Impact of vitamin D supplementation during lactation on vitamin D status and body composition of mother-infant pairs: A MAVID randomized controlled trial

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Czech Kowalska, Justyna ^a   Latka Grot, Julita ^a   Bulsiewicz, Dorota ^a   Jaworski, Maciej ^a   Pludowski, Pawel ^a   Wygledowska, Grazyna ^b   Chazan, Bogdan ^c   Pawlus, Beata ^c   Zochowska, Anna ^d   Borszewska Kornacka, Maria K ^e   Karczmarewicz, Elzbieta ^a   Czekuc Kryskiewicz, Edyta ^a   Dobrzanska, Anna ^a  

^a CHILDREN'S MEMORIAL HEALTH INSTITUTE   (Poland)

^b Laboratory of Nuclear Medicine   (Poland)

^c Holy Family Clinic of Gynecology and Obstetrics in Warsaw   (Poland)

^d Public Hospital   (Poland)

^e MEDICAL UNIVERSITY OF WARSAW   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

25 HYDROXYVITAMIN D; CALCIUM; COLECALCIFEROL; PARATHYROID HORMONE; PLACEBO; VITAMIN;

ADULT; ARTICLE; BODY COMPOSITION; BONE MASS; BREAST FEEDING; CALCIUM BLOOD LEVEL; CALCIUM URINE LEVEL; CONTROLLED STUDY; DENSITOMETRY; FAT MASS; FEMALE; HUMAN; INFANT; LACTATION; MATERNAL NUTRITION; MOTHER CHILD RELATION; NUTRITIONAL STATUS; OUTCOME ASSESSMENT; PARATHYROID HORMONE BLOOD LEVEL; PREVALENCE; RANDOMIZED CONTROLLED TRIAL; VITAMIN BLOOD LEVEL; VITAMIN D DEFICIENCY; VITAMIN INTAKE; VITAMIN SUPPLEMENTATION; BIRTH WEIGHT; BLOOD; BODY MASS; BONE DENSITY; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; MALE; NEWBORN; PREGNANCY; PROSPECTIVE STUDY; TREATMENT OUTCOME;

ADULT; BIRTH WEIGHT; BODY COMPOSITION; BODY MASS INDEX; BONE DENSITY; BREAST FEEDING; CALCIUM; CHOLECALCIFEROL; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INFANT, NEWBORN; LACTATION; MALE; PARATHYROID HORMONE; PREGNANCY; PROSPECTIVE STUDIES; TREATMENT OUTCOME; VITAMINS;

EID: 84907219443     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0107708     Document Type: Article

References (53)

