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Volumn 11, Issue 2, 2010, Pages 686-697

Development and in vitro characterization of galactosylated low molecular weight chitosan nanoparticles bearing doxorubicin

Author keywords

Doxorubicin; HCC targeting; Low molecular weight chitosan; Nanoparticles

Indexed keywords

ASIALOGLYCOPROTEIN RECEPTOR; CHITOSAN; CYANAMIDE; DOXORUBICIN; LACTOBIONIC ACID; NANOPARTICLE; POLYMER; ANTINEOPLASTIC AGENT; DRUG VEHICLE; EXCIPIENT; GALACTOSE; NANOCAPSULE;

EID: 77954816831     PISSN: None     EISSN: 15309932     Source Type: Journal    
DOI: 10.1208/s12249-010-9422-z     Document Type: Article
Times cited : (44)

References (49)
  • 1
    • 33749474970 scopus 로고    scopus 로고
    • Looking at liver cancer
    • Ann P. Looking at liver cancer. Nursing. 2006;36:52-5.
    • (2006) Nursing , vol.36 , pp. 52-55
    • Ann, P.1
  • 2
    • 0034856294 scopus 로고    scopus 로고
    • Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference. European association for the study of the liver
    • Bruix J, Sherman M, Llovet JM, Beaugrand M, Lencioni R, Burroughs AK et al. Clinical management of hepatocellular carcinoma. Conclusions of the Barcelona-2000 EASL conference. European Association for the Study of the Liver. J Hepatol. 2001;35:421-30.
    • (2001) J. Hepatol. , vol.35 , pp. 421-430
    • Bruix, J.1    Sherman, M.2    Llovet, J.M.3    Beaugrand, M.4    Lencioni, R.5    Burroughs, A.K.6
  • 3
    • 0036187648 scopus 로고    scopus 로고
    • Long-term stability of heat-humidity cured cellulose acetate phthalate coated beads
    • DOI 10.1016/S0939-6411(01)00234-X, PII S093964110100234X
    • Liu J, Williams RO. Long-term stability of heat-humidity cured cellulose acetate phthalate coated beads. Eur J Pharm Biopharm. 2002;53:167-73. (Pubitemid 34189790)
    • (2002) European Journal of Pharmaceutics and Biopharmaceutics , vol.53 , Issue.2 , pp. 167-173
    • Liu, J.1    Williams III, R.O.2
  • 4
    • 0037308133 scopus 로고    scopus 로고
    • Systematic review of randomized trials for unresectable hepatocellular carcinoma: Chemoembolization improves survival
    • Llovet JM, Bruix J. Systematic review of randomized trials for unresectable hepatocellular carcinoma: chemoembolization improves survival. Hepatology. 2003;37:429-42.
    • (2003) Hepatology , vol.37 , pp. 429-442
    • Llovet, J.M.1    Bruix, J.2
  • 5
    • 0242331206 scopus 로고    scopus 로고
    • Drug resistance reversal-are we getting closer?
    • Baird RD, Kaye SB. Drug resistance reversal-are we getting closer? Eur J Cancer. 2003;39:2450-61.
    • (2003) Eur. J. Cancer , vol.39 , pp. 2450-2461
    • Baird, R.D.1    Kaye, S.B.2
  • 6
    • 0028416237 scopus 로고
    • Targeting of drugs to various blood cell types using (neo-) glycoproteins, antibodies and other protein carriers
    • Molema G, Meijer D K F. Targeting of drugs to various blood cell types using (neo-) glycoproteins, antibodies and other protein carriers. Adv Drug Deliv Rev. 1994;14:25-50.
    • (1994) Adv. Drug Deliv. Rev. , vol.14 , pp. 25-50
    • Molema, G.1    Meijer, D.K.F.2
  • 7
    • 0026711121 scopus 로고
    • Drug targeting systems for antiviral agents: Options and limitations
    • Meijer D K F, Jansen RW, Molema G. Drug targeting systems for antiviral agents: options and limitations. Antivir Res. 1992;18:215-58.
    • (1992) Antivir Res. , vol.18 , pp. 215-258
    • Meijer, D.K.F.1    Jansen, R.W.2    Molema, G.3
  • 9
    • 0031055830 scopus 로고    scopus 로고
    • Phase II study of liposomal doxorubicin in refractory ovarian cancer: Antitumor activity and toxicity modification by liposomal encapsulation
    • Muggia FM, Hainsworth JD, Jeffers S. Phase II study of liposomal doxorubicin in refractory ovarian cancer: antitumor activity and toxicity modification by liposomal encapsulation. J Clin Oncol. 1997;15:987-93.
