메뉴 건너뛰기




Volumn 460, Issue , 2008, Pages 185-194

Toxicogenomics in biomarker discovery

Author keywords

Biomarker; Blood; Gene expression; Heart; Kidney; Molecular profiling; Toxicogenomics; Transcriptomics

Indexed keywords


EID: 84934443476     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-60327-48-9_9     Document Type: Article
Times cited : (14)

References (43)
  • 1
    • 2042437650 scopus 로고    scopus 로고
    • International Human Genome Sequencing Consortium
    • International Human Genome Sequencing Consortium. (2001) Nature 409, 860-921.
    • (2001) Nature , vol.409 , pp. 860-921
  • 3
    • 0035100888 scopus 로고    scopus 로고
    • Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework
    • Biomarkers Definitions Working Group
    • Biomarkers Definitions Working Group. (2001) Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clin. Pharmacol. Ther. 69, 89-95.
    • (2001) Clin. Pharmacol. Ther , vol.69 , pp. 89-95
  • 4
    • 2342540427 scopus 로고    scopus 로고
    • Molecular profiling approaches for identifying novel biomarkers
    • Bailey, W.J. and Ulrich, R. (2004) Molecular profiling approaches for identifying novel biomarkers. Expert Opin. Drug Saf. 3, 137-151.
    • (2004) Expert Opin. Drug Saf , vol.3 , pp. 137-151
    • Bailey, W.J.1    Ulrich, R.2
  • 6
    • 4544244613 scopus 로고    scopus 로고
    • Research issues and strategies for genomic and proteomic biomarker discovery and validation: A statistical perspective
    • Feng, Z., Prentice, R., and Srivastava, S. (2004) Research issues and strategies for genomic and proteomic biomarker discovery and validation: a statistical perspective. Pharmacogenomics 5, 709-719.
    • (2004) Pharmacogenomics , vol.5 , pp. 709-719
    • Feng, Z.1    Prentice, R.2    Srivastava, S.3
  • 7
    • 0035988620 scopus 로고    scopus 로고
    • The promise of biomarkers in cancer screening and detection
    • Negm, R.S., Verma, M., and Srivastava, S. (2002) The promise of biomarkers in cancer screening and detection. Trends Mol. Med. 8, 288-293.
    • (2002) Trends Mol. Med , vol.8 , pp. 288-293
    • Negm, R.S.1    Verma, M.2    Srivastava, S.3
  • 8
    • 2542439561 scopus 로고    scopus 로고
    • Identification and measurement of genomic biomarkers of nephrotoxicity
    • Goodsaid, F.M. (2004) Identification and measurement of genomic biomarkers of nephrotoxicity. J. Pharmacol. Toxicol. Methods 49, 183-186.
    • (2004) J. Pharmacol. Toxicol. Methods , vol.49 , pp. 183-186
    • Goodsaid, F.M.1
  • 9
    • 0038178864 scopus 로고    scopus 로고
    • Drug-induced renal failure: Update on new medications and unique mechanisms of nephrotoxicity
    • Perazella, M.A. (2003) Drug-induced renal failure: update on new medications and unique mechanisms of nephrotoxicity. Am. J. Med. Sci. 325, 349-362.
    • (2003) Am. J. Med. Sci , vol.325 , pp. 349-362
    • Perazella, M.A.1
  • 10
    • 0029885106 scopus 로고    scopus 로고
    • Comparison of chloroform-induced toxicity in the kidneys, liver, and nasal passages of male Osborne-Mendel and F-344 rats
    • Templin, M.V., Jamison, K.C., Wolf, D.C., Morgan, K.T., and Butterworth, B.E. (1996) Comparison of chloroform-induced toxicity in the kidneys, liver, and nasal passages of male Osborne-Mendel and F-344 rats. Cancer Lett. 104, 71-78.
