-
1
-
-
84872380261
-
Sequence kernel association test for quantitative traits in family samples
-
Chen H, Meigs JB, Dupuis J. 2013. Sequence kernel association test for quantitative traits in family samples. Genet Epidemiol 37:196-204.
-
(2013)
Genet Epidemiol
, vol.37
, pp. 196-204
-
-
Chen, H.1
Meigs, J.B.2
Dupuis, J.3
-
2
-
-
80051968181
-
Needles in stacks of needles: finding disease-causal variants in a wealth of genomic data
-
Cooper GM, Shendure J. 2011. Needles in stacks of needles: finding disease-causal variants in a wealth of genomic data. Nat Rev Genet 12:628-640.
-
(2011)
Nat Rev Genet
, vol.12
, pp. 628-640
-
-
Cooper, G.M.1
Shendure, J.2
-
3
-
-
84872389630
-
Rare variant analysis for family-based design
-
De G, Yip W, Ionita-Laza I, Laird N. 2013. Rare variant analysis for family-based design. PloS One 8:e48495.
-
(2013)
PloS One
, vol.8
, pp. e48495
-
-
De, G.1
Yip, W.2
Ionita-Laza, I.3
Laird, N.4
-
4
-
-
0032714352
-
Genomic control for association studies
-
Devlin B, Roeder K. 1999. Genomic control for association studies. Biometrics 55:997-1004.
-
(1999)
Biometrics
, vol.55
, pp. 997-1004
-
-
Devlin, B.1
Roeder, K.2
-
5
-
-
84862260138
-
Two adaptive weighting methods to test for rare variant associations in family-based designs
-
Fang S, Sha Q, Zhang S. 2012. Two adaptive weighting methods to test for rare variant associations in family-based designs. Genet Epidemiol 36:499-507.
-
(2012)
Genet Epidemiol
, vol.36
, pp. 499-507
-
-
Fang, S.1
Sha, Q.2
Zhang, S.3
-
6
-
-
1542373634
-
Increasing the power and efficiency of disease-marker case-control association studies through use of allele-sharing information
-
Fingerlin TE, Boehnke M, Abecasis GR. 2004. Increasing the power and efficiency of disease-marker case-control association studies through use of allele-sharing information. Am J Hum Genet 74:432-443.
-
(2004)
Am J Hum Genet
, vol.74
, pp. 432-443
-
-
Fingerlin, T.E.1
Boehnke, M.2
Abecasis, G.R.3
-
7
-
-
84869102628
-
Identifying plausible genetic models based on association and linkage results: application to type 2 diabetes
-
Guan W, Boehnke M, Pluzhnikov A, Cox NJ, Scott LJ. 2012. Identifying plausible genetic models based on association and linkage results: application to type 2 diabetes. Genet Epidemiol 36:820-828.
-
(2012)
Genet Epidemiol
, vol.36
, pp. 820-828
-
-
Guan, W.1
Boehnke, M.2
Pluzhnikov, A.3
Cox, N.J.4
Scott, L.J.5
-
8
-
-
84862203211
-
Detecting rare variants for quantitative traits using nuclear families
-
Guo W, Shugart YY. 2012. Detecting rare variants for quantitative traits using nuclear families. Hum Hered 73:148-158.
-
(2012)
Hum Hered
, vol.73
, pp. 148-158
-
-
Guo, W.1
Shugart, Y.Y.2
-
9
-
-
84875052549
-
Familial cosegregation of rare genetic variants with disease in complex disorders
-
Helbig I, Hodge SE, Ottman R. 2013. Familial cosegregation of rare genetic variants with disease in complex disorders. Eur J Hum Genet 21:444-450.
-
(2013)
Eur J Hum Genet
, vol.21
, pp. 444-450
-
-
Helbig, I.1
Hodge, S.E.2
Ottman, R.3
-
10
-
-
58549090910
-
Confirmation of HLA class II independent type 1 diabetes associations in the major histocompatibility complex including HLA-B and HLA-A
-
Howson JMM, Walker NM, Clayton D, Todd JA. 2009. Confirmation of HLA class II independent type 1 diabetes associations in the major histocompatibility complex including HLA-B and HLA-A. Diabetes Obes Metab 11(Suppl 1):31-45.
