Silence of MACC1 expression by RNA interference inhibits proliferation, invasion and metastasis, and promotes apoptosis in U251 human malignant glioma cells

Molecular Medicine Reports

Volumn 12, Issue 3, 2015, Pages 3423-3431

  Sun, Longfeng ^a   Li, Gang ^b   Dai, Bing ^a   Tan, Wei ^a   Zhao, Hongwen ^a   Li, Xiaofei ^a   Wang, Aiping ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b LIAONING CANCER HOSPITAL AND INSTITUTE   (China)

Author keywords

Apoptosis; Invasion; Metastasis; Metastasis associated in colon cancer 1; Proliferation; U251 cells

Indexed keywords

CASPASE 3; CYCLIN D1; CYCLIN E; GELATINASE A; GELATINASE B; METASTASIS ASSOCIATED IN COLON CANCER 1; ONCOPROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG; MACC1 PROTEIN, HUMAN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR;

APOPTOSIS; ARTICLE; BIOASSAY; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; COLONY FORMATION; CONTROLLED STUDY; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; GLIOBLASTOMA; GLIOBLASTOMA CELL LINE; HOECHST STAINING; HUMAN; HUMAN CELL; MACC1 GENE; METASTASIS; MOLECULAR MECHANICS; MTT ASSAY; ONCOGENE; RNA INTERFERENCE; STAINING; TRANSWELL ASSAY; TUMOR GROWTH; WESTERN BLOTTING; WOUND HEALING ASSAY; BRAIN TUMOR; CELL CYCLE CHECKPOINT; GENETICS; GLIOMA; METABOLISM; PATHOLOGY; SECONDARY; TUMOR CELL LINE; TUMOR INVASION;

APOPTOSIS; BRAIN NEOPLASMS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL PROLIFERATION; GENE KNOCKDOWN TECHNIQUES; GLIOMA; HUMANS; NEOPLASM INVASIVENESS; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRANSCRIPTION FACTORS;

EID: 84935455600     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.3886     Document Type: Article

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