-
1
-
-
2042437650
-
-
International Human Genome Sequencing Consortium
-
International Human Genome Sequencing Consortium. (2001) Nature 409, 860-921.
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
-
2
-
-
0035895505
-
-
Venter, J.C., Adams, M.D., Myers, E.W., Li, P.W., Mural, R.J., Sutton, G.G., et al. (2001) Science 291, 1304-1351.
-
(2001)
Science
, vol.291
, pp. 1304-1351
-
-
Venter, J.C.1
Adams, M.D.2
Myers, E.W.3
Li, P.W.4
Mural, R.J.5
Sutton, G.G.6
-
3
-
-
0035100888
-
Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework
-
Biomarkers Definitions Working Group
-
Biomarkers Definitions Working Group. (2001) Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clin. Pharmacol. Ther. 69, 89-95.
-
(2001)
Clin. Pharmacol. Ther
, vol.69
, pp. 89-95
-
-
-
4
-
-
2342540427
-
Molecular profiling approaches for identifying novel biomarkers
-
Bailey, W.J. and Ulrich, R. (2004) Molecular profiling approaches for identifying novel biomarkers. Expert Opin. Drug Saf. 3, 137-151.
-
(2004)
Expert Opin. Drug Saf
, vol.3
, pp. 137-151
-
-
Bailey, W.J.1
Ulrich, R.2
-
5
-
-
0141788179
-
Toxicogenomics in drug development
-
Guerreiro, N., Staedtler, F., Grenet, O., Kehren, J., and Chibout, S.D. (2003) Toxicogenomics in drug development. Toxicol. Pathol. 31, 471-479.
-
(2003)
Toxicol. Pathol
, vol.31
, pp. 471-479
-
-
Guerreiro, N.1
Staedtler, F.2
Grenet, O.3
Kehren, J.4
Chibout, S.D.5
-
6
-
-
4544244613
-
Research issues and strategies for genomic and proteomic biomarker discovery and validation: A statistical perspective
-
Feng, Z., Prentice, R., and Srivastava, S. (2004) Research issues and strategies for genomic and proteomic biomarker discovery and validation: a statistical perspective. Pharmacogenomics 5, 709-719.
-
(2004)
Pharmacogenomics
, vol.5
, pp. 709-719
-
-
Feng, Z.1
Prentice, R.2
Srivastava, S.3
-
7
-
-
0035988620
-
The promise of biomarkers in cancer screening and detection
-
Negm, R.S., Verma, M., and Srivastava, S. (2002) The promise of biomarkers in cancer screening and detection. Trends Mol. Med. 8, 288-293.
-
(2002)
Trends Mol. Med
, vol.8
, pp. 288-293
-
-
Negm, R.S.1
Verma, M.2
Srivastava, S.3
-
8
-
-
2542439561
-
Identification and measurement of genomic biomarkers of nephrotoxicity
-
Goodsaid, F.M. (2004) Identification and measurement of genomic biomarkers of nephrotoxicity. J. Pharmacol. Toxicol. Methods 49, 183-186.
-
(2004)
J. Pharmacol. Toxicol. Methods
, vol.49
, pp. 183-186
-
-
Goodsaid, F.M.1
-
9
-
-
0038178864
-
Drug-induced renal failure: Update on new medications and unique mechanisms of nephrotoxicity
-
Perazella, M.A. (2003) Drug-induced renal failure: update on new medications and unique mechanisms of nephrotoxicity. Am. J. Med. Sci. 325, 349-362.
-
(2003)
Am. J. Med. Sci
, vol.325
, pp. 349-362
-
-
Perazella, M.A.1
-
10
-
-
0029885106
-
Comparison of chloroform-induced toxicity in the kidneys, liver, and nasal passages of male Osborne-Mendel and F-344 rats
-
Templin, M.V., Jamison, K.C., Wolf, D.C., Morgan, K.T., and Butterworth, B.E. (1996) Comparison of chloroform-induced toxicity in the kidneys, liver, and nasal passages of male Osborne-Mendel and F-344 rats. Cancer Lett. 104, 71-78.
