-
1
-
-
77953160144
-
Minireview: Update on incretin biology: Focus on glucagon-like peptide-1
-
Brubaker PL. Minireview: update on incretin biology: focus on glucagon-like peptide-1. Endocrinology 2010;151:1984-1989.
-
(2010)
Endocrinology
, vol.151
, pp. 1984-1989
-
-
Brubaker, P.L.1
-
2
-
-
84878808238
-
Pharmacology, physiology, and mechanisms of incretin hormone action
-
Campbell JE, Drucker DJ. Pharmacology, physiology, and mechanisms of incretin hormone action. Cell Metab 2013;17:819-837.
-
(2013)
Cell Metab
, vol.17
, pp. 819-837
-
-
Campbell, J.E.1
Drucker, D.J.2
-
3
-
-
84856918822
-
The therapeutic potential of GPR119 agonists for type 2 diabetes
-
Ohishi T, Yoshida S. The therapeutic potential of GPR119 agonists for type 2 diabetes. Expert Opin Investig Drugs 2012;21:321-328.
-
(2012)
Expert Opin Investig Drugs
, vol.21
, pp. 321-328
-
-
Ohishi, T.1
Yoshida, S.2
-
4
-
-
65549142522
-
GPR119 is essential for oleoylethanolamideinduced glucagon-like peptide-1 secretion from the intestinal enteroendocrine L-cell
-
Lauffer LM, Iakoubov R, Brubaker PL. GPR119 is essential for oleoylethanolamideinduced glucagon-like peptide-1 secretion from the intestinal enteroendocrine L-cell. Diabetes 2009;58:1058-1066.
-
(2009)
Diabetes
, vol.58
, pp. 1058-1066
-
-
Lauffer, L.M.1
Iakoubov, R.2
Brubaker, P.L.3
-
5
-
-
0036724256
-
Glucose-sensing in glucagon-like peptide-1- secreting cells
-
Reimann F, Gribble FM. Glucose-sensing in glucagon-like peptide-1- secreting cells. Diabetes 2002;51:2757-2763.
-
(2002)
Diabetes
, vol.51
, pp. 2757-2763
-
-
Reimann, F.1
Gribble, F.M.2
-
6
-
-
55849125147
-
Role of central nervous system glucagon-like Peptide-1 receptors in enteric glucose sensing
-
Knauf C, Cani PD, Kim DH, et al. Role of central nervous system glucagon-like Peptide-1 receptors in enteric glucose sensing. Diabetes 2008;57:2603-2612.
-
(2008)
Diabetes
, vol.57
, pp. 2603-2612
-
-
Knauf, C.1
Cani, P.D.2
Kim, D.H.3
-
7
-
-
0032982267
-
Role of the vagus nerve in mediating proximal nutrient-induced glucagon-like peptide-1 secretion
-
Rocca AS, Brubaker PL. Role of the vagus nerve in mediating proximal nutrient-induced glucagon-like peptide-1 secretion. Endocrinology 1999;140: 1687-1694.
-
(1999)
Endocrinology
, vol.140
, pp. 1687-1694
-
-
Rocca, A.S.1
Brubaker, P.L.2
-
8
-
-
0025830648
-
Regulation of intestinal proglucagon-derived peptide secretion by intestinal regulatory peptides
-
Brubaker PL. Regulation of intestinal proglucagon-derived peptide secretion by intestinal regulatory peptides. Endocrinology 1991;128:3175-3182.
-
(1991)
Endocrinology
, vol.128
, pp. 3175-3182
-
-
Brubaker, P.L.1
-
9
-
-
0031732608
-
Glucagon-like-peptide-1 secretion from canine L-cells is increased by glucose-dependent-insulinotropic peptide but unaffected by glucose
-
Damholt AB, Buchan AM, Kofod H. Glucagon-like-peptide-1 secretion from canine L-cells is increased by glucose-dependent-insulinotropic peptide but unaffected by glucose. Endocrinology 1998;139:2085-2091.
