Anticancer properties of low molecular weight oat beta-glucan - An in vitro study

International Journal of Biological Macromolecules

Volumn 80, Issue , 2015, Pages 23-28

  Choromanska, Anna ^a   Kulbacka, Julita ^a   Rembialkowska, Nina ^a   Pilat, Justyna ^a   Oledzki, Remigiusz ^b   Harasym, Joanna ^b   Saczko, Jolanta ^a  

^a WROCLAW MEDICAL UNIVERSITY   (Poland)

^b WROCLAW UNIVERSITY OF ECONOMICS   (Poland)

Author keywords

Melanoma; Oat beta glucan; Skin cancer

Indexed keywords

BETA GLUCAN; CASPASE 12; LOW MOLECULAR WEIGHT OAT BETA GLUCAN; POLYSACCHARIDE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; CASP12 PROTEIN, HUMAN;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG FORMULATION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; INCUBATION TIME; MACROPHAGE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; VISCOSITY; ADULT; ANIMAL; AVENA; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; DRUG SCREENING; MALE; MELANOMA; METABOLISM; MOLECULAR WEIGHT; PATHOLOGY; PHYSIOLOGY; SECONDARY; SKIN NEOPLASMS; TUMOR CELL LINE;

AVENA; FUNGI; MURINAE;

ADULT; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; AVENA; BETA-GLUCANS; CASPASE 12; CELL LINE, TUMOR; CELL SURVIVAL; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MACROPHAGES; MALE; MELANOMA; MICE; MOLECULAR WEIGHT; SKIN NEOPLASMS;

EID: 84934948712     PISSN: 01418130     EISSN: 18790003     Source Type: Journal    
DOI: 10.1016/j.ijbiomac.2015.05.035     Document Type: Article

References (39)