-
(1996)
Cancer Lett
, vol.104
, pp. 71-78
-
-
Templin, M.V.1
Jamison, K.C.2
Wolf, D.C.3
Morgan, K.T.4
Butterworth, B.E.5
-
11
-
-
0041334075
-
Dose-dependent mercuric chloride tubular injury in rat kidney
-
Stacchiotti, A., Borsani, E., Rodella, L., Rezzani, R., Bianchi, R., and Lavazza, A. (2003) Dose-dependent mercuric chloride tubular injury in rat kidney. Ultrastruct. Pathol. 27, 253-259.
-
(2003)
Ultrastruct. Pathol
, vol.27
, pp. 253-259
-
-
Stacchiotti, A.1
Borsani, E.2
Rodella, L.3
Rezzani, R.4
Bianchi, R.5
Lavazza, A.6
-
12
-
-
6344282890
-
Mercuric chloride-induced alterations in stress protein distribution in rat kidney
-
Stacchiotti, A., Lavazza, A., Rezzani, R., Borsani, E., Rodella, L., and Bianchi, R. (2004) Mercuric chloride-induced alterations in stress protein distribution in rat kidney. Histol. Histopathol. 19, 1209-1218.
-
(2004)
Histol. Histopathol
, vol.19
, pp. 1209-1218
-
-
Stacchiotti, A.1
Lavazza, A.2
Rezzani, R.3
Borsani, E.4
Rodella, L.5
Bianchi, R.6
-
13
-
-
12144287350
-
Overview on the application of transcription profiling using selected nephrotoxicants for toxicology assessment
-
Kramer, J.A., Pettit, S.D., Amin, R.P., Bertram, T.A., Car, B., Cunningham, M., et al. (2004) Overview on the application of transcription profiling using selected nephrotoxicants for toxicology assessment. Environ. Health Perspect. 112, 460-464.
-
(2004)
Environ. Health Perspect
, vol.112
, pp. 460-464
-
-
Kramer, J.A.1
Pettit, S.D.2
Amin, R.P.3
Bertram, T.A.4
Car, B.5
Cunningham, M.6
-
14
-
-
0028266488
-
Short- and long-term treatment with indomethacin causes renal phospholipid alteration: A possible explanation for indomethacin nephrotoxicity
-
Fernandez-Tome, M.C., and Sterin-Speziale, N.B. (1994) Short- and long-term treatment with indomethacin causes renal phospholipid alteration: a possible explanation for indomethacin nephrotoxicity. Pharmacology 48, 341-348.
-
(1994)
Pharmacology
, vol.48
, pp. 341-348
-
-
Fernandez-Tome, M.C.1
Sterin-Speziale, N.B.2
-
15
-
-
0036314217
-
Kidney Injury Molecule-1 (KIM-1): A novel biomarker for human renal proximal tubule injury
-
Han, W.K., Bailly, V., Abichandani, R., Thadhani, R., and Bonventre, J.V. (2002) Kidney Injury Molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury. Kidney Int. 62, 237-244.
-
(2002)
Kidney Int
, vol.62
, pp. 237-244
-
-
Han, W.K.1
Bailly, V.2
Abichandani, R.3
Thadhani, R.4
Bonventre, J.V.5
-
16
-
-
3042570252
-
Discovery of protein biomarkers for renal diseases
-
Hewitt, S.M., Dear, J., and Star, R.A. (2004) Discovery of protein biomarkers for renal diseases. J. Am. Soc. Nephrol. 15, 1677-1689.
-
(2004)
J. Am. Soc. Nephrol
, vol.15
, pp. 1677-1689
-
-
Hewitt, S.M.1
Dear, J.2
Star, R.A.3
-
17
-
-
0029124742
-
Clusterin: Physiologic and pathophysiologic considerations
-
Rosenberg, M.E. and Silkensen, J. (1995) Clusterin: physiologic and pathophysiologic considerations. Int. J. Biochem. Cell. Biol. 27, 633-645.
-
(1995)
Int. J. Biochem. Cell. Biol
, vol.27
, pp. 633-645
-
-
Rosenberg, M.E.1
Silkensen, J.2
-
18
-
-
0035662208
-
Crescentic glomerulonephritis is diminished in fibrinogen-deficient mice
-
Drew, A.F., Tucker, H.L., Liu, H., Witte, D.P., Degen, J.L., and Tipping, P.G. (2001) Crescentic glomerulonephritis is diminished in fibrinogen-deficient mice. Am. J. Physiol. Renal Physiol. 281, F1157-1163.