-
(1998)
Endocrinology
, vol.139
, pp. 2085-2091
-
-
Damholt, A.B.1
Buchan, A.M.2
Kofod, H.3
-
10
-
-
76149116843
-
Role of fat hydrolysis in regulating glucagon-like Peptide-1 secretion
-
Beglinger S, Drewe J, Schirra J, Göke B, D'Amato M, Beglinger C. Role of fat hydrolysis in regulating glucagon-like Peptide-1 secretion. J Clin Endocrinol Metab 2010;95:879-886.
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 879-886
-
-
Beglinger, S.1
Drewe, J.2
Schirra, J.3
Göke, B.4
D'Amato, M.5
Beglinger, C.6
-
11
-
-
0037315423
-
Role of leptin in the regulation of glucagon-like peptide-1 secretion
-
Anini Y, Brubaker PL. Role of leptin in the regulation of glucagon-like peptide-1 secretion. Diabetes 2003;52:252-259.
-
(2003)
Diabetes
, vol.52
, pp. 252-259
-
-
Anini, Y.1
Brubaker, P.L.2
-
12
-
-
59649088932
-
Insulin regulates glucagon-like peptide-1 secretion from the enteroendocrine L cell
-
Lim GE, Huang GJ, Flora N, LeRoith D, Rhodes CJ, Brubaker PL. Insulin regulates glucagon-like peptide-1 secretion from the enteroendocrine L cell. Endocrinology 2009;150:580-591.
-
(2009)
Endocrinology
, vol.150
, pp. 580-591
-
-
Lim, G.E.1
Huang, G.J.2
Flora, N.3
LeRoith, D.4
Rhodes, C.J.5
Brubaker, P.L.6
-
13
-
-
0035095031
-
Monounsaturated fatty acid diets improve glycemic tolerance through increased secretion of glucagon-like peptide-1
-
Rocca AS, LaGreca J, Kalitsky J, Brubaker PL. Monounsaturated fatty acid diets improve glycemic tolerance through increased secretion of glucagon-like peptide-1. Endocrinology 2001;142:1148-1155.
-
(2001)
Endocrinology
, vol.142
, pp. 1148-1155
-
-
Rocca, A.S.1
LaGreca, J.2
Kalitsky, J.3
Brubaker, P.L.4
-
14
-
-
0035433977
-
A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans
-
Cummings DE, Purnell JQ, Frayo RS, Schmidova K, Wisse BE, Weigle DS. A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes 2001;50:1714-1719.
-
(2001)
Diabetes
, vol.50
, pp. 1714-1719
-
-
Cummings, D.E.1
Purnell, J.Q.2
Frayo, R.S.3
Schmidova, K.4
Wisse, B.E.5
Weigle, D.S.6
-
15
-
-
32544448074
-
Subcutaneous administration of ghrelin stimulates energy intake in healthy lean human volunteers
-
Lond
-
Druce MR, Neary NM, Small CJ, et al. Subcutaneous administration of ghrelin stimulates energy intake in healthy lean human volunteers. Int J Obes (Lond) 2006;30:293-296.
-
(2006)
Int J Obes
, vol.30
, pp. 293-296
-
-
Druce, M.R.1
Neary, N.M.2
Small, C.J.3
-
17
-
-
80051691117
-
Ghrelin-induced adiposity is independent of orexigenic effects
-
Perez-Tilve D, Heppner K, Kirchner H, et al. Ghrelin-induced adiposity is independent of orexigenic effects. FASEB J 2011;25:2814-2822.
-
(2011)
FASEB J
, vol.25
, pp. 2814-2822
-
-
Perez-Tilve, D.1
Heppner, K.2
Kirchner, H.3
-
18
-
-
84884678791
-
Ghrelin requires p53 to stimulate lipid storage in fat and liver
-
Porteiro B, Díaz-Ruíz A, Martínez G, et al. Ghrelin requires p53 to stimulate lipid storage in fat and liver. Endocrinology 2013;154:3671-3679.
-
(2013)
Endocrinology
, vol.154
, pp. 3671-3679
-
-
Porteiro, B.1
Díaz-Ruíz, A.2
Martínez, G.3
-
19
-
-
67349175270
-
Acylated and desacyl ghrelin stimulate lipid accumulation in human visceral adipocytes
-
Lond
-
Rodríguez A, Gómez-Ambrosi J, Catalán V, et al. Acylated and desacyl ghrelin stimulate lipid accumulation in human visceral adipocytes. Int J Obes (Lond) 2009;33:541-552.