-
(2009)
Diabetes Obes Metab
, vol.11
, pp. 31-45
-
-
Howson, J.M.M.1
Walker, N.M.2
Clayton, D.3
Todd, J.A.4
-
11
-
-
81255175654
-
Study designs for identification of rare disease variants in complex diseases: the utility of family-based designs
-
Ionita-Laza I, Ottman R. 2011. Study designs for identification of rare disease variants in complex diseases: the utility of family-based designs. Genetics 189:1061-1068.
-
(2011)
Genetics
, vol.189
, pp. 1061-1068
-
-
Ionita-Laza, I.1
Ottman, R.2
-
12
-
-
51749109039
-
Calculation of IBD probabilities with dense SNP or sequence data
-
Keith JM, McRae A, Duffy D, Mengersen K, Visscher PM. 2008. Calculation of IBD probabilities with dense SNP or sequence data. Genet Epidemiol 32:513-519.
-
(2008)
Genet Epidemiol
, vol.32
, pp. 513-519
-
-
Keith, J.M.1
McRae, A.2
Duffy, D.3
Mengersen, K.4
Visscher, P.M.5
-
13
-
-
33646188852
-
Family-based designs in the age of large-scale gene-association studies
-
Laird NM, Lange C. 2006. Family-based designs in the age of large-scale gene-association studies. Nat Rev Genet 7:385-394.
-
(2006)
Nat Rev Genet
, vol.7
, pp. 385-394
-
-
Laird, N.M.1
Lange, C.2
-
14
-
-
50949095168
-
Methods for detecting associations with rare variants for common diseases: application to analysis of sequence data
-
Li B, Leal SM. 2008. Methods for detecting associations with rare variants for common diseases: application to analysis of sequence data. Am J Hum Genet 83:311-321.
-
(2008)
Am J Hum Genet
, vol.83
, pp. 311-321
-
-
Li, B.1
Leal, S.M.2
-
15
-
-
84875667844
-
Marbled inflation from population structure in gene-based association studies with rare variants
-
Liu Q, Nicolae DL, Chen LS. 2013. Marbled inflation from population structure in gene-based association studies with rare variants. Genet Epidemiol 37:286-292.
-
(2013)
Genet Epidemiol
, vol.37
, pp. 286-292
-
-
Liu, Q.1
Nicolae, D.L.2
Chen, L.S.3
-
16
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
Manolio TA, Collins FS, Cox NJ, Goldstein DB, Hindorff LA, Hunter DJ, McCarthy MI, Ramos EM, Cardon LR, Chakravarti A, et al. 2009. Finding the missing heritability of complex diseases. Nature 461:747-753.
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.A.1
Collins, F.S.2
Cox, N.J.3
Goldstein, D.B.4
Hindorff, L.A.5
Hunter, D.J.6
McCarthy, M.I.7
Ramos, E.M.8
Cardon, L.R.9
Chakravarti, A.10
-
17
-
-
84857641821
-
Differential confounding of rare and common variants in spatially structured populations
-
Mathieson I, McVean G. 2012. Differential confounding of rare and common variants in spatially structured populations. Nat Genet 44:243-246.
-
(2012)
Nat Genet
, vol.44
, pp. 243-246
-
-
Mathieson, I.1
McVean, G.2
-
18
-
-
84863541347
-
An abundance of rare functional variants in 202 drug target genes sequenced in 14002 people
-
Nelson MR, Wegmann D, Ehm MG, Kessner D, St Jean P, Verzilli C, Shen J, Tang Z, Bacanu SA, Fraser D, et al. 2012. An abundance of rare functional variants in 202 drug target genes sequenced in 14002 people. Science 337:100-104.