-
(2001)
Am. J. Physiol. Renal Physiol
, vol.281
-
-
Drew, A.F.1
Tucker, H.L.2
Liu, H.3
Witte, D.P.4
Degen, J.L.5
Tipping, P.G.6
-
19
-
-
12144290763
-
Identification of putative gene based markers of renal toxicity
-
Amin, R.P., Vickers, A.E., Sistare, F., Thompson, K.L., Roman, R.J., Lawton, M., et al. (2004) Identification of putative gene based markers of renal toxicity. Environ. Health Perspect. 112, 465-479.
-
(2004)
Environ. Health Perspect
, vol.112
, pp. 465-479
-
-
Amin, R.P.1
Vickers, A.E.2
Sistare, F.3
Thompson, K.L.4
Roman, R.J.5
Lawton, M.6
-
20
-
-
4143131083
-
Biomarkers of congenital obstructive nephropathy: Past, present and future
-
Chevalier, R.L. (2004) Biomarkers of congenital obstructive nephropathy: past, present and future. J. Urol. 172, 852-857.
-
(2004)
J. Urol
, vol.172
, pp. 852-857
-
-
Chevalier, R.L.1
-
21
-
-
0032056008
-
The cyclosporine A-induced decrease in rat renal calbindin-D28kDa protein as a consequence of a decrease in its mRNA
-
Grenet, O., Varela, M.C., Staedtler, F., and Steiner, S. (1998) The cyclosporine A-induced decrease in rat renal calbindin-D28kDa protein as a consequence of a decrease in its mRNA. Biochem. Pharmacol. 55, 1131-1133.
-
(1998)
Biochem. Pharmacol
, vol.55
, pp. 1131-1133
-
-
Grenet, O.1
Varela, M.C.2
Staedtler, F.3
Steiner, S.4
-
22
-
-
0030904457
-
Clinical cardiotoxicity following anthracycline treatment for childhood cancer. the pediatric oncology group experience
-
Krischer, J.P., Epstein, S., Cuthbertson, D.D., Goorin, A.M., Epstein, M.L., and Lipshultz, S.E. (1997) Clinical cardiotoxicity following anthracycline treatment for childhood cancer. the pediatric oncology group experience. J. Clin. Oncol. 15, 1544-1552.
-
(1997)
J. Clin. Oncol
, vol.15
, pp. 1544-1552
-
-
Krischer, J.P.1
Epstein, S.2
Cuthbertson, D.D.3
Goorin, A.M.4
Epstein, M.L.5
Lipshultz, S.E.6
-
23
-
-
0036784463
-
Trastuzumab-associated cardiotoxicity
-
Keefe, D.L. (2002) Trastuzumab-associated cardiotoxicity. Cancer 95, 1592-1600.
-
(2002)
Cancer
, vol.95
, pp. 1592-1600
-
-
Keefe, D.L.1
-
24
-
-
0028001641
-
Cardiotoxicity as a doselimiting factor in a schedule of high dose bolus therapy with interleukin-2 and alpha-interferon. An unexpectedly frequent complication
-
Kruit, W.H., Punt, K.J., Goey, S.H., de Mulder, P.H., van Hoogenhuyze, D.C., Henzen-Logmans, S.C., and Stoter, G. (1994) Cardiotoxicity as a doselimiting factor in a schedule of high dose bolus therapy with interleukin-2 and alpha-interferon. An unexpectedly frequent complication. Cancer 74, 2850-2856.
-
(1994)
Cancer
, vol.74
, pp. 2850-2856
-
-
Kruit, W.H.1
Punt, K.J.2
Goey, S.H.3
de Mulder, P.H.4
van Hoogenhuyze, D.C.5
Henzen-Logmans, S.C.6
Stoter, G.7
-
26
-
-
14544268139
-
QT prolongation through hERG K(+) channel blockade: Current knowledge and strategies for the early prediction during drug development
-
Recanatini, M., Poluzzi, E., Masetti, M., Cavalli, A., and De Ponti, F. (2005) QT prolongation through hERG K(+) channel blockade: current knowledge and strategies for the early prediction during drug development. Med. Res. Rev. 25, 133-166.