-
(2009)
Int J Obes
, vol.33
, pp. 541-552
-
-
Rodríguez, A.1
Gómez-Ambrosi, J.2
Catalán, V.3
-
20
-
-
77951666372
-
Obese adolescents show impaired meal responses of the appetite-regulating hormones ghrelin and PYY
-
Silver Spring
-
Mittelman SD, Klier K, Braun S, Azen C, Geffner ME, Buchanan TA. Obese adolescents show impaired meal responses of the appetite-regulating hormones ghrelin and PYY. Obesity (Silver Spring) 2010;18:918-925.
-
(2010)
Obesity
, vol.18
, pp. 918-925
-
-
Mittelman, S.D.1
Klier, K.2
Braun, S.3
Azen, C.4
Geffner, M.E.5
Buchanan, T.A.6
-
21
-
-
0035082265
-
Circulating ghrelin levels are decreased in human obesity
-
Tschöp M, Weyer C, Tataranni PA, Devanarayan V, Ravussin E, Heiman ML. Circulating ghrelin levels are decreased in human obesity. Diabetes 2001;50:707-709.
-
(2001)
Diabetes
, vol.50
, pp. 707-709
-
-
Tschöp, M.1
Weyer, C.2
Tataranni, P.A.3
Devanarayan, V.4
Ravussin, E.5
Heiman, M.L.6
-
22
-
-
0030055478
-
Attenuated GLP-1 secretion in obesity: Cause or consequence?
-
Ranganath LR, Beety JM, Morgan LM, Wright JW, Howland R, Marks V. Attenuated GLP-1 secretion in obesity: cause or consequence? Gut 1996;38:916-919.
-
(1996)
Gut
, vol.38
, pp. 916-919
-
-
Ranganath, L.R.1
Beety, J.M.2
Morgan, L.M.3
Wright, J.W.4
Howland, R.5
Marks, V.6
-
23
-
-
0031922709
-
Identification of glucagon-like peptide 1 (GLP-1) actions essential for glucose homeostasis in mice with disruption of GLP-1 receptor signaling
-
Scrocchi LA, Marshall BA, Cook SM, Brubaker PL, Drucker DJ. Identification of glucagon-like peptide 1 (GLP-1) actions essential for glucose homeostasis in mice with disruption of GLP-1 receptor signaling. Diabetes 1998;47:632-639.
-
(1998)
Diabetes
, vol.47
, pp. 632-639
-
-
Scrocchi, L.A.1
Marshall, B.A.2
Cook, S.M.3
Brubaker, P.L.4
Drucker, D.J.5
-
24
-
-
0028575660
-
Activation of proglucagon gene transcription by protein kinase-A in a novel mouse enteroendocrine cell line
-
Drucker DJ, Jin T, Asa SL, Young TA, Brubaker PL. Activation of proglucagon gene transcription by protein kinase-A in a novel mouse enteroendocrine cell line. Mol Endocrinol 1994;8:1646-1655.
-
(1994)
Mol Endocrinol
, vol.8
, pp. 1646-1655
-
-
Drucker, D.J.1
Jin, T.2
Asa, S.L.3
Young, T.A.4
Brubaker, P.L.5
-
25
-
-
33751069321
-
Meat hydrolysate and essential amino acid-induced glucagonlike peptide-1 secretion, in the human NCI-H716 enteroendocrine cell line, is regulated by extracellular signal-regulated kinase1/2 and p38 mitogen- Activated protein kinases
-
Reimer RA. Meat hydrolysate and essential amino acid-induced glucagonlike peptide-1 secretion, in the human NCI-H716 enteroendocrine cell line, is regulated by extracellular signal-regulated kinase1/2 and p38 mitogen- Activated protein kinases. J Endocrinol 2006;191:159-170.
