Trans-spliced Cas9 allows cleavage of HBB and CCR5 genes in human cells using compact expression cassettes

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Fine, Eli J ^a   Appleton, Caleb M ^a   White, Douglas E ^a   Brown, Matthew T ^a   Deshmukh, Harshavardhan ^a   Kemp, Melissa L ^a   Bao, Gang ^a  

^a Emory University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE RECEPTOR CCR5; CRISPR ASSOCIATED PROTEIN; ENDONUCLEASE; GUIDE RNA; HEMOGLOBIN BETA CHAIN;

AMINO ACID SEQUENCE; CELL LINE; CHEMISTRY; DNA SEQUENCE; GENE VECTOR; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; STREPTOCOCCUS PYOGENES; TRANS SPLICING; WESTERN BLOTTING;

AMINO ACID SEQUENCE; BASE SEQUENCE; BETA-GLOBINS; BLOTTING, WESTERN; CELL LINE; CRISPR-ASSOCIATED PROTEINS; ENDONUCLEASES; GENETIC VECTORS; HUMANS; MOLECULAR SEQUENCE DATA; RECEPTORS, CCR5; RNA, GUIDE; SEQUENCE ANALYSIS, DNA; STREPTOCOCCUS PYOGENES; TRANS-SPLICING;

EID: 84934784068     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep10777     Document Type: Article

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