-
(2005)
Med. Res. Rev
, vol.25
, pp. 133-166
-
-
Recanatini, M.1
Poluzzi, E.2
Masetti, M.3
Cavalli, A.4
De Ponti, F.5
-
27
-
-
10744232013
-
Serum troponins as biomarkers of drug-induced cardiac toxicity
-
Wallace, K.B., Hausner, E., Herman, E., Holt, G.D., MacGregor, J.T., Metz, A.L., et al. (2004) Serum troponins as biomarkers of drug-induced cardiac toxicity. Toxicol. Pathol. 32, 106-121.
-
(2004)
Toxicol. Pathol
, vol.32
, pp. 106-121
-
-
Wallace, K.B.1
Hausner, E.2
Herman, E.3
Holt, G.D.4
MacGregor, J.T.5
Metz, A.L.6
-
29
-
-
0035044440
-
Molecular and cellular mechanisms of cardiotoxicity
-
Kang, Y.J. (2001) Molecular and cellular mechanisms of cardiotoxicity. Environ. Health Perspect. 109 (Suppl 1), 27-34.
-
(2001)
Environ. Health Perspect
, vol.109
, Issue.SUPPL. 1
, pp. 27-34
-
-
Kang, Y.J.1
-
30
-
-
0026605560
-
Switches in cardiac muscle gene expresion as a result of pressure and volume overload
-
Schwartz, L., Boheler, K.R., De La Bastie, D., Lompre, A.M., and Mercadier, J-J. (1992) Switches in cardiac muscle gene expresion as a result of pressure and volume overload. Am. J. Physiol. 262, R364-369.
-
(1992)
Am. J. Physiol
, vol.262
-
-
Schwartz, L.1
Boheler, K.R.2
De La Bastie, D.3
Lompre, A.M.4
Mercadier, J.-J.5
-
31
-
-
0028926811
-
Load effects on gene expression during cardiac hypertrophy
-
Rozich, J.D., Barnes, M.A., Schmid, P.G., Zile, M.R., McDermott, P.J., and Cooper, G. (1995) Load effects on gene expression during cardiac hypertrophy. J. Mol. Cell. Cardiol. 27, 485-499.
-
(1995)
J. Mol. Cell. Cardiol
, vol.27
, pp. 485-499
-
-
Rozich, J.D.1
Barnes, M.A.2
Schmid, P.G.3
Zile, M.R.4
McDermott, P.J.5
Cooper, G.6
-
32
-
-
0026349336
-
Regulation of cardiac gene expression during myocardial growth and hypertrophy: Molecular studies of an adaptive physiologic response
-
Chien, K.R., Knowlton, K.U., Zhu, H., and Chien, S. (1991) Regulation of cardiac gene expression during myocardial growth and hypertrophy: molecular studies of an adaptive physiologic response. FASEB J. 5, 3037-3046.
-
(1991)
FASEB J
, vol.5
, pp. 3037-3046
-
-
Chien, K.R.1
Knowlton, K.U.2
Zhu, H.3
Chien, S.4
-
33
-
-
0028987620
-
Proto-oncogene expression in the isolated working rat heart: Combination of pressure and volume overload with norepinephrine
-
Kolbeck-Ruhmkorff, C. and Zimmer, H.G. (1995) Proto-oncogene expression in the isolated working rat heart: combination of pressure and volume overload with norepinephrine. J. Mol. Cell. Cardiol. 27, 501-511.
-
(1995)
J. Mol. Cell. Cardiol
, vol.27
, pp. 501-511
-
-
Kolbeck-Ruhmkorff, C.1
Zimmer, H.G.2
-
34
-
-
0041342015
-
Drug-induced hepatotoxicity
-
Lee, W.M. (2003) Drug-induced hepatotoxicity. N. Engl. J. Med. 349, 474-485.
-
(2003)
N. Engl. J. Med
, vol.349
, pp. 474-485
-
-
Lee, W.M.1
-
35
-
-
13844314221
-
The role of metabolic activation in drug-induced hepatotoxicity
-
Park, B.K., Kitteringham, N.R., Maggs, J.L., Pirmohamed, M., and Williams, D.P. (2005) The role of metabolic activation in drug-induced hepatotoxicity. Annu. Rev. Pharmacol. Toxicol. 45, 177-202.