    • (1997) J. Clin. Oncol. , vol.15 , pp. 987-993
    • Muggia, F.M.1    Hainsworth, J.D.2    Jeffers, S.3
  • 11
    • 0030927574 scopus 로고    scopus 로고
    • Reversion of multidrug resistance with polyalkylcyanoacrylate nanoparticles: Towards a mechanism of action
    • De Colin V A C, Dubernet C, Nemati F, Soma E, Appel M, Ferte J et al. Reversion of multidrug resistance with polyalkylcyanoacrylate nanoparticles: towards a mechanism of action. Br J Cancer. 1997;76:198-205.
    • (1997) Br. J. Cancer , vol.76 , pp. 198-205
    • De Colin, V.A.C.1    Dubernet, C.2    Nemati, F.3    Soma, E.4    Appel, M.5    Ferte, J.6
  • 12
    • 0028036158 scopus 로고
    • Enhanced cytotoxicity of doxorubicin encapsulated in polyisohexylcyanoacrylate nanospheres against multidrug-resistant tumour cells in culture
    • Bennis S, Chapey C, Robert J, Couvreur P. Enhanced cytotoxicity of doxorubicin encapsulated in polyisohexylcyanoacrylate nanospheres against multidrug-resistant tumour cells in culture. Eur J Cancer. 1994;30:89-93.
    • (1994) Eur. J. Cancer , vol.30 , pp. 89-93
    • Bennis, S.1    Chapey, C.2    Robert, J.3    Couvreur, P.4
  • 13
    • 0016322758 scopus 로고
    • The role of surface carbohydrates in the hepatic recognition and transport of circulating glycoproteins
    • Ashwell G, Morell AG. The role of surface carbohydrates in the hepatic recognition and transport of circulating glycoproteins. Adv Enzymol Relat Areas Mol Biol. 1974;41:99-128.
    • (1974) Adv. Enzymol. Relat. Areas Mol. Biol. , vol.41 , pp. 99-128
    • Ashwell, G.1    Morell, A.G.2
  • 14
    • 33646348981 scopus 로고    scopus 로고
    • Blending chitosan with polycaprolactone: Effects on physicochemical and antibacterial properties
    • Sarasam AR, Krishnaswamy RK, Madihally SV. Blending chitosan with polycaprolactone: effects on physicochemical and antibacterial properties. Biomacromolecules. 2006;7:1131-8.
    • (2006) Biomacromolecules , vol.7 , pp. 1131-1138
    • Sarasam, A.R.1    Krishnaswamy, R.K.2    Madihally, S.V.3
  • 15
    • 84934563825 scopus 로고
    • Life after death for empty shells
    • Nicol S. Life after death for empty shells. New Sci. 1991;129:46-8.
    • (1991) New Sci. , vol.129 , pp. 46-48
    • Nicol, S.1
  • 17
    • 0034000909 scopus 로고    scopus 로고
    • Simple preparation of half N-acetylated chitosan highly soluble in water and aqueous organic solvents
    • Kubota N, Tatsumoto N, Sano T, Toya K. Simple preparation of half N-acetylated chitosan highly soluble in water and aqueous organic solvents. Carbohydr Res. 2000;324:268-74.
    • (2000) Carbohydr Res. , vol.324 , pp. 268-274
    • Kubota, N.1    Tatsumoto, N.2    Sano, T.3    Toya, K.4
  • 18
    • 0030572089 scopus 로고    scopus 로고
    • Chitosan film acylation and effects on biodegradability
    • Xu J, McCarthy SP, Fross RA, Kaplan DL. Chitosan film acylation and effects on biodegradability. Macromolecules. 1996;29:3436-40.
    • (1996) Macromolecules , vol.29 , pp. 3436-3440
    • Xu, J.1    McCarthy, S.P.2    Fross, R.A.3    Kaplan, D.L.4
  • 19
    • 0027048490 scopus 로고
    • Preparation of methyl 2, 3-di-O-mesyl-4, 6-thioanhydro-alpha-D- galactopyranoside and methyl 2-O-mesyl-4, 6-thioanhydro-alpha-D-gulopyranoside
    • Pantaleone D, Yalpani M, Scollar M. Preparation of methyl 2, 3-di-O-mesyl-4, 6-thioanhydro-alpha-D-galactopyranoside and methyl 2-O-mesyl-4, 6-thioanhydro-alpha-D-gulopyranoside. Carbohydr Res. 1992;237:325-32.