    • (1996) Cancer Lett , vol.104 , pp. 71-78
    • Templin, M.V.1    Jamison, K.C.2    Wolf, D.C.3    Morgan, K.T.4    Butterworth, B.E.5
  • 13
    • 12144287350 scopus 로고    scopus 로고
    • Overview on the application of transcription profiling using selected nephrotoxicants for toxicology assessment
    • Kramer, J.A., Pettit, S.D., Amin, R.P., Bertram, T.A., Car, B., Cunningham, M., et al. (2004) Overview on the application of transcription profiling using selected nephrotoxicants for toxicology assessment. Environ. Health Perspect. 112, 460-464.
    • (2004) Environ. Health Perspect , vol.112 , pp. 460-464
    • Kramer, J.A.1    Pettit, S.D.2    Amin, R.P.3    Bertram, T.A.4    Car, B.5    Cunningham, M.6
  • 14
    • 0028266488 scopus 로고
    • Short- and long-term treatment with indomethacin causes renal phospholipid alteration: A possible explanation for indomethacin nephrotoxicity
    • Fernandez-Tome, M.C., and Sterin-Speziale, N.B. (1994) Short- and long-term treatment with indomethacin causes renal phospholipid alteration: a possible explanation for indomethacin nephrotoxicity. Pharmacology 48, 341-348.
    • (1994) Pharmacology , vol.48 , pp. 341-348
    • Fernandez-Tome, M.C.1    Sterin-Speziale, N.B.2
  • 15
    • 0036314217 scopus 로고    scopus 로고
    • Kidney Injury Molecule-1 (KIM-1): A novel biomarker for human renal proximal tubule injury
    • Han, W.K., Bailly, V., Abichandani, R., Thadhani, R., and Bonventre, J.V. (2002) Kidney Injury Molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury. Kidney Int. 62, 237-244.
    • (2002) Kidney Int , vol.62 , pp. 237-244
    • Han, W.K.1    Bailly, V.2    Abichandani, R.3    Thadhani, R.4    Bonventre, J.V.5
  • 16
    • 3042570252 scopus 로고    scopus 로고
    • Discovery of protein biomarkers for renal diseases
    • Hewitt, S.M., Dear, J., and Star, R.A. (2004) Discovery of protein biomarkers for renal diseases. J. Am. Soc. Nephrol. 15, 1677-1689.
    • (2004) J. Am. Soc. Nephrol , vol.15 , pp. 1677-1689
    • Hewitt, S.M.1    Dear, J.2    Star, R.A.3
  • 17
    • 0029124742 scopus 로고
    • Clusterin: Physiologic and pathophysiologic considerations
    • Rosenberg, M.E. and Silkensen, J. (1995) Clusterin: physiologic and pathophysiologic considerations. Int. J. Biochem. Cell. Biol. 27, 633-645.
    • (1995) Int. J. Biochem. Cell. Biol , vol.27 , pp. 633-645
    • Rosenberg, M.E.1    Silkensen, J.2
  • 20
    • 4143131083 scopus 로고    scopus 로고
    • Biomarkers of congenital obstructive nephropathy: Past, present and future
    • Chevalier, R.L. (2004) Biomarkers of congenital obstructive nephropathy: past, present and future. J. Urol. 172, 852-857.
    • (2004) J. Urol , vol.172 , pp. 852-857
    • Chevalier, R.L.1
  • 21
    • 0032056008 scopus 로고    scopus 로고
    • The cyclosporine A-induced decrease in rat renal calbindin-D28kDa protein as a consequence of a decrease in its mRNA
    • Grenet, O., Varela, M.C., Staedtler, F., and Steiner, S. (1998) The cyclosporine A-induced decrease in rat renal calbindin-D28kDa protein as a consequence of a decrease in its mRNA. Biochem. Pharmacol. 55, 1131-1133.