-
(2005)
Annu. Rev. Pharmacol. Toxicol
, vol.45
, pp. 177-202
-
-
Park, B.K.1
Kitteringham, N.R.2
Maggs, J.L.3
Pirmohamed, M.4
Williams, D.P.5
-
36
-
-
0034685195
-
Serum aminotransferase concentration as evidence of hepatocellular damage
-
Kew, M.C. (2000) Serum aminotransferase concentration as evidence of hepatocellular damage. Lancet 355, 591-592.
-
(2000)
Lancet
, vol.355
, pp. 591-592
-
-
Kew, M.C.1
-
37
-
-
0037008076
-
Alanine aminotransferase levels: What's normal?
-
Kaplan, M.M. (2002) Alanine aminotransferase levels: what's normal? Ann. Intern. Med. 137, 49-51.
-
(2002)
Ann. Intern. Med
, vol.137
, pp. 49-51
-
-
Kaplan, M.M.1
-
38
-
-
1542437234
-
Expression pattern and regulation of heme oxygenase-1/heat shock protein 32 in human liver cells
-
Bauer, I., Rensing, H., Florax, A., Ulrich, C., Pistorius, G., Redl, H., and Bauer, M. (2003) Expression pattern and regulation of heme oxygenase-1/heat shock protein 32 in human liver cells. Shock 20, 116-122.
-
(2003)
Shock
, vol.20
, pp. 116-122
-
-
Bauer, I.1
Rensing, H.2
Florax, A.3
Ulrich, C.4
Pistorius, G.5
Redl, H.6
Bauer, M.7
-
39
-
-
0036847809
-
Lipopolysaccharide-binding protein and lipopolysaccharide receptor CD14 gene expression after thermal injury and its potential mechanism(s)
-
Fang, C.W., Yao, Y.M., Shi, Z.G., Yu, Y., Wu, Y., Lu, L.R., and Sheng, Z.Y. (2002) Lipopolysaccharide-binding protein and lipopolysaccharide receptor CD14 gene expression after thermal injury and its potential mechanism(s). J. Trauma 53, 957-967.
-
(2002)
J. Trauma
, vol.53
, pp. 957-967
-
-
Fang, C.W.1
Yao, Y.M.2
Shi, Z.G.3
Yu, Y.4
Wu, Y.5
Lu, L.R.6
Sheng, Z.Y.7
-
40
-
-
11144314814
-
Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron
-
Flo, T.H., Smith, K.D., Sato, S., Rodriguez, D.J., Holmes, M.A., Strong, R.K., et al. (2004) Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron. Nature 432, 917-921.
-
(2004)
Nature
, vol.432
, pp. 917-921
-
-
Flo, T.H.1
Smith, K.D.2
Sato, S.3
Rodriguez, D.J.4
Holmes, M.A.5
Strong, R.K.6
-
41
-
-
0036718796
-
Clinical proteomics: Translating benchside promise into bedside reality
-
Petricoin, E.F., Zoon, K.C., Kohn, E.C., Barrett, J.C., and Liotta, L.A. (2002) Clinical proteomics: translating benchside promise into bedside reality. Nat. Rev. Drug Discov. 1, 683-695.
-
(2002)
Nat. Rev. Drug Discov
, vol.1
, pp. 683-695
-
-
Petricoin, E.F.1
Zoon, K.C.2
Kohn, E.C.3
Barrett, J.C.4
Liotta, L.A.5
-
42
-
-
14844360651
-
The transcriptome in blood: Challenges and solutions for robust expression profiling
-
Fan, H. and Hegde, P.S. (2005) The transcriptome in blood: challenges and solutions for robust expression profiling. Curr. Mol. Med. 5, 3-10.
-
(2005)
Curr. Mol. Med
, vol.5
, pp. 3-10
-
-
Fan, H.1
Hegde, P.S.2
-
43
-
-
85069276612
-
-
® Expression Profiling Santa Clara, CA.
-
® Expression Profiling Santa Clara, CA.
-
-
-
|