    • (1992) Carbohydr Res. , vol.237 , pp. 325-332
    • Pantaleone, D.1    Yalpani, M.2    Scollar, M.3
  • 20
    • 0026040111 scopus 로고
    • Determination of the Mark-Houwink equation for chitosans with different degrees of deacetylation
    • Wang W, Bo S, Li S, Qin W. Determination of the Mark-Houwink equation for chitosans with different degrees of deacetylation. Int J Biol Macromol. 1991;13:281-5.
    • (1991) Int. J. Biol. Macromol. , vol.13 , pp. 281-285
    • Wang, W.1    Bo, S.2    Li, S.3    Qin, W.4
  • 21
    • 0037436976 scopus 로고    scopus 로고
    • Galactosylated low molecular weight chitosan as DNA carrier for hepatocytetargeting
    • Gao S, Chen J, Xu X, Zhi D, Yang Y, Hua Z et al. Galactosylated low molecular weight chitosan as DNA carrier for hepatocytetargeting. Int J Pharm. 2003;255:57-68.
    • (2003) Int. J. Pharm. , vol.255 , pp. 57-68
    • Gao, S.1    Chen, J.2    Xu, X.3    Zhi, D.4    Yang, Y.5    Hua, Z.6
  • 22
    • 0346094226 scopus 로고    scopus 로고
    • Low molecular weight chitosan nanoparticles as new carriers for nasal vaccine delivery in mice
    • Vila A, Sanchez A, Janes K, Behrens I, Kissel T, Vila JL et al. Low molecular weight chitosan nanoparticles as new carriers for nasal vaccine delivery in mice. Eur J Pharm Biopharm. 2004;57:123-31.
    • (2004) Eur. J. Pharm. Biopharm. , vol.57 , pp. 123-131
    • Vila, A.1    Sanchez, A.2    Janes, K.3    Behrens, I.4    Kissel, T.5    Vila, J.L.6
  • 23
    • 0035147521 scopus 로고    scopus 로고
    • Assessment of the antitumour activity of targeted immunospecific albumin microspheres loaded with cisplatin and 5-fluorouracil: Toxicity against a rodent ovarian carcinoma in vitro
    • Truter EJ, Santos AS, Els WJ. Assessment of the antitumour activity of targeted immunospecific albumin microspheres loaded with cisplatin and 5-fluorouracil: toxicity against a rodent ovarian carcinoma in vitro. Cell Biol Int. 2001;25:51-9.
    • (2001) Cell. Biol. Int. , vol.25 , pp. 51-59
    • Truter, E.J.1    Santos, A.S.2    Els, W.J.3
  • 26
    • 2942603261 scopus 로고    scopus 로고
    • Structural and functional aspects of liver sinusoidal endothelial cell fenestrae: A review
    • Braet F, Wisse E. Structural and functional aspects of liver sinusoidal endothelial cell fenestrae: a review. Comp Hepatol. 2002;1:1-17.
    • (2002) Comp. Hepatol. , vol.1 , pp. 1-17
    • Braet, F.1    Wisse, E.2
  • 27
    • 34548424564 scopus 로고    scopus 로고
    • Receptor-mediated gene delivery using chemically modified chitosan
    • DOI 10.1088/1748-6041/2/3/S02, PII S1748604107496693, S02
    • Kim TH, Jiang HL, Nah JW, Cho MH, Akaike T, Cho CS. Receptor-mediated gene delivery using chemically modified chitosan. Biomed Mater. 2007;2: S95-100. (Pubitemid 47354097)
    • (2007) Biomedical Materials , vol.2 , Issue.3
    • Kim, T.H.1    Jiang, H.L.2    Nah, J.W.3    Cho, M.H.4    Akaike, T.5    Cho, C.S.6
  • 29
    • 7444268954 scopus 로고    scopus 로고
    • Recent advances on chitosan-based micro-and nanoparticles in drug delivery
    • Agnihotri SA, Mallikarjuna NN, Aminabhavi TM. Recent advances on chitosan-based micro-and nanoparticles in drug delivery. J Control Release. 2004;100:5-28.
