Discovery of small molecule inhibitors of xyloglucan endotransglucosylase (XET) activity by high-throughput screening

Phytochemistry

Volumn 117, Issue , 2015, Pages 220-236

  Chormova, Dimitra ^a   Franková, Lenka ^a   Defries, Andrew ^b,c   Cutler, Sean R ^b   Fry, Stephen C ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Backman Defries   (United States)

Author keywords

Anthraquinones; Cell wall; Chemical genetics; Dot blot assay; Flavonoids; Riboflavin; Singlet oxygen; Sulphydryl reagents; Tannins; Xyloglucan endotransglucosylase (XET)

Indexed keywords

PETROSELINUM; ZEA;

ENZYME INHIBITOR; GLUCAN; GLYCOSYLTRANSFERASE; MOLECULAR LIBRARY; RIBOFLAVIN; TANNIN DERIVATIVE; XENOBIOTIC AGENT; XYLAN; XYLOGLUCAN; XYLOGLUCAN - XYLOGLUCOSYLTRANSFERASE;

ANTAGONISTS AND INHIBITORS; CELL CULTURE TECHNIQUE; CELL WALL; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; ENZYMOLOGY; HIGH THROUGHPUT SCREENING; IC50; LIGHT; MAIZE; METABOLISM; MOLECULAR LIBRARY; PETROSELINUM; PHARMACOLOGY; PROCEDURES; ROSE;

CELL CULTURE TECHNIQUES; CELL WALL; ENZYME INHIBITORS; GLUCANS; GLYCOSYLTRANSFERASES; HIGH-THROUGHPUT SCREENING ASSAYS; INHIBITORY CONCENTRATION 50; LIGHT; PETROSELINUM; RIBOFLAVIN; ROSA; SMALL MOLECULE LIBRARIES; TANNINS; XENOBIOTICS; XYLANS; ZEA MAYS;

EID: 84934949259     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phytochem.2015.06.016     Document Type: Article

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