-
(2006)
J Endocrinol
, vol.191
, pp. 159-170
-
-
Reimer, R.A.1
-
26
-
-
84900526973
-
Long- Term metabolic benefits of exenatide in mice are mediated solely via the known glucagon-like peptide 1 receptor
-
Tatarkiewicz K, Sablan EJ, Polizzi CJ, Villescaz C, Parkes DG. Long- Term metabolic benefits of exenatide in mice are mediated solely via the known glucagon-like peptide 1 receptor. Am J Physiol Regul Integr Comp Physiol 2014; 306:R490-R498.
-
(2014)
Am J Physiol Regul Integr Comp Physiol
, vol.306
, pp. R490-R498
-
-
Tatarkiewicz, K.1
Sablan, E.J.2
Polizzi, C.J.3
Villescaz, C.4
Parkes, D.G.5
-
27
-
-
79960129197
-
Alpha cells secrete acetylcholine as a non-neuronal paracrine signal priming beta cell function in humans
-
Rodriguez-Diaz R, Dando R, Jacques-Silva MC, et al. Alpha cells secrete acetylcholine as a non-neuronal paracrine signal priming beta cell function in humans. Nat Med 2011;17:888-892.
-
(2011)
Nat Med
, vol.17
, pp. 888-892
-
-
Rodriguez-Diaz, R.1
Dando, R.2
Jacques-Silva, M.C.3
-
28
-
-
80054833327
-
GABA coordinates with insulin in regulating secretory function in pancreatic INS-1 b-cells
-
Bansal P, Wang S, Liu S, Xiang YY, Lu WY, Wang Q. GABA coordinates with insulin in regulating secretory function in pancreatic INS-1 b-cells. PLoS ONE 2011;6:e26225.
-
(2011)
PLoS ONE
, vol.6
, pp. e26225
-
-
Bansal, P.1
Wang, S.2
Liu, S.3
Xiang, Y.Y.4
Lu, W.Y.5
Wang, Q.6
-
29
-
-
84884180095
-
Minor role of mitochondrial respiration for fatty- Acid induced insulin secretion
-
Schulz N, Kluth O, Jastroch M, Schürmann A. Minor role of mitochondrial respiration for fatty- Acid induced insulin secretion. Int J Mol Sci 2013;14:18989- 18998.
-
(2013)
Int J Mol Sci
, vol.14
, pp. 18989-18998
-
-
Schulz, N.1
Kluth, O.2
Jastroch, M.3
Schürmann, A.4
-
30
-
-
79954994716
-
Purification of a candidate gonadotrophin surge-inhibiting/attenuating factor (GnSIF/AF) showing MAPK as a possible target
-
Hendriks ML, Lambalk CB, Helder MN, de Koning J. Purification of a candidate gonadotrophin surge-inhibiting/attenuating factor (GnSIF/AF) showing MAPK as a possible target. Mol Reprod Dev 2011;78:292-304.
-
(2011)
Mol Reprod Dev
, vol.78
, pp. 292-304
-
-
Hendriks, M.L.1
Lambalk, C.B.2
Helder, M.N.3
De Koning, J.4
-
31
-
-
21044457222
-
Ghrelin treatment reverses the reduction in weight gain and body fat in gastrectomised mice
-
Dornonville de la Cour C, Lindqvist A, Egecioglu E, et al. Ghrelin treatment reverses the reduction in weight gain and body fat in gastrectomised mice. Gut 2005;54:907-913.
-
(2005)
Gut
, vol.54
, pp. 907-913
-
-
De La Dornonville, C.C.1
Lindqvist, A.2
Egecioglu, E.3
-
32
-
-
29244486778
-
Acylated ghrelin stimulates food intake in the fed and fasted states but desacylated ghrelin has no effect
-
Neary NM, Druce MR, Small CJ, Bloom SR. Acylated ghrelin stimulates food intake in the fed and fasted states but desacylated ghrelin has no effect. Gut 2006;55:135.
-
(2006)
Gut
, vol.55
, pp. 135
-
-
Neary, N.M.1
Druce, M.R.2
Small, C.J.3
Bloom, S.R.4
-
33
-
-
9444264700
-
Endogenous ghrelin in pancreatic islets restricts insulin release by attenuating Ca2+ signaling in b-cells: Implication in the glycemic control in rodents
-
Dezaki K, Hosoda H, Kakei M, et al. Endogenous ghrelin in pancreatic islets restricts insulin release by attenuating Ca2+ signaling in b-cells: implication in the glycemic control in rodents. Diabetes 2004;53:3142-3151.
