETARY SUPPLEMENTS; FEMALE; FEMUR NECK; FETAL DEVELOPMENT; HUMANS; INFANT; LACTATION; LUMBAR VERTEBRAE; PREGNANCY; PREGNANCY TRIMESTER, THIRD; SINGLE-BLIND METHOD; VITAMIN D;

EID: 84935491965     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.114.208140     Document Type: Article

References (35)

1. Olausson H, Goldberg GR, Laskey MA, Schoenmakers I, Jarjou LM, Prentice A. Calcium economy in human pregnancy and lactation. Nutr Res Rev 2012;25:40-67.
2. Prentice A. Micronutrients and the bone mineral content of mother, fetus and newborn. J Nutr 2003;133:1693S-9S.
3. Chan GM, McElligott K, McNaught T, Gill G. Effects of dietary calcium intervention on adolescent mothers and newborns: a randomized controlled trial. Obstet Gynecol 2006;108:565-71.
4. Chang SC, O'Brien KO, Nathanson MS, Caulfield LE, Mancini J, Witter FR. Fetal femur length is influenced by maternal dairy intake in pregnant African American adolescents. Am J Clin Nutr 2003;77: 1248-54.
5. Young BE, McNanley TJ, Cooper EM, McIntyre AW, Witter F, Harris ZL, O'Brien KO. Maternal vitamin D status and calcium intake interact to affect fetal skeletal growth in utero in pregnant adolescents. Am J Clin Nutr 2012;95:1103-12.
6. Abalos E, Merialdi M, Wojdyla D, Carroli G, Campodónico L, Yao SE, Gonzalez R, Deter R, Villar J, Van Look P. Effects of calcium supplementation of fetal growth in mothers with deficient calcium intake: a randomized controlled trial. Paediatr Perinat Epidemiol 2010; 24:53-62.
7. Abdel-Aleem H, Merialdi M, Elsnosy ED, Elsedfy GO, Abdel-Aleem MA, Villar J. The effect of calcium supplementation during pregnancy on fetal and infant growth: a nested randomized controlled trial within WHO calcium supplementation Trial. J Matern Fetal Neonatal Med 2009;22:94-100.
8. Jarjou LM, Prentice A, Sawo Y, Laskey MA, Bennett J, Goldberg GR, Cole TJ. Randomized, placebo-controlled, calcium supplementation study in pregnant Gambian women: effects on breast-milk calcium concentrations and infant birth weight, growth, and bone mineral accretion in the first year of life. Am J Clin Nutr 2006;83: 657-66.
9. Koo WW, Walters JC, Esterlitz J, Levine RJ, Bush AJ, Sibai B. Maternal calcium supplementation and fetal bone mineralization. Obstet Gynecol 1999;94:577-82.
10. Villar J, Abdel-Aleem H, Merialdi M, Mathai M, Ali M, Zavaleta N, Purwar M, Hofmeyr GJ, Ngoc NTN, Campodonico L, et al. World Health Organization randomized trial of calcium supplementation among low calcium intake pregnant women. Am J Obstet Gynecol 2006;194:639-49.
11. Goldberg GR, Jarjou LMA, Cole TJ, Prentice A. Randomized, placebo-controlled, calcium supplementation trial in pregnant Gambian women accustomed to a low calcium intake: effects on maternal blood pressure and infant growth. Am J Clin Nutr 2013;98: 972-82.
12. Jarjou LMA, Laskey MA, Sawo Y, Goldberg GR, Cole TJ, Prentice A. Effect of calcium supplementation in pregnancy on maternal bone outcomes in women with a low calcium intake. Am J Clin Nutr 2010;92:450-7.
13. Jarjou LMA, Sawo Y, Goldberg GR, Laskey MA, Cole TJ, Prentice A. Unexpected long-term effects of calcium supplementation in pregnancy on maternal bone outcomes in women with a low calcium intake: a follow-up study. Am J Clin Nutr 2013;98:723-30.
14. Done SL. Fetal and neonatal bone health: update on bone growth and manifestations in health and disease. Pediatr Radiol 2012;42: Suppl 1: S158-76.
15. Kovacs CS. Bone development in the fetus and neonate: role of the calciotropic hormones. Curr Osteoporos Rep 2011;9:274-83.
