Polymorphisms of NF B1 and i B α and Their Synergistic Effect on Nasopharyngeal Carcinoma Susceptibility

BioMed Research International

Volumn 2015, Issue , 2015, Pages

  Liu, Yehua ^a   Qiu, Fuman ^a   Yang, Lei ^a   Yang, Rongrong ^a   Yang, Xiaorong ^a   Huang, Dongsheng ^a   Fang, Wenxiang ^a   Zhang, Lisha ^a   Jiang, Qingping ^a   Zhang, Lan ^a   Zhou, Yifeng ^b   Lu, Jiachun ^a  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

^b MEDICAL COLLEGE OF SOOCHOW UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

I KAPPA B KINASE ALPHA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MICRORNA; MICRORNA 449A; MICRORNA HSA; NUCLEAR FACTOR KAPPA B 1; UNCLASSIFIED DRUG; I KAPPA B; LUCIFERASE; NFKBIA PROTEIN, HUMAN;

ADULT; ARTICLE; CANCER PATIENT; CANCER RISK; CANCER SUSCEPTIBILITY; CHINESE; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; GENE FREQUENCY; GENETIC VARIABILITY; GENOTYPE; HUMAN; LUCIFERASE ASSAY; MAJOR CLINICAL STUDY; MALE; NASOPHARYNX CARCINOMA; PROTEIN EXPRESSION; SINGLE NUCLEOTIDE POLYMORPHISM; CASE CONTROL STUDY; ENZYME ASSAY; GENETIC PREDISPOSITION; GENETICS; METABOLISM; MIDDLE AGED; MOLECULAR GENETICS; NASOPHARYNX TUMOR; NUCLEOTIDE SEQUENCE; RISK FACTOR;

BASE SEQUENCE; CASE-CONTROL STUDIES; ENZYME ASSAYS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; I-KAPPA B PROTEINS; LUCIFERASES; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; NASOPHARYNGEAL NEOPLASMS; NF-KAPPA B P50 SUBUNIT; NF-KAPPAB INHIBITOR ALPHA; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 84934312288     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2015/362542     Document Type: Article

References (44)