-
(2004)
Diabetes
, vol.53
, pp. 3142-3151
-
-
Dezaki, K.1
Hosoda, H.2
Kakei, M.3
-
34
-
-
84903157828
-
Acute administration of unacylated ghrelin has no effect on Basal or stimulated insulin secretion in healthy humans
-
Tong J, Davis HW, Summer S, et al. Acute administration of unacylated ghrelin has no effect on Basal or stimulated insulin secretion in healthy humans. Diabetes 2014;63:2309-2319.
-
(2014)
Diabetes
, vol.63
, pp. 2309-2319
-
-
Tong, J.1
Davis, H.W.2
Summer, S.3
-
35
-
-
5644221730
-
Secretion of incretin hormones (GIP and GLP-1) and incretin effect after oral glucose in first-degree relatives of patients with type 2 diabetes
-
Nauck MA, El-Ouaghlidi A, Gabrys B, et al. Secretion of incretin hormones (GIP and GLP-1) and incretin effect after oral glucose in first-degree relatives of patients with type 2 diabetes. Regul Pept 2004;122:209-217.
-
(2004)
Regul Pept
, vol.122
, pp. 209-217
-
-
Nauck, M.A.1
El-Ouaghlidi, A.2
Gabrys, B.3
-
36
-
-
0022461548
-
Incretin effects of increasing glucose loads in man calculated from venous insulin and C-peptide responses
-
Nauck MA, Homberger E, Siegel EG, et al. Incretin effects of increasing glucose loads in man calculated from venous insulin and C-peptide responses. J Clin Endocrinol Metab 1986;63:492-498.
-
(1986)
J Clin Endocrinol Metab
, vol.63
, pp. 492-498
-
-
Nauck, M.A.1
Homberger, E.2
Siegel, E.G.3
-
37
-
-
84864289974
-
Exogenous and endogenous ghrelin counteracts GLP-1 action to stimulate cAMP signaling and insulin secretion in islet b-cells
-
Damdindorj B, Dezaki K, Kurashina T, et al. Exogenous and endogenous ghrelin counteracts GLP-1 action to stimulate cAMP signaling and insulin secretion in islet b-cells. FEBS Lett 2012;586:2555-2562.
-
(2012)
FEBS Lett
, vol.586
, pp. 2555-2562
-
-
Damdindorj, B.1
Dezaki, K.2
Kurashina, T.3
-
39
-
-
0034687376
-
Ghrelin induces adiposity in rodents
-
Tschöp M, Smiley DL, Heiman ML. Ghrelin induces adiposity in rodents. Nature 2000;407:908-913.
-
(2000)
Nature
, vol.407
, pp. 908-913
-
-
Tschöp, M.1
Smiley, D.L.2
Heiman, M.L.3
-
40
-
-
0035514596
-
Ghrelin causes hyperphagia and obesity in rats
-
Wren AM, Small CJ, Abbott CR, et al. Ghrelin causes hyperphagia and obesity in rats. Diabetes 2001;50:2540-2547.
-
(2001)
Diabetes
, vol.50
, pp. 2540-2547
-
-
Wren, A.M.1
Small, C.J.2
Abbott, C.R.3
-
41
-
-
34548386070
-
Effects of ghrelin administration on decreased growth hormone status in obese animals
-
Iwakura H, Akamizu T, Ariyasu H, et al. Effects of ghrelin administration on decreased growth hormone status in obese animals. Am J Physiol Endocrinol Metab 2007;293:E819-E825.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.293
, pp. E819-E825
-
-
Iwakura, H.1
Akamizu, T.2
Ariyasu, H.3
-
42
-
-
33744485247
-
Regulation of ERK1/2 activity by ghrelinactivated growth hormone secretagogue receptor 1A involves a PLC/PKCvarepsilon pathway
-
Mousseaux D, Le Gallic L, Ryan J, et al. Regulation of ERK1/2 activity by ghrelinactivated growth hormone secretagogue receptor 1A involves a PLC/PKCvarepsilon pathway. Br J Pharmacol 2006;148:350-365.