1. Pludowski P, Holick MF, Pilz S, Wagner C.L., Hollis BW, et al. (2013) Vitamin D effects on musculoskeletal health, immunity, autoimmunity, cardiovascular disease, cancer, fertility, pregnancy, dementia and mortality-a review of recent evidence. Autoimmun Rev 12: 976-989.
2. Specker BL, Tsang RC, Ho M.L. (1991) Changes in calcium homeostasis over the first year postpartum: effect of lactation and weaning. Obstet Gynecol 78: 56-62.
3. Milman N, Hvas AM, Bergholt T. (2011) Vitamin D status during normal pregnancy and postpartum. A longitudinal study in 141 Danish women. J Perinat Med 40: 57-61.
4. Narchi H, Kochiyil J, Zayed R., Abdulrazzak W, Agarwal M. (2010) Maternal vitamin D status throughout and after pregnancy. J Obstet Gynaecol 30: 137-142.
5. Wawrzyniak A, Hamulka J, Gorzel K. (2009) [Assessment of vitamins and minerals intake with supplements during breast-feeding]. Rocz Panstw Zakl Hig 60: 353-356.
6. Czech-Kowalska J., Dobrzanska A, Gruszfeld D., Zochowska A, Malinowska E, et al (2008) High prevalence of neonatal vitamin D deficiency - rationale for reevaluation of vitamin D supplementation during pregnancy. Arch Perinatal Med 14: 18-22.
7. Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon C.M., Hanley DA, et al. (2011) Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 96: 1911-1930.
8. Basile LA, Taylor SN, Wagner C.L., Horst RL, Hollis B.W. (2006) The effect of high-dose vitamin D supplementation on serum vitamin D levels and milk calcium concentration in lactating women and their infants. Breastfeed Med 1: 27-35.
9. Wagner CL, Hulsey TC, Fanning D, Ebeling M., Hollis B.W. (2006) High-dose vitamin D3 supplementation in a cohort of breastfeeding mothers and their infants: a 6-month follow-up pilot study. Breastfeed Med 1: 59-70.
10. Saadi HF, Dawodu A, Afandi B., Zayed R, Benedict S, et al (2009) Effect of combined maternal and infant vitamin D supplementation on vitamin D status of exclusively breastfed infants. Matern Child Nutr 5: 25-32.
11. Oberhelman SS, Meekins ME, Fischer P.R., Lee BR, Singh RJ, et al. (2013) Maternal Vitamin D Supplementation to Improve the Vitamin D Status of Breast-fed Infants: A Randomized Controlled Trial. Mayo Clin Proc 88: 1378-1387. doi:1310.1016/j.mayocp.2013.1309.1012.
12. IOM (2011) Dietary Reference Intakes for Calcium and Vitamin D. Washington, DC: The National Academies Press.
13. Paxton GA, Teale GR, Nowson C.A., Mason RS, McGrath JJ, et al. (2013) Vitamin D and health in pregnancy, infants, children and adolescents in Australia and New Zealand: a position statement. Med J Aust 198: 142-143.
14. Godel J, Irvine J, Onyett H., Saylor K, Schroter H, et al (2007) Vitamin D supplementation: Recommendations for Canadian mothers and infants. Paediatrics & Child Health: 583-589.
15. Department of Health (2012) Vitamin D - advice on supplements for at risk groups - letter from UK Chief Medical Officers. Available: www.gov.uk/government/publications/vitamin-d-advice-on-supplements-for-at-risk-groups/.
16. Płudowski P, Karczmarewicz E., Bayer M, Carter G, Chlebna-Sokoí D, et al. (2013) Practical guidelines for the supplementation of vitamin D and the treatment of deficits in Central Europe - recommended vitamin D intakes in the general population and groups at risk of vitamin D deficiency. Endokrynol Pol 64: 319-327.
17. Heaney RP, Davies KM, Chen T.C., Holick MF, Barger-Lux MJ (2003) Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol. Am J Clin Nutr 77: 204-210.
18. Costa ML, Krupa FG, Rehder P.M., Sousa MH, Costa-Paiva L, et al. (2012) Forearm bone mineral density changes during postpartum and the effects of breastfeeding, amenorrhea, body mass index and contraceptive use. Osteoporos Int 23: 1691-1698.
19. Moller UK, Vieth Streym S, Mosekilde L, Rejnmark L. (2012) Changes in bone mineral density and body composition during pregnancy and postpartum. A controlled cohort study. Osteoporos Int 23: 1213-1223.
20. Kalkwarf HJ (1999) Hormonal and dietary regulation of changes in bone density during lactation and after weaning in women. J Mammary Gland Biol Neoplasia 4: 319-329.
21. Kalkwarf HJ, Specker BL, Bianchi D.C., Ranz J., Ho M. (1997) The effect of calcium supplementation on bone density during lactation and after weaning. N Engl J Med 337: 523-528.
22. Kovacs CS (2012) The role of vitamin D in pregnancy and lactation: insights from animal models and clinical studies. Annu Rev Nutr 32: 97-123.
23. Møller UK, Streym S, Mosekilde L, Heickendorff L, Flyvbjerg A, et al. (2013) Changes in calcitropic hormones, bone markers and insulin-like growth factor I (IGF-I) during pregnancy and postpartum: a controlled cohort study. Osteoporos Int 24: 1307-1320.
24. Kull M, Kallikorm R, Lember M. (2012) Vitamin D as a possible independent predictor of bone mineral density in Estonian adults: a cross-sectional population-based study. Intern Med J 42: e89-94.
25. Al-Shaar L., Nabulsi M, Maalouf J., El-Rassi R, Vieth R, et al (2013) Effect of vitamin D replacement on hip structural geometry in adolescents: a randomized controlled trial. Bone 56: 296-303.
26. Gallo S, Comeau K, Vanstone C., Agellon S, Sharma A, et al (2013) Effect of different dosages of oral vitamin D supplementation on vitamin D status in healthy, breastfed infants: a randomized trial. JAMA 309: 1785-1792.