-
(2012)
Science
, vol.337
, pp. 100-104
-
-
Nelson, M.R.1
Wegmann, D.2
Ehm, M.G.3
Kessner, D.4
St Jean, P.5
Verzilli, C.6
Shen, J.7
Tang, Z.8
Bacanu, S.A.9
Fraser, D.10
-
19
-
-
73349110071
-
Exome sequencing identifies the cause of a mendelian disorder
-
Ng SB, Buckingham KJ, Lee C, Bigham AW, Tabor HK, Dent KM, Huff CD, Shannon PT, Jabs EW, Nickerson DA, et al. 2010. Exome sequencing identifies the cause of a mendelian disorder. Nat Genet 42:30-35.
-
(2010)
Nat Genet
, vol.42
, pp. 30-35
-
-
Ng, S.B.1
Buckingham, K.J.2
Lee, C.3
Bigham, A.W.4
Tabor, H.K.5
Dent, K.M.6
Huff, C.D.7
Shannon, P.T.8
Jabs, E.W.9
Nickerson, D.A.10
-
20
-
-
70249111091
-
Targeted capture and massively parallel sequencing of 12 human exomes
-
Ng SB, Turner EH, Robertson PD, Flygare SD, Bigham AW, Lee C, Shaffer T, Wong M, Bhattacharjee A, Eichler EE, et al. 2009. Targeted capture and massively parallel sequencing of 12 human exomes. Nature 461:272-276.
-
(2009)
Nature
, vol.461
, pp. 272-276
-
-
Ng, S.B.1
Turner, E.H.2
Robertson, P.D.3
Flygare, S.D.4
Bigham, A.W.5
Lee, C.6
Shaffer, T.7
Wong, M.8
Bhattacharjee, A.9
Eichler, E.E.10
-
21
-
-
77953416140
-
Power analysis for case-control association studies of samples with known family histories
-
Peng B, Li B, Han Y, Amos CI. 2010. Power analysis for case-control association studies of samples with known family histories. Hum Genet 127:699-704.
-
(2010)
Hum Genet
, vol.127
, pp. 699-704
-
-
Peng, B.1
Li, B.2
Han, Y.3
Amos, C.I.4
-
22
-
-
33746512512
-
Principal components analysis corrects for stratification in genome-wide association studies
-
Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, Reich D. 2006. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 38:904-909.
-
(2006)
Nat Genet
, vol.38
, pp. 904-909
-
-
Price, A.L.1
Patterson, N.J.2
Plenge, R.M.3
Weinblatt, M.E.4
Shadick, N.A.5
Reich, D.6
-
23
-
-
77953121877
-
Pooled association tests for rare variants in exon-resequencing studies
-
Price AL, Kryukov GV, de Bakker PI, Purcell SM, Staples J, Wei LJ, Sunyaev SR. 2010. Pooled association tests for rare variants in exon-resequencing studies. Am J Hum Genet 86:832-838.
-
(2010)
Am J Hum Genet
, vol.86
, pp. 832-838
-
-
Price, A.L.1
Kryukov, G.V.2
de Bakker, P.I.3
Purcell, S.M.4
Staples, J.5
Wei, L.J.6
Sunyaev, S.R.7
-
24
-
-
12244273672
-
A genome-wide affected sibpair linkage analysis of hypertension: the HyperGEN network
-
Rao DC, Province MA, Leppert MF, Oberman Al, Heiss G, Ellison RC, Arnett DK, Eckfeldt JH, Schwander K, Mockrin SC, Hunt SC. 2003. A genome-wide affected sibpair linkage analysis of hypertension: the HyperGEN network. Am J Hypertens 16:148-150.
-
(2003)
Am J Hypertens
, vol.16
, pp. 148-150
-
-
Rao, D.C.1
Province, M.A.2
Leppert, M.F.3
Oberman, A.4
Heiss, G.5
Ellison, R.C.6
Arnett, D.K.7
Eckfeldt, J.H.8
Schwander, K.9
Mockrin, S.C.10
Hunt, S.C.11
-
25
-
-
0025019555
-
Linkage strategies for genetically complex traits. I. Multilocus models
-
Risch N. 1990. Linkage strategies for genetically complex traits. I. Multilocus models. Am J Hum Genet 46:222-228.
