Does lysozyme play a role in the pathogenesis of COPD?

Medical Hypotheses

Volumn 84, Issue 6, 2015, Pages 551-554

  Cantor, Jerome ^a   Shteyngart, Bronislava ^a  

^a ST JOHN'S UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AEROSOLIZED HYALURONIC ACID; HYALURONIC ACID; LYSOZYME; UNCLASSIFIED DRUG;

ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL TRIAL (TOPIC); DISEASE COURSE; DISEASE PREDISPOSITION; DRUG PROTEIN BINDING; ELASTIC FIBER; ELASTOLYSIS; HUMAN; LUNG ALVEOLUS WALL; LUNG EMPHYSEMA; LUNG INJURY; NONHUMAN; PATHOGENESIS; PROTEIN FUNCTION; WATER RETENTION; BIOLOGICAL MODEL; BIOMECHANICS; ELASTIC TISSUE; ENZYMOLOGY; LUNG ALVEOLUS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE;

BIOMECHANICAL PHENOMENA; ELASTIC TISSUE; HUMANS; HYALURONIC ACID; MODELS, BIOLOGICAL; MURAMIDASE; PULMONARY ALVEOLI; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE;

EID: 84933671983     PISSN: 03069877     EISSN: 15322777     Source Type: Journal    
DOI: 10.1016/j.mehy.2015.02.015     Document Type: Article

References (26)

1. Hogg J.C., Timens W. The pathology of chronic obstructive pulmonary disease. Annu Rev Pathol 2009, 4:435-459.
2. Tuder R.M., Petrache I. Pathogenesis of chronic obstructive pulmonary disease. J Clin Invest 2012, 122:2749-2755.
3. Abboud R.T., Vimalanathan S. Pathogenesis of COPD. Part I. The role of protease-antiprotease imbalance in emphysema. Int J Tuberc Lung Dis 2008, 12:361-367.
4. Shteyngart B., Chaiwiriyakul S., Wong J., Cantor J.O. Preferential binding of lysozyme to elastic fibers in pulmonary emphysema. Thorax 1998, 53:193-196.
5. Yoshinaga E., Kawada A., Ono K., et al. NE{open}-(carboxymethyl)lysine modification of elastin alters its biological properties: implications for the accumulation of abnormal elastic fibers in actinic elastosis. J Invest Dermatol 2012, 132:315-323.
6. Dicker K.T., Gurski L.A., Pradhan-Bhatt S., Witt R.L., Farach-Carson M.C., Jia X. Hyaluronan: a simple polysaccharide with diverse biological functions. Acta Biomater 2014, 10:1558-1570.
7. Jiang D., Liang J., Noble P.W. Regulation of non-infectious lung injury, inflammation, and repair by the extracellular matrix glycosaminoglycan hyaluronan. Anat Rec (Hoboken) 2010, 293:982-985.
8. Cantor J.O., Cerreta J.M., Armand G., Turino G.M. Aerosolized hyaluronic acid decreases alveolar injury induced by human neutrophil elastase. Proc Soc Exp Biol Med 1998, 217:471-475.
9. Cantor J.O., Cerreta J.M., Keller S., Turino G.M. Modulation of airspace enlargement in elastase-induced emphysema by intratracheal instillment of hyaluronidase and hyaluronic acid. Exp Lung Res 1995, 21:423-436.
10. Cantor J.O., Cerreta J.M., Ochoa M., et al. Aerosolized hyaluronan limits airspace enlargement in a mouse model of cigarette smoke-induced pulmonary emphysema. Exp Lung Res 2005, 31:417-430.
11. Cantor J.O., Shteyngart B., Cerreta J.M., Turino G.M. The effect of lysozyme on elastase-mediated injury. Exp Biol Med 2002, 227:108-113.
12. Li B., Alonso D.O., Bennion B.J., Daggett V. Hydrophobic hydration is an important source of elasticity in elastin-based biopolymers. J Am Chem Soc 2001, 123:11991-11998.
13. Lillie M.A., Chalmers G.W., Gosline J.M. Elastin dehydration through the liquid and the vapor phase: a comparison of osmotic stress models. Biopolymers 1996, 39:627-639.
14. Gosline J.M. The role of hydrophobic interactions in the swelling of elastin. Advances in experimental medicine and biology 1977, vol. 79:621-631. Plenum, New York.
15. Kendall K. Molecular adhesion and its applications 2001, 103-131. Plenum, New York.
16. Hoeve C.A.J. The elasticity in the presence of diluents. Advances in experimental medicine and biology 1977, vol. 79:607-619. Plenum, New York.
17. Water J.J., Schack M.M., Velazquez-Campoy A., Maltesen M.J., van de Weert M., Jorgensen L., et al. Complex coacervates of hyaluronic acid and lysozyme: effect on protein structure and physical stability. Eur J Pharm Biopharm 2014, 88:325-331.
18. Miller M., Cho J.Y., Pham A., Friedman P.J., Ramsdell J., Broide D.H. Persistent airway inflammation and emphysema progression on CT scan in ex-smokers observed for 4 years. Chest 2011, 139:1380-1387.
19. Cocci F., Miniati M., Monti S., et al. Urinary desmosine excretion is inversely correlated with the extent of emphysema in patients with chronic obstructive pulmonary disease. Int J Biochem Cell Biol 2002, 34:594-604.
20. Pierce J.A., Hocon J.B., Ebert R.V. The collagen and elastin content of the lung in emphysema. Ann Intern Med 1961, 55:210-222.
21. Johnson J.R., Andrews F.A. Lung scleroproteins in age and emphysema. Chest 1970, 57:239-244.
22. Fukuda Y., Masuda Y., Ishizaki M., Masugi Y., Ferrans V.J. Morphogenesis of abnormal elastic fibers in lungs of patients with panacinar and centriacinar emphysema. Hum Pathol 1989, 20:652-659.
23. Deslee G., Woods J.C., Moore C.M., Liu L., Conradi S.H., Milne M., et al. Elastin expression in very severe human COPD. Eur Respir J 2009, 34:324-331.
24. Park P.W., Biedermann K., Mecham L., Bissett D.L., Mecham R.P. Lysozyme binds to elastin and protects elastin from elastase-mediated degradation. J Invest Dermatol 1996, 106:1075-1080.
25. Masakichi M., Hideo A., Atsunobu Y., et al. A study on glycosaminoglycans in a case of pulmonary emphysema. Z Erkr Atmungsorgane 1975, 143:270-276.
26. Konno K., Arai H., Motomiya M., et al. A biochemical study on glycosaminoglycans (mucopolysaccharides) in emphysematous and in aged lungs. Am Rev Respir Dis 1982, 126:797-801.