16. Diogenes ME, Bezerra FF, Rezende EP, Taveira MF, Pinhal I, Donangelo CM. Effect of calcium plus vitamin D supplementation during pregnancy in Brazilian adolescent mothers: a randomized, placebocontrolled trial. Am J Clin Nutr 2013;98:82-91.
17. Bezerra FF, Laboissière FP, King JC, Donangelo CM. Pregnancy and lactation affect markers of calcium and bone metabolism differently in adolescent and adult women with low calcium intakes. J Nutr 2002;132:2183-7.
18. Bezerra FF, Mendonça LM, Lobato EC, O'Brien KO, Donangelo CM. Bone mass is recovered from lactation to postweaning in adolescent mother with low calcium intakes. Am J Clin Nutr 2004;80: 1322-6.
19. Bezerra FF, Mendonça L, Donangelo CM. Bone mass is associated with vitamin D status in lactating adolescent mothers. FASEB J 2008;22: 458.2 (abstract).
20. WHO, FAO. Vitamin and mineral requirements in human nutrition, 2nd edition: Geneva, Switzerland: WHO. 2004.
21. WHO, Indicators for assessing breast-feeding practices. WHO document WHO/CDD/SER/91.14. Geneva, Switzerland: WHO. 1991.
22. Núcleo de Estudos e Pesquisas em Alimentação NEPA-UNICAMP. Tabela brasileira de composição de alimentos: Campinas, Brazil: NEPA/UNICAMP. 2006.
23. Hadlock FP, Harrist RB, Martinez-Poyer J. In utero analysis of fetal growth: a sonographic weight standard. Radiology 1991;181: 129-33.
24. WHO Multicentre Growth Reference Study Group. WHO child growth standards: length/height-for-age, weight-for-age, weight-for-length, weight-for-height and body mass index-for-age: methods and development: Geneva: WHO. 2006.
25. Lubchenco LO, Hansman C, Boyd E. Intrauterine growth in length and head circumference as estimated from live births at gestational ages from 26 to 42 weeks. Pediatrics 1966;37:403-8.
26. The International Society for Clinical Densitometry (ISCD). Official positions adult and pediatric. Skeletal Health Assessment In Children from Infancy to Adolescence, 2014; 17-20.
27. WHO. Training course on child growth assessment: Geneva: WHO. 2008.
28. Brasil. Ministério da Saúde. Protocolos do Sistema de Vigilância Alimentar e Nutricional-SISVAN na assistência á saúde: Brasília: Ministério da Saúde. 2008.
29. Araujo Júnior E, Martins Santana EF, Martins WP, Júnior JE, Ruano R, Pires CR, Filho SM. Reference charts of fetal biometric parameters in 31,476 Brazilian singleton pregnancies. J Ultrasound Med 2014;33: 1185-91.
30. Buppasiri P, Lumbiganon P, Thinkhamrop J, Ngamjarus C, Laopaiboon M. Calcium supplementation (other than for preventing or treating hypertension) for improving pregnancy and infant outcomes. Cochrane Database Syst Rev 2011;10:CD007079.
31. Imdad A, Bhutta ZA. Effects of calcium supplementation during pregnancy on maternal, fetal and birth outcomes. Paediatr Perinat Epidemiol 2012;26:138-52.
32. Koo W. Study of the effect of calcium supplementation during pregnancy on the risk of preterm birth or low birth weight infants is inconclusive. Evid Based Med 2012;17:186-7.
33. Land C, Schoenau E. Fetal and postnatal bone development: reviewing the role of mechanical stimuli and nutrition. Best Pract Res Clin Endocrinol Metab 2008;22:107-18.
34. Dror DK, King JC, Fung EB, Van Loan MD, Gertz ER, Allen LH. Evidence of associations between feto-maternal vitamin D status, cord parathyroid hormone and bone-specific alkaline phosphatase, and newborn whole body bone mineral content. Nutrients 2012;4: 68-77.
35. Czech-Kowalska J, Latka-Grot J, Bulsiewicz D, Jaworski M, Pludowski P, Wygledowska G, Chazan B, Pawlus B, Zochowska A, Borszewska-Kornacka MK, et al. Impact of vitamin D supplementation during lactation on vitamin D status and body composition of mother-infant pairs: a MAVID randomized controlled trial. PLoS ONE 2014;9: e107708.