1. J.-P. Liu, L. Cassar, A. Pinto, and H. Li, "Mechanisms of cell immortalization mediated by EB viral activation of telomerase in nasopharyngeal carcinoma", Cell Research, vol. 16, no. 10, pp. 809-817, 2006.
2. A. Jemal, F. Bray, M. M. Center, J. Ferlay, E. Ward, and D. Forman, "Global cancer statistics", CA: A Cancer Journal for Clinicians, vol. 61, no. 2, pp. 69-90, 2011.
3. W.-H. Jia, Q.-H. Huang, J. Liao et al., "Trends in incidence and mortality of nasopharyngeal carcinoma over a 20-25 year period (1978/1983-2002) in Sihui and Cangwu counties in Southern China", BMC Cancer, vol. 6, article 178, 2006.
4. M. C. Yu and J.-M. Yuan, "Epidemiology of nasopharyngeal carcinoma", Seminars in Cancer Biology, vol. 12, no. 6, pp. 421-429, 2002.
5. E. T. Chang and H.-O. Adami, "The enigmatic epidemiology of nasopharyngeal carcinoma", Cancer Epidemiology Biomarkers and Prevention, vol. 15, no. 10, pp. 1765-1777, 2006.
6. M. A. Vasef, A. Ferlito, and L. M. Weiss, "Nasopharyngeal carcinoma, with emphasis on its relationship to Epstein-Barr virus", Annals of Otology, Rhinology and Laryngology, vol. 106, no. 4, pp. 348-356, 1997.
7. R. W. Armstrong, P. B. Imrey, M. S. Lye, M. J. Armstrong, M. C. Yu, and S. Sani, "Nasopharyngeal carcinoma in Malaysian Chinese: salted fish and other dietary exposures", International Journal of Cancer, vol. 77, no. 2, pp. 228-235, 1998.
8. X. Ji, W. Zhang, C. Xie, B. Wang, G. Zhang, and F. Zhou, "Nasopharyngeal carcinoma risk by histologic type in central China: impact of smoking, alcohol and family history", International Journal of Cancer, vol. 129, no. 3, pp. 724-732, 2011.
9. H. Zheng, L. L. Li, D. S. Hu, X. Y. Deng, and Y. Cao, "Role of Epstein-Barr virus encoded latent membrane protein 1 in the carcinogenesis of nasopharyngeal carcinoma", Cellular & Molecular Immunology, vol. 4, no. 3, pp. 185-196, 2007.
10. J. L. Arbiser, "Implications of Epstein-Barr Virus (EBV) - induced carcinogenesis on cutaneous inflammation and carcinogenesis: evidence of recurring patterns of angiogenesis and signal transduction", Journal of Investigative Dermatology, vol. 124, no. 5, pp. xi-xii, 2005.
11. F. R. Greten, L. Eckmann, T. F. Greten et al., "IKKβ links inflammation and tumorigenesis in a mouse model of colitis-associated cancer", Cell, vol. 118, no. 3, pp. 285-296, 2004.
12. E. Pikarsky, R. M. Porat, I. Stein et al., "NF-κB functions as a tumour promoter in inflammation-associated cancer", Nature, vol. 431, no. 7007, pp. 461-466, 2004.
13. M. Karin, "Nuclear factor-κB in cancer development and progression", Nature, vol. 441, no. 7092, pp. 431-436, 2006.
14. M. Karin, "NF-kappaB as a critical link between inflammation and cancer", Cold Spring Harbor Perspectives in Biology, vol. 1, no. 5, article ID a000141, 2009.
15. B. B. Aggarwal, Y. Takada, S. Shishodia et al., "Nuclear transcription factor NF-kappa B: role in biology and medicine", Indian Journal of Experimental Biology, vol. 42, no. 4, pp. 341-353, 2004.
16. M. M. Chaturvedi, B. Sung, V. R. Yadav, R. Kannappan, and B. B. Aggarwal, "NF-κB addiction and its role in cancer: one size does not fit all", Oncogene, vol. 30, no. 14, pp. 1615-1630, 2011.
17. M. Karin and F. R. Greten, "NF-κB: linking inflammation and immunity to cancer development and progression", Nature Reviews Immunology, vol. 5, no. 10, pp. 749-759, 2005.
18. F. Chen, V. Castranova, X. Shi, and L. M. Demers, "New insights into the role of nuclear factor-κB, a ubiquitous transcription factor in the initiation of diseases", Clinical Chemistry, vol. 45, no. 1, pp. 7-17, 1999.
19. M. S. Hayden, A. P. West, and S. Ghosh, "SnapShot: NF-κB signaling pathways", Cell, vol. 127, no. 6, pp. 1286.e1-1286.e2, 2006.
20. A. S. Karban, T. Okazaki, C. I. M. Panhuysen et al., "Functional annotation of a novel NFKB1 promoter polymorphism that increases risk for ulcerative colitis", Human Molecular Genetics, vol. 13, no. 1, pp. 35-45, 2004.
21. Y. He, H. Zhang, J. Yin et al., "IkappaBalpha gene promoter polymorphisms are associated with hepatocarcinogenesis in patients infected with hepatitis B virus genotype C", Carcinogenesis, vol. 30, no. 11, pp. 1916-1922, 2009.
22. S. Song, D. Chen, J. Lu et al., "NFkappaB1 and NFkappaBIA polymorphisms are associated with increased risk for sporadic colorectal cancer in a southern Chinese population", PLoS ONE, vol. 6, no. 6, article ID e21726, 2011.
23. D. Huang, L. Yang, Y. Liu et al., "Functional polymorphisms in NFκB1/IκBα predict risks of chronic obstructive pulmonary disease and lung cancer in Chinese", Human Genetics, vol. 132, no. 4, pp. 451-460, 2013.
