Galactosylated chitosan-grafted multiwall carbon nanotubes for pH-dependent sustained release and hepatic tumor-targeted delivery of doxorubicin in vivo

Colloids and Surfaces B: Biointerfaces

Volumn 133, Issue , 2015, Pages 314-322

  Qi, Xiaole ^a   Rui, Yao ^a   Fan, Yuchao ^a   Chen, Haiyan ^a   Ma, Ning ^a   Wu, Zhenghong ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Carbon nanotubes; Doxorubicin; Galactosylated chitosan; PH dependent release; Tumor targeting

Indexed keywords

BIOCOMPATIBILITY; CARBON; CHITIN; CHITOSAN; CYTOTOXICITY; DRUG PRODUCTS; MOBILE SECURITY; MULTIWALLED CARBON NANOTUBES (MWCN); TUMORS; YARN;

ANTI-TUMOR ACTIVITIES; CELLULAR UPTAKE EFFICIENCY; DOXORUBICIN; GALACTOSYLATED CHITOSAN; INTRAVENOUS ADMINISTRATION; MAXIMUM TOLERATED DOSE; PH-DEPENDENT RELEASE; TUMOR TARGETING;

CARBON NANOTUBES;

CHITOSAN; DOXORUBICIN; MULTI WALLED NANOTUBE; NANOCARRIER; ANTINEOPLASTIC ANTIBIOTIC; CARBON NANOTUBE; GALACTOSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOCOMPATIBILITY; CELL MEDIATED CYTOTOXICITY; CELL TRANSPORT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG SYNTHESIS; FLUORESCENCE ANALYSIS; HEPG2 CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; MALE; MAXIMUM TOLERATED DOSE; MOUSE; NONHUMAN; OXIDATION; PH; PRIORITY JOURNAL; SUSTAINED DRUG RELEASE; TRANSMISSION ELECTRON MICROSCOPY; VASCULAR DISEASE; ANIMAL; CHEMISTRY; LIVER NEOPLASMS; NUDE MOUSE; PATHOLOGY;

MUS;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CHITOSAN; DOXORUBICIN; GALACTOSE; HEP G2 CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; LIVER NEOPLASMS; MALE; MICE; MICE, NUDE; NANOTUBES, CARBON;

EID: 84934952823     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2015.06.003     Document Type: Article

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