Histopathological study of the effects of a single intratracheal instillation of surface active agents on lung in rats

Journal of Toxicological Sciences

Volumn 25, Issue 1, 2000, Pages 49-55

  Suzuki, Masami ^a   Machida, Minora ^a   Adachi, Kenji ^a   Otabe, Kouji ^a   Sugimoto, Tetsuro ^a   Hayashi, Masahiro ^b   Awazu, Shoji ^c  

^a CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^b TOKYO UNIVERSITY OF SCIENCE   (Japan)

^c TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

Absorption enhancer; Acute inflammation; Lung injury; Polyoxyethylene 9 lauryl ether; Sodium glycocholate; Surface active agent

Indexed keywords

DRUG ADDITIVE; GLYCOCHOLATE SODIUM; PEPTIDE DERIVATIVE; POLIDOCANOL; SURFACTANT;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRONCHUS INJURY; CONTROLLED STUDY; DESQUAMATION; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG INSTILLATION; DRUG PENETRATION; HISTOPATHOLOGY; LUNG ALVEOLUS EPITHELIUM; LUNG EDEMA; LUNG FIBROSIS; LUNG HEMORRHAGE; LUNG INFILTRATE; LUNG INJURY; LUNG TOXICITY; MALE; NONHUMAN; RAT;

ANIMALIA; BRONCHUS;

EID: 0034074385     PISSN: 03881350     EISSN: 18803989     Source Type: Journal    
DOI: 10.2131/jts.25.49     Document Type: Article

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