Comprehensive analysis of microRNA-regulated protein interaction network reveals the tumor suppressive role of microRNA-149 in human hepatocellular carcinoma via targeting AKT-mTOR pathway

Molecular Cancer

Volumn 13, Issue 1, 2014, Pages

  Zhang, Yanqiong ^a   Guo, Xiaodong ^b   Xiong, Lu ^c   Yu, Lingxiang ^b   Li, Zhiwei ^b   Guo, Qiuyan ^a   Li, Zhiyan ^b   Li, Boan ^b   Lin, Na ^a  

^a INSTITUTE OF CHINESE MATERIA MEDICA   (China)

^b BEIJING 302 HOSPITAL   (China)

^c Zhongguancun Hospital of Beijing   (China)

Author keywords

AKT mTOR pathway; Hepatocellular carcinoma; microRNA 149; microRNA regulated protein interaction network; Prognosis

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; MICRORNA; MICRORNA 122; MICRORNA 124; MICRORNA 149; MICRORNA 184; MICRORNA 302D; MICRORNA 708; PROTEIN AKT3; PROTEIN KINASE; PROTEIN KINASE B; PROTEIN KINASE B BETA; SMALL UNTRANSLATED RNA; UNCLASSIFIED DRUG; MIRN149 MICRORNA, HUMAN; MTOR PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE;

ADULT; ARTICLE; CANCER PROGNOSIS; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; ONLINE SYSTEM; PROTEIN EXPRESSION; PROTEIN INTERACTION; REGULATORY MECHANISM; RNA HYBRIDIZATION; SIGNAL TRANSDUCTION; VALIDATION STUDY; DISEASE COURSE; DOWN REGULATION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; HEPG2 CELL LINE; LIVER TUMOR; MIDDLE AGED; PROCEDURES; PROTEIN PROTEIN INTERACTION; TUMOR CELL LINE;

CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; CELL PROLIFERATION; DISEASE PROGRESSION; DOWN-REGULATION; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MALE; MICRORNAS; MIDDLE AGED; PROTEIN INTERACTION MAPS; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84935007615     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-13-253     Document Type: Article

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