A Helix-Loop-Helix Peptide at the Upper Lip of the Active Site Cleft of Lysozyme Confers Potent Antimicrobial Activity with Membrane Permeabilization Action

Journal of Biological Chemistry

Volumn 276, Issue 47, 2001, Pages 43767-43774

  Ibrahim, Hisham R ^a   Thomas, Ursula ^b   Pellegrini, Antonio ^b  

^a KAGOSHIMA UNIVERSITY   (Japan)

^b UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; DNA; ELECTROCHEMISTRY; STRAIN;

LYSOZYMES;

BIOCHEMISTRY;

CLOSTRIPAIN; DNA BINDING PROTEIN; EGG WHITE; HELIX LOOP HELIX PROTEIN; LYSOZYME; ANTIINFECTIVE AGENT; MEMBRANE LIPID; PEPTIDE; TRYPTOPHAN;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANTIMICROBIAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CATALYSIS; CONTROLLED STUDY; DRUG POTENCY; ENZYME ACTIVE SITE; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; INFECTION; MEMBRANE PERMEABILITY; NONHUMAN; OUTER MEMBRANE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN SECONDARY STRUCTURE; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CELL MEMBRANE POTENTIAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; METABOLISM; MICROBIOLOGICAL EXAMINATION; MOLECULAR GENETICS; PHYSIOLOGY; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY; SPECTROFLUOROMETRY;

ANIMALIA; BACTERIA (MICROORGANISMS); CANDIDA; CANDIDA ALBICANS; FUNGI; GALLUS GALLUS; NEGIBACTERIA; POSIBACTERIA;

AMINO ACID SEQUENCE; ANIMALS; ANTI-BACTERIAL AGENTS; BINDING SITES; HELIX-LOOP-HELIX MOTIFS; MEMBRANE LIPIDS; MEMBRANE POTENTIALS; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MURAMIDASE; PEPTIDES; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; SPECTROMETRY, FLUORESCENCE; TRYPTOPHAN;

EID: 0035941271     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M106317200     Document Type: Article

References (51)

