Enhanced physical stabilization of fenofibrate nanosuspensions via wet co-milling with a superdisintegrant and an adsorbing polymer

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 94, Issue , 2015, Pages 372-385

  Azad, Mohammad ^a   Afolabi, Afolawemi ^a   Bhakay, Anagha ^a   Leonardi, Jonathan ^a   Davé, Rajesh ^a   Bilgili, Ecevit ^a  

^a NEW JERSEY INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Drug nanoparticles; Physical stability; Superdisintegrants; Surfactant free; Swelling; Wet media milling

Indexed keywords

CROSCARMELLOSE SODIUM; CROSPOVIDONE; FENOFIBRATE; HYDROXYPROPYLMETHYLCELLULOSE; NANOPARTICLE; POLYMER; STARCH GLYCOLATE SODIUM; ANTILIPEMIC AGENT; CARBOXYMETHYLCELLULOSE; EXCIPIENT; POVIDONE; STARCH; SUSPENSION;

ADSORPTION; ARTICLE; CHEMICAL PROCEDURES; DIFFERENTIAL SCANNING CALORIMETRY; DRUG STABILITY; DRUG STRUCTURE; LASER DIFFRACTION; PHYSICAL CHEMISTRY; SCANNING ELECTRON MICROSCOPY; VISCOMETRY; WET CO MILLING; X RAY DIFFRACTION; ANALOGS AND DERIVATIVES; CHEMISTRY; KINETICS; PHARMACEUTICS; PROCEDURES; SUSPENSION;

ADSORPTION; CARBOXYMETHYLCELLULOSE SODIUM; DRUG STABILITY; EXCIPIENTS; FENOFIBRATE; HYPOLIPIDEMIC AGENTS; HYPROMELLOSE DERIVATIVES; KINETICS; NANOPARTICLES; POVIDONE; STARCH; SUSPENSIONS; TECHNOLOGY, PHARMACEUTICAL;

EID: 84935072441     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2015.05.028     Document Type: Article

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