24. L. Yang, B. Liu, F. Qiu et al., "The effect of functional MAPKAPK2 copy number variation CNV-30450 on elevating nasopharyngeal carcinoma risk is modulated by EBV infection", Carcinogenesis, vol. 35, no. 1, pp. 46-52, 2014.
25. J. Lu, L. Yang, H. Zhao et al., "The polymorphism and haplotypes of PIN1 gene are associated with the risk of lung cancer in southern and eastern chinese populations", Human Mutation, vol. 32, no. 11, pp. 1299-1308, 2011.
26. B. Liu, D. Chen, L. Yang et al., "A functional variant (-1304T>G) in the MKK4 promoter contributes to a decreased risk of lung cancer by increasing the promoter activity", Carcinogenesis, vol. 31, no. 8, pp. 1405-1411, 2010.
27. L. Yang, Y. Li, M. Cheng et al., "A functional polymorphism at microRNA-629-binding site in the 3-untranslated region of nbs1 gene confers an increased risk of lung cancer in southern and eastern chinese population", Carcinogenesis, vol. 33, no. 2, pp. 338-347, 2012.
28. V. Sampath, M. Le, L. Lane et al., "The NFKB1 (g.-24519delATTG) variant is associated with necrotizing enterocolitis (NEC) in premature infants", Journal of Surgical Research, vol. 169, no. 1, pp. e51-e57, 2011.
29. M. Marcos, I. Pastor, R. González-Sarmiento, and F. J. Laso, "A functional polymorphism of the NFKB1 gene increases the risk for alcoholic liver cirrhosis in patients with alcohol dependence", Alcoholism: Clinical and Experimental Research, vol. 33, no. 11, pp. 1857-1862, 2009.
30. Y. H. Hung, C. C. Wu, and T. T. Ou, "IκBα promoter polymorphisms in patients with Behçet's disease", Disease Markers, vol. 28, no. 1, pp. 55-62, 2010.
31. P. Zhang, Q. Wei, X. Li et al., "A functional insertion/deletion polymorphism in the promoter region of the NFKB1 gene increases susceptibility for prostate cancer", Cancer Genetics and Cytogenetics, vol. 191, no. 2, pp. 73-77, 2009.
32. W. D. Dupont and W. D. Plummer Jr., "Power and sample size calculations. A review and computer program", Controlled Clinical Trials, vol. 11, no. 2, pp. 116-128, 1990.
33. L. L. Yates and D. C. Górecki, "The nuclear factor-kappaB (NF-κB): from a versatile transcription factor to a ubiquitous therapeutic target", Acta Biochimica Polonica, vol. 53, no. 4, pp. 651-662, 2006.
34. R. O. Escarcega, "The transcription factor NF-κB in human diseases", Revista Médica del Instituto Mexicano del Seguro Social, vol. 48, no. 1, pp. 55-60, 2010.
35. C.-C. Chen, H.-P. Liu, M. Chao et al., "NF-κB-mediated transcriptional upregulation of TNFAIP2 by the Epstein-Barr virus oncoprotein, LMP1, promotes cell motility in nasopharyngeal carcinoma", Oncogene, vol. 33, pp. 3648-3659, 2014.
36. H. J. Kim, K. W. Kim, B. P. Yu, and H. Y. Chung, "The effect of age on cyclooxygenase-2 gene expression: NF-kappaB activation and IkappaBalpha degradation", Free Radical Biology & Medicine, vol. 28, no. 5, pp. 683-692, 2000.
37. H. Abe, C. N. Hayes, H. Ochi et al., "Inverse association of IL28B genotype and liver mRNA expression of genes promoting or suppressing antiviral state", Journal of Medical Virology, vol. 83, no. 9, pp. 1597-1607, 2011.
38. K. Riemann, L. Becker, H. Struwe, H. Rübben, A. Eisenhardt, and W. Sifert, "Insertion/deletion polymorphism in the promoter of NFKB1 as a potential molecular marker for the risk of recurrence in superficial bladder cancer", International Journal of Clinical Pharmacology and Therapeutics, vol. 45, no. 8, pp. 423-430, 2007.
39. J. Gao, D. Pfeifer, L.-J. He et al., "Association of NFKBIA polymorphism with colorectal cancer risk and prognosis in Swedish and Chinese populations", Scandinavian Journal of Gastroenterology, vol. 42, no. 3, pp. 345-350, 2007.
40. D. Huang, L. Yang, Y. Liu et al., "Functional polymorphisms in NFκB1/IκBα predict risks of chronic obstructive pulmonary disease and lung cancer in Chinese", Human Genetics, vol. 132, no. 4, pp. 451-460, 2013.
41. P. Li, J. Gu, X. Yang et al., "Functional promoter-94 ins/del ATTG polymorphism in NFKB1 gene is associated with bladder cancer risk in a Chinese population", PLoS ONE, vol. 8, no. 8, article ID e71604, 2013.
42. T. Arisawa, T. Tahara, H. Shiroeda et al., "Functional promoter polymorphisms of NFKB1 influence susceptibility to the diffuse type of gastric cancer", Oncology Reports, vol. 30, no. 6, pp. 3013-3019, 2013.
43. Z. Yu, Z. Li, N. Jolicoeur et al., "Aberrant allele frequencies of the SNPs located in microRNA target sites are potentially associated with human cancers", Nucleic Acids Research, vol. 35, no. 13, pp. 4535-4541, 2007.
44. S. Wacholder, S. Chanock, M. Garcia-Closas, L. El Ghormli, and N. Rothman, "Assessing the probability that a positive report is false: an approach for molecular epidemiology studies", Journal of the National Cancer Institute, vol. 96, no. 6, pp. 434-442, 2004.