-
(2006)
Br J Pharmacol
, vol.148
, pp. 350-365
-
-
Mousseaux, D.1
Le, G.L.2
Ryan, J.3
-
43
-
-
84875481056
-
The effect of ghrelin on cell proliferation in small intestinal IEC-6 cells
-
Yu H, Xu G, Fan X. The effect of ghrelin on cell proliferation in small intestinal IEC-6 cells. Biomed Pharmacother 2013;67:235-239.
-
(2013)
Biomed Pharmacother
, vol.67
, pp. 235-239
-
-
Yu, H.1
Xu, G.2
Fan, X.3
-
44
-
-
84862576179
-
The ghrelin gene products and exendin-4 promote survival of human pancreatic islet endothelial cells in hyperglycaemic conditions, through phosphoinositide 3-kinase/Akt, extracellular signal-related kinase (ERK)1/2 and cAMP/protein kinase A (PKA) signalling pathways
-
Favaro E, Granata R, Miceli I, et al. The ghrelin gene products and exendin-4 promote survival of human pancreatic islet endothelial cells in hyperglycaemic conditions, through phosphoinositide 3-kinase/Akt, extracellular signal-related kinase (ERK)1/2 and cAMP/protein kinase A (PKA) signalling pathways. Diabetologia 2012;55:1058-1070.
-
(2012)
Diabetologia
, vol.55
, pp. 1058-1070
-
-
Favaro, E.1
Granata, R.2
Miceli, I.3
-
45
-
-
84908626419
-
Circadian secretion of the intestinal hormone, glucagon-like peptide-1, by the rodent L-cell
-
Gil-Lozano M, Mingomataj EL, Wu WK, Ridout SA, Brubaker PL. Circadian secretion of the intestinal hormone, glucagon-like peptide-1, by the rodent L-cell. Diabetes 2014;63:3674-3685.
-
(2014)
Diabetes
, vol.63
, pp. 3674-3685
-
-
Gil-Lozano, M.1
Mingomataj, E.L.2
Wu, W.K.3
Ridout, S.A.4
Brubaker, P.L.5
-
46
-
-
71949092713
-
The rho guanosine 59- Triphosphatase, cell division cycle 42, is required for insulin-induced actin remodeling and glucagon-like peptide-1 secretion in the intestinal endocrine L cell
-
Lim GE, Xu M, Sun J, Jin T, Brubaker PL. The rho guanosine 59- Triphosphatase, cell division cycle 42, is required for insulin-induced actin remodeling and glucagon-like peptide-1 secretion in the intestinal endocrine L cell. Endocrinology 2009;150:5249-5261.
-
(2009)
Endocrinology
, vol.150
, pp. 5249-5261
-
-
Lim, G.E.1
Xu, M.2
Sun, J.3
Jin, T.4
Brubaker, P.L.5
-
47
-
-
79959761215
-
Synaptotagmin-7 as a positive regulator of glucose-induced glucagon-like peptide-1 secretion in mice
-
Gustavsson N, Wang Y, Kang Y, et al. Synaptotagmin-7 as a positive regulator of glucose-induced glucagon-like peptide-1 secretion in mice. Diabetologia 2011;54:1824-1830.
-
(2011)
Diabetologia
, vol.54
, pp. 1824-1830
-
-
Gustavsson, N.1
Wang, Y.2
Kang, Y.3
-
48
-
-
84896094444
-
Role of vesicle- Associated membrane protein 2 in exocytosis of glucagon-like peptide-1 from the murine intestinal L cell
-
Li SK, Zhu D, Gaisano HY, Brubaker PL. Role of vesicle- Associated membrane protein 2 in exocytosis of glucagon-like peptide-1 from the murine intestinal L cell. Diabetologia 2014;57:809-818.
-
(2014)
Diabetologia
, vol.57
, pp. 809-818
-
-
Li, S.K.1
Zhu, D.2
Gaisano, H.Y.3
Brubaker, P.L.4
|