Lactosaminated and intact N-succinyl-chitosans as drug carriers in liver metastasis

International Journal of Pharmaceutics

Volumn 226, Issue 1-2, 2001, Pages 93-106

  Kato, Yoshinori ^a   Onishi, Hiraku ^a   Machida, Yoshiharu ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

Antitumor effect; Biodisposition; Lactosaminated N succinyl chitosan; M5076 liver metastasis; Mitomycin C; N Succinyl chitosan

Indexed keywords

CHITOSAN DERIVATIVE; DRUG CARRIER; MITOMYCIN; MITOMYCIN DERIVATIVE; N SUCCINYLCHITOSAN DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; AREA UNDER THE CURVE; ARTICLE; CANCER STAGING; CELL STRAIN; CONJUGATE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BLOOD LEVEL; DRUG CONJUGATION; DRUG DISTRIBUTION; DRUG EFFECT; DRUG EFFICACY; DRUG ELIMINATION; DRUG LIVER LEVEL; DRUG RETENTION; DRUG URINE LEVEL; FLUORESCENCE; INOCULATION; LIVER METASTASIS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RETICULOSARCOMA; SYSTEMIC CIRCULATION; URINARY EXCRETION;

ANIMALS; AREA UNDER CURVE; CHITIN; CHITOSAN; DRUG CARRIERS; INJECTIONS, INTRAVENOUS; LACTOSE; LIVER NEOPLASMS, EXPERIMENTAL; MALE; MICE; MICE, INBRED C57BL; MITOMYCIN; NEOPLASM METASTASIS; TISSUE DISTRIBUTION;

EID: 0035845738     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5173(01)00777-3     Document Type: Article

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