Tyrosol suppresses allergic inflammation by inhibiting the activation of phosphoinositide 3-kinase in mast cells

PLoS ONE

Volumn 10, Issue 6, 2015, Pages

  Je, In Gyu ^a   Kim, Duk Sil ^b   Kim, Sung Wan ^b   Lee, Soyoung ^a   Lee, Hyun Shik ^c   Park, Eui Kyun ^c   Khang, Dongwoo ^d   Kim, Sang Hyun ^a  

^a Kyungpook National University School of Medicine   (South Korea)

^b CHA University   (South Korea)

^c Kyungpook National University   (South Korea)

^d Gachon University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

BETA N ACETYLHEXOSAMINIDASE; CALCIUM; DEXAMETHASONE; GALLIC ACID; HISTAMINE; I KAPPA B KINASE INHIBITOR; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; INTERLEUKIN 1BETA; INTERLEUKIN 4; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE LYN; PROTEIN KINASE SYK; TUMOR NECROSIS FACTOR ALPHA; TYROSOL; 4-HYDROXYPHENYLETHANOL; ANTIALLERGIC AGENT; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; CYTOKINE; MESSENGER RNA; PHENETHYL ALCOHOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIALLERGIC ACTIVITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL ACTIVATION; CELL VIABILITY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG MECHANISM; DRUG TARGETING; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME RELEASE; HISTAMINE RELEASE; HYPOTHERMIA; IN VITRO STUDY; IN VIVO STUDY; MALE; MAST CELL; MAST CELL DEGRANULATION; NONHUMAN; PASSIVE SKIN ANAPHYLAXIS; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SYSTEMIC ANAPHYLAXIS; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; APOPTOSIS; CELL CULTURE; CELL PROLIFERATION; DEGRANULATION; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYMOLOGY; GENETICS; HYPERSENSITIVITY; IMMUNOLOGY; INFLAMMATION; METABOLISM; MOUSE; PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

ANIMALIA;

ANIMALS; ANTI-ALLERGIC AGENTS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; APOPTOSIS; BLOTTING, WESTERN; CELL DEGRANULATION; CELL PROLIFERATION; CELLS, CULTURED; CYTOKINES; ENZYME ACTIVATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; HYPERSENSITIVITY; INFLAMMATION; MALE; MAST CELLS; MICE; PASSIVE CUTANEOUS ANAPHYLAXIS; PHENYLETHYL ALCOHOL; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84935429527     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0129829     Document Type: Article

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