-
(1990)
Am J Hum Genet
, vol.46
, pp. 222-228
-
-
Risch, N.1
-
26
-
-
0035528925
-
Implications of multilocus inheritance for gene-disease association studies
-
Risch N. 2001. Implications of multilocus inheritance for gene-disease association studies. Theor Popul Biol 60:215-220.
-
(2001)
Theor Popul Biol
, vol.60
, pp. 215-220
-
-
Risch, N.1
-
27
-
-
27544497650
-
Calibrating a coalescent simulation of human genome sequence variation
-
Schaffner SF, Foo C, Gabriel S, Reich D, Daly MJ, Altshuler D. 2005. Calibrating a coalescent simulation of human genome sequence variation. Genome Res 15:1576-1583.
-
(2005)
Genome Res
, vol.15
, pp. 1576-1583
-
-
Schaffner, S.F.1
Foo, C.2
Gabriel, S.3
Reich, D.4
Daly, M.J.5
Altshuler, D.6
-
28
-
-
84869123399
-
SNP set association analysis for familial data
-
Schifano ED, Epstein MP, Bielak LF, Jhun MA, Kardia SL, Peyser PA, Lin X. 2012. SNP set association analysis for familial data. Genet Epidemiol 36:797-810.
-
(2012)
Genet Epidemiol
, vol.36
, pp. 797-810
-
-
Schifano, E.D.1
Epstein, M.P.2
Bielak, L.F.3
Jhun, M.A.4
Kardia, S.L.5
Peyser, P.A.6
Lin, X.7
-
29
-
-
84869867641
-
Weighted pedigree-based statistics for testing the association of rare variants
-
Shugart YY, Zhu Y, Guo W, Xiong M. 2012. Weighted pedigree-based statistics for testing the association of rare variants. BMC Genomics 13:667.
-
(2012)
BMC Genomics
, vol.13
, pp. 667
-
-
Shugart, Y.Y.1
Zhu, Y.2
Guo, W.3
Xiong, M.4
-
30
-
-
80051499915
-
Rare-variant association testing for sequencing data with the sequence kernel association test
-
Wu MC, Lee S, Cai T, Li Y, Boehnke M, Lin X. 2011. Rare-variant association testing for sequencing data with the sequence kernel association test. Am J Hum Genet 89:82-93.
-
(2011)
Am J Hum Genet
, vol.89
, pp. 82-93
-
-
Wu, M.C.1
Lee, S.2
Cai, T.3
Li, Y.4
Boehnke, M.5
Lin, X.6
-
31
-
-
78249243049
-
Extending rare-variant testing strategies: analysis of noncoding sequence and imputed genotypes
-
Zawistowski M, Gopalakrishnan S, Ding J, Li Y, Grimm S, Zöllner S. 2014. Extending rare-variant testing strategies: analysis of noncoding sequence and imputed genotypes. Am J Hum Genet 87:604-617.
-
(2014)
Am J Hum Genet
, vol.87
, pp. 604-617
-
-
Zawistowski, M.1
Gopalakrishnan, S.2
Ding, J.3
Li, Y.4
Grimm, S.5
Zöllner, S.6
-
32
-
-
84906262908
-
Sources of population stratification in gene-based rare variant tests identified by the joint site frequency spectrum
-
Zawistowski M, Reppell M, Wegmann M, St. Jean PL, Ehm MG, Nelson MR, Novembre J, Zöllner S. 2014. Sources of population stratification in gene-based rare variant tests identified by the joint site frequency spectrum. Eur J Hum Genet 22:1137-1144.
-
(2014)
Eur J Hum Genet
, vol.22
, pp. 1137-1144
-
-
Zawistowski, M.1
Reppell, M.2
Wegmann, M.3
St Jean, P.L.4
Ehm, M.G.5
Nelson, M.R.6
Novembre, J.7
Zöllner, S.8
-
33
-
-
84866538350
-
Sampling strategies for rare variant tests in case-control studies
-
Zöllner S. 2012. Sampling strategies for rare variant tests in case-control studies. Eur J Hum Genet 20:1085-1091.
-
(2012)
Eur J Hum Genet
, vol.20
, pp. 1085-1091
-
-
Zöllner, S.1
|