Deletion of P58IPK, the cellular inhibitor of the protein kinases PKR and PERK, causes bone changes and joint degeneration in mice

Frontiers in Endocrinology

Volumn 5, Issue OCT, 2014, Pages

  Gilbert, Sophie J ^a   Meakin, Lee B ^b   Bonnet, Cleo S ^a   Nowell, Mari A ^c   Ladiges, Warren C ^d   Morton, John ^d   Duance, Victor C ^a   Mason, Deborah J ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c CARDIFF UNIVERSITY   (United Kingdom)

^d UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Articular cartilage; Bone; Osteoarthritis; P58IPK; PERK; PKR

Indexed keywords

CYTOKINE; ENDOPLASMIC RETICULUM STRESS INDUCIBLE PROTEIN; PROTEIN KINASE; PROTEIN KINASE LIKE ENDOPLASMIC RETICULUM KINASE; PROTEIN KINASE R; TOLONIUM CHLORIDE; UNCLASSIFIED DRUG;

ACHILLES TENDON; ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTICULAR CARTILAGE; BONE DENSITY; BONE LENGTH; BONE RADIOGRAPHY; CALCIFICATION; CARTILAGE DEGENERATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; FEMALE; FEMUR CONDYLE; FEMUR EPIPHYSIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; JOINT CAPSULE; JOINT DEGENERATION; KNEE; MALE; MICRO-COMPUTED TOMOGRAPHY; MIDDLE AGED; MOUSE; NONHUMAN; OSTEOARTHRITIS; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SCORING SYSTEM; TIBIA EPIPHYSIS; VERY ELDERLY;

EID: 84934878152     PISSN: None     EISSN: 16642392     Source Type: Journal    
DOI: 10.3389/fendo.2014.00174     Document Type: Article

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