    • (2004) J. Control Release , vol.100 , pp. 5-28
    • Agnihotri, S.A.1    Mallikarjuna, N.N.2    Aminabhavi, T.M.3
  • 30
    • 0036132972 scopus 로고    scopus 로고
    • Free radical degradation of chitosan with potassium persulfate
    • Hsu SC, Don TM, Chiua WY. Free radical degradation of chitosan with potassium persulfate. Polym Degrad Stab. 2002;75:73-83.
    • (2002) Polym. Degrad Stab. , vol.75 , pp. 73-83
    • Hsu, S.C.1    Don, T.M.2    Chiua, W.Y.3
  • 31
    • 1242314681 scopus 로고    scopus 로고
    • Uptake and cytotoxicity of chitosan molecules and nanoparticles: Effects of molecular weight and degree of deacetylation
    • Huang M, Khor E, Lim L. Uptake and cytotoxicity of chitosan molecules and nanoparticles: effects of molecular weight and degree of deacetylation. Pharm Res. 2004;21:344-53.
    • (2004) Pharm. Res. , vol.21 , pp. 344-353
    • Huang, M.1    Khor, E.2    Lim, L.3
  • 32
    • 3543051289 scopus 로고    scopus 로고
    • The depolymerization of chitosan: Effects on physicochemical and biological properties
    • Mao S, Shuai X, Unger F. The depolymerization of chitosan: effects on physicochemical and biological properties. Int J Pharm. 2004;281:45-54.
    • (2004) Int. J. Pharm. , vol.281 , pp. 45-54
    • Mao, S.1    Shuai, X.2    Unger, F.3
  • 34
    • 0025200076 scopus 로고
    • Use of maleimide-thiol coupling chemistry for efficient synthesis of digonucleotide-enzyme conjugate hybridisation probes
    • Ghosh SS, Kao PM, McCue AW, Chappelle HL. Use of maleimide-thiol coupling chemistry for efficient synthesis of digonucleotide-enzyme conjugate hybridisation probes. Bioconjug Chem. 1990;1:71-6.
    • (1990) Bioconjug Chem. , vol.1 , pp. 71-76
    • Ghosh, S.S.1    Kao, P.M.2    McCue, A.W.3    Chappelle, H.L.4
  • 35
    • 0036153895 scopus 로고    scopus 로고
    • Crosslinked chitosan microspheres for encapsulation of diclofenac sodium: Effect of crosslinking agent
    • Kumbar SG, Kulkarni AR, Aminabhavi TM. Crosslinked chitosan microspheres for encapsulation of diclofenac sodium: effect of crosslinking agent. J Microencapsulation. 2002;19:173-80.
    • (2002) J. Microencapsulation , vol.19 , pp. 173-180
    • Kumbar, S.G.1    Kulkarni, A.R.2    Aminabhavi, T.M.3
  • 36
    • 0035936972 scopus 로고    scopus 로고
    • Chitosan-DNA nanoparticles as gene carriers: Synthesis, characterization and transfection efficiency
    • Mao HQ, Roy K, Troung-Le VL, Janes KA, Lim KY, Wang Y et al. Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency. J Control Release. 2001;70:399-421.
    • (2001) J. Control Release , vol.70 , pp. 399-421
    • Mao, H.Q.1    Roy, K.2    Troung-Le, V.L.3    Janes, K.A.4    Lim, K.Y.5    Wang, Y.6
  • 37
    • 0032881548 scopus 로고    scopus 로고
    • Chitosan microspheres prepared by spray drying
    • He P, Davis SS, Illum L. Chitosan microspheres prepared by spray drying. Int J Pharm. 1999;187:53-65.
    • (1999) Int. J. Pharm. , vol.187 , pp. 53-65
    • He, P.1    Davis, S.S.2    Illum, L.3
  • 38
    • 0035816156 scopus 로고    scopus 로고
    • Tumour targeted delivery of encapsulated dextran-doxorubicin conjugate using chitosan nanoparticles as carrier
    • Mitra S, Gaur U, Ghosh PC, Maitra AN. Tumour targeted delivery of encapsulated dextran-doxorubicin conjugate using chitosan nanoparticles as carrier. J Control Release. 2001;74:317-23.