27. Specker BL, Tsang RC, Hollis B.W. (1985) Effect of race and diet on human-milk vitamin D and 25-hydroxyvitamin D. Am J Dis Child 139: 1134-1137.
28. Czech-Kowalska J., Dobrzanska A, Janowska J., Pleskaczynska A, Niezgoda A, et al (2004) [Neonatal vitamin D status and calcium-phosphorus homeostasis in the third week of life]. Med Wieku Rozwoj 8: 115-124.
29. Dawson-Hughes B., Heaney RP, Holick M.F., Lips P., Meunier PJ, et al. (2005) Estimates of optimal vitamin D status. Osteoporos Int 16: 713-716.
30. Gillings D, Koch G. (1991) The Application of the Principle of Intention - to - Treat to the Analysis of Clinical Trials. Drug Inf J 25: 411-424.
31. Hollis BW, Wagner C.L. (2004) Vitamin D requirements during lactation: highdose maternal supplementation as therapy to prevent hypovitaminosis D for both the mother and the nursing infant. Am J Clin Nutr 80: 1752S-1758S.
32. Rosen CJ, Abrams SA, Aloia J.F., Brannon PM, Clinton SK, et al. (2012) IOM committee members respond to Endocrine Society vitamin D guideline. J Clin Endocrinol Metab 97: 1146-1152. doi:1110.1210/jc.2011-2218. Epub 2012 Mar1122.
33. Holick MF, Binkley NC, Bischoff-Ferrari HA, Gordon C.M., Hanley DA, et al. (2012) Guidelines for preventing and treating vitamin D deficiency and insufficiency revisited. J Clin Endocrinol Metab 97: 1153-1158.
34. Hollis BW, Wagner C.L. (2013) Vitamin D and pregnancy: skeletal effects, nonskeletal effects, and birth outcomes. Calcif Tissue Int 92: 128-139. doi:110.1007/s00223-00012-09607-00224. Epub 02012 May 00224.
35. Hollis BW, Johnson D, Hulsey T.C., Ebeling M., Wagner C.L. (2011) Vitamin D supplementation during pregnancy: double-blind, randomized clinical trial of safety and effectiveness. J Bone Miner Res 26: 2341-2357.
36. Garland CF, French CB, Baggerly L.L., Heaney R.P. (2011) Vitamin D supplement doses and serum 25-hydroxyvitamin D in the range associated with cancer prevention. Anticancer Res 31: 607-611.
37. Heaney RP, Armas LA, French C. (2013) All-source basal vitamin D inputs are greater than previously thought and cutaneous inputs are smaller. J Nutr 143: 571-575.
38. Ala-Houhala M., Koskinen T, Terho A., Koivula T, Visakorpi J. (1986) Maternal compared with infant vitamin D supplementation. Arch Dis Child 61: 1159-1163.
39. Hollis BW, Wagner C.L. (2004) Assessment of dietary vitamin D requirements during pregnancy and lactation. Am J Clin Nutr 79: 717-726.
40. Saadi HF, Dawodu A, Afandi B.O., Zayed R., Benedict S, et al. (2007) Efficacy of daily and monthly high-dose calciferol in vitamin D-deficient nulliparous and lactating women. Am J Clin Nutr 85: 1565-1571.
41. Anderson DM, Hollis BW, LeVine B.R., Pittard W.B. (1988) Dietary assessment of maternal vitamin D intake and correlation with maternal and neonatal serum vitamin D concentrations at delivery. J Perinatol 8: 46-48.
42. Wagner CL, Taylor SN, Johnson D.D., Hollis B.W. (2012) The role of vitamin D in pregnancy and lactation: emerging concepts. Womens Health (Lond Engl) 8: 323-340. doi:310.2217/whe.2212.2217.
43. McDonnell SL, French CB, Heaney R.P. (2013) Quantifying the food sources of basal vitamin d input. J Steroid Biochem Mol Biol.
44. Czech-Kowalska J., Pludowski P, Dobrzanska A., Kryskiewicz E, Karczmarewicz E, et al (2012) Impact of vitamin D supplementation on markers of bone mineral metabolism in term infants. Bone 51: 781-786.
45. Greer FR (2008) 25-Hydroxyvitamin D: functional outcomes in infants and young children. Am J Clin Nutr 88: 529S-533S.
46. Cranney A, Horsley T, O'Donnell S, Weiler H, Puil L., et al. (2007) Effectiveness and safety of vitamin D in relation to bone health. Evid Rep Technol Assess (Full Rep): 1-235.
47. Sai AJ, Walters RW, Fang X, Gallagher J.C. (2011) Relationship between vitamin D, parathyroid hormone, and bone health. J Clin Endocrinol Metab 96: E436-446.
48. Bowyer L, Catling-Paull C, Diamond T., Homer C, Davis G, et al (2009) Vitamin D, PTH and calcium levels in pregnant women and their neonates. Clin Endocrinol (Oxf) 70: 372-377.
49. Young BE, McNanley TJ, Cooper E.M., McIntyre AW, Witter F, et al. (2012) Maternal vitamin D status and calcium intake interact to affect fetal skeletal growth in utero in pregnant adolescents. Am J Clin Nutr 95: 1103-1112. doi:1110.3945/ajcn.1111.023861. Epub 022012 Apr 023864.
50. Dror DK, King JC, Fung E.B., Van Loan MD, Gertz ER, et al. (2012) Evidence of associations between feto-maternal vitamin D status, cord parathyroid hormone and bone-specific alkaline phosphatase, and newborn whole body bone mineral content. Nutrients 4: 68-77. doi:10.3390/nu4020068. Epub 4022012 Feb 4020066.
51. Greco EA, Francomano D, Fornari R., Marocco C, Lubrano C, et al (2013) Negative association between trunk fat, insulin resistance and skeleton in obese women. World J Diabetes 4: 31-39.
52. Laskey M, Price R, Khoo B., Prentice A. (2011) Proximal femur structural geometry changes during and following lactation. Bone 48: 755-759.
53. Fudge NJ, Kovacs C.S. (2010) Pregnancy up-regulates intestinal calcium absorption and skeletal mineralization independently of the vitamin D receptor. Endocrinology 151: 886-895.