Stereoselective Synthesis of Chiral β-Fluoro α-Amino Acids via Pd(II)-Catalyzed Fluorination of Unactivated Methylene C(sp3)-H Bonds: Scope and Mechanistic Studies

Journal of the American Chemical Society

Volumn 137, Issue 25, 2015, Pages 8219-8226

  Zhang, Qi ^a   Yin, Xue Song ^a   Chen, Kai ^a   Zhang, Shuo Qing ^a   Shi, Bing Feng ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CATALYSIS; FLUORINATION; FLUORINE; HALOGENATION; MECHANICS; PALLADIUM COMPOUNDS; REACTION INTERMEDIATES; STEREOCHEMISTRY; STEREOSELECTIVITY; SYNTHESIS (CHEMICAL);

CHEMICAL EQUATIONS; COMPLEX MOLECULES; DIASTEREOSELECTIVE FLUORINATION; INNERSPHERE MECHANISM; MECHANISTIC STUDIES; MILD REACTION CONDITIONS; REDUCTIVE ELIMINATION; STEREOSELECTIVE SYNTHESIS;

PALLADIUM;

ALPHA AMINO ACID; CARBENE; PALLADIUM; AMINO ACID; METHANE;

ARTICLE; CATALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; FLUORINATION; HYDROGEN BOND; REACTION ANALYSIS; SYNTHESIS; CHEMISTRY; HALOGENATION; STEREOISOMERISM;

AMINO ACIDS; CATALYSIS; HALOGENATION; METHANE; MODELS, MOLECULAR; PALLADIUM; STEREOISOMERISM;

EID: 84935114978     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.5b03989     Document Type: Article

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