    • (2001) J. Control Release , vol.74 , pp. 317-323
    • Mitra, S.1    Gaur, U.2    Ghosh, P.C.3    Maitra, A.N.4
  • 39
    • 0033404225 scopus 로고    scopus 로고
    • Chitosan-gadopentetic acid complex nanoparticles for gadolinium neutron- capture therapy of cancer: Preparation by novel emulsion- droplet coalescence technique and characterization
    • Tokumitsu H, Ichikawa H, Fukumori Y. Chitosan-gadopentetic acid complex nanoparticles for gadolinium neutron-capture therapy of cancer: preparation by novel emulsion-droplet coalescence technique and characterization. Pharm Res. 1999;16:1830-5. (Pubitemid 30040698)
    • (1999) Pharmaceutical Research , vol.16 , Issue.12 , pp. 1830-1835
    • Tokumitsu, H.1    Ichikawa, H.2    Fukumori, Y.3
  • 40
    • 0037148687 scopus 로고    scopus 로고
    • Controlled drug release properties of ionically cross-linked chitosan beads: The influence of anion structure
    • Shu XZ, Zhu KJ. Controlled drug release properties of ionically cross-linked chitosan beads: the influence of anion structure. Int J Pharm. 2002;233:217-25.
    • (2002) Int. J. Pharm. , vol.233 , pp. 217-225
    • Shu, X.Z.1    Zhu, K.J.2
  • 41
    • 0037413407 scopus 로고    scopus 로고
    • Effect of molecular structure of chitosan on protein delivery properties of chitosan nanoparticles
    • Xu Y, Du Y. Effect of molecular structure of chitosan on protein delivery properties of chitosan nanoparticles. Int J Pharm. 2003;250:215-26.
    • (2003) Int. J. Pharm. , vol.250 , pp. 215-226
    • Xu, Y.1    Du, Y.2
  • 42
    • 0032114834 scopus 로고    scopus 로고
    • Physico-chemical characterization of chitosans varying in degree of acetylation
    • Berth G, Dautzenberg H, Peter MG. Physico-chemical characterization of chitosans varying in degree of acetylation. Carbohydr Polym. 1998;36:205-16.
    • (1998) Carbohydr Polym. , vol.36 , pp. 205-216
    • Berth, G.1    Dautzenberg, H.2    Peter, M.G.3
  • 43
    • 0026013604 scopus 로고
    • Studies on chitosan: 3. Evidence for the presence of random and block copolymer structures in partially N-acetylated chitosans
    • Aiba SI. Studies on chitosan: 3. Evidence for the presence of random and block copolymer structures in partially N-acetylated chitosans. Int J Bio Macromol. 1991;13:40-4.
    • (1991) Int. J. Bio. Macromol. , vol.13 , pp. 40-44
    • Aiba, S.I.1
  • 45
    • 23444441931 scopus 로고    scopus 로고
    • Modulation of surface charge, particle size and morphological properties of chitosan-TPP nanoparticles intended for gene delivery
    • Gan Q, Wang T, Cochrane C, McCarron P. Modulation of surface charge, particle size and morphological properties of chitosan-TPP nanoparticles intended for gene delivery. Colloids Surf B Biointerfaces. 2005;44:65-73.
    • (2005) Colloids Surf B. Biointerfaces , vol.44 , pp. 65-73
    • Gan, Q.1    Wang, T.2    Cochrane, C.3    McCarron, P.4
  • 46
    • 26244467518 scopus 로고    scopus 로고
    • In vitro effects of chitosan nanoparticles on proliferation of human gastric carcinoma cell line MGC803 cells
    • Qi LF, Xu ZR, Li Y, Jiang X, Han XY. In vitro effects of chitosan nanoparticles on proliferation of human gastric carcinoma cell line MGC803 cells. World J Gastroenterol. 2005;11:5136-41.
    • (2005) World J. Gastroenterol. , vol.11 , pp. 5136-5141
    • Qi, L.F.1    Xu, Z.R.2    Li, Y.3    Jiang, X.4    Han, X.Y.5
  • 48
    • 0035838448 scopus 로고    scopus 로고
    • Investigation on a novel corecoated microspheres protein delivery system
    • Zhou SB, Deng XM, Li XH. Investigation on a novel corecoated microspheres protein delivery system. J Control Release. 2001;75:27-36.
    • (2001) J. Control Release , vol.75 , pp. 27-36
    • Zhou, S.B.1    Deng, X.M.2    Li, X.H.3
  • 49
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods. 1983;65:55-63.
    • (1983) J. Immunol. Methods , vol.65 , pp. 55-63
    • Mosmann, T.1


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