Vaccination using radiation- or genetically attenuated live sporozoites

Methods in Molecular Biology

Volumn 923, Issue , 2013, Pages 549-566

  Vaughan, Ashley M ^a   Kappe, Stefan H I ^a  

^a NONE

Author keywords

Cross stage immunity; Genetically attenuated parasite; Heterologous challenge; Liver stage; Protective immunity; Radiation attenuated sporozoite

Indexed keywords

MALARIA VACCINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; IMMUNITY; IMMUNIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIATION ATTENUATION; RODENT MALARIA; SALIVARY GLAND; SPOROZOITE; VACCINATION;

EID: 84934439683     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-62703-26-7_38     Document Type: Article

References (23)

1. Hill AV et al (2010) Prime-boost vectored malaria vaccines: Progress and prospects. Hum Vaccin 6:78-83
2. Kappe SH et al (2010) That was then but this is now: Malaria research in the time of an eradication agenda. Science 328:862-866
3. Nussenzweig RS et al (1967) Protective immunity produced by the injection of x-irradiated sporozoites of Plasmodium berghei. Nature 216:160-162
4. Clyde DF (1975) Immunization of man against falciparum and vivax malaria by use of attenuated sporozoites. Am J Trop Med Hyg 24: 397-401
5. Hoffman SL et al (2002) Protection of humans against malaria by immunization with radiation-attenuated Plasmodium falciparum sporozoites. J Infect Dis 185:1155-1164
6. Hafalla JC et al (2006) Protective and pathogenic roles of CD8+ T cells during malaria infection. Parasite Immunol 28:15-24
7. Crompton PD et al (2010) Advances and challenges in malaria vaccine development. J Clin Invest 120:4168-4178
8. Vaughan AM et al (2010) Genetically engineered, attenuated whole-cell vaccine approaches for malaria. Hum Vaccin 6:107-113
9. VanBuskirk KM et al (2009) Preerythrocytic, live-attenuated Plasmodium falciparum vaccine candidates by design. Proc Natl Acad Sci USA 106:13004-13009
10. Mueller AK et al (2005) Plasmodium liver stage developmental arrest by depletion of a protein at the parasite-host interface. Proc Natl Acad Sci USA 102:3022-3027
11. Mueller AK et al (2005) Genetically modified Plasmodium parasites as a protective experimental malaria vaccine. Nature 433:164-167
12. Aly AS et al (2008) Targeted deletion of SAP1 abolishes the expression of infectivity factors necessary for successful malaria parasite liver infection. Mol Microbiol 69:152-163
13. Silvie O et al (2008) A sporozoite asparaginerich protein controls initiation of Plasmodium liver stage development. PLoS Pathog 4:e1000086
14. Labaied M et al (2007) Plasmodium yoelii sporozoites with simultaneous deletion of P52 and P36 are completely attenuated and confer sterile immunity against infection. Infect Immun 75:3758-3768
15. Vaughan AM et al (2009) Type II fatty acid synthesis is essential only for malaria parasite late liver stage development. Cell Microbiol 11:506-520
16. Krzych U, Schwenk J (2005) The dissection of CD8 T cells during liver-stage infection. Curr Top Microbiol Immunol 297:1-24
17. Overstreet MG et al (2008) Protective CD8 T cells against Plasmodium liver stages: Immunobiology of an 'unnatural' immune response. Immunol Rev 225:272-283
18. Tarun AS et al (2007) Protracted sterile protection with Plasmodium yoelii pre-erythrocytic genetically attenuated parasite malaria vaccines is independent of significant liver-stage persistence and is mediated by CD8+ T cells. J Infect Dis 196:608-616
19. Tsuji M (2010) A retrospective evaluation of the role of T cells in the development of malaria vaccine. Exp Parasitol 126:421-425
20. van Dijk MR et al (2005) Genetically attenuated, P36p-deficient malarial sporozoites induce protective immunity and apoptosis of infected liver cells. Proc Natl Acad Sci USA 102:12194-12199
21. Butler NS et al (2011) Superior antimalarial immunity after vaccination with late liver stagearresting genetically attenuated parasites. Cell Host Microbe 9:451-462
22. Schmidt NW et al (2010) Extreme CD8 T cell requirements for anti-malarial liver-stage immunity following immunization with radiation attenuated sporozoites. PLoS Pathog 6:e1000998
23. Kaech SM et al (2002) Molecular and functional profiling of memory CD8 T cell differentiation. Cell 111:837-851