N-ε(Carboxymethyl)lysine modification of elastin alters its biological properties: Implications for the accumulation of abnormal elastic fibers in actinic elastosis

Journal of Investigative Dermatology

Volumn 132, Issue 2, 2012, Pages 315-323

  Yoshinaga, Eiji ^a   Kawada, Akira ^a   Ono, Koji ^b   Fujimoto, Eita ^b   Wachi, Hiroshi ^c   Harumiya, Satoru ^d   Nagai, Ryoji ^e   Tajima, Shingo ^b  

^a KINKI UNIVERSITY   (Japan)

^b NATIONAL DEFENSE MEDICAL COLLEGE   (Japan)

^c HOSHI UNIVERSITY   (Japan)

^d TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^e JAPAN WOMEN'S UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

6 N CARBOXYMETHYLLYSINE; ALPHA ELASTIN; ELASTIN; LEUKOCYTE ELASTASE; LYSOZYME; UNCLASSIFIED DRUG; DRUG DERIVATIVE; LYSINE; N(6) CARBOXYMETHYLLYSINE; N(6)-CARBOXYMETHYLLYSINE;

ACTINIC ELASTOSIS; ADULT; ARTICLE; CONTROLLED STUDY; ELASTIC FIBER; ELASTICITY; ELASTOSIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MOLECULAR SIZE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN GLYCOSYLATION; PROTEIN MODIFICATION; PROTEIN PROTEIN INTERACTION; TEMPERATURE DEPENDENCE; TENSILE STRENGTH; ULTRAVIOLET IRRADIATION; CUTANEOUS PARAMETERS; ELASTIC TISSUE; MALE; METABOLISM; PATHOLOGY; PHYSIOLOGY; SCANNING ELECTRON MICROSCOPY; SUNLIGHT; ULTRAVIOLET RADIATION;

ADULT; ELASTIC TISSUE; ELASTIN; HUMANS; LEUKOCYTE ELASTASE; LYSINE; MALE; MICROSCOPY, ELECTRON, SCANNING; MURAMIDASE; SKIN AGING; SUNLIGHT; ULTRAVIOLET RAYS;

EID: 84855961896     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2011.298     Document Type: Article

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