1. Stošić-Grujičić S., Mijatović S., Maksimović-Ivanić D. An evidence-based perspective of Coriolus Versicolor (Multicolored Polypore Mushroom) for cancer patients. Evidence-based Anticancer Materia Medica 2011, 265-302. Springer Dordrecht Heidelberg, London/New York. C.S. William (Ed.).
2. Choromanska A., Saczko J., Kulbacka J., Skolucka N., Majkowski M. The potential role of photodynamic therapy in the treatment of malignant melanoma - an in vitro study. Adv. Clin. Exp. Med. 2012, 21:179-186.
3. Chi-Fung Chan G., Keung Chan W., Man-Yuen Sze D. The effects of beta-glucan on human immune and cancer cells. J. Hematol. Oncol. 2009, 25. 10.1186/1756-8722-2-25.
4. Borchers A.T., Keen C.L., Gershwin M.E. Mushrooms, tumors, and immunity: an update. Exp. Biol. Med. (Maywood) 2004, 229:393-406.
5. Chang R. Bioactive polysaccharides from traditional Chinese medicine herbs as anticancer adjuvants. J. Altern. Complement. Med. 2002, 8:559-565.
6. Bohn J.A., BeMiller J.N. (1-3)-b-d-Glucans as biological response modifiers: a review of structure-functional activity relationships. Carbohydr. Polym. 1995, 28:3-14.
7. Hong J.H., Jung H.K. Antioxidant and antitumor activities of beta-glucan rich exopolysaccharides with different molecular weight from Paenibacillus polymyxa JB115. J. Korean Soc. Appl. Biol. Chem. 2014, 57:105-112.
8. Jung H.K., Park S.C., Park B.K., Hong J.H. Physiological activities of a b-glucan produced by Panebacillus polymyxa. Biotechnol. Lett. 2008, 30:1545-1551.
9. Kimura Y., Sumiyoshi M., Suzuki T., Sakanaka M. Antitumor and antimetastatic activity of a novel water-soluble low molecular weight, beta-1,3-d-glucan (branch beta-1,6) isolated from Aureobasidium pullulans 1A1 strain black yeast. Anticancer Res. 2006, 26:4131-4142.
10. Cheung N.K., Modak S., Vickers A., Knuckles B. Orally administered beta-glucans enhance anti-tumor effects of monoclonal antibodies. Cancer Immunol. Immunother. 2002, 51:557-564.
11. Fang J., Wang Y., Lv X., Shen X., Ni X., Ding K. Structure of a beta-glucan from Grifola frondosa and its antitumor effect by activating Dectin-1/Syk/NF-κB signaling. Glycoconj. J. 2012, 29:365-377.
12. Lee S.Y., Lee Y.G., Byeon S.E., Han S., Choi S.S., Kim A.R., Lee J., Lee S.J., Hong S., Cho J.Y. Mitogen activated protein kinases are prime signaling enzymes in nitric oxide production induced by soluble beta-glucan from Sparassis crispa. Arch. Pharm. Res. 2010, 33:1753-1760.
13. Brown G.D., Taylor P.R., Reid D.M., Willment J.A., Williams D.L., Martinez-Pomares L., Wong S.Y., Gordon S. Dectin-1 is a major beta-glucan receptor on macrophages. J. Exp. Med. 2002, 196:407-412.
14. Kankkunen P., Teirilä L., Rintahaka J., Alenius H., Wolff H., Matikainen S. (1,3)-Beta-glucans activate both dectin-1 and NLRP3 inflammasome in human macrophages. J. Immunol. 2010, 184:6335-6342.
15. Taylor P.R., Brown G.D., Reid D.M., Willment J.A., Martinez-Pomares L., Gordon S., Wong S.Y. The beta-glucan receptor, dectin-1, is predominantly expressed on the surface of cells of the monocyte/macrophage and neutrophil lineages. J. Immunol. 2002, 169:3876-3882.
16. Ross G.D., Cain J.A., Lachmann P.J. Membrane complement receptor type three (CR3) has lectin-like properties analogous to bovine conglutinin as functions as a receptor for zymosan and rabbit erythrocytes as well as a receptor for iC3b. J. Immunol. 1985, 134:3307.
17. Zimmerman J.W., Lindermuth J., Fish P.A., Palace G.P., Stevenson T.T., DeMong D.E. A novel carbohydrate-glycosphingolipid interaction between a β-(1-3)-glucan immunomodulator, PGG-glucan, and lactosylceramide of human leukocytes. J. Biol. Chem. 1998, 273:22014.
18. Zhang M., Cui S.W., Cheung P.C.K., Wang Q. Antitumor polysaccharides from mushrooms: a review on their isolation process, structural characteristics and antitumor activity. Trends Food Sci. Technol. 2007, 18:4-19.
19. Hong F., Yan J., Baran J.T., Allendorf D.J., Hansen R.D., Ostroff G.R., Xing P.X., Cheung N.K., Ross G.D. Mechanism by which orally administered beta-1,3-glucans enhance the tumoricidal activity of antitumor monoclonal antibodies in murine tumor models. J. Immunol. 2004, 173:797-806.