    • (1998) Biochem. Pharmacol , vol.55 , pp. 1131-1133
    • Grenet, O.1    Varela, M.C.2    Staedtler, F.3    Steiner, S.4
  • 22
    • 0030904457 scopus 로고    scopus 로고
    • Clinical cardiotoxicity following anthracycline treatment for childhood cancer. the pediatric oncology group experience
    • Krischer, J.P., Epstein, S., Cuthbertson, D.D., Goorin, A.M., Epstein, M.L., and Lipshultz, S.E. (1997) Clinical cardiotoxicity following anthracycline treatment for childhood cancer. the pediatric oncology group experience. J. Clin. Oncol. 15, 1544-1552.
    • (1997) J. Clin. Oncol , vol.15 , pp. 1544-1552
    • Krischer, J.P.1    Epstein, S.2    Cuthbertson, D.D.3    Goorin, A.M.4    Epstein, M.L.5    Lipshultz, S.E.6
  • 23
    • 0036784463 scopus 로고    scopus 로고
    • Trastuzumab-associated cardiotoxicity
    • Keefe, D.L. (2002) Trastuzumab-associated cardiotoxicity. Cancer 95, 1592-1600.
    • (2002) Cancer , vol.95 , pp. 1592-1600
    • Keefe, D.L.1
  • 24
    • 0028001641 scopus 로고
    • Cardiotoxicity as a doselimiting factor in a schedule of high dose bolus therapy with interleukin-2 and alpha-interferon. An unexpectedly frequent complication
    • Kruit, W.H., Punt, K.J., Goey, S.H., de Mulder, P.H., van Hoogenhuyze, D.C., Henzen-Logmans, S.C., and Stoter, G. (1994) Cardiotoxicity as a doselimiting factor in a schedule of high dose bolus therapy with interleukin-2 and alpha-interferon. An unexpectedly frequent complication. Cancer 74, 2850-2856.
    • (1994) Cancer , vol.74 , pp. 2850-2856
    • Kruit, W.H.1    Punt, K.J.2    Goey, S.H.3    de Mulder, P.H.4    van Hoogenhuyze, D.C.5    Henzen-Logmans, S.C.6    Stoter, G.7
  • 26
    • 14544268139 scopus 로고    scopus 로고
    • QT prolongation through hERG K(+) channel blockade: Current knowledge and strategies for the early prediction during drug development
    • Recanatini, M., Poluzzi, E., Masetti, M., Cavalli, A., and De Ponti, F. (2005) QT prolongation through hERG K(+) channel blockade: current knowledge and strategies for the early prediction during drug development. Med. Res. Rev. 25, 133-166.
    • (2005) Med. Res. Rev , vol.25 , pp. 133-166
    • Recanatini, M.1    Poluzzi, E.2    Masetti, M.3    Cavalli, A.4    De Ponti, F.5
  • 29
    • 0035044440 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of cardiotoxicity
    • Kang, Y.J. (2001) Molecular and cellular mechanisms of cardiotoxicity. Environ. Health Perspect. 109 (Suppl 1), 27-34.
    • (2001) Environ. Health Perspect , vol.109 , Issue.SUPPL. 1 , pp. 27-34
    • Kang, Y.J.1
  • 32
    • 0026349336 scopus 로고
    • Regulation of cardiac gene expression during myocardial growth and hypertrophy: Molecular studies of an adaptive physiologic response
    • Chien, K.R., Knowlton, K.U., Zhu, H., and Chien, S. (1991) Regulation of cardiac gene expression during myocardial growth and hypertrophy: molecular studies of an adaptive physiologic response. FASEB J. 5, 3037-3046.
    • (1991) FASEB J , vol.5 , pp. 3037-3046
    • Chien, K.R.1    Knowlton, K.U.2    Zhu, H.3    Chien, S.4
  • 33
    • 0028987620 scopus 로고
    • Proto-oncogene expression in the isolated working rat heart: Combination of pressure and volume overload with norepinephrine