1. Schindler, M., Assaf, Y., Sharon, N., and Chipman, D. M. (1977) Biochemistry 16, 423-431
2. Hasselberger, F. X. (1978) in Uses of Enzymes and Immobilized Enzymes (Hasselberger, F. X., ed) pp. 128, Nelson-Hall Inc., Chicago
3. Osserman, E. F., Klockars, M., Halper, J., and Fischer, R. E. (1974) in Lysozyme (Osserman, E. F., Canfield, R. E., and Beychok, S., eds), Academic Press, New York
4. Kokoshis, P. L., Williams, D. L., Cook, J. A., and Di-Luzio, N. R. (1978) Science 199, 1340-1342
5. Thacore, H., and Willet, H. P. (1966) Am. Rev. Respir. Dis. 93, 786-790
6. Lemarbre, P., Rinehart, J. J., Kay, N. E., Vesella, R., and Jacobs, H. S. (1981) Blood 58, 994-999
7. Sava, G., Ceschia, V., and Zabucchi, G. (1988) Eur. J. Cancer Clin. Oncol. 24, 1737-1743
8. Posse, E., De Arcuri, B. F., and Morero, R. D. (1994) Biochim. Biophys. Acta 1193, 101-106
9. Banks, J. G., Board, R. G., and Sparks, N. H. (1986) Biotechnol. Appl. Biochem. 8, 103-147
10. Hughey, V. L., and Johnson, E. A. (1987) Appl. Environ. Microbiol. 53, 2165-2170
11. Ohno, N., and Morrison, D. C. (1989) J. Biol. Chem. 264, 4434-4441
12. Engstrom, A., Kadalayil, L., Sun, S. C., Samakovlis, C., Hultmark, D., and Faye, I. (1993) J. Mol. Biol. 232, 327-333
13. Hultmark, D., Steiner, H., Rasmuson, T., and Boman, H. G. (1980) Eur. J. Biochem. 106, 7-16
14. Bukharin, O. V., Usviatsov, B. I., Matiiash, I. N., Pastukhova, G. V., and Prianishnikova, L. I. (1976) Antibiotiki (Mosc.) 21,805-808
15. Coonrod, J. D. (1986) Semin. Respir. Infect. 1, 118-129
16. Kudinova, T. I. (1976) Antibiotiki (Mosc.) 21, 441-444
17. Jolles, J., and Jolles, P. (1984) Mol. Cell. Biochem. 63, 165-189
18. Laible, N. J., and Germaine, G. R. (1985) Infect. Immun. 48, 720-728
19. Ibrahim, H. R. (1998) Nahrung 42, 187-193
20. Ibrahim, H. R., Higashiguchi, S., Juneja, L. R., Kim, M., and Yamamoto, T. (1996) J. Agric. Food Chem. 44, 1416-1423
21. Ibrahim, H. R., Higashiguchi, S., Koketsu, M., Juneja, L. R., Kim, M., Yamamoto, T., Sugimoto, Y., and Aoki, T. (1996) J. Agric. Food Chem. 44, 3799-3806
22. Ibrahim, H. R., Higashiguchi, S., Sugimoto, Y., and Aoki, T. (1997) J. Agric. Food Chem. 45, 89-94
23. Tomizawa, H., Yamada, H., Ueda, T., and Imoto, T. (1994) Biochemistry 33, 8770-8774
24. Pellegrini, A., Thomas, U., Bramaz, N., LKlauser, S., Hunziker, P., and Fellenberg, R. V. (1997) J. Appl. Microbiol. 82, 372-378
25. Engelman, D. M., and Steitz, T. A. (1981) Cell 23, 411-422
26. Srisailam, S., Arunkumar, A. I., Wang, W., Yu, C., and Chen, H. M. (2000) Biochim. Biophys. Acta 15, 1-2
27. Boman, H. G., Faye, I., Gudmundsson, G. H., Lee, J. Y., and Lidholm, D. A. (1991) Eur. J. Biochem. 201, 23-31
28. Hung, S. C., Wang, W., Chan, S. I., and Chen, H. M. (1999) Biophys. J. 77, 3120-3133
29. Kim, Y., Valentine, K., Opella, S. J., Schendel, S. L., and Cramer, W. A. (1998) Protein Sci. 7, 342-348
30. Lindeberg, M., Zakharov, S. D., and Cramer, W. A. (2000) J. Mol. Biol. 295, 679-692
31. Song, H. Y., Cohen, F. S., and Cramer, W. A. (1991) J. Bacteriol. 173, 2927-2934
32. Viitanen, P., Newman, M. J., Foster, D. L., Wilson, T. H., and Kaback, R. (1986) Methods Enzymol. 125, 429-452
33. Lehrer, R. I., Barton, A., and Ganz, T. (1988) Immunol. Methods 108, 153-158
34. Ibrahim, H. R., Sugimoto, Y., and Aoki, T. (2000) Biochim. Biophys. Acta 1523, 196-205
35. Ibrahim, H. R., Yamada, M., Matsushita, K., Kobayashi, K., and Kato, A. (1994) J. Biol. Chem. 269, 5059-5063
36. Post, C. B., Brooks, B. R., Karplus, M., Dobson, C. M., Artymiuk, P. J., Cheetham, J. C., and Phillips, D. C. (1986) J. Mol. Biol. 190, 455-479
37. Chapman, E. R., and Davis, A. F. (1998) J. Biol. Chem. 273, 13995-14001
38. Leive, L. (1974) Ann. N. Y. Acad. Sci. 235, 109-129
39. Andreu, D., and Merrifield, R. B. (1985) Biochemistry 24, 1683-1688
40. Chen, H. C., Brown, J. H., Morell, J. L., and Huang, C. M. (1988) FEBS Lett. 236, 462-466
41. Song, H., Inaka, K., Maenaka, K., and Matsushima, M. (1994) J. Mol. Biol. 244, 522-540
42. Lee-Huang, S., Huang, P., Sun, Y., Kung, H. F., Blithe, D. L., and Chen, H. C. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 2678-2681
43. Wang, W., Smith, D. K., and Chen, H. M. (1999) Biochim. Biophys. Acta 1473, 418-430
44. Hristova, K., Selsted-Michael, E., and White, S. H. (1996) Biochemistry 35, 11888-11894
45. Kagan, B. L., Selsted, M. E., Ganz, T., and Lehrer, R. I. (1990) Proc. Natl. Acad. Sci. U. S. A. 87, 210-214
46. Wimley, W. C., Selsted, M. E., and White, S. H. A. (1994) Protein Sci. 3, 1362-1373
47. Ridder, A. N. J. A. (2000) Biochemistry 39, 6521-6528
48. Kovacs, F. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 7910-7915
49. Cross, T. A. (1999) Nat. Struct. Biol. 6, 610-611
50. White, S. H., Wimley, W. C., and Selsted, M. E. (1995) Curr. Opin. Struct. Biol. 5, 521-527
51. Shai, Y. (1995) Trends Biochem. Sci. 20, 460-464