Host lysozyme-mediated lysis of Lactococcus lactis facilitates delivery of colitis-attenuating superoxide dismutase to inflamed colons

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 25, 2015, Pages 7803-7808

  Ballal, Sonia A ^a,b   Veiga, Patrick ^b,c   Fenn, Kathrin ^b   Michaud, Monia ^b   Kim, Jason H ^b   Gallini, Carey Ann ^b   Glickman, Jonathan N ^d,e   Quéré, Gaëlle ^c   Garault, Peggy ^c   Béal, Chloé ^c   Derrien, Muriel ^c   Courtin, Pascal ^f   Kulakauskas, Saulius ^f   Chapot Chartier, Marie Pierre ^f   Van Hylckama Vlieg, Johan ^c,i   Garrett, Wendy S ^b,d,g,h  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c DANONE RESEARCH   (France)

^d HARVARD MEDICAL SCHOOL   (United States)

^e MIRACA LIFE SCIENCES   (United States)

^f UMR1319 MICALIS   (France)

^g DANA FARBER CANCER INSTITUTE   (United States)

^h BROAD INSTITUTE OF MIT AND HARVARD   (United States)

ⁱ CHR HANSEN A S   (Denmark)

Author keywords

Colitis; Lactococcus lactis; Lysozyme; Oxidative stress; Probiotics

Indexed keywords

DEXTRAN SULFATE; LYSOZYME; OXYGEN; PROBIOTIC AGENT; RAG2 PROTEIN; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR T BET;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; COLITIS; CONTROLLED STUDY; FERMENTED PRODUCT; GENE IDENTIFICATION; GENE INACTIVATION; GENETIC ANALYSIS; INTESTINE MUCOSA; LACTOCOCCUS LACTIS; LACTOCOCCUS LACTIS I 1631; LYSIS; MILK; MOUSE; NONHUMAN; OXIDATIVE STRESS; PATHOLOGY; PRIORITY JOURNAL; TISSUE INJURY; ANIMAL; ENZYMOLOGY; METABOLISM; MICROBIOLOGY;

LACTOCOCCUS LACTIS; MUS;

ANIMALS; COLITIS; INTESTINAL MUCOSA; LACTOCOCCUS LACTIS; MICE; MURAMIDASE; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

EID: 84934933158     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1501897112     Document Type: Article

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