    • Kolbeck-Ruhmkorff, C. and Zimmer, H.G. (1995) Proto-oncogene expression in the isolated working rat heart: combination of pressure and volume overload with norepinephrine. J. Mol. Cell. Cardiol. 27, 501-511.
    • (1995) J. Mol. Cell. Cardiol , vol.27 , pp. 501-511
    • Kolbeck-Ruhmkorff, C.1    Zimmer, H.G.2
  • 34
    • 0041342015 scopus 로고    scopus 로고
    • Drug-induced hepatotoxicity
    • Lee, W.M. (2003) Drug-induced hepatotoxicity. N. Engl. J. Med. 349, 474-485.
    • (2003) N. Engl. J. Med , vol.349 , pp. 474-485
    • Lee, W.M.1
  • 36
    • 0034685195 scopus 로고    scopus 로고
    • Serum aminotransferase concentration as evidence of hepatocellular damage
    • Kew, M.C. (2000) Serum aminotransferase concentration as evidence of hepatocellular damage. Lancet 355, 591-592.
    • (2000) Lancet , vol.355 , pp. 591-592
    • Kew, M.C.1
  • 37
    • 0037008076 scopus 로고    scopus 로고
    • Alanine aminotransferase levels: What's normal?
    • Kaplan, M.M. (2002) Alanine aminotransferase levels: what's normal? Ann. Intern. Med. 137, 49-51.
    • (2002) Ann. Intern. Med , vol.137 , pp. 49-51
    • Kaplan, M.M.1
  • 38
    • 1542437234 scopus 로고    scopus 로고
    • Expression pattern and regulation of heme oxygenase-1/heat shock protein 32 in human liver cells
    • Bauer, I., Rensing, H., Florax, A., Ulrich, C., Pistorius, G., Redl, H., and Bauer, M. (2003) Expression pattern and regulation of heme oxygenase-1/heat shock protein 32 in human liver cells. Shock 20, 116-122.
    • (2003) Shock , vol.20 , pp. 116-122
    • Bauer, I.1    Rensing, H.2    Florax, A.3    Ulrich, C.4    Pistorius, G.5    Redl, H.6    Bauer, M.7
  • 39
    • 0036847809 scopus 로고    scopus 로고
    • Lipopolysaccharide-binding protein and lipopolysaccharide receptor CD14 gene expression after thermal injury and its potential mechanism(s)
    • Fang, C.W., Yao, Y.M., Shi, Z.G., Yu, Y., Wu, Y., Lu, L.R., and Sheng, Z.Y. (2002) Lipopolysaccharide-binding protein and lipopolysaccharide receptor CD14 gene expression after thermal injury and its potential mechanism(s). J. Trauma 53, 957-967.
    • (2002) J. Trauma , vol.53 , pp. 957-967
    • Fang, C.W.1    Yao, Y.M.2    Shi, Z.G.3    Yu, Y.4    Wu, Y.5    Lu, L.R.6    Sheng, Z.Y.7
  • 40
    • 11144314814 scopus 로고    scopus 로고
    • Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron
    • Flo, T.H., Smith, K.D., Sato, S., Rodriguez, D.J., Holmes, M.A., Strong, R.K., et al. (2004) Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron. Nature 432, 917-921.
    • (2004) Nature , vol.432 , pp. 917-921
    • Flo, T.H.1    Smith, K.D.2    Sato, S.3    Rodriguez, D.J.4    Holmes, M.A.5    Strong, R.K.6
  • 42
    • 14844360651 scopus 로고    scopus 로고
    • The transcriptome in blood: Challenges and solutions for robust expression profiling
    • Fan, H. and Hegde, P.S. (2005) The transcriptome in blood: challenges and solutions for robust expression profiling. Curr. Mol. Med. 5, 3-10.
    • (2005) Curr. Mol. Med , vol.5 , pp. 3-10
    • Fan, H.1    Hegde, P.S.2
  • 43
    • 85069276612 scopus 로고    scopus 로고
    • ® Expression Profiling Santa Clara, CA.
    • ® Expression Profiling Santa Clara, CA.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.