20. Schorey J.S., Lawrence C. The pattern recognition receptor Dectin-1: from fungi to mycobacteria. Curr. Drug Targets 2008, 9:123-129.
21. Goodridge H.S., Simmons R.M., Underhill D.M. Dectin-1 stimulation by Candida albicans yeast or zymosan triggers NFAT activation in macrophages and dendritic cells. J. Immunol. 2007, 178:3107-3115.
22. Gross O., Gewies A., Finger K., Schafer M., Sparwasser T., Peschel C., Forster I., Ruland J. Card9 controls a non-TLR signaling pathway for innate anti-fungal immunity. Nature 2006, 7103:651-656.
23. Lazaridoua A., Papoutsib Z., Biliaderisa G.C., Moutsatsou P. Effect of oat and barley β-glucans on inhibition of cytokine-induced adhesion molecule expression in human aortic endothelial cells: molecular structure-function relations. Carbohydr. Polym. 2011, 84:153-161.
24. Sato T., Iwabuchi K., Nagaoka I., Adachi Y., Ohno N., Tamura H., Seyama K., Fukuchi Y., Nakayama H., Yoshizaki F., Takamori K., Ogawa H. Induction of human neutrophil chemotaxis by Candida albicans-derived beta-1,6-long glycoside side-chain-branched beta-glucan. J. Leukoc. Biol. 2006, 80:204-211.
25. Chan W.K., Law H.K., Lin Z.B., Lau Y.L., Chan G.C. Response of human dendritic cells to different immunomodulatory polysaccharides derived from mushroom and barley. Int. Immunol. 2007, 19:891-899.
26. Sandula S., Kogan G., Kacurakoca M., Machova E. Microbial beta-(1,3)-d-glucans, their preparation, physicochemical characterization and immonomodulatory activity. Carbohydr. Polym. 1999, 38:247-253.
27. Rahar S., Swami G., Nagpal N., Nagpal M.A., Singh G.S. Preparation, characterization, and biological properties of β-glucans. J. Adv. Pharm. Technol. Res. 2011, 2(2):94-103.
28. Daou C., Zhang H. Oat beta-glucan: its role in health promotion and prevention of diseases. Comp. Rev. Food Sci. Food Saf. 2012, 11:355-365.
29. Harasym J., Suchecka D., Gromadzka-Ostrowska J. Effect of raw material size reduction by freeze-milling on beta-glucan recovery process from oat bran. J. Cereal Sci. 2015, 61:119-125. 10.1016/j.jcs.2014.10.010.
30. Cheung N.K.V., Modak S., Vickers A., Knuckles B. Orally administered beta-glucans enhance anti-tumor effects of monoclonal antibodies. Cancer Immunol. Immunother. 2002, 51:557-564.
31. Huang Q., Zhang L., Cheung P.C.K., Tan X. Evaluation of sulfated α-glucans from Poria cocos mycelia as potential antitumor agent. Carbohydr. Polym. 2006, 64:337-344.
32. Hong J.H., Jung H.K. Antioxidant and antitumor activities of β-glucan-rich exopolysaccharides with different molecular weight from Paenibacillus polymyxa JB115. J. Korean Soc. Appl. Biol. Chem. 2014, 57(1):105-112.
33. Liang T.Z., Wang S.L. Recent advances in exopolysaccharides from Paenibacillus spp.: production, isolation, structure, and bioactivities. Mar. Drugs 2015, 13:1847-1863.
34. Malinovska L., Kroschwald S., Munder M.C., Richter D., Alberti S. Molecular chaperones and stress-inducible protein-sorting factors coordinate the spatiotemporal distribution of protein aggregates. Mol. Biol. Cell 2012, 23:3041-3056.
35. Yoon T.J., Kim T.J., Lee H., Shin K.S., Yun Y.P., Moon W.K., Kim D.W., Lee K.H. Anti-tumor metastatic activity of beta-glucan purified from mutated Saccharomyces cerevisiae. Int. Immunopharmacol. 2008, 8(January (1)):36-42.
36. Castano A.P., Demidova T.N., Hamblin M.R. Mechanisms in photodynamic therapy: Part two - Photosensitizers, photochemistry and cellular localization. Photodiagnosis Photodyn. Ther. 2004, 1:279-293.
37. Choromanska A., Kulbacka J., Chwiłkowska A., Skołucka N., Gamian A., Saczko J. Can photodynamic therapy be an alternative method in melanoma treatment?. Treatment of Metastatic Melanoma 2012, 271-294. InTech. R. Moorton (Ed.).
38. Lin X., Jun Y., Jiao C.-J., Chen Q., Liu Z.-L., Wang R. Structure determination, apoptosis induction, and telomerase inhibition of CFP-2, a novel lichenin from Cladonia furcata. Biochim. Biophys. Acta 2003, 1622:99-108.
39. Parzonko A., Makarewicz-Wujec M., Jaszewska E., Harasym J., Kozłowska-Wojciechowska M. Pro-apoptotic properties of (1,3)(1,4)-β-d-glucan from Avena sativa on human melanoma HTB 140 cells in vitro. Int. J. Biol. Macromol. 2015, 72:757-763.